FI955416A0 - MTS-geenin sukusolulinjan mutaatioita ja menetelmä syövälle altistumisen löytämiseksi MTS-geenistä - Google Patents

MTS-geenin sukusolulinjan mutaatioita ja menetelmä syövälle altistumisen löytämiseksi MTS-geenistä

Info

Publication number
FI955416A0
FI955416A0 FI955416A FI955416A FI955416A0 FI 955416 A0 FI955416 A0 FI 955416A0 FI 955416 A FI955416 A FI 955416A FI 955416 A FI955416 A FI 955416A FI 955416 A0 FI955416 A0 FI 955416A0
Authority
FI
Finland
Prior art keywords
mts gene
germ cell
detecting cancer
cell mutations
mts
Prior art date
Application number
FI955416A
Other languages
English (en)
Swedish (sv)
Other versions
FI955416A (fi
Inventor
Mark H Skolnick
Lisa A Cannon-Albright
Alexander Kamb
Original Assignee
Univ Utah Res Found
Myriad Genetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27539687&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI955416(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Utah Res Found, Myriad Genetics Inc filed Critical Univ Utah Res Found
Publication of FI955416A0 publication Critical patent/FI955416A0/fi
Publication of FI955416A publication Critical patent/FI955416A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/136Screening for pharmacological compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/172Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FI955416A 1994-03-18 1995-11-10 MTS-geenin sukusolulinjan mutaatioita ja menetelmä syövälle altistumisen löytämiseksi MTS-geenistä FI955416A (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US21508694A 1994-03-18 1994-03-18
US21458294A 1994-03-18 1994-03-18
US21508794A 1994-03-18 1994-03-18
US22736994A 1994-04-14 1994-04-14
US25193894A 1994-06-01 1994-06-01
PCT/US1995/003537 WO1995025813A1 (en) 1994-03-18 1995-03-17 Germline mutations in the mts gene and method for detecting predisposition to cancer at the mts gene

Publications (2)

Publication Number Publication Date
FI955416A0 true FI955416A0 (fi) 1995-11-10
FI955416A FI955416A (fi) 1996-01-09

Family

ID=27539687

Family Applications (1)

Application Number Title Priority Date Filing Date
FI955416A FI955416A (fi) 1994-03-18 1995-11-10 MTS-geenin sukusolulinjan mutaatioita ja menetelmä syövälle altistumisen löytämiseksi MTS-geenistä

Country Status (11)

Country Link
US (9) US5994095A (fi)
EP (1) EP0702730A4 (fi)
JP (1) JPH08510391A (fi)
CN (1) CN1128049A (fi)
AU (1) AU685627B2 (fi)
CA (1) CA2162150C (fi)
FI (1) FI955416A (fi)
NO (1) NO954495L (fi)
NZ (1) NZ284612A (fi)
RU (1) RU2161309C2 (fi)
WO (1) WO1995025813A1 (fi)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5962316A (en) * 1992-10-16 1999-10-05 Cold Spring Harbor Laboratory Cell-cycle regulatory proteins, and uses related thereto
US7691632B2 (en) * 1993-11-18 2010-04-06 Cold Spring Harbor Laboratory Kit for detecting the level of cyclin-dependent kinase inhibitor P16 gene expression
WO1995019369A1 (en) 1994-01-14 1995-07-20 Vanderbilt University Method for detection and treatment of breast cancer
US6060301A (en) * 1994-03-18 2000-05-09 Myriad Genetics, Inc. Vector containing MTS1E1β gene
RU2161309C2 (ru) * 1994-03-18 2000-12-27 Исследовательский Фонд Университета Юты, Мутации гена мтs в зародышевой линии и способ выявления предрасположенности к злокачественным опухолям в гене мтs
US6689864B1 (en) 1994-04-14 2004-02-10 The Regents Of The University Of California Cyclin dependent kinase 4 inhibitor
US5767258A (en) * 1995-05-12 1998-06-16 The Johns Hopkins University School Of Medicine Cell cycle regulatory gene
US7163925B1 (en) 1995-07-17 2007-01-16 Board Of Regents, The University Of Texas System p16 expression constructs and their application in cancer therapy
HUP9901908A3 (en) 1995-07-17 2000-02-28 Univ Texas P16 expression constructs and their application in cancer therapy
GB9519275D0 (en) * 1995-09-21 1995-11-22 Univ Dundee Substances and their therapeutic use
US6586203B1 (en) 1995-09-27 2003-07-01 St. Jude Children's Research Hospital ARF-P19, a novel regulator of the mammalian cell cycle
US5723313A (en) 1995-09-27 1998-03-03 St. Jude Children's Research Hospital ARF-p19, a novel regulator of the mammalian cell cycle
US6407062B1 (en) 1995-09-27 2002-06-18 St. Jude Children's Research Hospital ARF-P19, a novel regulator of the mammalian cell cycle
US5670325A (en) * 1996-08-14 1997-09-23 Exact Laboratories, Inc. Method for the detection of clonal populations of transformed cells in a genomically heterogeneous cellular sample
US5741650A (en) * 1996-01-30 1998-04-21 Exact Laboratories, Inc. Methods for detecting colon cancer from stool samples
US5891857A (en) * 1996-02-20 1999-04-06 Vanderbilt University Characterized BRCA1 and BRCA2 proteins and screening and therapeutic methods based on characterized BRCA1 and BRCA2 proteins
US6020137A (en) * 1996-08-14 2000-02-01 Exact Laboratories, Inc. Methods for the detection of loss of heterozygosity
US6146828A (en) * 1996-08-14 2000-11-14 Exact Laboratories, Inc. Methods for detecting differences in RNA expression levels and uses therefor
US6100029A (en) * 1996-08-14 2000-08-08 Exact Laboratories, Inc. Methods for the detection of chromosomal aberrations
US5928870A (en) * 1997-06-16 1999-07-27 Exact Laboratories, Inc. Methods for the detection of loss of heterozygosity
US5952178A (en) 1996-08-14 1999-09-14 Exact Laboratories Methods for disease diagnosis from stool samples
US6300077B1 (en) 1996-08-14 2001-10-09 Exact Sciences Corporation Methods for the detection of nucleic acids
US6203993B1 (en) 1996-08-14 2001-03-20 Exact Science Corp. Methods for the detection of nucleic acids
CN1181422A (zh) * 1996-10-31 1998-05-13 上海市肿瘤研究所 与生长因子受体结合的多肽所构建的基因转移载体
KR20010082501A (ko) 1997-10-27 2001-08-30 개리 이. 프라이드만 4-아미노티아졸 유도체, 그 제조방법 및 싸이클린-의존성키나아제의 억제제로서의 이용방법
US6177410B1 (en) 1997-12-05 2001-01-23 Vanderbilt University Therapeutic methods for prostate cancer
US6897018B1 (en) 1998-02-25 2005-05-24 The United States Of America As Represented By The Department Of Health And Human Services DLC-1 gene deleted in cancers
AU2892199A (en) * 1998-03-03 1999-09-20 Affymetrix, Inc. Cell cycle regulated genes
US6183958B1 (en) * 1998-05-06 2001-02-06 Variagenics, Inc. Probes for variance detection
US6225456B1 (en) 1998-05-07 2001-05-01 University Technololy Corporation Ras suppressor SUR-5
US6489305B1 (en) * 1998-05-08 2002-12-03 Canji, Inc. Methods and compositions for the treatment of ocular diseases
US6506889B1 (en) 1998-05-19 2003-01-14 University Technology Corporation Ras suppressor SUR-8 and related compositions and methods
US6576420B1 (en) * 1998-06-23 2003-06-10 Regents Of The University Of California Method for early diagnosis of, and determination of prognosis in, cancer
DE19829473C2 (de) * 1998-07-01 2000-08-10 Magnus Von Knebel Doeberitz Ch Verfahren zur frühen Diagnose von Carcinomen
US7306926B2 (en) * 1998-07-01 2007-12-11 Mtm Laboratories Ag Method for detecting carcinomas in a solubilized cervical body sample
KR20000038917A (ko) * 1998-12-10 2000-07-05 성재갑 곤충세포를 이용한 cdk6/p16 복합체의 제조방법
US6280947B1 (en) 1999-08-11 2001-08-28 Exact Sciences Corporation Methods for detecting nucleotide insertion or deletion using primer extension
US6174681B1 (en) * 1999-03-05 2001-01-16 Mayo Foundation For Medical Education And Research Method and probe set for detecting cancer
AU5446700A (en) * 1999-05-28 2000-12-18 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The A combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector
US6440706B1 (en) 1999-08-02 2002-08-27 Johns Hopkins University Digital amplification
WO2001090332A2 (en) 2000-05-23 2001-11-29 The University Of Texas System Dna repair polypeptides and methods of use
DE50113102D1 (de) * 2000-06-27 2007-11-22 Von Recklinghausen Ges E V Verfahren zur Ermittlung von Daten zur präsymptomatischen oder pränatalen Diagnose von Typ 1 Neurofibromatose
US7906492B2 (en) * 2001-01-16 2011-03-15 Sloan-Kettering Institute For Cancer Research Therapy-enhancing glucan
EP1499180A4 (en) * 2002-04-16 2006-09-13 Dana Farber Cancer Inst Inc CANCER MODELS
US6909444B2 (en) * 2002-09-09 2005-06-21 Dai Nippon Printing Co., Ltd. Transfer ribbon, image expressing medium and method for production of them
US20070270504A1 (en) * 2003-06-20 2007-11-22 Avalon Pharmaceuticals, Inc. Identification of Therapeutic Agents Using Genetic Fingerprinting
ATE289685T1 (de) * 2003-08-25 2005-03-15 Mtm Lab Ag Verfahren zum nachweis von karzinomen in solubilisierten zervikalen körperproben
US20050075543A1 (en) * 2003-10-03 2005-04-07 Calabrese Charles A. Method of anonymous medical testing and providing the patient with the test results
CN101507822B (zh) * 2003-11-24 2012-06-06 坎吉有限公司 皮肤瘢痕形成的减少
PL1799230T3 (pl) 2004-08-27 2013-05-31 Cyclacel Ltd Purynowe i pirymidynowe inhibitory CDK i ich zastosowanie do leczenia chorób autoimmunologicznych
WO2006047787A2 (en) 2004-10-27 2006-05-04 Exact Sciences Corporation Method for monitoring disease progression or recurrence
US9777314B2 (en) 2005-04-21 2017-10-03 Esoterix Genetic Laboratories, Llc Analysis of heterogeneous nucleic acid samples
US8323644B2 (en) * 2006-01-17 2012-12-04 Sloan-Kettering Institute For Cancer Research Therapy-enhancing glucan
US20090053221A1 (en) * 2006-01-17 2009-02-26 Cheung Nai-Kong V Immune response enhancing glucan
EP2193210B1 (en) * 2007-09-17 2014-11-12 Koninklijke Philips N.V. Method for the analysis of ovarian cancer disorders
WO2009077642A1 (en) * 2007-12-19 2009-06-25 University Of Helsinki Screening method
WO2010068850A1 (en) * 2008-12-12 2010-06-17 Georgetown University Methods of diagnosing and treating cancer
US8715937B2 (en) 2010-11-15 2014-05-06 Exact Sciences Corporation Mutation detection assay
WO2013058868A2 (en) 2011-10-18 2013-04-25 Exact Sciences Corporation Multiplexed kras mutation detection assay
RU2484096C1 (ru) * 2012-02-08 2013-06-10 Общество с ограниченной ответственностью "Технофарма" ОДНОДОМЕННОЕ АНТИТЕЛО, СПЕЦИФИЧЕСКИ СВЯЗЫВАЮЩЕЕ БЕЛОК S100A4/Mts1, ПРИМЕНЕНИЕ ПОЛУЧЕННОГО АНТИТЕЛА ДЛЯ ДЕТЕКЦИИ ЭТОГО БЕЛКА
CN103127528B (zh) * 2012-09-14 2016-04-20 苏州大学 人类dcx基因在制备胶质瘤放疗增敏剂中的应用
CN106701920A (zh) * 2016-11-25 2017-05-24 苏州首度基因科技有限责任公司 一种预测结直肠癌肝转移的试剂盒和使用方法
RU2694231C1 (ru) * 2018-01-09 2019-07-10 Федеральное Государственное Бюджетное Образовательное Учреждение Высшего Образования "Башкирский Государственный Педагогический Университет Им. М. Акмуллы" Способ определения предрасположенности к онкопатологии

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5763257A (en) * 1984-05-29 1998-06-09 Genencor International, Inc. Modified subtilisins having amino acid alterations
WO1992000757A1 (en) * 1990-07-09 1992-01-23 Research Corporation Technologies, Inc. Diagnosis of metastatic cancer by the mts-1 gene
US5889169A (en) * 1991-05-16 1999-03-30 Cold Spring Harbor Laboratory Cell cycle regulatory protein p16 gene
US6211334B1 (en) * 1992-10-16 2001-04-03 Cold Spring Harbor Cell-cycle regulatory proteins, and uses related thereto
US5962316A (en) * 1992-10-16 1999-10-05 Cold Spring Harbor Laboratory Cell-cycle regulatory proteins, and uses related thereto
CA2146965C (en) * 1992-10-16 2003-07-29 David H. Beach Cyclin complex rearrangement and uses related thereto
US6043030A (en) * 1992-12-17 2000-03-28 Cold Spring Harbor Laboratory Cell-cycle regulatory proteins, and uses related thereto
US5919997A (en) * 1993-11-18 1999-07-06 Cold Spring Habor Labortary Transgenic mice having modified cell-cycle regulation
RU2161309C2 (ru) * 1994-03-18 2000-12-27 Исследовательский Фонд Университета Юты, Мутации гена мтs в зародышевой линии и способ выявления предрасположенности к злокачественным опухолям в гене мтs
US6689561B1 (en) * 1994-04-14 2004-02-10 The Regents Of The University Of California Tumor suppressor gene and methods for detection of cancer, monitoring of tumor progression and cancer treatment
US6033847A (en) * 1995-02-06 2000-03-07 St. Jude Children's Research Hospital InK4c-p18 and InK4d-p19, inhibitors of cyclin-dependent kinases CDK4 and CDK6, and uses thereof

Also Published As

Publication number Publication date
NO954495L (no) 1996-01-17
US5801236A (en) 1998-09-01
US6218146B1 (en) 2001-04-17
AU2378995A (en) 1995-10-09
AU685627B2 (en) 1998-01-22
NO954495D0 (no) 1995-11-08
US6037462A (en) 2000-03-14
US6180776B1 (en) 2001-01-30
CA2162150C (en) 2010-03-30
EP0702730A4 (en) 1997-05-07
CA2162150A1 (en) 1995-09-28
JPH08510391A (ja) 1996-11-05
US6090578A (en) 2000-07-18
FI955416A (fi) 1996-01-09
US5624819A (en) 1997-04-29
WO1995025813A1 (en) 1995-09-28
EP0702730A1 (en) 1996-03-27
US5994095A (en) 1999-11-30
US5739027A (en) 1998-04-14
RU2161309C2 (ru) 2000-12-27
NZ284612A (en) 1997-09-22
US6140473A (en) 2000-10-31
CN1128049A (zh) 1996-07-31

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