FI962041A0 - Hemoglobiinin puhdistus - Google Patents

Hemoglobiinin puhdistus

Info

Publication number
FI962041A0
FI962041A0 FI962041A FI962041A FI962041A0 FI 962041 A0 FI962041 A0 FI 962041A0 FI 962041 A FI962041 A FI 962041A FI 962041 A FI962041 A FI 962041A FI 962041 A0 FI962041 A0 FI 962041A0
Authority
FI
Finland
Prior art keywords
hemoglobin
purification
Prior art date
Application number
FI962041A
Other languages
English (en)
Swedish (sv)
Other versions
FI962041A (fi
Inventor
Erin E Milne
Maura Ann Matthews
David W Traylor
James R Ryland
Antony J Mathews
Justinian O Neway
Ulrich P Ernst
Original Assignee
Somatogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Somatogen Inc filed Critical Somatogen Inc
Publication of FI962041A0 publication Critical patent/FI962041A0/fi
Publication of FI962041A publication Critical patent/FI962041A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
FI962041A 1993-11-15 1996-05-14 Hemoglobiinin puhdistus FI962041A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/153,071 US5665869A (en) 1993-11-15 1993-11-15 Method for the rapid removal of protoporphyrin from protoporphyrin IX-containing solutions of hemoglobin
PCT/US1994/013034 WO1995014038A2 (en) 1993-11-15 1994-11-15 Purification of hemoglobin

Publications (2)

Publication Number Publication Date
FI962041A0 true FI962041A0 (fi) 1996-05-14
FI962041A FI962041A (fi) 1996-06-14

Family

ID=22545660

Family Applications (1)

Application Number Title Priority Date Filing Date
FI962041A FI962041A (fi) 1993-11-15 1996-05-14 Hemoglobiinin puhdistus

Country Status (8)

Country Link
US (1) US5665869A (fi)
EP (1) EP0729475A1 (fi)
JP (1) JPH09510953A (fi)
AU (1) AU700366B2 (fi)
CA (1) CA2176494C (fi)
FI (1) FI962041A (fi)
NO (1) NO961959L (fi)
WO (1) WO1995014038A2 (fi)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5955581A (en) * 1986-11-10 1999-09-21 Biopure Corporation Method for producing a stable polymerized hemoglobin blood-substitute
US5753616A (en) * 1986-11-10 1998-05-19 Biopure Corporation Method for producing a stable polymerized hemoglobin blood-substitute
US5844090A (en) * 1994-05-09 1998-12-01 Somatogen, Inc. Modified hemoglobin-like compounds
US5840851A (en) * 1993-07-23 1998-11-24 Plomer; J. Jeffrey Purification of hemoglobin
US6242417B1 (en) * 1994-03-08 2001-06-05 Somatogen, Inc. Stabilized compositions containing hemoglobin
US6150507A (en) * 1995-03-23 2000-11-21 Biopure Corporation Method for producing a purified hemoglobin product
US5741894A (en) * 1995-09-22 1998-04-21 Baxter International, Inc. Preparation of pharmaceutical grade hemoglobins by heat treatment in partially oxygenated form
DE69625981T2 (de) * 1995-10-13 2004-01-22 Ajinomoto Co., Inc. Verfahren zum Entfernen von Zellen aus Fermentationsbrühe
US6114505A (en) * 1995-10-23 2000-09-05 William Marsh Rice University Hemoglobin mutants that reduce heme loss
US6812207B1 (en) 1995-10-23 2004-11-02 William Marsh Rice University Hemoglobin mutants that reduce heme loss
CA2236794A1 (en) * 1995-11-30 1997-06-05 Bruce A. Kerwin Method for control of functionality during cross-linking of hemoglobins
WO1997023631A2 (en) * 1995-12-22 1997-07-03 Somatogen, Inc. Globins containing binding domains
EP0868521A2 (en) 1995-12-22 1998-10-07 Somatogen Inc. Globins containing binding domains
AU2326297A (en) * 1996-03-06 1997-09-22 I. Belloch Corporation Method for treating liquid materials
JP2000516455A (ja) 1996-08-02 2000-12-12 バクスター バイオテック テクノロジー エス．アー．エール．エル． ヘモグロビンにおけるβダイマー形成を制御する方法
EP0960130A4 (en) 1996-09-27 2001-01-31 Trustees For The Board Of OXYGEN-BINDING HEMPROTEINS, WHICH CONTAIN THE CIRCULAR PERMUTED GLOBINE
EP0954586A1 (en) * 1996-10-18 1999-11-10 Baxter Biotech Technology S.A.R.L. Methods of reducing the levels of protoporphyrin ix in recombinant hemoglobin preparations
EP1950298A3 (en) 1997-05-02 2008-12-24 Baxter Biotech Technology S.A.R.L. Hemoglobin mutants with increased soluble expression and/or reduced nitric oxide scavenging
JP4512673B2 (ja) 1997-05-02 2010-07-28 バクスター バイオテク テクノロジー エス． アー． アール． エル． 増大した可溶性発現および／または低下した一酸化窒素の排出を伴うヘモグロビン変異体
AU784195B2 (en) 1999-11-12 2006-02-16 Baxter Biotech Technology S.A.R.L. Reduced side-effect hemoglobin compositions
US20080310995A1 (en) * 2003-12-12 2008-12-18 Charm Stanley E Method, Device and System for Thermal Processing
PT2079472E (pt) 2006-10-04 2011-11-24 Infacare Pharmaceutical Corp Preparação em larga escala de estansoporfina de alta pureza
PT2691398T (pt) 2011-03-30 2017-01-02 Infacare Pharmaceutical Corp Métodos para sintetizar mesoporfirinas de metal
TWI626248B (zh) * 2016-12-09 2018-06-11 中華醫事科技大學 血紅素及肌紅素之分離方法
CN111936059A (zh) * 2018-03-27 2020-11-13 精密科学公司 稳定血红蛋白的方法和实施该方法的试剂
CN113647367B (zh) * 2021-08-16 2022-11-18 双工方程(武汉)科技发展有限公司 一种提升整仓模式下机械充氮防虫效率的方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2449885C3 (de) * 1974-10-21 1980-04-30 Biotest-Serum-Institut Gmbh, 6000 Frankfurt Verfahren zur Herstellung von chemisch modifizierten haltbaren Hämoglobinpräparaten sowie das nach diesem Verfahren hergestellte modifizierte Hämoglobinpräparat
DE2740053A1 (de) * 1977-09-06 1979-05-03 Klaus Prof Dr Med Gersonde Verwendung von allosterischen effektoren mit hilfe von lipidvesikeln ueber eine irreversible inkorporierung zwecks verbesserter o tief 2 -entladung des haemoglobins in erythrozyten
JPS6023084B2 (ja) * 1979-07-11 1985-06-05 味の素株式会社 代用血液
JPS5716815A (en) * 1980-07-02 1982-01-28 Ajinomoto Co Inc Oxygen transporting agent for artificial blood
US4831012A (en) * 1984-03-23 1989-05-16 Baxter International Inc. Purified hemoglobin solutions and method for making same
US4598064A (en) * 1984-06-27 1986-07-01 University Of Iowa Research Foundation Alpha-alpha cross-linked hemoglobins
EP0206448B1 (en) * 1985-06-19 1990-11-14 Ajinomoto Co., Inc. Hemoglobin combined with a poly(alkylene oxide)
CA1244349A (en) * 1985-06-26 1988-11-08 Jen-Chang Hsia Purification of hemoglobin and modified hemoglobin by affinity chromatography
US4975246A (en) * 1985-09-30 1990-12-04 Charm Stanley E High temperature, short time heating system and method of heating heat-sensitive material
US5084558A (en) * 1987-10-13 1992-01-28 Biopure Corporation Extra pure semi-synthetic blood substitute
JP2962731B2 (ja) * 1986-11-10 1999-10-12 バイオピュアー、コーポレーション 超純枠半合成代用血液
GB8711614D0 (en) * 1987-05-16 1987-06-24 Medical Res Council Proteins
US4861867A (en) * 1988-02-03 1989-08-29 Baxter International, Inc. Purified hemoglobin solutions and method for making same
US5169936A (en) * 1989-04-14 1992-12-08 Biogen, Inc. Protein purification on immobilized metal affinity resins effected by elution using a weak ligand
ES2093640T3 (es) * 1989-05-10 1997-01-01 Somatogen Inc Produccion de hemoglobina y sus analogos mediante bacterias y levadura.
US5173426A (en) * 1989-10-06 1992-12-22 Yale University DNAs encoding genetically engineered low oxygen affinity mutants of human hemoglobin
AU7744491A (en) * 1990-04-16 1991-11-11 Strohtech, Inc. Expression of recombinant hemoglobin in yeast
EP0668909B1 (en) * 1990-12-20 2001-10-10 The University Of Alabama Research Foundation Transgenic, cross-linked hemoglobin
CA2111348A1 (en) * 1991-06-14 1992-12-23 John S. Logan Production of human hemoglobin in transgenic pigs
WO1993008831A1 (en) * 1991-10-30 1993-05-13 Strohtech, Inc. Expression of recombinant hemoglobin and hemoglobin variants in yeast
WO1993008842A1 (en) * 1991-11-08 1993-05-13 Somatogen, Inc. Hemoglobins as drug delivery agents

Also Published As

Publication number Publication date
CA2176494C (en) 2000-08-22
NO961959L (no) 1996-06-18
WO1995014038A3 (en) 1995-08-03
EP0729475A1 (en) 1996-09-04
NO961959D0 (no) 1996-05-14
JPH09510953A (ja) 1997-11-04
CA2176494A1 (en) 1995-05-26
US5665869A (en) 1997-09-09
FI962041A (fi) 1996-06-14
AU1176795A (en) 1995-06-06
AU700366B2 (en) 1999-01-07
WO1995014038A2 (en) 1995-05-26

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Legal Events

Date Code Title Description
GB Transfer or assigment of application

Owner name: BAXTER BIOTECH TECHNOLOGY S.A.R.L.