FI932596A0 - 7-Substituerad-6-fluor-1,4-dihydro-oxokinolin-3-karboxylsyrafoereningar anvaendbara som antibakteriska aemnen - Google Patents

7-Substituerad-6-fluor-1,4-dihydro-oxokinolin-3-karboxylsyrafoereningar anvaendbara som antibakteriska aemnen

Info

Publication number
FI932596A0
FI932596A0 FI932596A FI932596A FI932596A0 FI 932596 A0 FI932596 A0 FI 932596A0 FI 932596 A FI932596 A FI 932596A FI 932596 A FI932596 A FI 932596A FI 932596 A0 FI932596 A0 FI 932596A0
Authority
FI
Finland
Prior art keywords
group
substituted
dihydro
oxoquinoline
fluoro
Prior art date
Application number
FI932596A
Other languages
English (en)
Other versions
FI932596A (fi
Inventor
Rajeshwar Singh
Inder Pal Singh
George Thomas
Maya Prakash Singh
Ronald George Micetich
Rakhshandeh Fathi-Afshar
Thomas Roger Doerksen
Original Assignee
Synphar Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synphar Lab Inc filed Critical Synphar Lab Inc
Publication of FI932596A0 publication Critical patent/FI932596A0/fi
Publication of FI932596A publication Critical patent/FI932596A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI932596A 1990-12-05 1993-06-07 7-substituerad-6-fluor-1,4-dihydro-oxokinolin-3-karboxylsyrafoereningar anvaendbara som antibakteriska aemnen FI932596A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62171690A 1990-12-05 1990-12-05
PCT/CA1991/000435 WO1992010492A1 (en) 1990-12-05 1991-12-05 7-substituted-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid compounds useful as antibacterial agents

Publications (2)

Publication Number Publication Date
FI932596A0 true FI932596A0 (fi) 1993-06-07
FI932596A FI932596A (fi) 1993-08-04

Family

ID=24491336

Family Applications (1)

Application Number Title Priority Date Filing Date
FI932596A FI932596A (fi) 1990-12-05 1993-06-07 7-substituerad-6-fluor-1,4-dihydro-oxokinolin-3-karboxylsyrafoereningar anvaendbara som antibakteriska aemnen

Country Status (12)

Country Link
EP (1) EP0561850B1 (fi)
JP (1) JPH06507149A (fi)
KR (1) KR100196440B1 (fi)
AT (1) ATE194612T1 (fi)
CA (1) CA2099591C (fi)
DE (1) DE69132314T2 (fi)
FI (1) FI932596A (fi)
HU (2) HUT64058A (fi)
NO (1) NO305479B1 (fi)
NZ (1) NZ240883A (fi)
WO (1) WO1992010492A1 (fi)
ZA (1) ZA919601B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5342846A (en) * 1990-12-05 1994-08-30 Synphar Laboratories, Inc. 7-substituted-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid compounds and 7-(substituted triazolyl pyrrolidin-1-yl) 4-oxoquinoline-3-carboxylic acid derivatives useful as antibacterial agents
US5221676A (en) * 1992-02-06 1993-06-22 Warner-Lambert Company 7-substituted quinolones and naphthyridones as antibacterial agents
KR960003616B1 (ko) * 1992-07-23 1996-03-20 재단법인 한국화학연구소 우수한 항균작용을 갖는 신규한 피리돈 카르복실산 유도체 및 그의 제조방법
TW252107B (fi) * 1993-08-27 1995-07-21 Hokuriku Pharmacetical Co Ltd
WO1996022988A1 (fr) * 1995-01-24 1996-08-01 Hokuriku Seiyaku Co., Ltd. Derives de l'acide quiloleine carboxylique
DE60000833T2 (de) * 1999-06-02 2003-09-18 Warner-Lambert Co., Morris Plains Amino-heterocyclen zur verwendung als pharmazeutische mittel
US6821969B2 (en) 2001-02-13 2004-11-23 Pharmacia & Upjohn Company Thioxazinoquinolones as antiviral agents
AU2012256237B2 (en) 2011-05-13 2017-01-05 Array Biopharma Inc. Pyrrolidinyl urea and pyrrolidinyl thiourea compounds as TrkA kinase inhibitors
KR101996697B1 (ko) 2011-08-31 2019-07-04 오쓰까 세이야꾸 가부시키가이샤 퀴놀론 화합물
JP6577479B2 (ja) * 2014-02-27 2019-09-18 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung Nav チャンネル阻害剤としてのヘテロ環化合物及びその使用
GB201708606D0 (en) 2017-05-30 2017-07-12 King S College London Antibiotic resistance breakers
WO2020113094A1 (en) 2018-11-30 2020-06-04 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE58742B1 (en) * 1984-07-20 1993-11-05 Warner Lambert Co Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds
DE3519286A1 (de) * 1985-05-30 1986-12-04 Bayer Ag, 5090 Leverkusen 7-azolyl-1-cyclopropyl-1,4-dihydro-4-oxo-3- chinolincarbonsaeuren und -1,8-naphthyridin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
AU5123690A (en) * 1989-03-13 1990-09-13 Bristol-Myers Squibb Company 5-substituted-1,4-dihydro-4-oxo-nephthyridine-3-carboxylate antibacterial agents
NO177302C (no) * 1989-03-16 1995-08-23 Esteve Labor Dr Analogifremgangsmåte til fremstilling av terapeutisk aktive substituerte azetidinylkinolon(naftyridon)karboksylsyrederivater

Also Published As

Publication number Publication date
EP0561850A1 (en) 1993-09-29
WO1992010492A1 (en) 1992-06-25
AU666296B2 (en) 1996-02-08
JPH06507149A (ja) 1994-08-11
ZA919601B (en) 1992-10-28
DE69132314D1 (de) 2000-08-17
AU9021091A (en) 1992-07-08
NZ240883A (en) 1994-09-27
HUT64058A (en) 1993-11-29
NO932033L (no) 1993-06-03
FI932596A (fi) 1993-08-04
KR100196440B1 (ko) 1999-06-15
NO932033D0 (no) 1993-06-03
EP0561850B1 (en) 2000-07-12
HU9301648D0 (en) 1993-09-28
CA2099591A1 (en) 1992-06-06
DE69132314T2 (de) 2000-12-14
NO305479B1 (no) 1999-06-07
CA2099591C (en) 2002-11-12
ATE194612T1 (de) 2000-07-15

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