FR2092639A1 - 10-(1-piperonylpiperazinoalkanoyl) phenothiazines - with specific spasmolytic,antipyretic and antiemetic activity - Google Patents
10-(1-piperonylpiperazinoalkanoyl) phenothiazines - with specific spasmolytic,antipyretic and antiemetic activityInfo
- Publication number
- FR2092639A1 FR2092639A1 FR7020381A FR7020381A FR2092639A1 FR 2092639 A1 FR2092639 A1 FR 2092639A1 FR 7020381 A FR7020381 A FR 7020381A FR 7020381 A FR7020381 A FR 7020381A FR 2092639 A1 FR2092639 A1 FR 2092639A1
- Authority
- FR
- France
- Prior art keywords
- specific
- spasmolytic
- antipyretic
- piperonylpiperazinoalkanoyl
- phenothiazines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000002048 spasmolytic effect Effects 0.000 title abstract 3
- 230000003474 anti-emetic effect Effects 0.000 title abstract 2
- 230000001754 anti-pyretic effect Effects 0.000 title abstract 2
- 239000002221 antipyretic Substances 0.000 title 1
- 239000000812 cholinergic antagonist Substances 0.000 title 1
- 150000002990 phenothiazines Chemical class 0.000 title 1
- NBOOZXVYXHATOW-UHFFFAOYSA-N 1-(1,3-benzodioxol-5-ylmethyl)piperazine Chemical compound C=1C=C2OCOC2=CC=1CN1CCNCC1 NBOOZXVYXHATOW-UHFFFAOYSA-N 0.000 abstract 1
- WJFKNYWRSNBZNX-UHFFFAOYSA-N 10H-phenothiazine Chemical compound C1=CC=C2NC3=CC=CC=C3SC2=C1 WJFKNYWRSNBZNX-UHFFFAOYSA-N 0.000 abstract 1
- 229930003347 Atropine Natural products 0.000 abstract 1
- RKUNBYITZUJHSG-UHFFFAOYSA-N Hyosciamin-hydrochlorid Natural products CN1C(C2)CCC1CC2OC(=O)C(CO)C1=CC=CC=C1 RKUNBYITZUJHSG-UHFFFAOYSA-N 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 239000002111 antiemetic agent Substances 0.000 abstract 1
- RKUNBYITZUJHSG-SPUOUPEWSA-N atropine Chemical compound O([C@H]1C[C@H]2CC[C@@H](C1)N2C)C(=O)C(CO)C1=CC=CC=C1 RKUNBYITZUJHSG-SPUOUPEWSA-N 0.000 abstract 1
- 229960000396 atropine Drugs 0.000 abstract 1
- 230000036772 blood pressure Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 230000005923 long-lasting effect Effects 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 230000002911 mydriatic effect Effects 0.000 abstract 1
- 229950000688 phenothiazine Drugs 0.000 abstract 1
- 230000036387 respiratory rate Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7020381A FR2092639A1 (en) | 1970-06-03 | 1970-06-03 | 10-(1-piperonylpiperazinoalkanoyl) phenothiazines - with specific spasmolytic,antipyretic and antiemetic activity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7020381A FR2092639A1 (en) | 1970-06-03 | 1970-06-03 | 10-(1-piperonylpiperazinoalkanoyl) phenothiazines - with specific spasmolytic,antipyretic and antiemetic activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2092639A1 true FR2092639A1 (en) | 1972-01-28 |
| FR2092639B1 FR2092639B1 (enExample) | 1973-07-13 |
Family
ID=9056619
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7020381A Granted FR2092639A1 (en) | 1970-06-03 | 1970-06-03 | 10-(1-piperonylpiperazinoalkanoyl) phenothiazines - with specific spasmolytic,antipyretic and antiemetic activity |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2092639A1 (enExample) |
-
1970
- 1970-06-03 FR FR7020381A patent/FR2092639A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FR2092639B1 (enExample) | 1973-07-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TP | Transmission of property | ||
| TP | Transmission of property | ||
| GC | Lien (pledge) constituted | ||
| GR | Lien (pledge) cancelled due to a court decision |