FI952445A - Pneumokokiantigeenien annostelu limakalvojen kautta - Google Patents

Pneumokokiantigeenien annostelu limakalvojen kautta Download PDF

Info

Publication number
FI952445A
FI952445A FI952445A FI952445A FI952445A FI 952445 A FI952445 A FI 952445A FI 952445 A FI952445 A FI 952445A FI 952445 A FI952445 A FI 952445A FI 952445 A FI952445 A FI 952445A
Authority
FI
Finland
Prior art keywords
mucosal administration
pneumococci
pneumococcal antigens
against pneumococcal
whole
Prior art date
Application number
FI952445A
Other languages
English (en)
Swedish (sv)
Other versions
FI952445A0 (fi
Inventor
David E Briles
Hong-Yin Wu
Original Assignee
Uab Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/246,636 external-priority patent/US5965141A/en
Application filed by Uab Research Foundation filed Critical Uab Research Foundation
Publication of FI952445A0 publication Critical patent/FI952445A0/fi
Publication of FI952445A publication Critical patent/FI952445A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/28Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Vibrionaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/746Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
FI952445A 1994-05-20 1995-05-19 Pneumokokiantigeenien annostelu limakalvojen kautta FI952445A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/246,636 US5965141A (en) 1991-02-15 1994-05-20 Epitopic regions of pneumococcal surface protein a
US08/312,949 US6027734A (en) 1991-02-15 1994-09-30 Mucosal administration of pneumococcal antigens

Publications (2)

Publication Number Publication Date
FI952445A0 FI952445A0 (fi) 1995-05-19
FI952445A true FI952445A (fi) 1995-11-21

Family

ID=26938117

Family Applications (1)

Application Number Title Priority Date Filing Date
FI952445A FI952445A (fi) 1994-05-20 1995-05-19 Pneumokokiantigeenien annostelu limakalvojen kautta

Country Status (13)

Country Link
US (1) US6027734A (fi)
EP (1) EP0682950B1 (fi)
JP (1) JP2747435B2 (fi)
AT (1) ATE182270T1 (fi)
AU (1) AU698724B2 (fi)
CA (1) CA2149703A1 (fi)
DE (1) DE69510858T2 (fi)
DK (1) DK0682950T3 (fi)
ES (1) ES2135663T3 (fi)
FI (1) FI952445A (fi)
GR (1) GR3031491T3 (fi)
IL (1) IL113772A0 (fi)
NO (1) NO951982L (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2222965A1 (en) * 1995-06-02 1996-12-12 Uab Research Foundation Oral administration of pneumococcal antigens
ZA964896B (en) * 1995-06-07 1997-01-08 Connaught Lab Expression of lipoproteins
US7078042B2 (en) * 1995-09-15 2006-07-18 Uab Research Foundation Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor
WO1999051266A2 (en) * 1998-04-07 1999-10-14 Medimmune, Inc. Derivatives of pneumococcal choline binding proteins for vaccines
US20010016200A1 (en) * 1998-04-23 2001-08-23 Briles David E. Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor
WO2002029100A1 (en) * 2000-09-29 2002-04-11 Genomics Collaborative, Inc. Methods of diagnosing community acquired pneumonia (cap) and predisposition or susceptibility for cap and associated septic shock through detection of gene polymorphisms
JP4304077B2 (ja) 2002-02-13 2009-07-29 イミュノロジー ラボラトリーズ インコーポレイテッド 微生物感染の処置のための組成物および方法
WO2005021713A2 (en) 2003-06-20 2005-03-10 Protein Sciences Corporation Vectors expressing sars immunogens, compositions containing such vectors or expression products thereof, methods and assays for making and using
JP2007512006A (ja) * 2003-11-10 2007-05-17 ザ ユーエービー リサーチ ファウンデーション 細菌輸送およびcns侵襲を低減させるための組成物およびこの組成物を使用する方法
JP5081243B2 (ja) * 2006-08-17 2012-11-28 ザ ユーエービー リサーチ ファウンデーション 肺炎球菌抗原を被検体における肺炎球菌性肺炎の指標とする方法
MX2009012676A (es) * 2007-05-23 2010-02-12 Uab Research Foundation Neuraminidasa neumococica no toxica y sus usos.
ES2763415T3 (es) 2012-09-19 2020-05-28 Univ Osaka Vacuna neumocócica que contiene proteína A superficial neumocócica
US11053532B2 (en) 2017-04-19 2021-07-06 CAP Diagnostics, LLC Methods for treating polymicrobial infections

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6444889U (fi) * 1987-09-14 1989-03-17
JP2849632B2 (ja) * 1988-04-08 1999-01-20 社団法人北里研究所 ワクチン製剤
ZA921025B (en) * 1991-02-15 1992-11-25 Uab Research Foundation Structural gene of pneumococcal protein
AU5958594A (en) * 1992-12-24 1994-07-19 Med Immune, Inc. Method of protection against (streptococcus pneumoniae) with transformed mycobacteria
CA2116261A1 (en) * 1993-04-20 1994-10-21 David E. Briles Epitopic regions of pneumococcal surface protein a

Also Published As

Publication number Publication date
JPH0840927A (ja) 1996-02-13
NO951982L (no) 1995-11-21
FI952445A0 (fi) 1995-05-19
ES2135663T3 (es) 1999-11-01
EP0682950A1 (en) 1995-11-22
IL113772A0 (en) 1995-08-31
DE69510858T2 (de) 2000-04-13
EP0682950B1 (en) 1999-07-21
AU2015095A (en) 1995-11-30
CA2149703A1 (en) 1995-11-21
DK0682950T3 (da) 1999-11-29
GR3031491T3 (en) 2000-01-31
JP2747435B2 (ja) 1998-05-06
AU698724B2 (en) 1998-11-05
ATE182270T1 (de) 1999-08-15
DE69510858D1 (de) 1999-08-26
US6027734A (en) 2000-02-22
NO951982D0 (no) 1995-05-19

Similar Documents

Publication Publication Date Title
FI952445A (fi) Pneumokokiantigeenien annostelu limakalvojen kautta
NO20015073L (no) Vaksiner
IL115047A (en) Immunogenic conjugates comprising pneumococcal polysaccharide and recombinant pneumolysin, vaccines comprising such conjugates and use of such vaccines in the manufacture of medicaments for immunizing against pneumococcal infections
KR890701758A (ko) 재조합 dna에서 유도한 보르데텔라 외독소 소단위체의 유사체 및 그를 포함하는 백신
ATE270707T1 (de) Entepneumovirus und entsprechendes impfstoff
BRPI9700768B8 (pt) vacina viva para combater infecção por streptococcus em cavalos.
LU91595I2 (fr) Combinaison d'anatoxine diphtérique, d'anatoxine tétanique, d'anatoxine coquelucheuse, d'hémagglutinine filamenteuse, de pertactine et de polyoside capsulaire d'haemophilus influenzae type b (InfanrixHib)
NO964413D0 (no) Gruppe A streptokokkisk polysakkarid, immunogene blandinger derav samt anvendelse derav
CA2022420A1 (en) Escherichia coli vaccine
ATE274919T1 (de) Feste dispergierende impfstoffe-zusammensetzung zur oralen verabreichung
HUP9801266A2 (hu) Multimer, rekombináns ureázvakcina
WO2003000204A8 (en) Multivalent mycoplasma bacterin
WO2003059385A3 (en) Hiv vaccine and method of use
WO1996039113A3 (en) Oral administration of pneumococcal antigens
WO2001022994A3 (en) Vaccines against neisseria infection
WO2003032917A3 (en) Hookworm vaccine
DE69333402D1 (en) Impfstoff beinhaltend bacterin und toxoid aus pasteurella haemolytica typ a-1
DK0535740T3 (da) Vaccine mod luftvejsinfektioner hos katte
CA2388054A1 (en) Compositions and methods for stimulating an immune response against infectious agents