FI973085A0 - Menetelmä 1-(tiometyyli)syklopropaanietikkahapon valmistamiseksi - Google Patents
Menetelmä 1-(tiometyyli)syklopropaanietikkahapon valmistamiseksiInfo
- Publication number
- FI973085A0 FI973085A0 FI973085A FI973085A FI973085A0 FI 973085 A0 FI973085 A0 FI 973085A0 FI 973085 A FI973085 A FI 973085A FI 973085 A FI973085 A FI 973085A FI 973085 A0 FI973085 A0 FI 973085A0
- Authority
- FI
- Finland
- Prior art keywords
- thiomethyl
- preparation
- cyclopropaneacetic acid
- cyclopropaneacetic
- acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/20—Esters of monothiocarboxylic acids
- C07C327/32—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/16—Preparation of carboxylic acid nitriles by reaction of cyanides with lactones or compounds containing hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/02—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
- C07D327/10—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms two oxygen atoms and one sulfur atom, e.g. cyclic sulfates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/376,715 US5523477A (en) | 1995-01-23 | 1995-01-23 | Process for the preparation of 1-(thiomethyl)-cyclopropaneacetic acid |
PCT/US1996/000625 WO1996022987A1 (en) | 1995-01-23 | 1996-01-19 | Process for the preparation of 1-(thiomethyl)-cyclopropaneacetic acid |
Publications (2)
Publication Number | Publication Date |
---|---|
FI973085A0 true FI973085A0 (fi) | 1997-07-22 |
FI973085A FI973085A (fi) | 1997-07-22 |
Family
ID=23486169
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI973085A FI973085A (fi) | 1995-01-23 | 1997-07-22 | Menetelmä 1-(tiometyyli)syklopropaanietikkahapon valmistamiseksi |
Country Status (16)
Country | Link |
---|---|
US (1) | US5523477A (fi) |
EP (1) | EP0805808A1 (fi) |
CN (1) | CN1072218C (fi) |
AR (1) | AR000772A1 (fi) |
AU (1) | AU4657396A (fi) |
BR (1) | BR9607083A (fi) |
CZ (1) | CZ234897A3 (fi) |
EA (2) | EA000090B1 (fi) |
FI (1) | FI973085A (fi) |
HR (1) | HRP960028A2 (fi) |
RO (1) | RO118131B1 (fi) |
SK (1) | SK99897A3 (fi) |
TW (1) | TW322475B (fi) |
UA (1) | UA50730C2 (fi) |
WO (1) | WO1996022987A1 (fi) |
YU (1) | YU3596A (fi) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5904068A (en) | 1996-04-30 | 1999-05-18 | Eaton Corporation | Semi-automatic shift implementation with synchronized transmission emulation |
CA2371048C (en) | 2002-02-06 | 2011-01-04 | Delmar Chemicals Inc. | Process for the preparation of 1-(mercaptomethyl)-cyclopropaneacetic acid |
CN1318400C (zh) * | 2002-02-06 | 2007-05-30 | 戴尔玛化学品股份有限公司 | 制备1-(巯基甲基)-环丙烷乙酸的方法 |
US7560559B2 (en) * | 2003-04-15 | 2009-07-14 | Merck & Co., Inc. | Polymorphic form of montelukast sodium |
EP1678139B1 (en) * | 2003-10-10 | 2011-08-31 | Synhton B.V. | Solid-state montelukast |
US20050187243A1 (en) * | 2004-01-30 | 2005-08-25 | Valerie Niddam-Hildesheim | Montelukast free acid polymorphs |
EP1760077A1 (en) * | 2004-01-30 | 2007-03-07 | Teva Pharmaceutical Industries Ltd. | Montelukast free acid polymorphs |
WO2005075427A2 (en) * | 2004-01-30 | 2005-08-18 | Teva Pharmaceutical Industries Ltd. | Montelukast sodium polymorphs |
MXPA06012220A (es) * | 2004-04-21 | 2007-07-18 | Teva Pharma | Procesos para preparar sodio de montelukast. |
US7501517B2 (en) * | 2004-04-30 | 2009-03-10 | Synthon Ip, Inc. | Process for making montelukast and intermediates therefor |
US7829716B2 (en) * | 2004-04-30 | 2010-11-09 | Synthon Pharmaceuticals, Inc. | Process for making montelukast and intermediates therefor |
US20090143590A1 (en) * | 2004-07-19 | 2009-06-04 | Matrix Laboratories Ltd. | Process for the Preparation of Montelukast and its Salts |
US7812168B2 (en) * | 2005-07-05 | 2010-10-12 | Teva Pharmaceutical Industries Ltd. | Purification of montelukast |
EP1912499A4 (en) * | 2005-07-20 | 2010-03-31 | Reddys Lab Ltd Dr | PREPARATION OF MONTELUKAST |
US20070161796A1 (en) * | 2005-11-16 | 2007-07-12 | Ilan Kor-Sade | Drying methods of montelukast sodium by azeotropic removal of the solvent |
AR057908A1 (es) * | 2005-11-18 | 2007-12-26 | Synthon Bv | Proceso para preparar montelukast e intermediarios del mismo |
CA2643228A1 (en) * | 2006-02-21 | 2007-08-30 | Chemagis Ltd. | Novel polymorphs of montelukast ammonium salts and processes for preparation therefor |
WO2007096889A2 (en) * | 2006-02-27 | 2007-08-30 | Chemagis Ltd. | Process for preparing montelukast and salts thereof |
EP1996552A1 (en) * | 2006-03-17 | 2008-12-03 | Synthon B.V. | Montelukast amantadine salt |
WO2008001213A1 (en) * | 2006-06-26 | 2008-01-03 | Aurobindo Pharma Limited | An improved process for the preparation of leukotriene receptor antagonist (montelukast sodium) |
GB0618703D0 (en) * | 2006-09-22 | 2006-11-01 | Almac Sciences Ltd | Synthesis of leikotriene compounds |
US7700776B2 (en) * | 2006-10-24 | 2010-04-20 | Formosa Laboratories, Inc. | Compounds and preparation for montelukast sodium |
US7271268B1 (en) | 2006-12-22 | 2007-09-18 | Formosa Laboratories Inc. | Process for preparation of [1-(mercaptomethyl)cyclopropyl]acetic acid and related derivatives |
US20080188664A1 (en) * | 2007-01-15 | 2008-08-07 | Chemagis Ltd. | Process for preparing montelukast sodium containing controlled levels of impurities |
KR101072896B1 (ko) | 2007-10-09 | 2011-10-17 | 한미홀딩스 주식회사 | 이온성 액체 매개체를 이용한 몬테루카스트산의 제조 방법 |
EP2276739A1 (en) * | 2008-04-25 | 2011-01-26 | Synthon B.V. | Process for making montelukast intermediates |
ES2605473T3 (es) * | 2008-05-26 | 2017-03-14 | Laurus Labs Private Limited | Un procedimiento mejorado para la preparación de Montelukast y sus sales |
CN101880270B (zh) * | 2009-05-07 | 2012-10-03 | 上海华升生物科技有限公司 | 一种制备1,1-环丙烷二甲醇环亚硫酸酯的方法 |
WO2011004298A1 (en) | 2009-07-09 | 2011-01-13 | Alembic Limited | Montelukast hexamethylenediamine salt and its use for the preparation of montelukast sodium |
US8471030B2 (en) | 2010-12-06 | 2013-06-25 | Orochem Technologies Inc. | Purification of montelukast using simulated moving bed |
KR101431678B1 (ko) | 2012-01-10 | 2014-08-22 | (주)위즈켐 | 1-(1'-(카복시메틸)시클로프로판메틸디설파닐메틸)시클로프로판아세트산과 그 유도체의 제조방법 |
CN103058884B (zh) * | 2012-12-14 | 2014-10-29 | 武汉赛狮药物化学有限公司 | 1-羟甲基环丙基乙腈的合成方法 |
CN111170939A (zh) * | 2019-12-20 | 2020-05-19 | 牡丹江恒远药业股份有限公司 | 一种高纯度孟鲁司特钠及其中间体的制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0172371A1 (de) * | 1984-07-27 | 1986-02-26 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Verfahren zur Herstellung von Dehydroxypantolacton |
EP0480717B1 (en) * | 1990-10-12 | 1998-04-15 | Merck Frosst Canada Inc. | Unsaturated hydroxyalkylquinoline acids as leukotriene antagonists |
US5270324A (en) * | 1992-04-10 | 1993-12-14 | Merck Frosst Canada, Inc. | Fluorinated hydroxyalkylquinoline acids as leukotriene antagonists |
CA2111372C (en) * | 1992-12-22 | 2007-01-16 | Robert N. Young | Diaryl 5,6-fusedheterocyclic acids as leukotriene antagonists |
US5438141A (en) * | 1993-05-21 | 1995-08-01 | Merck Frosst Canada, Inc. | Heteroaryl and haloaryl quinoline derivatives of cyclopropaneacetic acid as leukotriene antagonists |
US5350760A (en) * | 1993-08-04 | 1994-09-27 | Merck Frosst Canada, Inc. | Aza-5,5-fused hetrocyclic acids as leukotriene antagonists |
TW448160B (en) * | 1993-12-28 | 2001-08-01 | Merck & Co Inc | Novel dicyclohexylamine salt and process for the preparation of leukotriene antagonists |
-
1995
- 1995-01-23 US US08/376,715 patent/US5523477A/en not_active Expired - Lifetime
-
1996
- 1996-01-17 TW TW085100534A patent/TW322475B/zh active
- 1996-01-19 RO RO97-01353A patent/RO118131B1/ro unknown
- 1996-01-19 SK SK998-97A patent/SK99897A3/sk unknown
- 1996-01-19 AU AU46573/96A patent/AU4657396A/en not_active Abandoned
- 1996-01-19 WO PCT/US1996/000625 patent/WO1996022987A1/en not_active Application Discontinuation
- 1996-01-19 UA UA97084349A patent/UA50730C2/uk unknown
- 1996-01-19 EP EP96902152A patent/EP0805808A1/en not_active Withdrawn
- 1996-01-19 EA EA199700137A patent/EA000090B1/ru not_active IP Right Cessation
- 1996-01-19 CN CN96191576A patent/CN1072218C/zh not_active Expired - Fee Related
- 1996-01-19 CZ CZ972348A patent/CZ234897A3/cs unknown
- 1996-01-19 BR BR9607083A patent/BR9607083A/pt not_active Application Discontinuation
- 1996-01-22 YU YU3596A patent/YU3596A/sh unknown
- 1996-01-22 HR HR08/376,715A patent/HRP960028A2/hr not_active Application Discontinuation
- 1996-01-22 AR ARP960101101A patent/AR000772A1/es active IP Right Grant
-
1997
- 1997-07-22 FI FI973085A patent/FI973085A/fi unknown
- 1997-08-22 EA EA199700137D patent/EA199700137A1/ru unknown
Also Published As
Publication number | Publication date |
---|---|
AR000772A1 (es) | 1997-08-06 |
CZ234897A3 (cs) | 1998-02-18 |
AU4657396A (en) | 1996-08-14 |
UA50730C2 (uk) | 2002-11-15 |
YU3596A (sh) | 1998-07-10 |
HRP960028A2 (en) | 1997-10-31 |
EP0805808A1 (en) | 1997-11-12 |
CN1072218C (zh) | 2001-10-03 |
EA199700137A1 (ru) | 1997-12-30 |
US5523477A (en) | 1996-06-04 |
FI973085A (fi) | 1997-07-22 |
CN1172481A (zh) | 1998-02-04 |
BR9607083A (pt) | 1997-11-11 |
WO1996022987A1 (en) | 1996-08-01 |
EA000090B1 (ru) | 1998-06-25 |
RO118131B1 (ro) | 2003-02-28 |
TW322475B (fi) | 1997-12-11 |
SK99897A3 (en) | 1998-04-08 |
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