FR2073338A1 - 6-(methyleneamino)-penicillanic acid derivs - Google Patents
6-(methyleneamino)-penicillanic acid derivsInfo
- Publication number
- FR2073338A1 FR2073338A1 FR7040428A FR7040428A FR2073338A1 FR 2073338 A1 FR2073338 A1 FR 2073338A1 FR 7040428 A FR7040428 A FR 7040428A FR 7040428 A FR7040428 A FR 7040428A FR 2073338 A1 FR2073338 A1 FR 2073338A1
- Authority
- FR
- France
- Prior art keywords
- alkyl
- heterocyclic
- penicillanic acid
- residue
- methyleneamino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/02—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Penicillanic acid derivs. of formula (I) : (where R1 and R2 = an aliphatic hydrocarbon residue, a mono- or bi-cyclic aryl residue, aralkyl, cycloalkyl, cycloalkylalkyl, a heterocyclic or heterocyclic substd. alkyl gp., or R1R2N = a heterocyclic residue and R4 = H, alkyl, aryl, aralkyl, cycloalkylalkyl, haloalkyl, O-alkyl, alkanoyl, aroyl, CN, CO2 alkyl or acyloxymethyl) and salts of (I), are antibacterials of low toxicity. (I) are prepd. by condensing (a) 6-aminopenicillanic acid (II) with a reactive amide or thioamide deriv. : R1R2NCH=R5, or (b) a reactive deriv. of (III) with an amine R1R2NH.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB5520969 | 1969-11-11 | ||
GB33211/70A GB1293590A (en) | 1969-11-11 | 1969-11-11 | New penicillanic acid derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2073338A1 true FR2073338A1 (en) | 1971-10-01 |
FR2073338B1 FR2073338B1 (en) | 1974-02-15 |
Family
ID=26261769
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7040428A Granted FR2073338A1 (en) | 1969-11-11 | 1970-11-10 | 6-(methyleneamino)-penicillanic acid derivs |
Country Status (22)
Country | Link |
---|---|
JP (1) | JPS518955B1 (en) |
AT (1) | AT301026B (en) |
BE (1) | BE758782A (en) |
BG (1) | BG18619A3 (en) |
CH (2) | CH559752A5 (en) |
CS (1) | CS166020B2 (en) |
DE (1) | DE2055531C3 (en) |
DK (1) | DK135127B (en) |
ES (1) | ES385437A1 (en) |
FI (1) | FI54601C (en) |
FR (1) | FR2073338A1 (en) |
HU (1) | HU162440B (en) |
IE (1) | IE34620B1 (en) |
IL (1) | IL35490A (en) |
IT (1) | IT1044209B (en) |
LU (1) | LU62031A1 (en) |
NL (1) | NL168227C (en) |
NO (1) | NO137826C (en) |
PL (1) | PL90581B1 (en) |
RO (2) | RO56878A (en) |
SE (1) | SE397355B (en) |
SU (1) | SU406362A3 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2296638A1 (en) * | 1975-01-06 | 1976-07-30 | Inst Organicheskogo Sinteza Ak | PROCESS FOR PREPARING 6-B-AMIDINOPENICILLANIC ACID DERIVATIVES |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL79157B1 (en) * | 1970-12-22 | 1975-06-30 | ||
GB1364672A (en) * | 1971-06-09 | 1974-08-29 | Beecham Group Ltd | Penicillins |
GB1427139A (en) * | 1972-03-13 | 1976-03-10 | Astra Laekemedel Ab | Penicillins |
GB1417099A (en) * | 1973-02-02 | 1975-12-10 | Leo Pharm Prod Ltd | Method for the production of derivatives of 6-aminopenicillanic acid |
GB1579931A (en) * | 1976-04-15 | 1980-11-26 | Leo Pharm Prod Ltd | Bis-penicillanoyl-oxy-alkanes |
TWI375678B (en) | 2005-06-09 | 2012-11-01 | Yakult Honsha Kk | A method of preparation of a tricyclic ketone |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3135755A (en) * | 1961-11-20 | 1964-06-02 | Hoffmann La Roche | Pyrimidine formamidines of primary amines |
US3322781A (en) * | 1963-10-18 | 1967-05-30 | Bristol Myers Co | 6-(substituted-hydroxyamidino)-penicillanic acids |
CH480792A (en) * | 1967-01-26 | 1969-11-15 | Ciba Geigy | Pesticides |
-
0
- BE BE758782D patent/BE758782A/en not_active IP Right Cessation
-
1970
- 1970-10-20 IL IL35490A patent/IL35490A/en unknown
- 1970-10-22 IE IE1359/70A patent/IE34620B1/en unknown
- 1970-11-05 AT AT995970A patent/AT301026B/en not_active IP Right Cessation
- 1970-11-05 CH CH1644070A patent/CH559752A5/xx not_active IP Right Cessation
- 1970-11-05 CH CH1113074A patent/CH559753A5/xx not_active IP Right Cessation
- 1970-11-06 DK DK565070AA patent/DK135127B/en not_active IP Right Cessation
- 1970-11-09 SU SU1489793A patent/SU406362A3/ru active
- 1970-11-10 RO RO64921A patent/RO56878A/ro unknown
- 1970-11-10 PL PL1970144350A patent/PL90581B1/en unknown
- 1970-11-10 LU LU62031D patent/LU62031A1/xx unknown
- 1970-11-10 NL NLAANVRAGE7016435,A patent/NL168227C/en not_active IP Right Cessation
- 1970-11-10 RO RO72470A patent/RO60563A/ro unknown
- 1970-11-10 CS CS7560A patent/CS166020B2/cs unknown
- 1970-11-10 NO NO4290/70A patent/NO137826C/en unknown
- 1970-11-10 SE SE7015181A patent/SE397355B/en unknown
- 1970-11-10 IT IT70739/70A patent/IT1044209B/en active
- 1970-11-10 FR FR7040428A patent/FR2073338A1/en active Granted
- 1970-11-11 BG BG016025A patent/BG18619A3/en unknown
- 1970-11-11 HU HULO372A patent/HU162440B/hu not_active IP Right Cessation
- 1970-11-11 FI FI3032/70A patent/FI54601C/en active
- 1970-11-11 ES ES385437A patent/ES385437A1/en not_active Expired
- 1970-11-11 DE DE2055531A patent/DE2055531C3/en not_active Expired
- 1970-11-11 JP JP45099009A patent/JPS518955B1/ja active Pending
Non-Patent Citations (1)
Title |
---|
NEANT * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2296638A1 (en) * | 1975-01-06 | 1976-07-30 | Inst Organicheskogo Sinteza Ak | PROCESS FOR PREPARING 6-B-AMIDINOPENICILLANIC ACID DERIVATIVES |
Also Published As
Publication number | Publication date |
---|---|
JPS518955B1 (en) | 1976-03-22 |
IT1044209B (en) | 1980-03-20 |
AT301026B (en) | 1972-08-25 |
SE397355B (en) | 1977-10-31 |
FR2073338B1 (en) | 1974-02-15 |
DE2055531B2 (en) | 1980-01-10 |
NO137826C (en) | 1982-02-16 |
NL168227B (en) | 1981-10-16 |
ES385437A1 (en) | 1973-11-01 |
NL168227C (en) | 1982-03-16 |
FI54601B (en) | 1978-09-29 |
NL7016435A (en) | 1971-05-13 |
IL35490A (en) | 1974-11-29 |
BE758782A (en) | 1971-05-10 |
IE34620B1 (en) | 1975-06-25 |
CH559753A5 (en) | 1975-03-14 |
DK135127C (en) | 1977-08-15 |
FI54601C (en) | 1979-01-10 |
CS166020B2 (en) | 1976-01-29 |
RO56878A (en) | 1975-02-15 |
LU62031A1 (en) | 1971-05-10 |
CH559752A5 (en) | 1975-03-14 |
NO137826B (en) | 1978-01-23 |
IE34620L (en) | 1971-05-11 |
DE2055531C3 (en) | 1982-02-25 |
PL90581B1 (en) | 1977-01-31 |
DE2055531A1 (en) | 1971-05-27 |
RO60563A (en) | 1977-01-15 |
BG18619A3 (en) | 1975-02-25 |
SU406362A3 (en) | 1973-11-05 |
HU162440B (en) | 1973-02-28 |
IL35490A0 (en) | 1970-12-24 |
DK135127B (en) | 1977-03-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TP | Transmission of property | ||
CC | Supplementary protection certificate (spc) laid open to the public (law of 25 june 1990) |
Free format text: 92C0027, 920225 |
|
CB | Supplementary protection certificate (spc) granted (law of 25 june 1990) |
Free format text: 92C0027, 701110 |
|
CP | Supplementary protection certificate (spc) filed |