FI952328A0 - Ligander av eck-reseptorer - Google Patents
Ligander av eck-reseptorerInfo
- Publication number
- FI952328A0 FI952328A0 FI952328A FI952328A FI952328A0 FI 952328 A0 FI952328 A0 FI 952328A0 FI 952328 A FI952328 A FI 952328A FI 952328 A FI952328 A FI 952328A FI 952328 A0 FI952328 A0 FI 952328A0
- Authority
- FI
- Finland
- Prior art keywords
- ligands
- eck
- disclosed
- eck receptor
- receptor
- Prior art date
Links
- 239000003446 ligand Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 101710146873 Receptor-binding protein Proteins 0.000 abstract 1
- 230000027455 binding Effects 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 108010004188 erythropoietin receptor (1-225) Proteins 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US97770892A | 1992-11-13 | 1992-11-13 | |
US14561693A | 1993-11-09 | 1993-11-09 | |
PCT/US1993/010879 WO1994011020A1 (en) | 1992-11-13 | 1993-11-12 | Eck receptor ligands |
Publications (2)
Publication Number | Publication Date |
---|---|
FI952328A0 true FI952328A0 (sv) | 1995-05-12 |
FI952328A FI952328A (sv) | 1995-07-10 |
Family
ID=26843152
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI952328A FI952328A (sv) | 1992-11-13 | 1995-05-12 | Ligander av eck-reseptorer |
Country Status (14)
Country | Link |
---|---|
US (2) | US5650504A (sv) |
EP (1) | EP0597503B1 (sv) |
JP (1) | JPH08505765A (sv) |
CN (1) | CN1094446A (sv) |
AT (1) | ATE172246T1 (sv) |
AU (1) | AU685765B2 (sv) |
CA (1) | CA2149333C (sv) |
DE (1) | DE69321555T2 (sv) |
DK (1) | DK0597503T3 (sv) |
ES (1) | ES2121915T3 (sv) |
FI (1) | FI952328A (sv) |
IL (1) | IL107599A0 (sv) |
NO (1) | NO951861L (sv) |
WO (1) | WO1994011020A1 (sv) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992007094A1 (en) * | 1990-10-16 | 1992-04-30 | The Regents Of The University Of Michigan | Cytokine-induced marker for inflammatory response |
US5824303A (en) | 1992-11-13 | 1998-10-20 | Amgen Inc. | Eck receptor ligands |
AU669960B2 (en) * | 1992-11-13 | 1996-06-27 | Immunex Corporation | Novel cytokine designated elk ligand |
US5516658A (en) * | 1993-08-20 | 1996-05-14 | Immunex Corporation | DNA encoding cytokines that bind the cell surface receptor hek |
US5747033A (en) * | 1993-10-28 | 1998-05-05 | Regeneron Pharmaceuticals, Inc. | Method of enhancing the biological activity of Eph family ligands |
IL113252A0 (en) * | 1994-04-04 | 1995-07-31 | Regeneration Pharmaceuticals I | Eph receptors binding ligands |
US6303769B1 (en) | 1994-07-08 | 2001-10-16 | Immunex Corporation | Lerk-5 dna |
AU716924B2 (en) * | 1994-10-27 | 2000-03-09 | Genentech Inc. | AL-1 neurotrophic factor, a ligand for an EPH related tyrosine kinase receptor |
US5759775A (en) * | 1994-10-27 | 1998-06-02 | Genetech, Inc. | Methods for detecting nucleic acids encoding AL--1 neurotrophic factor |
US6057124A (en) * | 1995-01-27 | 2000-05-02 | Amgen Inc. | Nucleic acids encoding ligands for HEK4 receptors |
US6100346A (en) * | 1995-03-06 | 2000-08-08 | Ethicon, Inc. | Copolymers of polyoxaamides |
US6610296B2 (en) | 1995-10-26 | 2003-08-26 | Genentech, Inc. | Methods of enhancing cognitive function using an AL-1 neurotrophic factor immunoadhesin |
US6887674B1 (en) | 1998-04-13 | 2005-05-03 | California Institute Of Technology | Artery- and vein-specific proteins and uses therefor |
US6864227B1 (en) | 1998-04-13 | 2005-03-08 | California Institute Of Technology | Artery-and vein-specific proteins and uses therefor |
PL199645B1 (pl) | 1998-12-23 | 2008-10-31 | Regeneron Pharma | Kwas nukleinowy, polipeptyd fuzyjny, kompozycja, wektor, wektor ekspresyjny, układ gospodarz wektor, sposób wytwarzania polipeptydu fuzyjnego, kwas nukleinowy i sposób wytwarzania polipeptydu fuzyjnego |
US6248725B1 (en) | 1999-02-23 | 2001-06-19 | Amgen, Inc. | Combinations and methods for promoting in vivo liver cell proliferation and enhancing in vivo liver-directed gene transduction |
EP1820860A3 (en) * | 1999-06-02 | 2008-03-19 | Genentech, Inc. | Methods and compositions for inhibiting neoplastic cell growth |
US6927203B1 (en) | 1999-08-17 | 2005-08-09 | Purdue Research Foundation | Treatment of metastatic disease |
US7192698B1 (en) | 1999-08-17 | 2007-03-20 | Purdue Research Foundation | EphA2 as a diagnostic target for metastatic cancer |
US7101976B1 (en) | 2000-09-12 | 2006-09-05 | Purdue Research Foundation | EphA2 monoclonal antibodies and methods of making and using same |
US20020192711A1 (en) * | 2001-04-20 | 2002-12-19 | Nestor John J. | Methods for identifying ligands of G-Protein-Coupled receptors |
CA2485373A1 (en) * | 2002-05-10 | 2003-11-20 | Medimmune, Inc. | Epha2 monoclonal antibodies and methods of use thereof |
US20050152899A1 (en) * | 2002-05-10 | 2005-07-14 | Kinch Michael S. | EphA2 agonistic monoclonal antibodies and methods of use thereof |
US20040091486A1 (en) * | 2002-05-10 | 2004-05-13 | Kinch Michael S. | EphA2 agonistic monoclonal antibodies and methods of use thereof |
WO2004028551A1 (en) | 2002-09-24 | 2004-04-08 | The Burnham Institute | Novel agents that modulate eph receptor activity |
US7381410B2 (en) | 2003-03-12 | 2008-06-03 | Vasgene Therapeutics, Inc. | Polypeptide compounds for inhibiting angiogenesis and tumor growth |
AU2004220459B2 (en) | 2003-03-12 | 2010-08-05 | Vasgene Therapeutics, Inc. | Polypeptide compounds for inhibiting angiogenesis and tumor growth |
WO2004092343A2 (en) * | 2003-04-11 | 2004-10-28 | Medimmune, Inc. | Epha2, hypoproliferative cell disorders and epithelial and endothelial reconstitution |
WO2004091375A2 (en) * | 2003-04-11 | 2004-10-28 | Medimmune, Inc. | Epha2 and non-neoplastic hyperproliferative cell disorders |
EP1628992A4 (en) * | 2003-05-13 | 2008-04-16 | Novartis Vaccines & Diagnostic | METHODS FOR MODULATING METASTASIS AND SKELETAL RELATED EVENTS RESULTING FROM METASTASES |
EP1730196B1 (en) | 2004-03-12 | 2010-12-22 | Vasgene Therapeutics, Inc. | Antibodies binding to ephb4 for inhibiting angiogenesis and tumor growth |
KR20070034465A (ko) | 2004-03-12 | 2007-03-28 | 바스진 테라퓨틱스, 인크. | 혈관형성 및 종양 성장을 억제하기 위한 폴리펩티드 화합물 |
ES2529451T3 (es) | 2004-09-23 | 2015-02-20 | Vasgene Therapeutics, Inc. | Compuestos polipeptídicos para inhibir la angiogénesis y el crecimiento tumoral |
CA2595892A1 (en) | 2005-01-27 | 2006-08-03 | The Burnham Institute | Ephb receptor-binding peptides |
BRPI0815399A2 (pt) | 2007-08-13 | 2019-09-24 | Vasgene Therapeutics Inc | tratamento de câncer usando anticorpos humanizados que se ligam ephb4 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL9001052A (nl) * | 1990-05-02 | 1991-12-02 | Tno | Werkwijze voor het bepalen van een specifiek ligand in een vloeibaar monster met behulp van een evanescent veld, alsook een daarvoor geschikt onderdeel van de benodigde meetinrichting. |
WO1992007094A1 (en) * | 1990-10-16 | 1992-04-30 | The Regents Of The University Of Michigan | Cytokine-induced marker for inflammatory response |
-
1993
- 1993-11-12 AU AU55997/94A patent/AU685765B2/en not_active Ceased
- 1993-11-12 CA CA002149333A patent/CA2149333C/en not_active Expired - Fee Related
- 1993-11-12 JP JP6512336A patent/JPH08505765A/ja not_active Ceased
- 1993-11-12 WO PCT/US1993/010879 patent/WO1994011020A1/en active Application Filing
- 1993-11-12 IL IL10759993A patent/IL107599A0/xx unknown
- 1993-11-13 CN CN93121321A patent/CN1094446A/zh active Pending
- 1993-11-15 AT AT93118469T patent/ATE172246T1/de not_active IP Right Cessation
- 1993-11-15 EP EP93118469A patent/EP0597503B1/en not_active Expired - Lifetime
- 1993-11-15 ES ES93118469T patent/ES2121915T3/es not_active Expired - Lifetime
- 1993-11-15 DK DK93118469T patent/DK0597503T3/da active
- 1993-11-15 DE DE69321555T patent/DE69321555T2/de not_active Expired - Fee Related
-
1995
- 1995-05-11 NO NO951861A patent/NO951861L/no not_active Application Discontinuation
- 1995-05-12 FI FI952328A patent/FI952328A/sv not_active Application Discontinuation
- 1995-05-24 US US08/448,736 patent/US5650504A/en not_active Expired - Lifetime
- 1995-05-30 US US08/452,779 patent/US5716934A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU685765B2 (en) | 1998-01-29 |
CA2149333A1 (en) | 1994-05-26 |
DE69321555D1 (de) | 1998-11-19 |
FI952328A (sv) | 1995-07-10 |
EP0597503A3 (en) | 1995-05-24 |
ATE172246T1 (de) | 1998-10-15 |
US5716934A (en) | 1998-02-10 |
US5650504A (en) | 1997-07-22 |
NO951861D0 (no) | 1995-05-11 |
IL107599A0 (en) | 1994-02-27 |
WO1994011020A1 (en) | 1994-05-26 |
DE69321555T2 (de) | 1999-06-24 |
AU5599794A (en) | 1994-06-08 |
CN1094446A (zh) | 1994-11-02 |
DK0597503T3 (da) | 1999-06-23 |
EP0597503B1 (en) | 1998-10-14 |
CA2149333C (en) | 2002-01-22 |
NO951861L (no) | 1995-07-11 |
JPH08505765A (ja) | 1996-06-25 |
ES2121915T3 (es) | 1998-12-16 |
EP0597503A2 (en) | 1994-05-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application lapsed |