FI925731A0 - Polycykliska guaninderivat - Google Patents
Polycykliska guaninderivatInfo
- Publication number
- FI925731A0 FI925731A0 FI925731A FI925731A FI925731A0 FI 925731 A0 FI925731 A0 FI 925731A0 FI 925731 A FI925731 A FI 925731A FI 925731 A FI925731 A FI 925731A FI 925731 A0 FI925731 A0 FI 925731A0
- Authority
- FI
- Finland
- Prior art keywords
- aryl
- alkyl
- heteroaryl
- hydrogen
- pct
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 8
- 125000003118 aryl group Chemical group 0.000 abstract 6
- 125000001072 heteroaryl group Chemical group 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 150000002431 hydrogen Chemical group 0.000 abstract 4
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 3
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000005122 aminoalkylamino group Chemical group 0.000 abstract 1
- 125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 230000003182 bronchodilatating effect Effects 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- UYTPUPDQBNUYGX-UHFFFAOYSA-N guanine Chemical class O=C1NC(N)=NC2=C1N=CN2 UYTPUPDQBNUYGX-UHFFFAOYSA-N 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 125000005191 hydroxyalkylamino group Chemical group 0.000 abstract 1
- -1 monoalkylamino Chemical group 0.000 abstract 1
- 239000003158 myorelaxant agent Substances 0.000 abstract 1
- 229910052717 sulfur Chemical group 0.000 abstract 1
- 239000011593 sulfur Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Filtering Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US54156890A | 1990-06-21 | 1990-06-21 | |
PCT/US1991/004154 WO1991019717A1 (en) | 1990-06-21 | 1991-06-20 | Polycyclic guanine derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
FI925731A0 true FI925731A0 (fi) | 1992-12-17 |
FI925731A7 FI925731A7 (fi) | 1992-12-17 |
Family
ID=24160139
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI925731A FI925731A7 (fi) | 1990-06-21 | 1992-12-17 | Polycykliska guaninderivat |
Country Status (21)
Country | Link |
---|---|
US (1) | US5393755A (cs) |
EP (1) | EP0538332B1 (cs) |
JP (1) | JPH0747589B2 (cs) |
KR (1) | KR960004532B1 (cs) |
AT (1) | ATE155786T1 (cs) |
AU (1) | AU651607B2 (cs) |
CA (1) | CA2085733C (cs) |
CZ (1) | CZ281920B6 (cs) |
DE (1) | DE69126980T2 (cs) |
FI (1) | FI925731A7 (cs) |
HU (1) | HUT65623A (cs) |
IE (1) | IE912126A1 (cs) |
IL (1) | IL98559A0 (cs) |
NO (1) | NO924940D0 (cs) |
NZ (1) | NZ238609A (cs) |
OA (1) | OA09723A (cs) |
PL (1) | PL169481B1 (cs) |
RU (1) | RU2080322C1 (cs) |
TW (1) | TW197441B (cs) |
WO (1) | WO1991019717A1 (cs) |
ZA (1) | ZA914727B (cs) |
Families Citing this family (78)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW270118B (cs) * | 1993-02-26 | 1996-02-11 | Schering Corp | |
US5929046A (en) * | 1994-06-08 | 1999-07-27 | Cancer Research Campaign Technology Limited | Pyrimidine and purine derivatives and their use in treating tumour cells |
US5661153A (en) * | 1994-07-19 | 1997-08-26 | Japan Energy Corporation | 1-arylpyrimidine derivatives and pharmaceutical use thereof |
AR004752A1 (es) * | 1995-11-28 | 1999-03-10 | Schering Corp | 2'-[[4'-halo-[1,1'-bifenil]-4-il]metil]-5'-metil-espiro[ciclopentano-1,7' (8'h)-[3h imidazo[2,1-b]purin]-4'(5'h)-onas, uso del mismo para la preparacionde un medicamento, composicion farmaceutica y un proceso para su preparacion. |
US5824683A (en) * | 1995-11-28 | 1998-10-20 | Schering Corporation | 2'- 4'-halo- 1,1'-biphenyl!-4-yl!methyl!-5'-methyl-spiro cyclopentane-1,7' (8'H)- 3H! imidazo 2,1-b!purin!-4' (5'H)-ones |
CA2238283C (en) * | 1997-05-30 | 2002-08-20 | Cell Pathways, Inc. | Method for identifying compounds for inhibition of neoplastic lesions, pharmaceutical compositions from such compounds and uses of such compounds and compositions for treating neoplastic lesions |
US5858694A (en) * | 1997-05-30 | 1999-01-12 | Cell Pathways, Inc. | Method for identifying compounds for inhibition of cancerous lesions |
US6410584B1 (en) * | 1998-01-14 | 2002-06-25 | Cell Pathways, Inc. | Method for inhibiting neoplastic cells with indole derivatives |
US6200771B1 (en) | 1998-10-15 | 2001-03-13 | Cell Pathways, Inc. | Method of using a novel phosphodiesterase in pharmaceutical screeing to identify compounds for treatment of neoplasia |
US6130053A (en) * | 1999-08-03 | 2000-10-10 | Cell Pathways, Inc. | Method for selecting compounds for inhibition of neoplastic lesions |
US6133271A (en) * | 1998-11-19 | 2000-10-17 | Cell Pathways, Inc. | Method for inhibiting neoplastic cells and related conditions by exposure thienopyrimidine derivatives |
US6187779B1 (en) | 1998-11-20 | 2001-02-13 | Cell Pathways, Inc. | Method for inhibiting neoplastic cells and related conditions by exposure to 2,8-disubstituted quinazoline derivatives |
US6369092B1 (en) | 1998-11-23 | 2002-04-09 | Cell Pathways, Inc. | Method for treating neoplasia by exposure to substituted benzimidazole derivatives |
US6486155B1 (en) | 1998-11-24 | 2002-11-26 | Cell Pathways Inc | Method of inhibiting neoplastic cells with isoquinoline derivatives |
US6034099A (en) * | 1998-11-24 | 2000-03-07 | Cell Pathways, Inc. | Method for inhibiting neoplastic lesions by administering 4-(arylmethylene)- 2, 3- dihydro-pyrazol-3-ones |
US6077842A (en) * | 1998-11-24 | 2000-06-20 | Cell Pathways, Inc. | Method of inhibiting neoplastic cells with pyrazolopyridylpyridazinone derivatives |
US6025394A (en) | 1999-01-29 | 2000-02-15 | Cell Pathways, Inc. | Method for treating patients with acne by administering substituted sulfonyl indenyl acetic acids, amides and alcohols |
US6020379A (en) * | 1999-02-19 | 2000-02-01 | Cell Pathways, Inc. | Position 7 substituted indenyl-3-acetic acid derivatives and amides thereof for the treatment of neoplasia |
ES2166270B1 (es) * | 1999-07-27 | 2003-04-01 | Almirall Prodesfarma Sa | Derivados de 8-fenil-6,9-dihidro-(1,2,4,)triazolo(3,4-i)purin-5-ona. |
US6555547B1 (en) | 2000-02-28 | 2003-04-29 | Cell Pathways, Inc. | Method for treating a patient with neoplasia by treatment with a vinca alkaloid derivative |
US6569638B1 (en) | 2000-03-03 | 2003-05-27 | Cell Pathways, Inc | Method for screening compounds for the treatment of neoplasia |
US6821978B2 (en) * | 2000-09-19 | 2004-11-23 | Schering Corporation | Xanthine phosphodiesterase V inhibitors |
EP1790652A1 (en) * | 2001-08-28 | 2007-05-30 | Schering Corporation | Polycyclic guanine phosphodiesterase V inhibitors |
JP4450365B2 (ja) * | 2001-08-28 | 2010-04-14 | シェーリング コーポレイション | 多環式グアニンホスホジエステラーゼv阻害剤 |
US20030211040A1 (en) | 2001-08-31 | 2003-11-13 | Paul Greengard | Phosphodiesterase activity and regulation of phosphodiesterase 1B-mediated signaling in brain |
EP1312363A1 (en) * | 2001-09-28 | 2003-05-21 | Pfizer Products Inc. | Methods of treatment and kits comprising a growth hormone secretagogue |
US6943171B2 (en) * | 2001-11-09 | 2005-09-13 | Schering Corporation | Polycyclic guanine derivative phosphodiesterase V inhibitors |
US7342884B2 (en) * | 2002-03-13 | 2008-03-11 | Harmonic, Inc. | Method and apparatus for one directional communications in bidirectional communications channel |
US7074923B2 (en) * | 2002-05-31 | 2006-07-11 | Schering Corporation | Process for preparing xanthine phosphodiesterase V inhibitors and precursors thereof |
EP1719772A1 (en) | 2002-05-31 | 2006-11-08 | Schering Corporation | Process for preparing xanthine phosphodiesterase v inhibitors and precursors thereof |
WO2005012303A1 (en) * | 2003-07-31 | 2005-02-10 | Schering Corporation | Metabolite of xanthine phosphodiesterase 5 inhibitor and derivatives thereof useful for treatment of erectile dysfunction |
AU2004260758B2 (en) * | 2003-08-01 | 2007-06-07 | Nippon Soda Co., Ltd. | Phenylazole compounds, production process, and antioxidants |
EP1691788A2 (en) * | 2003-11-21 | 2006-08-23 | Schering Corporation | Phosphodiesterase v inhibitor formulations |
WO2006104870A2 (en) * | 2005-03-25 | 2006-10-05 | Schering Corporation | Methods of treating benign prostatic hyperplasia or lower urinary track symptoms by using pde 5 inhibitors |
CA2611312C (en) | 2005-06-06 | 2013-12-03 | Intra-Cellular Therapies, Inc. | Organic compounds |
WO2007025103A2 (en) * | 2005-08-23 | 2007-03-01 | Intra-Cellular Therapies, Inc. | Organic compounds for treating reduced dopamine receptor signalling activity |
WO2007055170A1 (ja) * | 2005-11-09 | 2007-05-18 | Tosoh Corporation | パーフルオロアルキル基を有する核酸塩基類およびその製造方法 |
GB0601951D0 (en) | 2006-01-31 | 2006-03-15 | Novartis Ag | Organic compounds |
EP2023729B1 (en) | 2006-06-06 | 2016-05-04 | Intra-Cellular Therapies, Inc. | Organic compounds |
US9198924B2 (en) * | 2006-11-13 | 2015-12-01 | Intra-Cellular Therapies, Inc. | Organic compounds |
WO2008070095A1 (en) | 2006-12-05 | 2008-06-12 | Intra-Cellular Therapies, Inc. | Novel uses |
US8349858B2 (en) * | 2007-06-21 | 2013-01-08 | Merck Sharp & Dohme | Polycyclic guanine derivatives and use thereof |
PL2240490T3 (pl) | 2007-12-06 | 2014-02-28 | Takeda Pharmaceuticals Co | Związki organiczne |
KR20100094551A (ko) | 2007-12-06 | 2010-08-26 | 인트라-셀룰라 써래피스, 인코퍼레이티드. | 유기 화합물 |
CA2740394A1 (en) | 2008-12-06 | 2010-06-10 | Intra-Cellular Therapies, Inc. | Organic compounds |
US8697710B2 (en) | 2008-12-06 | 2014-04-15 | Intra-Cellular Therapies, Inc. | Optionally substituted 3-amino-4-(thioxo or imino)-4,5-dihydro-2H-pyrazolo [3,4-d]pyrimidin-6(7H)-ones |
EA201170770A1 (ru) | 2008-12-06 | 2012-02-28 | Интра-Селлулар Терапиз, Инк. | Органические соединения |
US8664207B2 (en) * | 2008-12-06 | 2014-03-04 | Intra-Cellular Therapies, Inc. | Organic compounds |
ES2580759T3 (es) | 2008-12-06 | 2016-08-26 | Intra-Cellular Therapies, Inc. | Compuestos orgánicos |
EP2367430B1 (en) | 2008-12-06 | 2014-08-13 | Intra-Cellular Therapies, Inc. | Organic compounds |
EP2400970A4 (en) | 2009-02-25 | 2012-07-18 | Intra Cellular Therapies Inc | PDE-1-HEMMER FOR EYE DRESSING |
EP2405917B1 (en) | 2009-03-13 | 2014-04-23 | Advinus Therapeutics Private Limited | Substituted fused pyrimidine compounds |
JP2012526810A (ja) | 2009-05-13 | 2012-11-01 | イントラ−セルラー・セラピーズ・インコーポレイテッド | 有機化合物 |
WO2011016861A2 (en) | 2009-08-05 | 2011-02-10 | Intra-Cellular Therapies, Inc. | Novel regulatory proteins and inhibitors |
US20110190192A1 (en) * | 2009-12-15 | 2011-08-04 | Cebix Inc. | Methods for treating erectile dysfunction in patients with insulin-dependent diabetes |
EP2575817A4 (en) | 2010-05-31 | 2014-01-08 | Intra Cellular Therapies Inc | ORGANIC CONNECTIONS |
JP5894148B2 (ja) | 2010-05-31 | 2016-03-23 | イントラ−セルラー・セラピーズ・インコーポレイテッドIntra−Cellular Therapies, Inc. | 有機化合物 |
TW201206937A (en) | 2010-05-31 | 2012-02-16 | Intra Cellular Therapies Inc | Organic compounds |
WO2011153138A1 (en) | 2010-05-31 | 2011-12-08 | Intra-Cellular Therapies, Inc. | Organic compounds |
US10561656B2 (en) | 2011-06-10 | 2020-02-18 | Intra-Cellular Therapies, Inc. | Organic compounds |
WO2014127331A1 (en) | 2013-02-17 | 2014-08-21 | Intra-Cellular Therapies, Inc. | Novel uses |
EP3479825B1 (en) | 2013-03-15 | 2021-02-17 | Intra-Cellular Therapies, Inc. | Pde1 inhibitors for use in the treatment and/or prevention of cns or pns diseases or disorders |
PL2970279T3 (pl) | 2013-03-15 | 2021-05-31 | Intra-Cellular Therapies, Inc. | Związki organiczne |
EP3091983B1 (en) | 2014-01-08 | 2019-10-02 | Intra-Cellular Therapies, Inc. | Pharmaceutical compositions comprising a pde-1 inhibitor and a pde-2 inhibitor |
JP6810613B2 (ja) | 2014-06-20 | 2021-01-06 | イントラ−セルラー・セラピーズ・インコーポレイテッドIntra−Cellular Therapies, Inc. | 有機化合物 |
US10285992B2 (en) | 2014-08-07 | 2019-05-14 | Intra-Cellular Therapies, Inc. | Combinations of PDE1 inhibitors and NEP inhibitors and associated methods |
US9546175B2 (en) | 2014-08-07 | 2017-01-17 | Intra-Cellular Therapies, Inc. | Organic compounds |
EP3177627B1 (en) | 2014-08-07 | 2019-07-24 | Intra-Cellular Therapies, Inc. | Imidazo[1,2-a]-pyrazolo[4,3-e]-pyrimidin-4-one derivatives with pde1 inhibiting activity |
IL292225B2 (en) | 2014-09-17 | 2024-12-01 | Intra Cellular Therapies Inc | Derivatives of 5,7,7-trimethyl-[2H]-imidazo-[1,2-a]pyrazolo[4,3-e]pyrimidin-4(5H)-one and pharmaceutical compositions comprising them. |
RU2702732C1 (ru) | 2014-12-06 | 2019-10-10 | Интра-Селлулар Терапиз, Инк. | Органические соединения |
CA2969594A1 (en) | 2014-12-06 | 2016-06-09 | Intra-Cellular Therapies, Inc. | Pde2 inhibiting organic compounds |
EP3436083A4 (en) | 2016-03-28 | 2019-11-27 | Intra-Cellular Therapies, Inc. | NOVEL COMPOSITIONS AND METHOD |
EP3509589B1 (en) | 2016-09-12 | 2021-11-17 | Intra-Cellular Therapies, Inc. | Novel uses |
CA3047408A1 (en) | 2016-12-28 | 2018-07-05 | Dart Neuroscience, Llc | Substituted pyrazolopyrimidinone compounds as pde2 inhibitors |
EP3717488B1 (en) | 2017-11-27 | 2021-09-29 | Dart NeuroScience, LLC | Substituted furanopyrimidine compounds as pde1 inhibitors |
JP7401442B2 (ja) | 2018-01-31 | 2023-12-19 | イントラ-セルラー・セラピーズ・インコーポレイテッド | 新規使用 |
EP4025202A4 (en) | 2019-09-03 | 2023-08-02 | Intra-Cellular Therapies, Inc. | NOVEL CONNECTIONS |
US12364695B2 (en) | 2020-06-02 | 2025-07-22 | Intra-Cellular Therapies, Inc. | Methods of treating inflammatory disease |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1095906A (en) * | 1977-02-14 | 1981-02-17 | Davis L. Temple, Jr. | Heterocyclopyrimidines, compositions and therapeutic process |
BE863525A (fr) * | 1977-02-14 | 1978-07-31 | Bristol Myers Co | Heterocyclopyrimidines |
ZA902282B (en) * | 1989-03-29 | 1990-12-28 | Merrell Dow Pharma | Selective adenosine receptor compounds |
US5064947A (en) * | 1989-03-29 | 1991-11-12 | Merrell Dow Pharmaceuticals Inc. | Selective adenosine reseptor compounds |
US5173492A (en) * | 1989-09-14 | 1992-12-22 | Kyowa Hakko Kogyo Co., Ltd. | s-Triazolo(3,4-I)purine derivatives |
ATE195739T1 (de) * | 1989-10-20 | 2000-09-15 | Kyowa Hakko Kogyo Kk | Kondensierte purinderivate |
-
1991
- 1991-06-19 IL IL98559A patent/IL98559A0/xx unknown
- 1991-06-19 NZ NZ238609A patent/NZ238609A/en unknown
- 1991-06-19 ZA ZA914727A patent/ZA914727B/xx unknown
- 1991-06-20 CA CA002085733A patent/CA2085733C/en not_active Expired - Fee Related
- 1991-06-20 US US07/949,811 patent/US5393755A/en not_active Expired - Lifetime
- 1991-06-20 TW TW080104761A patent/TW197441B/zh active
- 1991-06-20 KR KR1019920703316A patent/KR960004532B1/ko not_active Expired - Fee Related
- 1991-06-20 WO PCT/US1991/004154 patent/WO1991019717A1/en active IP Right Grant
- 1991-06-20 PL PL91297299A patent/PL169481B1/pl unknown
- 1991-06-20 DE DE69126980T patent/DE69126980T2/de not_active Expired - Fee Related
- 1991-06-20 AU AU81992/91A patent/AU651607B2/en not_active Ceased
- 1991-06-20 RU RU9192016466A patent/RU2080322C1/ru active
- 1991-06-20 AT AT91912779T patent/ATE155786T1/de not_active IP Right Cessation
- 1991-06-20 EP EP91912779A patent/EP0538332B1/en not_active Expired - Lifetime
- 1991-06-20 IE IE212691A patent/IE912126A1/en unknown
- 1991-06-20 JP JP3512084A patent/JPH0747589B2/ja not_active Expired - Fee Related
- 1991-06-20 CZ CS923749A patent/CZ281920B6/cs unknown
- 1991-06-20 HU HU9204032A patent/HUT65623A/hu unknown
-
1992
- 1992-12-17 FI FI925731A patent/FI925731A7/fi not_active Application Discontinuation
- 1992-12-18 NO NO924940A patent/NO924940D0/no unknown
- 1992-12-21 OA OA60319A patent/OA09723A/en unknown
Also Published As
Publication number | Publication date |
---|---|
ZA914727B (en) | 1992-03-25 |
CA2085733C (en) | 1996-03-05 |
TW197441B (cs) | 1993-01-01 |
DE69126980D1 (de) | 1997-09-04 |
HUT65623A (en) | 1994-07-28 |
CZ281920B6 (cs) | 1997-04-16 |
IE912126A1 (en) | 1992-01-01 |
HU9204032D0 (en) | 1993-03-29 |
ATE155786T1 (de) | 1997-08-15 |
AU651607B2 (en) | 1994-07-28 |
WO1991019717A1 (en) | 1991-12-26 |
JPH0747589B2 (ja) | 1995-05-24 |
NO924940L (no) | 1992-12-18 |
RU2080322C1 (ru) | 1997-05-27 |
CZ374992A3 (en) | 1993-10-13 |
AU8199291A (en) | 1992-01-07 |
US5393755A (en) | 1995-02-28 |
NZ238609A (en) | 1993-12-23 |
KR960004532B1 (ko) | 1996-04-06 |
DE69126980T2 (de) | 1998-01-08 |
PL169481B1 (pl) | 1996-07-31 |
FI925731A7 (fi) | 1992-12-17 |
PL297299A1 (cs) | 1992-07-13 |
EP0538332B1 (en) | 1997-07-23 |
IL98559A0 (en) | 1992-07-15 |
NO924940D0 (no) | 1992-12-18 |
JPH05508647A (ja) | 1993-12-02 |
EP0538332A1 (en) | 1993-04-28 |
CA2085733A1 (en) | 1991-12-22 |
OA09723A (en) | 1993-08-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FI925731A0 (fi) | Polycykliska guaninderivat | |
ATE275134T1 (de) | 4-oxo-1,4-dihydro-3-chinolincarboxamide als antivirale mittel | |
ATE155133T1 (de) | Piperazinderivate als 5-ht antagonisten | |
ES2164666T3 (es) | Compuestos plaguicidas de pirimidina. | |
DE69327913D1 (de) | 1,2,4-Oxadiazolyl-Phenoxyalkyl-isoxazole und ihre Anwendung als antivirale Mittel | |
DK0678090T3 (da) | Piperazinderivater | |
DE69431471D1 (de) | Amide derivate als 5-ht1a liganden | |
DE69104475D1 (de) | Harnstoffderivate, ihre herstellung und deren enthaltende arzneimittel. | |
DE69416311D1 (de) | Verwendung von cephem-derivaten als antimetastatische mittel | |
DK0596917T3 (da) | Benzimidazolanthelmintika | |
KR970706280A (ko) | 5-HT1A 길항제로서의 비사이클릭 카복스아미드(Bicyclic carboxamides as 5-HT1 antagonists) | |
ATE203533T1 (de) | INDOLDERIVATE ALS PRODRUGS VON ß5-HT1-LIKEß REZEPTOR AGONISTEN | |
DE69403896D1 (de) | 4-amino-2-(hetero)aryl-butanamide verwenbar als 5-ht1a-antagonisten | |
TR199701289T2 (xx) | Karbapenemlerin esterleri | |
FI961172A0 (fi) | Antineoplastisina aineina käyttökelpoiset 5-(1-fluorivinyyli)-1H-pyrimidiini-2,4-dionijohdannaiset | |
ATE119883T1 (de) | Thioformamidderivate. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application lapsed |