FI94314B - Förfarande för framställning av salicylsyraderivathaltigt ämne mot mjällbildande hudsjukdomar - Google Patents
Förfarande för framställning av salicylsyraderivathaltigt ämne mot mjällbildande hudsjukdomar Download PDFInfo
- Publication number
- FI94314B FI94314B FI891357A FI891357A FI94314B FI 94314 B FI94314 B FI 94314B FI 891357 A FI891357 A FI 891357A FI 891357 A FI891357 A FI 891357A FI 94314 B FI94314 B FI 94314B
- Authority
- FI
- Finland
- Prior art keywords
- salicylic acid
- weight
- process according
- acid
- aliphatic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
- Saccharide Compounds (AREA)
Claims (9)
1. Förfarande för framställning av salicylsyraderivathaltigt ämne för lokal behandling av lepidosa hudsjukdomar i human- 5 och animalmedicin, kännetecknat därav, att 4-10 vikt-% salicylsyra finfördelas med 1-7 vikt-% alifa-tisk 1,2-diol, tili vilken slutligen blandas 83 - 95 vikt-% fettolja tili en klar, oljeaktig lösning, varvid summan av produktens ämneskomponenters vikt-delar är 100. 10
2. Förfarande enligt patentkrav 1, kännetecknat därav, att den alifatiska 1,2-diolen är 1,2-propandiol eller butylenglykol, med intilliggande hydroxylgrupper. 15
3. Förfarande enligt patentkrav 2, kännetecknat därav, att fettoljan är en vegetabilisk triglycerid.
4. Förfarandet enligt nägot av patentkraven 1-3, kännetecknat därav, att tili den finfördelade salicyl- 20 syran ja den alifatiska 1,2-diolen sätts under blandning ätminstone en medelläng fettsyraester av en alkohol, vilken alkohol är en 1- eller 2-värd alkohol eller glycerin.
5. Förfarande enligt patentkrav 4, kännetecknat 25 därav, att som fettolja används en medelläng fettsyras trig- • lycerid.
6. Förfarande enligt patentkrav 5, kännetecknat därav, att den medellänga fettsyran är kaprylsyra, kaprinsyra 20 eller deras blandning.
7. Förfarande enligt patentkrav 6, kännetecknat därav, att 4-7,5 vikt-% salicylsyra finfördelas tillsammans med 1 - 4,5 vikt-% 1,2-propandiol och slutligen tillsätts 35 88 - 95 vikt-% triglycerid av kaprylsyra, kaprinsyra eller deras blandning under blandning för bildning av en klar, oljeaktig lösning. 9431 4
8. Förfarande enligt nägot av patentkraven 1-7, k ä n -netecknat därav, att andelen alifatisk 1,2-diol väljes Sei, att en nästan mättad salicylsyralösning erhälles. 5
9. Förfarande enligt nägot av föregäende patentkrav, k ä n - netecknat därav, att mängden alifatisk 1,2-diol tilltar frän värdet 1 tili 2 och 4,5 tili värdet 7 vikt-% och salicylsyrans mängd frän värdet 4 tili 5 och 10 vikt-%, räknad pä ämnets totalvikt. li
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3724691 | 1987-07-25 | ||
| DE3724691A DE3724691C2 (de) | 1987-07-25 | 1987-07-25 | Pharmazeutisches Mittel zur lokalen Therapie von schuppenden Hautkrankheiten |
| PCT/EP1988/000649 WO1989000853A1 (en) | 1987-07-25 | 1988-07-19 | Agent containing salicylic acid for treating lepidosis |
| EP8800649 | 1988-07-19 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI891357A FI891357A (sv) | 1989-03-22 |
| FI891357A0 FI891357A0 (sv) | 1989-03-22 |
| FI94314B true FI94314B (sv) | 1995-05-15 |
| FI94314C FI94314C (sv) | 1995-08-25 |
Family
ID=6332361
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI891357A FI94314C (sv) | 1987-07-25 | 1989-03-22 | Förfarande för framställning av salicylsyraderivathaltigt ämne mot mjällbildande hudsjukdomar |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0325628B1 (sv) |
| JP (1) | JPH02500106A (sv) |
| AT (1) | ATE69550T1 (sv) |
| AU (1) | AU2072088A (sv) |
| DE (2) | DE3724691C2 (sv) |
| DK (1) | DK173547B1 (sv) |
| FI (1) | FI94314C (sv) |
| NO (1) | NO175885C (sv) |
| WO (1) | WO1989000853A1 (sv) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR1001303B (el) * | 1989-01-23 | 1993-07-30 | Wolff Chem Pharm Gmbh | Μεθοδος παρασκευης μεσου που περιεχει σαλικυλικο οξυ εναντιον απολεπιστικων νοσων της επιδερμιδας. |
| ATE91079T1 (de) * | 1989-01-25 | 1993-07-15 | Wolff Chem Pharm Gmbh | Salicylsaeurehaltiges mittel gegen schuppende hauterkrankungen. |
| GB9223034D0 (en) * | 1992-11-03 | 1992-12-16 | Surtech Int Ltd | Method and composition for prevention and/or treatment of dandruff and seborrhoeic dermatitis |
| SE9403541L (sv) * | 1994-10-14 | 1996-04-15 | Sven Moberg | Antimikrobiell komposition |
| US5736580A (en) * | 1994-11-14 | 1998-04-07 | Alza Croporation | Composition, device, and method for electrotransport agent delivery |
| US5990179A (en) * | 1995-04-28 | 1999-11-23 | Alza Corporation | Composition and method of enhancing electrotransport agent delivery |
| US5985316A (en) * | 1995-04-28 | 1999-11-16 | Alza Corporation | Composition and method of enhancing electrotransport agent delivery |
| ES2245465T3 (es) * | 1996-09-18 | 2006-01-01 | Applied Genetics Incorporated Dermatics | Dioles de compuestos de norborneno y norbornano para el tratamiento de trastornos de la pigmentacion, enfermedades neurodegenerativas o enfermedades proliferativas de la piel. |
| US6623724B2 (en) | 1996-09-18 | 2003-09-23 | Applied Genetics Incorporated Dermatics | Dermatological compositions and methods |
| DE10205193A1 (de) * | 2002-02-08 | 2003-08-21 | Beiersdorf Ag | Diolhaltige Reinigungszubereitungen |
| DE10341179A1 (de) † | 2003-09-06 | 2005-03-31 | Beiersdorf Ag | Wirkstoffkombination gegen Akne |
| WO2013093823A2 (en) | 2011-12-20 | 2013-06-27 | Vyome Biosciences Pvt Ltd | Topical oil composition for the treatment of fungal infections |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE762726C (de) * | 1942-05-02 | 1952-09-15 | Hydrierwerke A G Deutsche | Loesungsmittel bzw. Loesungsvermittler fuer Salicylsaeure |
| JPS57171912A (en) * | 1981-04-14 | 1982-10-22 | Sumitomo Chem Co Ltd | Cream |
| FR2585575B1 (fr) * | 1985-08-01 | 1989-03-03 | Pf Medicament | Compositions pharmaceutiques a activite keratolytique sous forme de gel comportant de l'acide salicylique hydro-alcoolique |
-
1987
- 1987-07-25 DE DE3724691A patent/DE3724691C2/de not_active Expired - Fee Related
-
1988
- 1988-07-19 AU AU20720/88A patent/AU2072088A/en not_active Abandoned
- 1988-07-19 AT AT88905833T patent/ATE69550T1/de not_active IP Right Cessation
- 1988-07-19 EP EP88905833A patent/EP0325628B1/de not_active Expired - Lifetime
- 1988-07-19 WO PCT/EP1988/000649 patent/WO1989000853A1/de active IP Right Grant
- 1988-07-19 DE DE8888905833T patent/DE3866344D1/de not_active Expired - Lifetime
- 1988-07-19 JP JP63505873A patent/JPH02500106A/ja active Pending
-
1989
- 1989-03-20 NO NO891220A patent/NO175885C/no not_active IP Right Cessation
- 1989-03-21 DK DK198901375A patent/DK173547B1/da not_active IP Right Cessation
- 1989-03-22 FI FI891357A patent/FI94314C/sv not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK137589D0 (da) | 1989-03-21 |
| WO1989000853A1 (en) | 1989-02-09 |
| DE3724691A1 (de) | 1989-02-02 |
| FI891357A (sv) | 1989-03-22 |
| NO891220D0 (no) | 1989-03-20 |
| ATE69550T1 (de) | 1991-12-15 |
| AU2072088A (en) | 1989-03-01 |
| JPH02500106A (ja) | 1990-01-18 |
| NO175885C (no) | 1994-12-28 |
| DE3866344D1 (de) | 1992-01-02 |
| EP0325628B1 (de) | 1991-11-21 |
| FI94314C (sv) | 1995-08-25 |
| EP0325628A1 (de) | 1989-08-02 |
| DK173547B1 (da) | 2001-02-19 |
| FI891357A0 (sv) | 1989-03-22 |
| NO891220L (no) | 1989-03-20 |
| DK137589A (da) | 1989-05-19 |
| DE3724691C2 (de) | 1999-03-18 |
| NO175885B (no) | 1994-09-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB | Publication of examined application | ||
| FG | Patent granted |
Owner name: MINNINGER, KONRAD |
|
| MA | Patent expired |