FI905531A0 - Transdermalisk anvaendning av 2-amino-6-n-propylamino-4,5,6,7-tetrahydrobensotiazol. - Google Patents
Transdermalisk anvaendning av 2-amino-6-n-propylamino-4,5,6,7-tetrahydrobensotiazol.Info
- Publication number
- FI905531A0 FI905531A0 FI905531A FI905531A FI905531A0 FI 905531 A0 FI905531 A0 FI 905531A0 FI 905531 A FI905531 A FI 905531A FI 905531 A FI905531 A FI 905531A FI 905531 A0 FI905531 A0 FI 905531A0
- Authority
- FI
- Finland
- Prior art keywords
- propylamino
- amino
- transdermalisk
- tetrahydrobensotiazole
- anvaendning
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3937271A DE3937271A1 (de) | 1989-11-09 | 1989-11-09 | Transdermale applikation von 2-amino-6-n-propylamino-4,5,6,7-tetrahydrobenzothiazol |
Publications (1)
Publication Number | Publication Date |
---|---|
FI905531A0 true FI905531A0 (fi) | 1990-11-08 |
Family
ID=6393163
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI905531A FI905531A0 (fi) | 1989-11-09 | 1990-11-08 | Transdermalisk anvaendning av 2-amino-6-n-propylamino-4,5,6,7-tetrahydrobensotiazol. |
Country Status (17)
Country | Link |
---|---|
US (1) | US5112842A (es) |
EP (1) | EP0428038B1 (es) |
JP (1) | JP3034588B2 (es) |
KR (1) | KR0184867B1 (es) |
AT (1) | ATE108668T1 (es) |
AU (1) | AU635358B2 (es) |
CA (1) | CA2029524C (es) |
CZ (1) | CZ277718B6 (es) |
DE (2) | DE3937271A1 (es) |
DK (1) | DK0428038T3 (es) |
ES (1) | ES2058725T3 (es) |
FI (1) | FI905531A0 (es) |
HU (1) | HU206043B (es) |
IE (1) | IE65564B1 (es) |
IL (1) | IL96276A (es) |
NZ (1) | NZ236002A (es) |
ZA (1) | ZA908953B (es) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3400649A1 (de) * | 1984-01-11 | 1985-07-18 | Jonny 4000 Düsseldorf Janus | Fahrzeugrad |
DE69333009T2 (de) * | 1992-11-09 | 2003-12-04 | Neurogesx, Inc. | Transdermale verabreichung von ketorolac |
US6486310B1 (en) * | 1993-01-28 | 2002-11-26 | Washington University | Gene encoding the rat dopamine D4 receptor |
US6156777A (en) * | 1994-12-15 | 2000-12-05 | Pharmacia & Upjohn Company | Use of pramipexole as a neuroprotective agent |
US5650420A (en) * | 1994-12-15 | 1997-07-22 | Pharmacia & Upjohn Company | Pramipexole as a neuroprotective agent |
DE19701619B4 (de) * | 1997-01-17 | 2007-10-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verwendung von Pramipexol zur Behandlung des restless legs syndroms |
US6001861A (en) | 1998-01-16 | 1999-12-14 | Pharmacia & Upjohn Company | Use of pramipexole in the treatment of restless legs syndrome |
JP2009102351A (ja) * | 1997-07-17 | 2009-05-14 | Nitto Denko Corp | 貼付剤 |
EA004474B1 (ru) * | 1998-05-15 | 2004-04-29 | Фармация Энд Апджон Компани | Комбинированное лечение заболевания цнс, особенно болезни паркинсона, путём совместного введения каберголина и прамипексола |
EP1591119A3 (en) * | 1998-05-15 | 2007-03-28 | Pharmacia & Upjohn Company LLC | Pramipexole for treating CNS diseases, especially Parkinson's disease |
AU760439B2 (en) * | 1998-05-15 | 2003-05-15 | Pharmacia & Upjohn Company | Cabergoline and pramipexole: new uses and combinations |
DE19830201A1 (de) * | 1998-07-07 | 2000-01-13 | Boehringer Ingelheim Pharma | Mittel mit antidepressiver Wirkung |
DE19938825A1 (de) * | 1999-08-19 | 2001-04-26 | Boehringer Ingelheim Pharma | Wirkstoffkombination mit Clonidin |
PE20011074A1 (es) | 2000-02-23 | 2001-10-04 | Upjohn Co | Uso de pramipexol en el tratamiento de trastornos de adiccion |
US8980290B2 (en) | 2000-08-03 | 2015-03-17 | Antares Pharma Ipl Ag | Transdermal compositions for anticholinergic agents |
US20040198706A1 (en) * | 2003-03-11 | 2004-10-07 | Carrara Dario Norberto R. | Methods and formulations for transdermal or transmucosal application of active agents |
US20070225379A1 (en) * | 2001-08-03 | 2007-09-27 | Carrara Dario Norberto R | Transdermal delivery of systemically active central nervous system drugs |
US7198801B2 (en) * | 2000-08-03 | 2007-04-03 | Antares Pharma Ipl Ag | Formulations for transdermal or transmucosal application |
DE60143360D1 (de) * | 2000-08-03 | 2010-12-09 | Antares Pharma Ipl Ag | Zusammensetzung zur transdermalen und/oder transmukosalen Verabreichung von Wirkstoffen, die ausreichende therapeutische Spiegel garantiert |
WO2002069974A1 (en) * | 2001-03-05 | 2002-09-12 | Andrew Holman | Administration of sleep restorative agents |
DE10137162A1 (de) * | 2001-07-30 | 2003-02-20 | Hexal Ag | Matrixkontrolliertes transdermales therapeutisches System zur Anwendung von Pramiprexol und Ropinirol |
DE10138275A1 (de) * | 2001-08-10 | 2003-02-27 | Boehringer Ingelheim Pharma | Verbindungen zur Beseitigung der Anhedonie |
RU2004121177A (ru) * | 2001-12-11 | 2005-03-10 | Юниверсити Оф Вирджиния Пэйтент Фаундейшн (Us) | Применение прамипексола для лечения бокового амитрофического склероза |
US20060281797A1 (en) * | 2001-12-11 | 2006-12-14 | University Of Virginia Patent Foundation | Neurorestoration with R(+) Pramipexole |
DE10333393A1 (de) * | 2003-07-23 | 2005-02-24 | Lts Lohmann Therapie-Systeme Ag | Transdermales Therapeutisches System mit dem Wirkstoff Pramipexol |
MXPA06003316A (es) * | 2003-10-10 | 2006-06-08 | Antares Pharma Ipl Ag | Formulacion farmaceutica transdermica para minimizar los residuos en la piel. |
US8067399B2 (en) * | 2005-05-27 | 2011-11-29 | Antares Pharma Ipl Ag | Method and apparatus for transdermal or transmucosal application of testosterone |
DE602006009670D1 (de) * | 2005-08-15 | 2009-11-19 | Univ Virginia | Neurorestauration mit r(+) pramipexol |
WO2007045620A1 (de) * | 2005-10-18 | 2007-04-26 | Boehringer Ingelheim International Gmbh | Verwendung von pramipexol zur behandlung des moderaten bis schweren restless legs syndroms (rls) |
ITMI20060044A1 (it) * | 2006-01-13 | 2007-07-14 | Dipharma Spa | Sintesi di intermedi pr la preparazione di pramipexolo |
WO2007121188A2 (en) * | 2006-04-10 | 2007-10-25 | Knopp Neurosciences, Inc. | Compositions and methods of using r(+) pramipexole |
US8518926B2 (en) * | 2006-04-10 | 2013-08-27 | Knopp Neurosciences, Inc. | Compositions and methods of using (R)-pramipexole |
CN101426475A (zh) | 2006-04-21 | 2009-05-06 | 安塔雷斯制药Ipl股份公司 | 使用用于经皮或经粘膜应用的制剂治疗热潮红的方法 |
CN101448498B (zh) | 2006-05-16 | 2011-04-27 | 诺普神经科学股份有限公司 | R(+)和s(-)普拉克索的组合物以及使用该组合物的方法 |
WO2008001204A2 (en) * | 2006-06-29 | 2008-01-03 | Antares Pharma Ipl Ag | Transdermal compositions of pramipexole having enhanced permeation properties |
WO2008001200A2 (en) * | 2006-06-29 | 2008-01-03 | Antares Pharma Ipl Ag | Transdermal composition having enhanced color stability |
US20080254118A1 (en) * | 2007-04-11 | 2008-10-16 | Hans-Werner Wernersbach | Process for preparing pramipexole dihydrochloride tablets |
WO2008067991A2 (en) * | 2006-12-08 | 2008-06-12 | Antares Pharma Ipl Ag | Skin-friendly drug complexes for transdermal administration |
US8524695B2 (en) * | 2006-12-14 | 2013-09-03 | Knopp Neurosciences, Inc. | Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same |
US8519148B2 (en) * | 2007-03-14 | 2013-08-27 | Knopp Neurosciences, Inc. | Synthesis of chirally purified substituted benzothiazole diamines |
US20080254117A1 (en) * | 2007-04-10 | 2008-10-16 | Noel Cotton | Process for preparing pramipexole dihydrochloride tablets |
CN102186350A (zh) | 2008-08-19 | 2011-09-14 | 诺普神经科学股份有限公司 | 使用(r)-普拉克索的组合物与方法 |
CA2765876A1 (en) * | 2009-06-19 | 2010-12-23 | Knopp Neurosciences, Inc. | Compositions and methods for treating amyotrophic lateral sclerosis |
KR101307334B1 (ko) * | 2010-07-02 | 2013-09-12 | 주식회사 바이오파마티스 | 프라미펙솔 또는 이의 약학적으로 허용되는 염을 포함하는 안정성이 개선된 서방형 약학 조성물 |
US9512096B2 (en) | 2011-12-22 | 2016-12-06 | Knopp Biosciences, LLP | Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds |
DE102012205493A1 (de) | 2012-04-03 | 2013-10-10 | Acino Ag | Einen Dopamin-Agonisten enthaltendes transdermales Applikationssystem |
US9662313B2 (en) | 2013-02-28 | 2017-05-30 | Knopp Biosciences Llc | Compositions and methods for treating amyotrophic lateral sclerosis in responders |
US9468630B2 (en) | 2013-07-12 | 2016-10-18 | Knopp Biosciences Llc | Compositions and methods for treating conditions related to increased eosinophils |
EP3838271A1 (en) | 2013-07-12 | 2021-06-23 | Knopp Biosciences LLC | Treating elevated levels of eosinophils and/or basophils |
CA2921378A1 (en) | 2013-08-13 | 2015-02-19 | Knopp Biosciences Llc | Compositions and methods for treating plasma cell disorders and b-cell prolymphocytic disorders |
DK3033081T3 (da) | 2013-08-13 | 2021-05-31 | Knopp Biosciences Llc | Sammensætninger og fremgangsmåder til behandling af kronisk urticaria |
JPWO2015129527A1 (ja) * | 2014-02-27 | 2017-03-30 | 株式会社 メドレックス | プラミペキソールを含有する神経変性疾患の治療用貼付剤 |
EP3522843B1 (en) * | 2016-10-07 | 2022-09-21 | Transwell Biotech Co., Ltd. | Pramipexole transdermal delivery system and uses thereof |
EP3558275A1 (en) | 2016-12-20 | 2019-10-30 | LTS Lohmann Therapie-Systeme AG | Transdermal therapeutic system containing asenapine |
RU2764443C2 (ru) | 2016-12-20 | 2022-01-17 | Лтс Ломанн Терапи-Систем Аг | Трансдермальная терапевтическая система, содержащая азенапин и полисилоксан или полиизобутилен |
WO2019002204A1 (en) | 2017-06-26 | 2019-01-03 | Lts Lohmann Therapie-Systeme Ag | TRANSDERMAL THERAPEUTIC SYSTEM CONTAINING ASENAPINE AND SILICONE-TYPE ACRYLIC HYBRID POLYMER |
EP3681474A1 (en) | 2017-09-11 | 2020-07-22 | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. | Compositions and methods for nasal administration of drugs to brain and for systemic effect |
MX2020014286A (es) | 2018-06-20 | 2021-03-25 | Lts Lohmann Therapie Systeme Ag | Sistema terapeutico transdermico que contiene asenapina. |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3572485D1 (en) * | 1984-12-22 | 1989-09-28 | Thomae Gmbh Dr K | Tetrahydro-benzothiazoles, their production and their use as intermediates or drugs |
US4826686A (en) * | 1985-12-14 | 1989-05-02 | Boehringer Ingelheim Kg | Therapeutic system |
US4826860A (en) * | 1987-03-16 | 1989-05-02 | Warner-Lambert Company | Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents |
-
1989
- 1989-11-09 DE DE3937271A patent/DE3937271A1/de not_active Withdrawn
-
1990
- 1990-11-06 EP EP90121170A patent/EP0428038B1/de not_active Expired - Lifetime
- 1990-11-06 ES ES90121170T patent/ES2058725T3/es not_active Expired - Lifetime
- 1990-11-06 DE DE59006506T patent/DE59006506D1/de not_active Expired - Lifetime
- 1990-11-06 DK DK90121170.6T patent/DK0428038T3/da active
- 1990-11-06 KR KR1019900017859A patent/KR0184867B1/ko not_active IP Right Cessation
- 1990-11-06 AT AT90121170T patent/ATE108668T1/de not_active IP Right Cessation
- 1990-11-07 NZ NZ236002A patent/NZ236002A/xx unknown
- 1990-11-08 HU HU907065A patent/HU206043B/hu unknown
- 1990-11-08 ZA ZA908953A patent/ZA908953B/xx unknown
- 1990-11-08 FI FI905531A patent/FI905531A0/fi not_active Application Discontinuation
- 1990-11-08 IL IL9627690A patent/IL96276A/en not_active IP Right Cessation
- 1990-11-08 IE IE402190A patent/IE65564B1/en not_active IP Right Cessation
- 1990-11-08 CA CA002029524A patent/CA2029524C/en not_active Expired - Lifetime
- 1990-11-08 US US07/610,870 patent/US5112842A/en not_active Expired - Lifetime
- 1990-11-08 JP JP2303731A patent/JP3034588B2/ja not_active Expired - Lifetime
- 1990-11-09 AU AU66508/90A patent/AU635358B2/en not_active Expired
- 1990-11-09 CZ CS905534A patent/CZ277718B6/cs not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CZ277718B6 (en) | 1993-03-17 |
JP3034588B2 (ja) | 2000-04-17 |
IE904021A1 (en) | 1991-05-22 |
KR0184867B1 (ko) | 1999-05-01 |
HU206043B (en) | 1992-08-28 |
DE59006506D1 (de) | 1994-08-25 |
IL96276A (en) | 1994-11-28 |
CA2029524A1 (en) | 1991-05-10 |
IE65564B1 (en) | 1995-11-01 |
EP0428038A2 (de) | 1991-05-22 |
ZA908953B (en) | 1992-07-29 |
IL96276A0 (en) | 1991-08-16 |
DK0428038T3 (da) | 1994-08-29 |
CA2029524C (en) | 2002-12-31 |
CS553490A3 (en) | 1992-04-15 |
HUT59005A (en) | 1992-04-28 |
DE3937271A1 (de) | 1991-05-16 |
AU6650890A (en) | 1991-05-16 |
KR910009264A (ko) | 1991-06-28 |
AU635358B2 (en) | 1993-03-18 |
ATE108668T1 (de) | 1994-08-15 |
HU907065D0 (en) | 1991-05-28 |
ES2058725T3 (es) | 1994-11-01 |
NZ236002A (en) | 1993-01-27 |
JPH03170425A (ja) | 1991-07-24 |
US5112842A (en) | 1992-05-12 |
EP0428038A3 (en) | 1991-09-25 |
EP0428038B1 (de) | 1994-07-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application lapsed | ||
FD | Application lapsed |
Owner name: BOEHRINGER INGELHEIM KG |