FI912635A0 - Expression av hiv-proteiner i drosophila-celler. - Google Patents

Expression av hiv-proteiner i drosophila-celler.

Info

Publication number
FI912635A0
FI912635A0 FI912635A FI912635A FI912635A0 FI 912635 A0 FI912635 A0 FI 912635A0 FI 912635 A FI912635 A FI 912635A FI 912635 A FI912635 A FI 912635A FI 912635 A0 FI912635 A0 FI 912635A0
Authority
FI
Finland
Prior art keywords
proteiner
celler
drosophila
hiv
expression
Prior art date
Application number
FI912635A
Other languages
English (en)
Other versions
FI113475B (fi
Inventor
Hanne Ranch Johansen
Martin Rosenberg
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of FI912635A0 publication Critical patent/FI912635A0/fi
Application granted granted Critical
Publication of FI113475B publication Critical patent/FI113475B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/75—Vector systems having a special element relevant for transcription from invertebrates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FI912635A 1988-12-01 1991-05-31 HIV-proteiinien geeniekspressioyksikkö ja HIV-proteiinien tuottaminen Drosophila-soluissa FI113475B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27838688A 1988-12-01 1988-12-01
PCT/US1989/005155 WO1990006358A1 (en) 1988-12-01 1989-11-29 Expression of hiv proteins in drosophila cells

Publications (2)

Publication Number Publication Date
FI912635A0 true FI912635A0 (fi) 1991-05-31
FI113475B FI113475B (fi) 2004-04-30

Family

ID=23064787

Family Applications (1)

Application Number Title Priority Date Filing Date
FI912635A FI113475B (fi) 1988-12-01 1991-05-31 HIV-proteiinien geeniekspressioyksikkö ja HIV-proteiinien tuottaminen Drosophila-soluissa

Country Status (12)

Country Link
EP (1) EP0446272A4 (fi)
JP (1) JP3085704B2 (fi)
KR (1) KR0152525B1 (fi)
AU (1) AU630649B2 (fi)
CA (1) CA2003794C (fi)
DK (1) DK175461B1 (fi)
FI (1) FI113475B (fi)
IL (1) IL92470A (fi)
NO (1) NO314090B1 (fi)
PT (1) PT92477A (fi)
WO (1) WO1990006358A1 (fi)
ZA (1) ZA899150B (fi)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2739300B1 (en) * 2011-07-05 2019-06-19 Duke University N-terminal deleted gp120 immunogens
CA2850745C (en) 2011-10-03 2022-12-13 Duke University Vaccine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0272858A3 (en) * 1986-12-15 1989-07-12 Repligen Corporation Recombinant hiv envelope proteins produced in insect cells
CA1341345C (en) * 1987-05-08 2002-03-05 Hanne Ranch Johansen Expression of foreign genes in drosophila cells
AP129A (en) * 1988-06-03 1991-04-17 Smithkline Biologicals S A Expression of retrovirus gag protein eukaryotic cells
JPH03504082A (ja) * 1988-12-21 1991-09-12 スミスクライン・バイオロジカルズ 昆虫細胞によるプラスモディウム属サーカムスポロゾイト蛋白の発現

Also Published As

Publication number Publication date
JP3085704B2 (ja) 2000-09-11
EP0446272A4 (en) 1993-01-07
IL92470A (en) 1997-01-10
FI113475B (fi) 2004-04-30
EP0446272A1 (en) 1991-09-18
CA2003794A1 (en) 1990-06-01
KR910700344A (ko) 1991-03-14
DK104991D0 (da) 1991-05-31
JPH04501954A (ja) 1992-04-09
NO912099D0 (no) 1991-05-31
CA2003794C (en) 2000-02-08
IL92470A0 (en) 1990-08-31
AU630649B2 (en) 1992-11-05
KR0152525B1 (ko) 1998-10-01
NO912099L (no) 1991-07-31
PT92477A (pt) 1990-06-29
WO1990006358A1 (en) 1990-06-14
ZA899150B (en) 1991-04-24
NO314090B1 (no) 2003-01-27
DK104991A (da) 1991-05-31
AU4755290A (en) 1990-06-26
DK175461B1 (da) 2004-11-01

Similar Documents

Publication Publication Date Title
FI891434A0 (fi) Framstaellning av vattenhaltiga polymeremulsioner i naervaro av hydrofobt modifierad hydroxietylcellulosa.
FI894430A0 (fi) Uv-haerdbara kompositioner foer tillverkning av loedmaskiner i form av en skyddskupa.
FI890874A0 (fi) Expression av hiv-bindningsproteiner.
FI892088A (fi) Ultraljudsond foer proevning av u-roer i en vaermevaexlare.
FI884573A0 (fi) Foerfarande foer styrning av luftproduktionen i en skruvkompressor.
FI891094A (fi) Foerfarande foer behandling av avfallsvatten i undertryck.
FI890162A (fi) Foerfarande foer inaktivering av foeroekningsdugliga filtrerbara sjukdomsalstrare i blodplasmaprodukter.
FI903659A0 (fi) Foerfarande foer foerbindning av slirskyddskorn i fordondaeck.
FI892951A (fi) Anlaeggning foer styckevis textande av i oeverlappsformation ankommande tryckalster.
FI890233A0 (fi) Foerfarande foer reducering av faellningar i anlaeggningar foer indunstning av sulfitavlut.
FI881812A (fi) Foerfarande foer regenerering av betningssyror i zinkgalvaniseringsprocesser.
FI885491A0 (fi) Anordning foer installering av vatten- och vaermeledningsroer i en byggnad.
FI894264A (fi) Hopsaettning i anordning foer repetering av ljudmeddelande i telefonlinje.
FI912635A0 (fi) Expression av hiv-proteiner i drosophila-celler.
FI885615A (fi) Anordning foer raettande maetningsfel orsakat av aendring av provvolym i vaetskescintillationsraeknare.
FI884263A0 (fi) Anordning foer skaerpning av knivarna i en kapningsvals i en cellulosatorkmaskins arkskaermaskin.
FI890969A0 (fi) Anslutningsdon foer roerformiga staenger i taelt av kupoltyp.
FI880759A0 (fi) Anordning foer neddoppning av foeremaol i vaetska.
FI881199A0 (fi) Expression av proteiner i vaexter.
FI881283A0 (fi) Foerfarande foer datorstyrd utdelning av aiv-foder i en loesdriftsladugaord.
FI884744A (fi) Foerfarande foer bindande av i en kolpulverpanna uppstaoende svavelfoereningar.
FI881551A0 (fi) Lagring av flytgoedsel i traefibermassa.
FI885791A0 (fi) Anordning foer foervaring av klaeder i laost foervaringsrum.
FI883716A0 (fi) Anordning foer foerflyttning i sidled av rullen i en foerflyttningsanordning.
FI881625A0 (fi) Foerfarande foer maetning av enstaka ojaemnheter i vaegen.