FI941377L - Neuroleptisiä 2-substituoituja perhydro-1-H-pyrido/1,2-a/-pyratsiineja - Google Patents

Neuroleptisiä 2-substituoituja perhydro-1-H-pyrido/1,2-a/-pyratsiineja Download PDF

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Publication number
FI941377L
FI941377L FI941377A FI941377A FI941377L FI 941377 L FI941377 L FI 941377L FI 941377 A FI941377 A FI 941377A FI 941377 A FI941377 A FI 941377A FI 941377 L FI941377 L FI 941377L
Authority
FI
Finland
Prior art keywords
pyrazines
neuroleptic
pyrido
substituted perhydro
perhydro
Prior art date
Application number
FI941377A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI941377A0 (fi
FI941377A7 (fi
Inventor
Gene Michael Bright
Kishor Amratlal Desai
Thomas Francis Seeger
Teresa Annette Smolarek
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI941377A0 publication Critical patent/FI941377A0/fi
Publication of FI941377A7 publication Critical patent/FI941377A7/fi
Publication of FI941377L publication Critical patent/FI941377L/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/582Recycling of unreacted starting or intermediate materials

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI941377A 1991-09-25 1992-08-14 Neuroleptisiä 2-substituoituja perhydro-1-H-pyrido/1,2-a/-pyratsiineja FI941377L (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76533291A 1991-09-25 1991-09-25
PCT/US1992/006625 WO1993006101A1 (en) 1991-09-25 1992-08-14 NEUROLEPTIC 2-SUBSTITUTED PERHYDRO-1-H-PYRIDO[1,2a]PYRAZINES

Publications (3)

Publication Number Publication Date
FI941377A0 FI941377A0 (fi) 1994-03-24
FI941377A7 FI941377A7 (fi) 1994-03-24
FI941377L true FI941377L (fi) 1994-03-24

Family

ID=25073279

Family Applications (1)

Application Number Title Priority Date Filing Date
FI941377A FI941377L (fi) 1991-09-25 1992-08-14 Neuroleptisiä 2-substituoituja perhydro-1-H-pyrido/1,2-a/-pyratsiineja

Country Status (25)

Country Link
US (1) US5565453A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0607163B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH08827B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1071167A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE146178T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU655071B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BR9206541A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2118936A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CZ (1) CZ281775B6 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE69215886T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK0607163T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2096099T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI941377L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR3022483T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HUT71488A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL103204A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MX (1) MX9205385A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MY (1) MY108303A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO941084D0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ244473A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL170889B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT100891A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TW215090B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO1993006101A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA927306B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5731307A (en) * 1994-09-30 1998-03-24 Pfizer, Inc. Neuroleptic 2,7-disubtituted perhydro-1h-pyrido 1, 2-A!pyrazines
EP0783503B1 (en) * 1994-09-30 2001-11-28 Pfizer Inc. 2,7-substituted octahydro-1h-pyrido[ 1,2-a]pyrazine derivatives
PA8469101A1 (es) * 1998-04-09 2000-09-29 Pfizer Prod Inc Ligandos azabiciclicos de receptores 5ht1
AP2005003390A0 (en) * 2003-03-12 2005-09-30 Pfizer Prod Inc Pyridyloxymethyl and benzisoxazole azabicyclic derivatives.
CA2891122C (en) 2012-11-14 2021-07-20 The Johns Hopkins University Methods and compositions for treating schizophrenia
KR102209418B1 (ko) * 2012-12-20 2021-01-29 얀센 파마슈티카 엔.브이. 감마 세크레타제 조절 인자로서의 신규 삼환 3,4-디하이드로-2H-피리도[1,2-α]피라진-1,6-디온 유도체
WO2014111457A1 (en) 2013-01-17 2014-07-24 Janssen Pharmaceutica Nv Novel substituted pyrido-piperazinone derivatives as gamma secretase modulators
US10562897B2 (en) 2014-01-16 2020-02-18 Janssen Pharmaceutica Nv Substituted 3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-diones as gamma secretase modulators

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4804663A (en) * 1985-03-27 1989-02-14 Janssen Pharmaceutica N.V. 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles
US4831031A (en) * 1988-01-22 1989-05-16 Pfizer Inc. Aryl piperazinyl-(C2 or C4) alkylene heterocyclic compounds having neuroleptic activity
US4957916A (en) * 1988-08-05 1990-09-18 Janssen Pharmaceutica N.V. Antipsychotic 3-piperazinylbenzazole derivatives
NZ230045A (en) * 1988-08-05 1990-11-27 Janssen Pharmaceutica Nv 3-piperazinylbenzazole derivatives and pharmaceutical compositions
MX19222A (es) * 1989-01-23 1993-12-01 Pfizer Agentes ansioliticos bis-aza-biciclicos
US4956368A (en) * 1989-07-24 1990-09-11 Bristol-Myers Company Metabolites and prodrug formulations of 8-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione

Also Published As

Publication number Publication date
MY108303A (en) 1996-09-30
TW215090B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-10-21
FI941377A0 (fi) 1994-03-24
NZ244473A (en) 1995-04-27
ZA927306B (en) 1994-03-24
MX9205385A (es) 1993-03-01
CZ395792A3 (en) 1994-05-18
PL170889B1 (pl) 1997-02-28
EP0607163A1 (en) 1994-07-27
AU655071B2 (en) 1994-12-01
US5565453A (en) 1996-10-15
DE69215886T2 (de) 1997-04-03
CZ281775B6 (cs) 1997-01-15
JPH08827B2 (ja) 1996-01-10
AU2460992A (en) 1993-04-27
EP0607163B1 (en) 1996-12-11
NO941084L (no) 1994-03-24
FI941377A7 (fi) 1994-03-24
IL103204A0 (en) 1993-02-21
GR3022483T3 (en) 1997-05-31
DK0607163T3 (da) 1997-03-17
IL103204A (en) 1996-05-14
WO1993006101A1 (en) 1993-04-01
NO941084D0 (no) 1994-03-24
ATE146178T1 (de) 1996-12-15
CA2118936A1 (en) 1993-04-01
PT100891A (pt) 1993-10-29
JPH06506701A (ja) 1994-07-28
BR9206541A (pt) 1995-04-25
DE69215886D1 (de) 1997-01-23
ES2096099T3 (es) 1997-03-01
CN1071167A (zh) 1993-04-21
HU9400851D0 (en) 1994-06-28
HUT71488A (en) 1995-11-28

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