FI940696A0 - Uudet pyratsiinijohdannaiset, niiden valmistus ja käyttö - Google Patents
Uudet pyratsiinijohdannaiset, niiden valmistus ja käyttöInfo
- Publication number
- FI940696A0 FI940696A0 FI940696A FI940696A FI940696A0 FI 940696 A0 FI940696 A0 FI 940696A0 FI 940696 A FI940696 A FI 940696A FI 940696 A FI940696 A FI 940696A FI 940696 A0 FI940696 A0 FI 940696A0
- Authority
- FI
- Finland
- Prior art keywords
- preparation
- pyrazine derivatives
- new pyrazine
- new
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Liquid Crystal Substances (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4127026A DE4127026A1 (de) | 1991-08-16 | 1991-08-16 | Neue pyrazinderivate, ihre herstellung und verwendung |
| DE19914130461 DE4130461A1 (de) | 1991-09-13 | 1991-09-13 | Neue pyrazinderivate, ihre herstellung und verwendung |
| PCT/EP1992/001738 WO1993004048A1 (de) | 1991-08-16 | 1992-07-31 | Neue pyrazinderivative, ihre herstellung und verwendung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI940696A0 true FI940696A0 (fi) | 1994-02-15 |
| FI940696A FI940696A (fi) | 1994-02-15 |
Family
ID=25906394
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI940696A FI940696A (fi) | 1991-08-16 | 1994-02-15 | Uudet pyratsiinijohdannaiset, niiden valmistus ja käyttö |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP0598770B1 (hu) |
| JP (1) | JPH06509798A (hu) |
| AT (1) | ATE159250T1 (hu) |
| AU (1) | AU669122B2 (hu) |
| CA (1) | CA2115755A1 (hu) |
| CZ (1) | CZ280760B6 (hu) |
| DE (1) | DE59208974D1 (hu) |
| DK (1) | DK0598770T3 (hu) |
| ES (1) | ES2108129T3 (hu) |
| FI (1) | FI940696A (hu) |
| GR (1) | GR3025742T3 (hu) |
| HK (1) | HK1003137A1 (hu) |
| HU (1) | HUT67661A (hu) |
| IE (1) | IE922592A1 (hu) |
| IL (1) | IL102814A0 (hu) |
| MX (1) | MX9204637A (hu) |
| NO (1) | NO301542B1 (hu) |
| NZ (1) | NZ243959A (hu) |
| RU (1) | RU2124008C1 (hu) |
| SG (1) | SG46307A1 (hu) |
| SK (1) | SK17594A3 (hu) |
| TW (1) | TW213903B (hu) |
| WO (1) | WO1993004048A1 (hu) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6645969B1 (en) | 1991-05-10 | 2003-11-11 | Aventis Pharmaceuticals Inc. | Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase |
| IL109570A0 (en) * | 1993-05-17 | 1994-08-26 | Fujisawa Pharmaceutical Co | Guanidine derivatives, pharmaceutical compositions containing the same and processes for the preparation thereof |
| DE4325822A1 (de) * | 1993-07-31 | 1995-02-02 | Hoechst Ag | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| US5852046A (en) * | 1993-08-03 | 1998-12-22 | Hoechst Aktiengesellschaft | Benzo-fused heterocyclic compounds having a 5-membered ring processes for their preparation their use as medicaments their use as diagnostic agents and medicaments containing them |
| DE4337609A1 (de) * | 1993-11-04 | 1995-05-11 | Boehringer Ingelheim Kg | Neue Pyrazincarboxamidderivate, ihre Herstellung und ihre Verwendung in Arzneimitteln |
| DE4412334A1 (de) * | 1994-04-11 | 1995-10-19 | Hoechst Ag | Substituierte N-Heteroaroylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| US5760230A (en) * | 1996-10-11 | 1998-06-02 | Bayer Aktiengesellschaft | 4, 4'-bridged bis-2, 4-diaminoquinazolines |
| US6420354B1 (en) * | 1998-06-08 | 2002-07-16 | Advanced Medicine, Inc. | Sodium channel drugs and uses |
| EP1182194A4 (en) | 1999-06-03 | 2004-02-11 | Takeda Chemical Industries Ltd | PERNASAL COMPOSITIONS |
| US6479498B1 (en) | 1999-06-04 | 2002-11-12 | Theravance, Inc. | Sodium channel drugs and uses |
| US6156758A (en) * | 1999-09-08 | 2000-12-05 | Isis Pharmaceuticals, Inc. | Antibacterial quinazoline compounds |
| PL212089B1 (pl) * | 2002-03-13 | 2012-08-31 | Janssen Pharmaceutica Nv | Związki heterocykliczne jako inhibitory deacetylazy histonowej, kompozycja farmaceutyczna je zawierająca, ich zastosowanie, sposób wytwarzania, sposób wykrywania lub identyfikacji HDAC oraz kompozycja |
| US8309562B2 (en) | 2003-07-03 | 2012-11-13 | Myrexis, Inc. | Compounds and therapeutical use thereof |
| WO2005023183A2 (en) | 2003-08-28 | 2005-03-17 | Nitromed, Inc. | Nitrosated ad nitrosylated diuretic compouds, compositions and methods of use |
| US8258145B2 (en) | 2005-01-03 | 2012-09-04 | Myrexis, Inc. | Method of treating brain cancer |
| CA2592900A1 (en) | 2005-01-03 | 2006-07-13 | Myriad Genetics Inc. | Nitrogen containing bicyclic compounds and therapeutical use thereof |
| JP2008531579A (ja) | 2005-02-24 | 2008-08-14 | ニトロメッド インコーポレーティッド | 酸化窒素増強利尿化合物、組成物および使用方法 |
| DE102008061247A1 (de) * | 2008-12-10 | 2010-06-24 | Christian-Albrechts-Universität Zu Kiel | Inhibitoren der Dimethylarginin Dimethylaminohydrolase |
| WO2012031563A1 (zh) * | 2010-09-10 | 2012-03-15 | 杭州本生药业有限公司 | 杂环氨基小檗胺衍生物、其制备方法和应用 |
| CN110041291B (zh) * | 2018-01-15 | 2021-02-26 | 北京采瑞医药科技研究院有限公司 | 一种玛咖酰胺衍生物及其制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL299931A (hu) * | 1962-10-30 | |||
| US3527758A (en) * | 1967-04-13 | 1970-09-08 | Merck & Co Inc | Process for the preparation of pyrazinoylguanidines from a pyrazinoic azide and a guanidine |
| US3539569A (en) * | 1968-08-21 | 1970-11-10 | Merck & Co Inc | Preparation of pyrazinoylguanidines from pyrazinoylureas |
| NL7803906A (nl) * | 1978-04-12 | 1979-10-16 | Noordvos Schroeven Bv | Werkwijze, inrichting en propeller voor het verdelen van een gasvormig, poedervormig of vloeibaar materiaal in een vloeistof. |
-
1992
- 1992-07-28 TW TW081105973A patent/TW213903B/zh active
- 1992-07-31 CZ CZ94337A patent/CZ280760B6/cs unknown
- 1992-07-31 RU RU94015265A patent/RU2124008C1/ru active
- 1992-07-31 JP JP5504057A patent/JPH06509798A/ja active Pending
- 1992-07-31 SK SK175-94A patent/SK17594A3/sk unknown
- 1992-07-31 DK DK92916697.3T patent/DK0598770T3/da active
- 1992-07-31 AU AU23870/92A patent/AU669122B2/en not_active Ceased
- 1992-07-31 ES ES92916697T patent/ES2108129T3/es not_active Expired - Lifetime
- 1992-07-31 DE DE59208974T patent/DE59208974D1/de not_active Expired - Fee Related
- 1992-07-31 AT AT92916697T patent/ATE159250T1/de not_active IP Right Cessation
- 1992-07-31 SG SG1996002613A patent/SG46307A1/en unknown
- 1992-07-31 EP EP92916697A patent/EP0598770B1/de not_active Expired - Lifetime
- 1992-07-31 HU HU9400430A patent/HUT67661A/hu unknown
- 1992-07-31 CA CA002115755A patent/CA2115755A1/en not_active Abandoned
- 1992-07-31 WO PCT/EP1992/001738 patent/WO1993004048A1/de active IP Right Grant
- 1992-08-11 MX MX9204637A patent/MX9204637A/es not_active IP Right Cessation
- 1992-08-14 IL IL102814A patent/IL102814A0/xx unknown
- 1992-08-14 NZ NZ243959A patent/NZ243959A/en unknown
- 1992-08-17 IE IE259292A patent/IE922592A1/en not_active IP Right Cessation
-
1994
- 1994-02-15 FI FI940696A patent/FI940696A/fi unknown
- 1994-02-15 NO NO940523A patent/NO301542B1/no unknown
-
1997
- 1997-12-23 GR GR970403392T patent/GR3025742T3/el unknown
-
1998
- 1998-03-17 HK HK98102228A patent/HK1003137A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CZ280760B6 (cs) | 1996-04-17 |
| CZ33794A3 (en) | 1994-07-13 |
| IL102814A0 (en) | 1993-01-31 |
| NO940523L (no) | 1994-02-15 |
| JPH06509798A (ja) | 1994-11-02 |
| NO940523D0 (no) | 1994-02-15 |
| SG46307A1 (en) | 1998-02-20 |
| TW213903B (hu) | 1993-10-01 |
| AU669122B2 (en) | 1996-05-30 |
| NZ243959A (en) | 1995-07-26 |
| HK1003137A1 (en) | 1998-10-09 |
| DK0598770T3 (da) | 1997-12-15 |
| MX9204637A (es) | 1993-02-01 |
| NO301542B1 (no) | 1997-11-10 |
| SK17594A3 (en) | 1994-12-07 |
| ES2108129T3 (es) | 1997-12-16 |
| EP0598770A1 (de) | 1994-06-01 |
| IE922592A1 (en) | 1993-02-24 |
| AU2387092A (en) | 1993-03-16 |
| WO1993004048A1 (de) | 1993-03-04 |
| RU94015265A (ru) | 1997-02-20 |
| HUT67661A (en) | 1995-04-28 |
| RU2124008C1 (ru) | 1998-12-27 |
| DE59208974D1 (de) | 1997-11-20 |
| HU9400430D0 (en) | 1994-05-30 |
| ATE159250T1 (de) | 1997-11-15 |
| EP0598770B1 (de) | 1997-10-15 |
| FI940696A (fi) | 1994-02-15 |
| CA2115755A1 (en) | 1993-03-04 |
| GR3025742T3 (en) | 1998-03-31 |
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