FI931014A - 2-hydroxi- och 2-acyloxi-4-morfolinylantracykliner - Google Patents
2-hydroxi- och 2-acyloxi-4-morfolinylantracykliner Download PDFInfo
- Publication number
- FI931014A FI931014A FI931014A FI931014A FI931014A FI 931014 A FI931014 A FI 931014A FI 931014 A FI931014 A FI 931014A FI 931014 A FI931014 A FI 931014A FI 931014 A FI931014 A FI 931014A
- Authority
- FI
- Finland
- Prior art keywords
- hydrogen
- morpholinylantracycliner
- acyloxi
- hydroxi
- och
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB909019934A GB9019934D0 (en) | 1990-09-12 | 1990-09-12 | 2-hydroxy-and 2-acyloxy-4-morpholinyl anthracyclines |
PCT/EP1991/001506 WO1992004362A1 (en) | 1990-09-12 | 1991-08-08 | 2-hydroxy- and 2-acyloxy-4-morpholinyl anthracyclines |
Publications (2)
Publication Number | Publication Date |
---|---|
FI931014A true FI931014A (fi) | 1993-03-08 |
FI931014A0 FI931014A0 (fi) | 1993-03-08 |
Family
ID=10682083
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI931014A FI931014A0 (fi) | 1990-09-12 | 1993-03-08 | 2-hydroxi- och 2-acyloxi-4-morfolinylantracykliner |
Country Status (13)
Country | Link |
---|---|
US (1) | US5510469A (fi) |
EP (1) | EP0475071B1 (fi) |
JP (1) | JPH06500770A (fi) |
KR (1) | KR930702367A (fi) |
AT (1) | ATE116655T1 (fi) |
AU (1) | AU8324591A (fi) |
CA (1) | CA2088979A1 (fi) |
DE (1) | DE69106459T2 (fi) |
ES (1) | ES2070376T3 (fi) |
FI (1) | FI931014A0 (fi) |
GB (1) | GB9019934D0 (fi) |
HU (1) | HUT63850A (fi) |
WO (1) | WO1992004362A1 (fi) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100420007B1 (ko) * | 2001-04-25 | 2004-03-02 | 노영쇠 | 안트라사이클린 유도체 및 이를 포함하는 항암제 |
US7053191B2 (en) * | 2003-05-21 | 2006-05-30 | Solux Corporation | Method of preparing 4-R-substituted 4-demethoxydaunorubicin |
US20070103314A1 (en) * | 2004-11-17 | 2007-05-10 | Geissler Randolph K | Radio frequency animal tracking system |
US8357785B2 (en) * | 2008-01-08 | 2013-01-22 | Solux Corporation | Method of aralkylation of 4′-hydroxyl group of anthracylins |
US8846882B2 (en) | 2011-04-29 | 2014-09-30 | Synbias Pharma Ag | Method of producing 4-demethoxydaunorubicin |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4438105A (en) * | 1982-04-19 | 1984-03-20 | Farmaitalia Carlo Erba S.P.A | 4'-Iododerivatives of anthracycline glycosides |
US4772688A (en) * | 1982-12-20 | 1988-09-20 | Ohio State University Research Foundation | 14-acyloxy-2'-halo-anthracycline anti-cancer antibiotics |
US4710564A (en) * | 1985-01-18 | 1987-12-01 | Microbial Chemistry Research Foundation | Anthracycline compounds |
GB2172594B (en) * | 1985-03-22 | 1988-06-08 | Erba Farmitalia | New morpholino derivatives of daunorubicin and doxorubicin |
GB8508079D0 (en) * | 1985-03-28 | 1985-05-01 | Erba Farmitalia | Antitumor anthracyclines |
GB8617742D0 (en) * | 1986-07-21 | 1986-08-28 | Erba Farmitalia | 6-amino anthracyclines |
GB2196626B (en) * | 1986-10-15 | 1990-09-19 | Erba Farmitalia | Antitumor anthracycline glycosides, their preparation, intermediates thereof, and compositions and use therefor |
NZ224252A (en) * | 1987-04-21 | 1991-09-25 | Erba Carlo Spa | An anthracycline glycoside and its preparation |
GB2212154B (en) * | 1987-11-10 | 1991-03-27 | Erba Carlo Spa | New 4-demethoxy anthracycline derivatives |
GB8803076D0 (en) * | 1988-02-10 | 1988-03-09 | Erba Carlo Spa | 3'-deamino-4'-deoxy-4'-amino anthracyclines |
GB8818167D0 (en) * | 1988-07-29 | 1988-09-01 | Erba Carlo Spa | Novel 4-substituted anthracyclinones & process for their preparation |
JPH0269494A (ja) * | 1988-09-02 | 1990-03-08 | Kirin Brewery Co Ltd | 3′‐デアミノ‐3′‐(2″‐置換‐4″‐モルフォリノ)‐アンスラサイクリン化合物およびその使用 |
US5138044A (en) * | 1990-08-13 | 1992-08-11 | Glycomed, Inc. | Synthesis of sialosides |
-
1990
- 1990-09-12 GB GB909019934A patent/GB9019934D0/en active Pending
-
1991
- 1991-08-06 ES ES91113170T patent/ES2070376T3/es not_active Expired - Lifetime
- 1991-08-06 AT AT91113170T patent/ATE116655T1/de not_active IP Right Cessation
- 1991-08-06 EP EP91113170A patent/EP0475071B1/en not_active Expired - Lifetime
- 1991-08-06 DE DE69106459T patent/DE69106459T2/de not_active Expired - Fee Related
- 1991-08-08 KR KR1019930700737A patent/KR930702367A/ko not_active Application Discontinuation
- 1991-08-08 AU AU83245/91A patent/AU8324591A/en not_active Abandoned
- 1991-08-08 WO PCT/EP1991/001506 patent/WO1992004362A1/en active Application Filing
- 1991-08-08 HU HU93724A patent/HUT63850A/hu unknown
- 1991-08-08 CA CA002088979A patent/CA2088979A1/en not_active Abandoned
- 1991-08-08 JP JP3513863A patent/JPH06500770A/ja active Pending
- 1991-08-08 US US07/987,281 patent/US5510469A/en not_active Expired - Fee Related
-
1993
- 1993-03-08 FI FI931014A patent/FI931014A0/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DE69106459T2 (de) | 1995-05-18 |
US5510469A (en) | 1996-04-23 |
KR930702367A (ko) | 1993-09-08 |
DE69106459D1 (de) | 1995-02-16 |
CA2088979A1 (en) | 1992-03-13 |
JPH06500770A (ja) | 1994-01-27 |
HUT63850A (en) | 1993-10-28 |
EP0475071B1 (en) | 1995-01-04 |
FI931014A0 (fi) | 1993-03-08 |
HU9300724D0 (en) | 1993-06-28 |
WO1992004362A1 (en) | 1992-03-19 |
AU8324591A (en) | 1992-03-30 |
EP0475071A1 (en) | 1992-03-18 |
ES2070376T3 (es) | 1995-06-01 |
GB9019934D0 (en) | 1990-10-24 |
ATE116655T1 (de) | 1995-01-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application lapsed |