FR2079314A1 - 2, 4-dioxo-1, 2, 3, 4, 5, 6, 7, 8-octahydrobenzothieno - (2, 3-d) pyrimidines - with antiinflammatory, analgesic, antitussive - Google Patents

2, 4-dioxo-1, 2, 3, 4, 5, 6, 7, 8-octahydrobenzothieno - (2, 3-d) pyrimidines - with antiinflammatory, analgesic, antitussive

Info

Publication number
FR2079314A1
FR2079314A1 FR7006702A FR7006702A FR2079314A1 FR 2079314 A1 FR2079314 A1 FR 2079314A1 FR 7006702 A FR7006702 A FR 7006702A FR 7006702 A FR7006702 A FR 7006702A FR 2079314 A1 FR2079314 A1 FR 2079314A1
Authority
FR
France
Prior art keywords
octahydrobenzothieno
antitussive
pyrimidines
antiinflammatory
dioxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7006702A
Other languages
French (fr)
Other versions
FR2079314B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CENTRE ETD IND PHARMA
Original Assignee
CENTRE ETD IND PHARMA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CENTRE ETD IND PHARMA filed Critical CENTRE ETD IND PHARMA
Publication of FR2079314A1 publication Critical patent/FR2079314A1/en
Application granted granted Critical
Publication of FR2079314B1 publication Critical patent/FR2079314B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Compounds of formula and their acid addition and quaternary ammonium salts, where R = H, 1-6C alkyl or aryl, aralkyl (is not > C10) in which the aryl rings are opt. substd. by OH, NH2, 1-6C alkyl or halogen. Specifically claimed are I (R=H, phenyl). Prepared by treating 2-amino-4,5,6,7-tetrahydrobenzo (b) thiophen-3-carboxylic acid derivatives with carbonic acid derivatives e.g. phosgene, phenyl isocyanate, ethyl chloroformate to give (I) directly or after a cyclisation stage depending on the reagents used.
FR7006702A 1970-02-09 1970-02-25 2, 4-dioxo-1, 2, 3, 4, 5, 6, 7, 8-octahydrobenzothieno - (2, 3-d) pyrimidines - with antiinflammatory, analgesic, antitussive Granted FR2079314A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT114870A AT290525B (en) 1970-02-09 1970-02-09 Process for the preparation of the new 2,4-dioxo-1,2,3,4,5,6,7,8-octahydro- [1] benzothieno [2,3-d] pyrimidine and its new 3-phenyl derivative

Publications (2)

Publication Number Publication Date
FR2079314A1 true FR2079314A1 (en) 1971-11-12
FR2079314B1 FR2079314B1 (en) 1974-01-11

Family

ID=3507641

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7006702A Granted FR2079314A1 (en) 1970-02-09 1970-02-25 2, 4-dioxo-1, 2, 3, 4, 5, 6, 7, 8-octahydrobenzothieno - (2, 3-d) pyrimidines - with antiinflammatory, analgesic, antitussive

Country Status (2)

Country Link
AT (1) AT290525B (en)
FR (1) FR2079314A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2128348A1 (en) * 1971-03-08 1972-10-20 Centre Etd Ind Pharma Mercapto-thienopyrimidine derivs - with sedative antitussive and hypocholesterolaemic activity

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2128348A1 (en) * 1971-03-08 1972-10-20 Centre Etd Ind Pharma Mercapto-thienopyrimidine derivs - with sedative antitussive and hypocholesterolaemic activity

Also Published As

Publication number Publication date
AT290525B (en) 1971-06-11
FR2079314B1 (en) 1974-01-11

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Legal Events

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