ES2040366T3 - Procedimiento de preparacion de nuevos derivados de 1-(bencilpiperidino)2-propanol. - Google Patents

Procedimiento de preparacion de nuevos derivados de 1-(bencilpiperidino)2-propanol.

Info

Publication number
ES2040366T3
ES2040366T3 ES198888402320T ES88402320T ES2040366T3 ES 2040366 T3 ES2040366 T3 ES 2040366T3 ES 198888402320 T ES198888402320 T ES 198888402320T ES 88402320 T ES88402320 T ES 88402320T ES 2040366 T3 ES2040366 T3 ES 2040366T3
Authority
ES
Spain
Prior art keywords
substituted
group
procedure
preparation
halogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888402320T
Other languages
English (en)
Inventor
Didier Van Broeck
Madeleine Mosse
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Application granted granted Critical
Publication of ES2040366T3 publication Critical patent/ES2040366T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B2/00—Preservation of foods or foodstuffs, in general
    • A23B2/70—Preservation of foods or foodstuffs, in general by treatment with chemicals
    • A23B2/725—Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
    • A23B2/729—Organic compounds; Microorganisms; Enzymes
    • A23B2/771—Organic compounds containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/524—Preservatives

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)

Abstract

LA INVENCION SE REFIERE A COMPUESTOS DE FORMULA(I) EN LA QUE AR ES UN GRUPO FENILO SUSTITUIDO POR R2, R3 Y R4 O UN GRUPO NAFTILO - 1 O NAFTILO - 2, NO SUSTITUIDO O SUSTITUIDOS POR 1 O 2 ATOMOS DE HALOGENO; X ES UN ATOMO DE OXIGENO O DE AZUFRE; R1 ES H O UN ATOMO DE HALOGENO; R2 ES UN ATOMO DE HALOGENO, UN GRUPO TRIFLUOROMETILO, UN GRUPO FENILO NO SUSTITUIDO O SUSTITUIDO POR 1 A 3 ATOMOS DE HALOGENO, UN GRUPO BENCILO NO SUSTITUIDO O SUSTITUIDO POR 1 A 3 ATOMOS DE HALOGENO, UN GRUPO FENOXI NO SUSTITUIDO O SUSTITUIDO POR 1 A 3 ATOMOS DE HALOGENO O UN GRUPO ALQUILO C1 - C4; PROCEDIMIENTO DE PREPARACION DE DICHOS COMPUESTOS Y SU UTILIZACION COMO ANTIMICROBIANOS ANTISEPTICOS, DESINFECTANTES Y CONSERVANTES EN DIFERENTES TIPOS DE PRODUCTOS.
ES198888402320T 1987-09-17 1988-09-15 Procedimiento de preparacion de nuevos derivados de 1-(bencilpiperidino)2-propanol. Expired - Lifetime ES2040366T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8712885A FR2620704B1 (fr) 1987-09-17 1987-09-17 Derives de (benzyl-4 piperidino)-1 propanol-2, leur preparation, leur utilisation comme antimicrobiens et les produits les contenant

Publications (1)

Publication Number Publication Date
ES2040366T3 true ES2040366T3 (es) 1993-10-16

Family

ID=9354986

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888402320T Expired - Lifetime ES2040366T3 (es) 1987-09-17 1988-09-15 Procedimiento de preparacion de nuevos derivados de 1-(bencilpiperidino)2-propanol.

Country Status (18)

Country Link
US (1) US5036077A (es)
EP (1) EP0308328B1 (es)
JP (1) JPH01102062A (es)
AT (1) ATE70054T1 (es)
AU (1) AU608649B2 (es)
DE (1) DE3866652D1 (es)
DK (1) DK519788A (es)
ES (1) ES2040366T3 (es)
FR (1) FR2620704B1 (es)
GR (1) GR3003597T3 (es)
HK (1) HK16493A (es)
IL (1) IL87777A0 (es)
MA (1) MA21379A1 (es)
NZ (1) NZ226201A (es)
OA (1) OA09015A (es)
PT (1) PT88503B (es)
TN (1) TNSN88093A1 (es)
ZA (1) ZA886936B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR245888A1 (es) * 1989-01-23 1994-03-30 Merrell Pharma Inc Procedimiento para la preparacion de una composicion farmaceutica liquida de derivados de piperidinoalcanol.
FR2663329B1 (fr) * 1990-06-15 1992-10-16 Sanofi Sa Composes aromatiques amines, procede pour leur preparation et compositions pharmaceutiques les contenant.
FI97540C (fi) * 1989-11-06 1997-01-10 Sanofi Sa Menetelmä terapeuttisesti käyttökelpoisten, aromaattisesti substituoitujen piperidiini- ja piperatsiinijohdannaisten valmistamiseksi
US5549888A (en) * 1994-01-31 1996-08-27 Procter & Gamble Aqueous topical anti-acne compositions of low pH
FR2738567B1 (fr) * 1995-09-08 1997-10-17 Synthelabo Derives de alpha-phenylpiperidine-1-propanol, leur preparation et leur application en therapeutique
ZA9610741B (en) 1995-12-22 1997-06-24 Warner Lambert Co 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610736B (en) 1995-12-22 1997-06-27 Warner Lambert Co 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists
ZA9610738B (en) 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
ZA9610745B (en) * 1995-12-22 1997-06-24 Warner Lambert Co 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists
FR2780057B1 (fr) * 1998-06-18 2002-09-13 Sanofi Sa Phenoxypropanolamines, procede pour leur preparation et compositions pharmaceutiques les contenant
CA2450073C (en) 2001-07-25 2017-08-29 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
US20060193804A1 (en) * 2005-02-24 2006-08-31 L'oreal Haircare use of cyclic amine derivatives
EP2671508B1 (en) 2005-04-28 2020-09-16 Proteus Digital Health, Inc. Pharma-informatics system
JP2010503710A (ja) 2006-09-18 2010-02-04 ラプトール ファーマシューティカル インコーポレイテッド 受容体関連タンパク質（ｒａｐ）結合体の投与による肝障害の処置
EP2348831A2 (en) * 2008-10-10 2011-08-03 Ndsu Research Foundation Antimicrobial compositions
WO2010042804A2 (en) * 2008-10-10 2010-04-15 Ndsu Research Foundation Zwitterionic/amphiphilic pentablock copolymers and coatings therefrom
ES2919563T3 (es) 2009-02-20 2022-07-27 Enhanx Biopharm Inc Sistema de administración de medicamentos a base de glutatión
KR20180114970A (ko) 2009-05-06 2018-10-19 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
US20110171279A1 (en) * 2009-11-02 2011-07-14 Ndsu Research Foundation Polyethylenimine biocides
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1190770A (en) * 1966-08-23 1970-05-06 Rech S Et D Applic Scient Et M Improvements in or relating to Piperidine Derivatives
LU66207A1 (es) * 1972-09-29 1974-04-02
US3912733A (en) * 1974-05-08 1975-10-14 American Home Prod 1-Substituted -6-(2-hydroxy-3-substituted aminopropoxy)xanthen-9-ones
DE3034237A1 (de) * 1979-09-18 1981-04-16 Otsuka Pharmaceutical Co. Ltd., Tokyo Carbostyrilderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende, antihistaminisch wirkende mittel
EP0222694A3 (de) * 1985-09-13 1987-08-26 Ciba-Geigy Ag Mikrobizide
DE3627071A1 (de) * 1986-08-09 1988-02-11 Bayer Ag Substituierte hydroxypropylamin-derivate

Also Published As

Publication number Publication date
EP0308328A1 (fr) 1989-03-22
US5036077A (en) 1991-07-30
MA21379A1 (fr) 1989-04-01
ATE70054T1 (de) 1991-12-15
IL87777A0 (en) 1989-03-31
PT88503B (pt) 1992-11-30
PT88503A (pt) 1988-10-01
OA09015A (fr) 1991-03-31
EP0308328B1 (fr) 1991-12-04
HK16493A (en) 1993-03-12
AU2229688A (en) 1989-03-23
NZ226201A (en) 1991-06-25
JPH01102062A (ja) 1989-04-19
DE3866652D1 (de) 1992-01-16
DK519788D0 (da) 1988-09-16
TNSN88093A1 (fr) 1990-07-10
AU608649B2 (en) 1991-04-11
GR3003597T3 (es) 1993-03-16
FR2620704A1 (fr) 1989-03-24
DK519788A (da) 1989-03-18
FR2620704B1 (fr) 1991-04-26
ZA886936B (en) 1989-05-30

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