FI953442A - Frystorkade kulor innehållande gonadotropin - Google Patents

Frystorkade kulor innehållande gonadotropin Download PDF

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Publication number
FI953442A
FI953442A FI953442A FI953442A FI953442A FI 953442 A FI953442 A FI 953442A FI 953442 A FI953442 A FI 953442A FI 953442 A FI953442 A FI 953442A FI 953442 A FI953442 A FI 953442A
Authority
FI
Finland
Prior art keywords
pct
freeze
spheres containing
gonadotropin
dried spheres
Prior art date
Application number
FI953442A
Other languages
English (en)
Finnish (fi)
Other versions
FI112324B (sv
FI953442A0 (sv
Inventor
Arnold Titus Philip Skrabanja
Herman Vromans
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of FI953442A publication Critical patent/FI953442A/sv
Publication of FI953442A0 publication Critical patent/FI953442A0/sv
Application granted granted Critical
Publication of FI112324B publication Critical patent/FI112324B/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI953442A 1993-04-28 1995-07-14 Förfarande för framställning av gonadotropin innehållande lyosfär FI112324B (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP93201215 1993-04-28
EP93201215 1993-04-28
EP9401303 1994-04-25
PCT/EP1994/001303 WO1994025005A1 (en) 1993-04-28 1994-04-25 Lyospheres comprising gonadotropin

Publications (3)

Publication Number Publication Date
FI953442A true FI953442A (sv) 1995-07-14
FI953442A0 FI953442A0 (sv) 1995-07-14
FI112324B FI112324B (sv) 2003-11-28

Family

ID=8213798

Family Applications (1)

Application Number Title Priority Date Filing Date
FI953442A FI112324B (sv) 1993-04-28 1995-07-14 Förfarande för framställning av gonadotropin innehållande lyosfär

Country Status (16)

Country Link
US (1) US5656597A (sv)
EP (1) EP0695171B1 (sv)
JP (1) JPH08509483A (sv)
KR (1) KR100334856B1 (sv)
AT (1) ATE146360T1 (sv)
AU (1) AU679986B2 (sv)
CA (1) CA2150251C (sv)
DE (1) DE69401204T2 (sv)
DK (1) DK0695171T3 (sv)
ES (1) ES2098140T3 (sv)
FI (1) FI112324B (sv)
GR (1) GR3022510T3 (sv)
HK (1) HK1002017A1 (sv)
NO (1) NO311168B1 (sv)
NZ (1) NZ265956A (sv)
WO (1) WO1994025005A1 (sv)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL120202A (en) 1996-03-07 2001-03-19 Akzo Nobel Nv Container with freeze-dried vaccine components
GB2329124B (en) * 1997-09-12 2002-05-08 Hiran Asoka Malinga Ratwatte Method of forming dose units of active agents
EP1658840A1 (en) * 1999-04-05 2006-05-24 Mannkind Corporation Methods for fine powder formation
CA2367131C (en) * 1999-04-05 2007-07-03 Solomon S. Steiner Methods for fine powder formation
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
DE60318938T2 (de) 2002-03-20 2009-01-22 Mannkind Corp., Valencia Inhalationsgerät
US20040248784A1 (en) * 2003-06-03 2004-12-09 Marco Filicori Unitary combinations of FSH and hCG
EP1643972A4 (en) * 2003-06-27 2010-01-20 Smithkline Beecham Corp STABILIZED LIPOSOMAL TOPOTECAN COMPOSITION AND METHOD
ES2385934T3 (es) 2004-08-20 2012-08-03 Mannkind Corporation Catálisis de la síntesis de dicetopiperazina.
EP2314298B1 (en) 2004-08-23 2015-05-27 MannKind Corporation Microparticles comprising diketopiperazine salts for drug delivery
KR20160022404A (ko) 2005-09-14 2016-02-29 맨카인드 코포레이션 활성제에 대한 결정질 미립자 표면의 친화력의 증가를 기반으로 하는 약물 제제화의 방법
MX2008010721A (es) 2006-02-22 2008-09-01 Mannkind Corp Un metodo para mejorar las propiedades farmaceuticas de microparticulas que contienen dicetopiperazina y un agente activo.
TWI436789B (zh) 2008-01-21 2014-05-11 Intervet Int Bv 含有藥學化合物的顆粒之冷凍乾燥方法及含有此顆粒的藥學包
CN101959527B (zh) 2008-03-05 2016-04-20 赛诺菲巴斯德有限公司 一种使含佐剂的疫苗组合物稳定的方法
CN101269215B (zh) * 2008-05-15 2011-03-23 上海天伟生物制药有限公司 一种糖蛋白激素组合物
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
EP3281663B8 (en) 2008-06-13 2022-09-21 MannKind Corporation Breath powered dry powder inhaler for drug delivery
MX2010014240A (es) 2008-06-20 2011-03-25 Mankind Corp Un metodo y aparato interactivo para perfilar en tiempo real esfuerzos de inhalacion.
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
CA2754595C (en) 2009-03-11 2017-06-27 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
US8551528B2 (en) 2009-06-12 2013-10-08 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
EP2496295A1 (en) 2009-11-03 2012-09-12 MannKind Corporation An apparatus and method for simulating inhalation efforts
BR112012033060A2 (pt) 2010-06-21 2018-02-27 Mannkind Corp métodos de sistema de liberação de fármaco em pó seco
KR101940832B1 (ko) 2011-04-01 2019-01-21 맨카인드 코포레이션 의약 카트리지용 블리스터 패키지
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
EP2776053A1 (en) 2011-10-24 2014-09-17 MannKind Corporation Methods and compositions for treating pain
SG11201500218VA (en) 2012-07-12 2015-03-30 Mannkind Corp Dry powder drug delivery systems and methods
EP2911690A1 (en) 2012-10-26 2015-09-02 MannKind Corporation Inhalable influenza vaccine compositions and methods
EP3587404B1 (en) 2013-03-15 2022-07-13 MannKind Corporation Microcrystalline diketopiperazine compositions, methods for preparation and use thereof
CA2920488C (en) 2013-08-05 2022-04-26 Mannkind Corporation Insufflation apparatus and methods
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
WO2017066134A1 (en) * 2015-10-16 2017-04-20 Merck Sharp & Dohme Corp. Processes for preparing formulations for gastrointestinal-targeted therapies

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932943A (en) * 1970-08-14 1976-01-20 E. I. Du Pont De Nemours And Company Method of preparation of lyophilized biological products
EP0081913B1 (en) * 1981-12-11 1985-06-26 JOHN WYETH & BROTHER LIMITED Process and apparatus for freezing a liquid medium
JPS60258125A (ja) * 1984-06-06 1985-12-20 Hayashibara Biochem Lab Inc 蛋白性生理活性物質を含有する水溶性乾燥物
CA2030551C (en) * 1989-05-01 1998-08-25 Wayne Gombotz Process for producing small particles of biologically active molecules
IE64738B1 (en) * 1990-03-20 1995-09-06 Akzo Nv Stabilized gonadotropin containing preparations

Also Published As

Publication number Publication date
FI112324B (sv) 2003-11-28
EP0695171A1 (en) 1996-02-07
CA2150251C (en) 2005-02-22
DK0695171T3 (da) 1997-06-02
NO954320D0 (no) 1995-10-27
DE69401204D1 (de) 1997-01-30
US5656597A (en) 1997-08-12
HK1002017A1 (en) 1998-07-24
FI953442A0 (sv) 1995-07-14
NO311168B1 (no) 2001-10-22
NZ265956A (en) 1996-09-25
AU679986B2 (en) 1997-07-17
DE69401204T2 (de) 1997-06-05
WO1994025005A1 (en) 1994-11-10
EP0695171B1 (en) 1996-12-18
CA2150251A1 (en) 1994-11-10
ES2098140T3 (es) 1997-04-16
NO954320L (no) 1995-10-27
AU6648894A (en) 1994-11-21
KR100334856B1 (ko) 2002-11-07
ATE146360T1 (de) 1997-01-15
JPH08509483A (ja) 1996-10-08
GR3022510T3 (en) 1997-05-31
KR950703934A (ko) 1995-11-17

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Owner name: N.V. ORGANON

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