FI951128A0 - Substituoituja N-etyyliglysiinijohdannaisia PNA- ja PNA-/DNA-hybridien valmistamiseksi - Google Patents

Substituoituja N-etyyliglysiinijohdannaisia PNA- ja PNA-/DNA-hybridien valmistamiseksi

Info

Publication number
FI951128A0
FI951128A0 FI951128A FI951128A FI951128A0 FI 951128 A0 FI951128 A0 FI 951128A0 FI 951128 A FI951128 A FI 951128A FI 951128 A FI951128 A FI 951128A FI 951128 A0 FI951128 A0 FI 951128A0
Authority
FI
Finland
Prior art keywords
pna
substituted
preparation
dna hybrids
ethylglycine
Prior art date
Application number
FI951128A
Other languages
English (en)
Swedish (sv)
Other versions
FI120199B (fi
FI951128A (fi
Inventor
Gerhard Breipohl
Eugen Uhlmann
Jochen Knolle
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI951128A0 publication Critical patent/FI951128A0/fi
Publication of FI951128A publication Critical patent/FI951128A/fi
Application granted granted Critical
Publication of FI120199B publication Critical patent/FI120199B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91Nitro radicals
    • C07D233/92Nitro radicals attached in position 4 or 5
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/26Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32Nitrogen atom
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
FI951128A 1994-03-14 1995-03-10 Substituoituja N-etyyliglysiinijohdannaisia, menetelmä niiden valmistamiseksi ja niiden käyttö PNA- ja PNA-/DNA-hybridien valmistamiseksi FI120199B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4408534 1994-03-14
DE4408534A DE4408534A1 (de) 1994-03-14 1994-03-14 Substituierte N-Ethyl-Glycinderivate zur Herstellung von PNA und PNA-/DNA-Hybriden

Publications (3)

Publication Number Publication Date
FI951128A0 true FI951128A0 (fi) 1995-03-10
FI951128A FI951128A (fi) 1995-09-15
FI120199B FI120199B (fi) 2009-07-31

Family

ID=6512698

Family Applications (1)

Application Number Title Priority Date Filing Date
FI951128A FI120199B (fi) 1994-03-14 1995-03-10 Substituoituja N-etyyliglysiinijohdannaisia, menetelmä niiden valmistamiseksi ja niiden käyttö PNA- ja PNA-/DNA-hybridien valmistamiseksi

Country Status (8)

Country Link
US (1) US6075143A (fi)
EP (1) EP0672661A1 (fi)
JP (1) JPH07258222A (fi)
AU (1) AU686729B2 (fi)
CA (1) CA2144474C (fi)
DE (1) DE4408534A1 (fi)
FI (1) FI120199B (fi)
NO (1) NO307705B1 (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6133444A (en) 1993-12-22 2000-10-17 Perseptive Biosystems, Inc. Synthons for the synthesis and deprotection of peptide nucleic acids under mild conditions
US6919441B2 (en) * 1994-03-14 2005-07-19 Aventis Pharma Deutschland Gmbh Polyamide-oligonucleotide derivatives, their preparation and use
JP2001518054A (ja) * 1995-06-07 2001-10-09 パーセプティブ バイオシステムズ,インコーポレーテッド Pna−dnaキメラと、このキメラ合成用のpnaシントン
DE19532553A1 (de) * 1995-09-04 1997-03-06 Hoechst Ag Verfahren zur Herstellung substituierter N-Ethyl-Glycinderivate
US6191165B1 (en) 1996-05-31 2001-02-20 Allelix Neuroscience Inc. Pharmaceutical for treatment of neurological and neuropsychiatric disorders
DE19640974A1 (de) * 1996-10-04 1998-04-16 Bayer Ag Bausteine für DNA/PNA-Cooligomere
CA2290614C (en) * 1997-05-14 2010-09-21 Morphochem Ag Process for the preparation of polymers having nucleobases as side groups
US9879012B2 (en) 2012-03-29 2018-01-30 Regents Of The University Of Colorado, A Body Corporate Click nucleic acids
US10017510B2 (en) 2014-02-06 2018-07-10 The Regents Of The University Of Colorado, A Body Corporate Thiol-X click foldamers for polymer affinity and catalysis libraries
CN105541728B (zh) * 2015-07-27 2018-07-24 宁夏联森生物科技有限公司 一种n-4苯甲酰基胞嘧啶的制备方法
US10508116B2 (en) 2016-10-07 2019-12-17 The Regents Of The University Of Colorado, A Body Click nucleic acid polymers and methods of use

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2627988A1 (de) * 1976-06-23 1978-01-05 Max Planck Gesellschaft Sekretinbestimmung
US4213968A (en) * 1978-06-05 1980-07-22 Coy David Howard Enkephalin derivatives
US4213893A (en) * 1978-10-12 1980-07-22 Miles Laboratories, Inc. Flavin adenine dinucleotide-labeled conjugates for use in specific binding assays
JPS55135595A (en) * 1979-04-03 1980-10-22 Toyo Soda Mfg Co Ltd Preparation of dipeptide
US5470974A (en) * 1985-03-15 1995-11-28 Neu-Gene Development Group Uncharged polynucleotide-binding polymers
CS263951B1 (en) * 1985-04-25 1989-05-12 Antonin Holy 9-(phosponylmethoxyalkyl)adenines and method of their preparation
US5227497A (en) * 1988-04-04 1993-07-13 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Process for preparing N2 -(1-carboxy-3-phenylpropyl)-L-lysine derivative
EP0350145A3 (en) * 1988-04-28 1990-07-04 Yamanouchi Pharmaceutical Co. Ltd. Pyridylthiazolidine carboxamide derivatives and their intermediates and production of both
DE4016596A1 (de) * 1990-05-23 1991-11-28 Hoechst Ag Ein neues kupplungsreagenz fuer die peptidsynthese
US5614498A (en) * 1990-06-07 1997-03-25 Banyu Pharmaceutical Co., Ltd. Endothelin antagonistic substance
DK51092D0 (da) * 1991-05-24 1992-04-15 Ole Buchardt Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf
US5539082A (en) * 1993-04-26 1996-07-23 Nielsen; Peter E. Peptide nucleic acids
MX9207334A (es) * 1991-12-18 1993-08-01 Glaxo Inc Acidos nucleicos peptidicos y formulacion farma- ceutica que los contiene
US5480899A (en) * 1992-04-30 1996-01-02 Taiho Pharmaceutical Co., Ltd. Oxazolidine derivatives and pharmaceutically acceptable salts thereof
DE4331012A1 (de) * 1993-09-13 1995-03-16 Bayer Ag Nukleinsäuren-bindende Oligomere mit N-Verzweigung für Therapie und Diagnostik
JPH11503713A (ja) * 1993-12-22 1999-03-30 パーセプティブ・バイオシステムズ・インコーポレーテッド ペプチド核酸合成用のグアニンシントンと、その調製方法
MY119161A (en) * 1994-04-18 2005-04-30 Novartis Ag Delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides with enzyme especially renin inhibiting activities

Also Published As

Publication number Publication date
AU1479995A (en) 1995-09-21
DE4408534A1 (de) 1995-09-28
NO950959L (no) 1995-09-15
FI120199B (fi) 2009-07-31
FI951128A (fi) 1995-09-15
JPH07258222A (ja) 1995-10-09
CA2144474C (en) 2010-11-30
NO950959D0 (no) 1995-03-13
US6075143A (en) 2000-06-13
AU686729B2 (en) 1998-02-12
NO307705B1 (no) 2000-05-15
EP0672661A1 (de) 1995-09-20
CA2144474A1 (en) 1995-09-15

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