FI910756A - Fermentationsfoerfarande foer framstaellning av staurosporin. - Google Patents

Fermentationsfoerfarande foer framstaellning av staurosporin. Download PDF

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Publication number
FI910756A
FI910756A FI910756A FI910756A FI910756A FI 910756 A FI910756 A FI 910756A FI 910756 A FI910756 A FI 910756A FI 910756 A FI910756 A FI 910756A FI 910756 A FI910756 A FI 910756A
Authority
FI
Finland
Prior art keywords
fermentationsfoerfarande
staurosporin
foer framstaellning
framstaellning
foer
Prior art date
Application number
FI910756A
Other languages
English (en)
Other versions
FI910756A0 (fi
Inventor
Daniel R Schroeder
Kin Sing Lam
Jacqueline M Mattei
Grace A Hesler
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of FI910756A0 publication Critical patent/FI910756A0/fi
Publication of FI910756A publication Critical patent/FI910756A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • C12R2001/55—Streptomyces hygroscopicus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces
    • Y10S435/898—Streptomyces hygroscopicus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI910756A 1990-02-20 1991-02-15 Fermentationsfoerfarande foer framstaellning av staurosporin. FI910756A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/482,390 US4973552A (en) 1990-02-20 1990-02-20 Staurosporine fermentation process

Publications (2)

Publication Number Publication Date
FI910756A0 FI910756A0 (fi) 1991-02-15
FI910756A true FI910756A (fi) 1991-08-21

Family

ID=23915871

Family Applications (1)

Application Number Title Priority Date Filing Date
FI910756A FI910756A (fi) 1990-02-20 1991-02-15 Fermentationsfoerfarande foer framstaellning av staurosporin.

Country Status (7)

Country Link
US (1) US4973552A (fi)
EP (1) EP0444503A3 (fi)
JP (1) JPH0737B2 (fi)
CA (1) CA2036669A1 (fi)
FI (1) FI910756A (fi)
HU (1) HUT60526A (fi)
NO (1) NO910649L (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0575955B1 (en) * 1992-06-22 1999-09-15 Kyowa Hakko Kogyo Co., Ltd. Process for producing staurosporine derivatives
US6210935B1 (en) 1995-08-30 2001-04-03 Novartis Ag Staurosporin biosynthesis gene clusters
US6964860B2 (en) * 2001-04-25 2005-11-15 Wyeth Holdings Corporation Glycopeptide antibiotics
EP2068147A1 (en) 2002-09-30 2009-06-10 Auburn University Method of isolation and self-assembly of small protein particles from blood and other biological materials
WO2004094645A1 (en) * 2003-04-22 2004-11-04 Lonza Ag Process for the recovery of staurosporine from a fermentation broth
CN110642872B (zh) * 2019-11-18 2020-12-22 湖北宏中药业股份有限公司 一种星孢菌素提取方法
CN113122591B (zh) * 2019-12-30 2022-11-22 上海医药工业研究院 一种发酵生产星孢菌素的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5373501A (en) * 1976-12-11 1978-06-30 Kitasato Inst Novel antibiotics amm2282 and process for preparing same
US5015578A (en) * 1989-03-23 1991-05-14 Bristol-Myers Squibb Company BMY-41950 antitumor antibiotic

Also Published As

Publication number Publication date
NO910649L (no) 1991-08-21
CA2036669A1 (en) 1991-08-21
EP0444503A3 (en) 1992-02-26
US4973552A (en) 1990-11-27
FI910756A0 (fi) 1991-02-15
NO910649D0 (no) 1991-02-19
HUT60526A (en) 1992-09-28
HU910550D0 (en) 1991-09-30
JPH03244387A (ja) 1991-10-31
JPH0737B2 (ja) 1995-01-11
EP0444503A2 (en) 1991-09-04

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Legal Events

Date Code Title Description
FD Application lapsed