FR2081583A1 - Threonine proto-glutamate - as hepatoprotective agent - Google Patents
Threonine proto-glutamate - as hepatoprotective agentInfo
- Publication number
- FR2081583A1 FR2081583A1 FR7010465A FR7010465A FR2081583A1 FR 2081583 A1 FR2081583 A1 FR 2081583A1 FR 7010465 A FR7010465 A FR 7010465A FR 7010465 A FR7010465 A FR 7010465A FR 2081583 A1 FR2081583 A1 FR 2081583A1
- Authority
- FR
- France
- Prior art keywords
- threonine
- proto
- glutamate
- hepatoprotective agent
- active ingredient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 title abstract 3
- 239000004473 Threonine Substances 0.000 title abstract 3
- 239000003795 chemical substances by application Substances 0.000 title abstract 2
- 230000002443 hepatoprotective effect Effects 0.000 title abstract 2
- PXQPEWDEAKTCGB-UHFFFAOYSA-N orotic acid Chemical compound OC(=O)C1=CC(=O)NC(=O)N1 PXQPEWDEAKTCGB-UHFFFAOYSA-N 0.000 abstract 4
- 239000004480 active ingredient Substances 0.000 abstract 2
- 229960005010 orotic acid Drugs 0.000 abstract 2
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 235000013922 glutamic acid Nutrition 0.000 abstract 1
- 239000004220 glutamic acid Substances 0.000 abstract 1
- 230000003472 neutralizing effect Effects 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/557—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. orotic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7010465A FR2081583A1 (en) | 1970-03-24 | 1970-03-24 | Threonine proto-glutamate - as hepatoprotective agent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7010465A FR2081583A1 (en) | 1970-03-24 | 1970-03-24 | Threonine proto-glutamate - as hepatoprotective agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2081583A1 true FR2081583A1 (en) | 1971-12-10 |
| FR2081583B1 FR2081583B1 (cg-RX-API-DMAC10.html) | 1973-04-06 |
Family
ID=9052776
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7010465A Granted FR2081583A1 (en) | 1970-03-24 | 1970-03-24 | Threonine proto-glutamate - as hepatoprotective agent |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2081583A1 (cg-RX-API-DMAC10.html) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2449409A1 (fr) * | 1979-02-23 | 1980-09-19 | Roberti Andre | Adjuvant d'alimentation et son procede de preparation |
| WO1980002372A1 (en) * | 1979-05-07 | 1980-11-13 | Massachusetts Inst Technology | Process and composition for regulating glycine levels in the brain and spinal cord |
-
1970
- 1970-03-24 FR FR7010465A patent/FR2081583A1/fr active Granted
Non-Patent Citations (1)
| Title |
|---|
| NEANT * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2449409A1 (fr) * | 1979-02-23 | 1980-09-19 | Roberti Andre | Adjuvant d'alimentation et son procede de preparation |
| WO1980002372A1 (en) * | 1979-05-07 | 1980-11-13 | Massachusetts Inst Technology | Process and composition for regulating glycine levels in the brain and spinal cord |
| EP0028257A4 (en) * | 1979-05-07 | 1981-09-11 | Massachusetts Inst Technology | L-THREONINE FOR THE REGULATION OF GLYCIN LEVELS IN THE BRAIN AND SPINAL CORD. |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2081583B1 (cg-RX-API-DMAC10.html) | 1973-04-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |