FI962114A0 - Yhdistelmä-DNA-adenoviruksia syöpien geeniterapiaan - Google Patents
Yhdistelmä-DNA-adenoviruksia syöpien geeniterapiaanInfo
- Publication number
- FI962114A0 FI962114A0 FI962114A FI962114A FI962114A0 FI 962114 A0 FI962114 A0 FI 962114A0 FI 962114 A FI962114 A FI 962114A FI 962114 A FI962114 A FI 962114A FI 962114 A0 FI962114 A0 FI 962114A0
- Authority
- FI
- Finland
- Prior art keywords
- cancers
- gene therapy
- recombinant adenovirus
- adenovirus
- recombinant
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/10—Plasmid DNA
- C12N2800/108—Plasmid DNA episomal vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
- C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/15—Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/60—Vector systems having a special element relevant for transcription from viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9313766A FR2712602B1 (fr) | 1993-11-18 | 1993-11-18 | Virus recombinants, préparation et utilisation en thérapie génique. |
PCT/FR1994/001284 WO1995014101A1 (fr) | 1993-11-18 | 1994-11-07 | Adenovirus recombinants pour la therapie genique des cancers |
Publications (2)
Publication Number | Publication Date |
---|---|
FI962114A FI962114A (fi) | 1996-05-17 |
FI962114A0 true FI962114A0 (fi) | 1996-05-17 |
Family
ID=9452970
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI962114A FI962114A0 (fi) | 1993-11-18 | 1996-05-17 | Yhdistelmä-DNA-adenoviruksia syöpien geeniterapiaan |
Country Status (12)
Country | Link |
---|---|
US (2) | US5837531A (no) |
EP (1) | EP0729516A1 (no) |
JP (1) | JPH09504955A (no) |
KR (1) | KR100368292B1 (no) |
AU (1) | AU699867B2 (no) |
CA (1) | CA2176585A1 (no) |
FI (1) | FI962114A0 (no) |
FR (1) | FR2712602B1 (no) |
IL (1) | IL111682A0 (no) |
NO (1) | NO317725B1 (no) |
WO (1) | WO1995014101A1 (no) |
ZA (1) | ZA949103B (no) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5747469A (en) | 1991-03-06 | 1998-05-05 | Board Of Regents, The University Of Texas System | Methods and compositions comprising DNA damaging agents and p53 |
EP0575518A1 (en) | 1991-03-06 | 1993-12-29 | Board Of Regents, The University Of Texas System | Methods and compositions for the selective inhibition of gene expression |
US6410010B1 (en) | 1992-10-13 | 2002-06-25 | Board Of Regents, The University Of Texas System | Recombinant P53 adenovirus compositions |
ATE211174T1 (de) * | 1994-05-02 | 2002-01-15 | Univ Washington | Thymidin-kinase-mutanten |
AU711269B2 (en) | 1994-08-16 | 1999-10-07 | Crucell Holland B.V. | Recombinant vectors derived from adenovirus for use in gene therapy |
DE19608751B4 (de) | 1996-03-06 | 2006-05-18 | Medigene Ag | Verwendung eines Adeno-assoziierten Virus-Vektors zur Steigerung der Immunogenität von Zellen |
US7001765B2 (en) | 1996-03-06 | 2006-02-21 | Medigene Ag | Adeno-associated virus vector for boosting immunogenicity of cells |
US6054467A (en) * | 1996-07-05 | 2000-04-25 | Sidney Kimmel Cancer Center | Down-regulation of DNA repair to enhance sensitivity to P53-mediated apoptosis |
US5958892A (en) | 1996-07-30 | 1999-09-28 | Board Of Regents, The University Of Texas System | 2-methoxyestradiol-induced apoptosis in cancer cells |
US7041654B2 (en) | 1997-10-03 | 2006-05-09 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Methods and compositions for inducing tumor-specific cytotoxicity |
WO1999041371A1 (en) | 1998-02-13 | 1999-08-19 | Genetrace Systems, Inc. | Use of ribozymes for functionating genes |
CN1405312A (zh) * | 2001-01-18 | 2003-03-26 | 中山卫健生物科技有限公司 | 一种能特异性杀灭eb病毒相关肿瘤的重组病毒及其构建方法 |
AU2002351568A1 (en) * | 2001-12-06 | 2003-06-17 | University Health Network | Nucleic acids and methods for treating ebv-positive cancers |
US20040052161A1 (en) * | 2002-09-17 | 2004-03-18 | Steven Liao | Mechanical clock having wireless manipulation and adjustment function |
AU2003286729A1 (en) * | 2002-10-25 | 2004-05-13 | University Of Massachusetts | Modulation of cellular proliferation |
US7442830B1 (en) | 2007-08-06 | 2008-10-28 | Millenium Pharmaceuticals, Inc. | Proteasome inhibitors |
EP2730579A1 (en) | 2008-06-17 | 2014-05-14 | Millennium Pharmaceuticals, Inc. | Boronate ester compounds and pharmaceutical compositions thereof |
KR102481856B1 (ko) | 2014-05-20 | 2022-12-26 | 밀레니엄 파머슈티컬스 인코퍼레이티드 | 일차 암 치료법 후 사용하기 위한 붕소-함유 프로테아좀 저해제 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4939088A (en) * | 1987-02-18 | 1990-07-03 | Meloy Laboratories Inc. | Sustained production of recombinant gamma interferon using an Epstein-Barr virus replicon |
US5672344A (en) | 1987-12-30 | 1997-09-30 | The Regents Of The University Of Michigan | Viral-mediated gene transfer system |
GB8919607D0 (en) * | 1989-08-30 | 1989-10-11 | Wellcome Found | Novel entities for cancer therapy |
US5194601A (en) * | 1989-09-18 | 1993-03-16 | Wisconsin Alumni Research Foundation | Lytic origin of replication for Epstein-Barr virus (EBV) |
NO312681B1 (no) * | 1990-08-24 | 2002-06-17 | Univ California | Fremgangsmåte for fremstilling av en farmasöytisk blanding med suppresiv virkning/aktivitet |
ATE129746T1 (de) * | 1990-09-14 | 1995-11-15 | Univ Johns Hopkins | Verfahren und zusammensetzungen für gentherapie und stärkung des immunsystems. |
FR2688514A1 (fr) * | 1992-03-16 | 1993-09-17 | Centre Nat Rech Scient | Adenovirus recombinants defectifs exprimant des cytokines et medicaments antitumoraux les contenant. |
US5631236A (en) * | 1993-08-26 | 1997-05-20 | Baylor College Of Medicine | Gene therapy for solid tumors, using a DNA sequence encoding HSV-Tk or VZV-Tk |
-
1993
- 1993-11-18 FR FR9313766A patent/FR2712602B1/fr not_active Expired - Fee Related
-
1994
- 1994-11-07 JP JP7514247A patent/JPH09504955A/ja active Pending
- 1994-11-07 US US08/646,246 patent/US5837531A/en not_active Ceased
- 1994-11-07 CA CA002176585A patent/CA2176585A1/fr not_active Abandoned
- 1994-11-07 WO PCT/FR1994/001284 patent/WO1995014101A1/fr not_active Application Discontinuation
- 1994-11-07 EP EP95900795A patent/EP0729516A1/fr not_active Withdrawn
- 1994-11-07 AU AU81471/94A patent/AU699867B2/en not_active Ceased
- 1994-11-07 KR KR1019960702622A patent/KR100368292B1/ko not_active IP Right Cessation
- 1994-11-07 US US09/654,223 patent/USRE39078E1/en not_active Expired - Fee Related
- 1994-11-16 ZA ZA949103A patent/ZA949103B/xx unknown
- 1994-11-17 IL IL11168294A patent/IL111682A0/xx unknown
-
1996
- 1996-05-14 NO NO19961977A patent/NO317725B1/no not_active IP Right Cessation
- 1996-05-17 FI FI962114A patent/FI962114A0/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
USRE39078E1 (en) | 2006-04-25 |
NO961977D0 (no) | 1996-05-14 |
US5837531A (en) | 1998-11-17 |
NO961977L (no) | 1996-05-14 |
ZA949103B (en) | 1995-07-21 |
CA2176585A1 (fr) | 1995-05-26 |
IL111682A0 (en) | 1995-01-24 |
JPH09504955A (ja) | 1997-05-20 |
AU699867B2 (en) | 1998-12-17 |
AU8147194A (en) | 1995-06-06 |
FR2712602A1 (fr) | 1995-05-24 |
EP0729516A1 (fr) | 1996-09-04 |
NO317725B1 (no) | 2004-12-13 |
KR100368292B1 (ko) | 2003-12-24 |
FR2712602B1 (fr) | 1996-02-09 |
FI962114A (fi) | 1996-05-17 |
WO1995014101A1 (fr) | 1995-05-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FI962114A0 (fi) | Yhdistelmä-DNA-adenoviruksia syöpien geeniterapiaan | |
FI940336A0 (fi) | Yhdistelmävasta-aineita ihmisterapiaan | |
FI970388A (fi) | Menetelmä kuvasekvenssien kontrastin parantamiseksi | |
GB9115909D0 (en) | Recombinant dna | |
IL111681A0 (en) | Recombinant viruses and their use in gene therapy | |
DE69625441D1 (de) | Reduzierte Viskositäten aufweisende aliphatisch silylierte Polyurethan-Mischungen | |
IT1291135B1 (it) | Vettori ricombinanti utilizzabili in terapia genica | |
FI961666A0 (fi) | Restenosiksen geeniterapia, jossa käytetään adenovirusvektoria | |
HUP9902150A3 (en) | Recombinant adenoviral vectors for human tumour gene therapy | |
DE69230825D1 (de) | Genexpression in bazillen | |
IT1267423B1 (it) | Apparecchio di carica | |
DE69307204D1 (de) | Tragbares motorisiertes Schleifgerät | |
DE69429650D1 (de) | Neues antitumor-peptid | |
KR970056943U (ko) | 약제 분쇄기 | |
CS175691A3 (en) | Recombinant dna | |
ZA945843B (en) | Recombinant adenovirus vaccines | |
KR950005771U (ko) | 곡물 분쇄기 | |
GB9912925D0 (en) | Adenoviral vectors encoding interferon and their use in gene therapy | |
BR7201779U (pt) | Disposicao introduzida em vestimenta refletiva | |
ITPS920044V0 (it) | Iperestensore articolato per terapie post-operatorie o per fisioterapie in genere | |
BR7200643U (pt) | Disposicao construtiva em caixa sifonada e similares | |
SI0889969T1 (sl) | Rekombinantni adenovirusni vektorji za gensko terapijo humanih tumorjev | |
BR9203311A (pt) | Aperfeicoamentos em carreta agricola graneleira | |
KR940000576U (ko) | 판넬 연마기 | |
KR940019090U (ko) | 다용도 분쇄기 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application lapsed |