FI935452A7 - Hydroksiamidiinijohdannaiset - Google Patents

Hydroksiamidiinijohdannaiset Download PDF

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Publication number
FI935452A7
FI935452A7 FI935452A FI935452A FI935452A7 FI 935452 A7 FI935452 A7 FI 935452A7 FI 935452 A FI935452 A FI 935452A FI 935452 A FI935452 A FI 935452A FI 935452 A7 FI935452 A7 FI 935452A7
Authority
FI
Finland
Prior art keywords
hydroxyamidine
derivatives
hydroxyamidine derivatives
Prior art date
Application number
FI935452A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI935452A0 (fi
Inventor
Hongsuk Suh
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI935452A0 publication Critical patent/FI935452A0/fi
Publication of FI935452A7 publication Critical patent/FI935452A7/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
    • C07C259/18—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to carbon atoms of six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Lubricants (AREA)
FI935452A 1992-12-09 1993-12-03 Hydroksiamidiinijohdannaiset FI935452A7 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/987,856 US5455274A (en) 1992-12-09 1992-12-09 Hydroxyamidine derivatives

Publications (2)

Publication Number Publication Date
FI935452A0 FI935452A0 (fi) 1993-12-03
FI935452A7 true FI935452A7 (fi) 1994-06-10

Family

ID=25533631

Family Applications (1)

Application Number Title Priority Date Filing Date
FI935452A FI935452A7 (fi) 1992-12-09 1993-12-03 Hydroksiamidiinijohdannaiset

Country Status (19)

Country Link
US (1) US5455274A (OSRAM)
EP (1) EP0601977B1 (OSRAM)
JP (1) JPH06263710A (OSRAM)
KR (1) KR940014313A (OSRAM)
AT (1) ATE148103T1 (OSRAM)
AU (1) AU671683B2 (OSRAM)
CA (1) CA2110838A1 (OSRAM)
DE (1) DE69307669T2 (OSRAM)
DK (1) DK0601977T3 (OSRAM)
ES (1) ES2096265T3 (OSRAM)
FI (1) FI935452A7 (OSRAM)
GR (1) GR3022367T3 (OSRAM)
HU (1) HUT65778A (OSRAM)
IL (1) IL107842A (OSRAM)
NO (2) NO180300C (OSRAM)
NZ (1) NZ250379A (OSRAM)
PH (1) PH29931A (OSRAM)
TW (2) TW267999B (OSRAM)
ZA (1) ZA939193B (OSRAM)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995011014A1 (en) * 1993-10-21 1995-04-27 G.D. Searle & Co. Amidino derivatives useful as nitric oxide synthase inhibitors
DE4424713A1 (de) * 1994-07-13 1996-01-18 Boehringer Ingelheim Kg Substituierte Benzamidine, ihre Herstellung und Verwendung als Arnzneistoffe
JP2770769B2 (ja) * 1995-02-16 1998-07-02 日本メクトロン株式会社 ビスアミドキシム化合物、その製造法およびそれを含有する含フッ素エラストマー組成物
ID24720A (id) * 1997-12-12 2000-08-03 Novartis Ag Senyawa amidino tersubstitusi dalam perawatan penyakit gangguan paru-paru kronis
WO2000027199A1 (en) * 1998-11-12 2000-05-18 Eli Lilly And Company Aminobenzisoxazole compounds and libraries thereof
US7262223B2 (en) 2004-01-23 2007-08-28 Neurochem (International) Limited Amidine derivatives for treating amyloidosis
CA2554696C (en) 2004-02-13 2009-06-30 Warner-Lambert Company Llc Androgen receptor modulators
EP1737813A1 (en) 2004-04-13 2007-01-03 Warner-Lambert Company LLC Androgen modulators
WO2005102990A1 (en) * 2004-04-22 2005-11-03 Warner-Lambert Company Llc Androgen modulators
US8338648B2 (en) * 2004-06-12 2012-12-25 Signum Biosciences, Inc. Topical compositions and methods for epithelial-related conditions
CA2572898C (en) * 2004-07-05 2010-04-20 Dong Wha Pharmaceutical Ind. Co., Ltd. Composition for the prevention and treatment of allergic inflammatory disease
CA2570047C (en) 2004-07-08 2010-09-28 Warner-Lambert Company Llc 4-cycloalkoxy benzonitriles as androgen modulators
KR20060017929A (ko) 2004-08-04 2006-02-28 동화약품공업주식회사 티아졸 유도체가 치환된 신규한 벤즈아미딘 유도체, 그의제조방법 및 이를 유효성분으로 하는 약학 조성물
TW200724139A (en) 2005-05-05 2007-07-01 Warner Lambert Co Androgen modulators

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5922697B2 (ja) * 1976-01-13 1984-05-28 エーザイ株式会社 ビス−（メタ−アミジノフエノキシ）−化合物
NL7908922A (nl) * 1979-12-12 1981-07-16 Akzo Nv Carboximidamide derivaten.
US4324794A (en) * 1980-08-26 1982-04-13 Research Triangle Institute Inhibition of respiratory syncytial virus-induced cell fusion by amidino compounds
US4661505A (en) * 1982-11-03 1987-04-28 Eli Lilly And Company Leukotriene antagonists
CA1243322A (en) * 1984-01-23 1988-10-18 Joshua Rokach Antagonists of slow reacting substances of anaphylaxis
US4717736A (en) * 1984-01-23 1988-01-05 Merck Frosst Canada, Inc. Antagonists of slow reacting substances of anaphylaxis
DE3830054A1 (de) * 1988-09-03 1990-03-15 Boehringer Mannheim Gmbh Phenylamide - verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
US4963589A (en) * 1988-10-25 1990-10-16 The University Of North Carolina At Chapel Hill Methods for treating Giardia lamblia
US4933347A (en) * 1988-10-25 1990-06-12 University Of North Carolina At Chapel Hill Diamidines and bis(imidazolines) for the treatment of and prophylaxis against pneumocystis carinii pneumonia
US5162361A (en) * 1990-04-10 1992-11-10 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Method of treating diseases associated with elevated levels of interleukin 1
US5124350A (en) * 1990-06-28 1992-06-23 G. D. Searle & Co. Leukotriene b4 antagonists
CA2129526A1 (en) * 1992-02-05 1993-08-06 Franz Birke Novel amidine derivatives, their preparation and their use as medicaments with ltb4 antagonistic effect

Also Published As

Publication number Publication date
TW294651B (OSRAM) 1997-01-01
IL107842A (en) 1998-08-16
KR940014313A (ko) 1994-07-18
AU5218093A (en) 1994-06-23
NO934483L (no) 1994-06-10
TW267999B (OSRAM) 1996-01-11
NO180300B (no) 1996-12-16
DE69307669D1 (de) 1997-03-06
AU671683B2 (en) 1996-09-05
NZ250379A (en) 1995-12-21
NO180300C (no) 1997-03-26
PH29931A (en) 1996-09-16
US5455274A (en) 1995-10-03
ZA939193B (en) 1994-06-09
EP0601977A1 (en) 1994-06-15
GR3022367T3 (en) 1997-04-30
JPH06263710A (ja) 1994-09-20
ATE148103T1 (de) 1997-02-15
DK0601977T3 (da) 1997-02-10
EP0601977B1 (en) 1997-01-22
IL107842A0 (en) 1994-04-12
HUT65778A (en) 1994-07-28
NO934483D0 (no) 1993-12-08
ES2096265T3 (es) 1997-03-01
FI935452A0 (fi) 1993-12-03
CA2110838A1 (en) 1994-06-10
HU9303501D0 (en) 1994-04-28
DE69307669T2 (de) 1997-11-13

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Owner name: NOVARTIS AG