FI921059A - Menetelmä hyötyproteiinien erittämiseksi hiivoista - Google Patents

Menetelmä hyötyproteiinien erittämiseksi hiivoista Download PDF

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Publication number
FI921059A
FI921059A FI921059A FI921059A FI921059A FI 921059 A FI921059 A FI 921059A FI 921059 A FI921059 A FI 921059A FI 921059 A FI921059 A FI 921059A FI 921059 A FI921059 A FI 921059A
Authority
FI
Finland
Prior art keywords
yeasts
secretion
useful proteins
proteins
useful
Prior art date
Application number
FI921059A
Other languages
English (en)
Swedish (sv)
Other versions
FI921059A0 (fi
FI92601C (fi
FI92601B (fi
Inventor
Marja Makarow
Original Assignee
Marja Makarow
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Marja Makarow filed Critical Marja Makarow
Priority to FI921059A priority Critical patent/FI92601C/fi
Publication of FI921059A0 publication Critical patent/FI921059A0/fi
Priority to AU37527/93A priority patent/AU3752793A/en
Priority to US08/295,676 priority patent/US5677172A/en
Priority to EP93906625A priority patent/EP0631627A1/en
Priority to PCT/FI1993/000088 priority patent/WO1993018167A1/en
Publication of FI921059A publication Critical patent/FI921059A/fi
Application granted granted Critical
Publication of FI92601B publication Critical patent/FI92601B/fi
Publication of FI92601C publication Critical patent/FI92601C/fi
Priority to US08/948,591 priority patent/US5939287A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C07K14/395—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
FI921059A 1992-03-11 1992-03-11 Menetelmä hyötyproteiinien erittämiseksi hiivoista FI92601C (fi)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FI921059A FI92601C (fi) 1992-03-11 1992-03-11 Menetelmä hyötyproteiinien erittämiseksi hiivoista
AU37527/93A AU3752793A (en) 1992-03-11 1993-03-11 A method for production of proteins in yeast
US08/295,676 US5677172A (en) 1992-03-11 1993-03-11 Method for production of proteins in yeast
EP93906625A EP0631627A1 (en) 1992-03-11 1993-03-11 A method for production of proteins in yeast
PCT/FI1993/000088 WO1993018167A1 (en) 1992-03-11 1993-03-11 A method for production of proteins in yeast
US08/948,591 US5939287A (en) 1992-03-11 1997-10-10 Method for production of proteins in yeast

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI921059 1992-03-11
FI921059A FI92601C (fi) 1992-03-11 1992-03-11 Menetelmä hyötyproteiinien erittämiseksi hiivoista

Publications (4)

Publication Number Publication Date
FI921059A0 FI921059A0 (fi) 1992-03-11
FI921059A true FI921059A (fi) 1993-09-12
FI92601B FI92601B (fi) 1994-08-31
FI92601C FI92601C (fi) 1994-12-12

Family

ID=8534905

Family Applications (1)

Application Number Title Priority Date Filing Date
FI921059A FI92601C (fi) 1992-03-11 1992-03-11 Menetelmä hyötyproteiinien erittämiseksi hiivoista

Country Status (4)

Country Link
US (2) US5677172A (fi)
EP (1) EP0631627A1 (fi)
FI (1) FI92601C (fi)
WO (1) WO1993018167A1 (fi)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998054339A1 (en) * 1997-05-27 1998-12-03 Hanil Synthetic Fiber Co., Ltd. PROCESS FOR PREPARING RECOMBINANT PROTEINS USING HIGHLY EFFICIENT EXPRESSION VECTOR FROM $i(SACCHAROMYCES CEREVISIAE)
US20030190740A1 (en) 1998-10-13 2003-10-09 The University Of Georgia Research Foundation, Inc Stabilized bioactive peptides and methods of identification, synthesis, and use
WO2000022112A1 (en) * 1998-10-13 2000-04-20 The University Of Georgia Research Foundation, Inc. Stabilized bioactive peptides and methods of identification, synthesis and use
US6875855B1 (en) * 1999-02-26 2005-04-05 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Nucleic acid and amino acid sequences of hemoglobin-response genes in candida albicans and the use of reagents derived from these sequences in the diagnosis of disseminated candida albicans infection
JP2002320485A (ja) * 2000-11-21 2002-11-05 National Institute Of Advanced Industrial & Technology 融合遺伝子発現ベクター及び固定化酵素の製造方法
DE10108211A1 (de) * 2001-02-20 2002-08-22 Aventis Pharma Gmbh Verwendung von Fusionsproteinen, deren N-terminaler Anteil aus einem Hirudinderivat besteht, zur Herstellung rekombinanter Proteine über Sekretion durch Hefen
DE10108100A1 (de) 2001-02-20 2002-08-29 Aventis Pharma Gmbh Verwendung supersekretierbarer Peptide in Verfahren zu deren Herstellung und paralleler Verbesserung der Exportate eines oder mehrerer anderer Polypeptide von Interesse
US7202059B2 (en) * 2001-02-20 2007-04-10 Sanofi-Aventis Deutschland Gmbh Fusion proteins capable of being secreted into a fermentation medium
US7638618B2 (en) * 2001-02-20 2009-12-29 Sanofi-Aventis Deutschland Gmbh Nucleic acids encoding a hirudin and pro-insulin as superscretable peptides and for parallel improvement of the exported forms of one or more polypeptides of interest
CA2638764A1 (en) * 2006-02-28 2007-09-07 Suntory Limited Gene encoding protein responsible for flocculation property of yeast and use thereof
AU2013203326B2 (en) * 2007-06-21 2013-08-01 Technische Universitat Munchen Biological active proteins having increased in vivo and/or in vitro stability
CN101970678B (zh) * 2007-06-21 2014-08-20 慕尼黑科技大学 具有增加的体内和/或体外稳定性的生物学活性蛋白
WO2011053545A1 (en) * 2009-10-30 2011-05-05 Merck Sharp & Dohme Corp. Granulocyte-colony stimulating factor produced in glycoengineered pichia pastoris
CN102883734B (zh) 2010-05-21 2018-01-02 Xl-蛋白有限责任公司 生物合成的脯氨酸/丙氨酸无规卷曲多肽及其用途
RU2502805C1 (ru) * 2012-09-18 2013-12-27 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГУП "ГосНИИгенетика") СПОСОБ МИКРОБИОЛОГИЧЕСКОГО СИНТЕЗА ЦЕЛЕВОГО СЕКРЕТИРУЕМОГО БЕЛКА В ДРОЖЖАХ Saccharomyces cerevisiae

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4914026A (en) * 1983-04-07 1990-04-03 Chiron Corporation Alpha factor leader sequence directed secretion of insulin
US4797359A (en) * 1983-05-10 1989-01-10 Board Of Regents, The University Of Texas System Heat shock regulated production of selected and fused proteins in yeast
RU2091490C1 (ru) * 1985-10-25 1997-09-27 Зимодженетикс, Инк. Способ получения гетерологичного полипептида в эукариотических микроорганизмов
JPH03503410A (ja) * 1988-03-18 1991-08-01 ザ・ジェネラル・ホスピタル・コーポレーション ヒト熱ショック因子
DK105489D0 (da) * 1989-03-03 1989-03-03 Novo Nordisk As Polypeptid
DK300090D0 (da) * 1990-12-19 1990-12-19 Novo Nordisk As Fremgangsmaade til fremstilling af leadersekvenser

Also Published As

Publication number Publication date
WO1993018167A1 (en) 1993-09-16
US5677172A (en) 1997-10-14
EP0631627A1 (en) 1995-01-04
FI921059A0 (fi) 1992-03-11
FI92601C (fi) 1994-12-12
FI92601B (fi) 1994-08-31
US5939287A (en) 1999-08-17

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