FR19C1042I1 - - Google Patents

Info

Publication number
FR19C1042I1
FR19C1042I1 FR19C1042C FR19C1042I1 FR 19C1042 I1 FR19C1042 I1 FR 19C1042I1 FR 19C1042 C FR19C1042 C FR 19C1042C FR 19C1042 I1 FR19C1042 I1 FR 19C1042I1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
Other languages
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of FR19C1042I1 publication Critical patent/FR19C1042I1/fr
Application granted granted Critical
Publication of FR19C1042I2 publication Critical patent/FR19C1042I2/fr
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR19C1042C 2005-05-25 2019-06-20 Derive de morphinane substitue par un carbamoyle en position 7 et ayant une insauration en position 6,7 Active FR19C1042I2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2005151864 2005-05-25
JP2006065762 2006-03-10
PCT/JP2006/310231 WO2006126529A1 (ja) 2005-05-25 2006-05-23 ６，７－不飽和－７－カルバモイル置換モルヒナン誘導体
PCT/JP2006/310454 WO2006126637A1 (ja) 2005-05-25 2006-05-25 ６，７－不飽和－７－カルバモイル置換モルヒナン誘導体

Publications (2)

Publication Number Publication Date
FR19C1042I1 true FR19C1042I1 (ko) 2019-08-09
FR19C1042I2 FR19C1042I2 (fr) 2020-06-19

Family

ID=37451954

Family Applications (1)

Application Number Title Priority Date Filing Date
FR19C1042C Active FR19C1042I2 (fr) 2005-05-25 2019-06-20 Derive de morphinane substitue par un carbamoyle en position 7 et ayant une insauration en position 6,7

Country Status (19)

Country Link
US (4) USRE46365E1 (ko)
EP (1) EP1889848B8 (ko)
JP (1) JP4323547B2 (ko)
KR (1) KR100912782B1 (ko)
CN (1) CN101228172B (ko)
AU (1) AU2006250390B2 (ko)
BR (1) BRPI0610343B8 (ko)
CA (1) CA2609733C (ko)
DK (1) DK1889848T3 (ko)
ES (1) ES2525215T3 (ko)
FR (1) FR19C1042I2 (ko)
HU (1) HUS1900034I1 (ko)
MX (1) MX2007014588A (ko)
NL (1) NL300996I2 (ko)
PL (1) PL1889848T3 (ko)
PT (1) PT1889848E (ko)
RU (1) RU2403255C2 (ko)
TW (1) TWI311056B (ko)
WO (2) WO2006126529A1 (ko)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006126529A1 (ja) 2005-05-25 2006-11-30 Shionogi & Co., Ltd. ６，７－不飽和－７－カルバモイル置換モルヒナン誘導体
US10512644B2 (en) 2007-03-12 2019-12-24 Inheris Pharmaceuticals, Inc. Oligomer-opioid agonist conjugates
US8173666B2 (en) 2007-03-12 2012-05-08 Nektar Therapeutics Oligomer-opioid agonist conjugates
ES2620672T3 (es) * 2008-01-09 2017-06-29 Charleston Laboratories, Inc. Comprimidos de doble capa que comprenden oxicodona y prometazina
JP5252391B2 (ja) * 2008-02-21 2013-07-31 学校法人北里研究所 オキサビシクロ［２．２．２］オクタンを有するモルヒナン誘導体およびその医薬用途
US20110237614A1 (en) * 2008-09-16 2011-09-29 Nektar Therapeutics Pegylated Opioids with Low Potential for Abuse
MX342548B (es) * 2009-09-18 2016-10-04 Merck Sharp & Dohme Corp * Uso del antagonista del receptor opiaceo para los trastornos del tracto gastrointestinal.
US20130217672A1 (en) * 2010-05-13 2013-08-22 Green Cross Corporation (+)-3-hydroxymorphinan-based polycycle derivatives
BR112013011593B1 (pt) * 2010-11-12 2022-02-22 Shionogi & Co., Ltd Sal de ácido p-toluenossulfônico
DK2851075T3 (da) 2012-05-14 2022-01-31 Shionogi & Co Præparat, der indeholder 6,7-umættet -7-carbamoylmorphinanderivat
US11135217B2 (en) 2016-12-26 2021-10-05 Shionogi & Co., Ltd. Manufacturing process of formulation having improved content uniformity
MA52249A (fr) 2018-04-12 2021-05-05 Morphic Therapeutic Inc Antagonistes de l'intégrine humaine (alpha4) (beta7)
KR102201609B1 (ko) * 2019-04-19 2021-01-12 연성정밀화학(주) 날데메딘의 제조방법
WO2021076902A1 (en) 2019-10-16 2021-04-22 Morphic Therapeutic, Inc. INHIBITING HUMAN INTEGRIN α 4 β 7
JPWO2021100728A1 (ko) 2019-11-20 2021-05-27
CN111905111B (zh) * 2020-09-16 2023-03-31 地奥集团成都药业股份有限公司 一种评价复方谷氨酰胺组方对腹泻型肠易激综合征疗效的方法

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4272541A (en) 1978-06-02 1981-06-09 Miles Laboratories, Inc. 7,8 and 7-8 Substituted 4,5α-epoxymorphinan-6-one compounds, and methods of treating pain and drug dependence with them
US4275205A (en) 1980-05-05 1981-06-23 Miles Laboratories, Inc. 7,7-Ditosyloxymethyl-4,5α-epoxy-morphinan-6-ols
US4347361A (en) 1980-12-10 1982-08-31 Sisa, Incorporated 4,5α-Epoxy-3-hydroxy or methoxy-7-(1-hydroxy-alkyl or 1-oxoalkyl)morphinan-6-one compounds
US4370333A (en) 1981-06-29 1983-01-25 Sisa, Incorporated 17-Cyclopropylmethyl-3-hydroxy-14-methoxy 7α-methyl-morphinan-6-one and therapeutic method of treating pain with it
US4443605A (en) 1982-07-30 1984-04-17 Miles Laboratories, Inc. 7β-Arylalkyl-6α, 7 α-oxymethylene-3-methoxy or 3-hydroxy-4, 5α-epoxy-17 methyl or 17-cycloalkyl-methyl morphinans
US4440932A (en) 1982-09-09 1984-04-03 Miles Laboratories, Inc. 7β-Arylalkyl-7α-methyl-6-oxo or 6α-hydroxy-3-methoxy or 3-hydroxy-4,5α-epoxy-17-methyl or 17-cycloalkyl-methylmorphinans
AU686203B2 (en) 1993-07-23 1998-02-05 Toray Industries, Inc. Morphinan derivative and medicinal use
US5464841A (en) 1993-11-08 1995-11-07 Univ Minnesota Use of delta opioid receptor antagonists to treat immunoregulatory disorders
IL125226A0 (en) 1996-01-10 1999-03-12 Smithkline Beecham Spa Heterocycle-condensed morphinoid derivatives (II)
WO2001002375A1 (en) 1999-07-01 2001-01-11 Chemrx Advanced Technologies, Inc. Process for synthesizing oxadiazoles
IL149600A0 (en) * 1999-11-29 2002-11-10 Adolor Corp Novel methods and compositions involving opioids and antagonists thereof
AU5945801A (en) 2000-05-05 2001-11-20 Pain Therapeutics Inc Opoid antagonist compositions and dosage forms
US20040024004A1 (en) 2001-05-04 2004-02-05 Sherman Barry M. Novel compositions and methods for enhancing potency or reducing adverse side effects of opioid agonists
AU2001259458B2 (en) 2000-05-05 2006-09-14 Albert Einstein College Of Medicine Of Yeshiva University Opioid antagonist compositions and dosage forms
WO2002036573A2 (en) * 2000-10-31 2002-05-10 Rensselaer Polytechnic Institute 8- substituted-2, 6-methano-3-benzazocines and 3-substituted morphinanes as opioid receptor binding agents
DE60135016D1 (de) * 2000-11-22 2008-09-04 Toray Industries Indolderivate und deren verwendung in medikamenten
DE10161963A1 (de) 2001-12-17 2003-07-03 Johannes Schuetz 6-Aminomorphinanderivate, Herstellungsverfahren dafür und deren Verwendung
DE10229842A1 (de) * 2002-07-03 2004-02-05 Helmut Prof. Dr. Schmidhammer Morphinanderivate und deren quartäre Ammoniumsalze substituiert in Position 14, Herstellungsverfahren und Verwendung
EP1522542A1 (en) 2002-07-11 2005-04-13 Toray Industries, Inc. Therapeutic or preventive agent for nausea/vomiting
AU2003299045A1 (en) 2002-09-18 2004-04-08 The Curators Of The University Of Missouri OPIATE ANALOGS SELECTIVE FOR THE delta-OPIOID RECEPTOR
US20040157784A1 (en) 2003-02-10 2004-08-12 Jame Fine Chemicals, Inc. Opiod tannate compositions
WO2005105093A2 (en) 2003-08-26 2005-11-10 Duke University METHOD OF ARRESTING THE SIDE EFFECTS OF µ-OPIOID RECEPTOR AGONISTS DURING THEIR ADMINISTRATION
WO2005117589A1 (en) 2004-05-28 2005-12-15 Human Biomolecular Research Institute Synthesis of metabolically stable analgesics, pain medications and other agents
US20060063792A1 (en) 2004-09-17 2006-03-23 Adolor Corporation Substituted morphinans and methods of their use
US7142420B2 (en) 2004-09-20 2006-11-28 Qualcomm, Incorporated Devices and methods for controlling relative movement between layers of an electronic device
WO2006126529A1 (ja) 2005-05-25 2006-11-30 Shionogi & Co., Ltd. ６，７－不飽和－７－カルバモイル置換モルヒナン誘導体
BR112013011593B1 (pt) 2010-11-12 2022-02-22 Shionogi & Co., Ltd Sal de ácido p-toluenossulfônico

Also Published As

Publication number Publication date
KR20080014791A (ko) 2008-02-14
US8536192B2 (en) 2013-09-17
DK1889848T3 (en) 2014-12-01
PT1889848E (pt) 2014-12-09
PL1889848T3 (pl) 2015-04-30
BRPI0610343A2 (pt) 2010-06-15
HUS1900034I1 (hu) 2019-07-29
USRE46365E1 (en) 2017-04-11
EP1889848B1 (en) 2014-10-15
CN101228172A (zh) 2008-07-23
ES2525215T3 (es) 2014-12-19
US8084460B2 (en) 2011-12-27
RU2007148412A (ru) 2009-06-27
TW200726470A (en) 2007-07-16
EP1889848A1 (en) 2008-02-20
AU2006250390B2 (en) 2010-07-08
WO2006126637A1 (ja) 2006-11-30
NL300996I2 (nl) 2019-07-30
WO2006126529A1 (ja) 2006-11-30
EP1889848A4 (en) 2011-08-10
BRPI0610343B1 (pt) 2020-03-10
FR19C1042I2 (fr) 2020-06-19
NL300996I1 (nl) 2019-07-03
MX2007014588A (es) 2008-01-24
KR100912782B1 (ko) 2009-08-18
CA2609733C (en) 2011-07-19
RU2403255C2 (ru) 2010-11-10
EP1889848B8 (en) 2014-12-17
JPWO2006126637A1 (ja) 2008-12-25
AU2006250390A1 (en) 2006-11-30
USRE46375E1 (en) 2017-04-25
US20120135978A1 (en) 2012-05-31
JP4323547B2 (ja) 2009-09-02
TWI311056B (en) 2009-06-21
CN101228172B (zh) 2013-04-03
CA2609733A1 (en) 2006-11-30
US20090203723A1 (en) 2009-08-13
BRPI0610343B8 (pt) 2021-05-25

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