FI893248A0 - Framstaellning av foereningar med bronkodilatorisk aktivitet. - Google Patents
Framstaellning av foereningar med bronkodilatorisk aktivitet.Info
- Publication number
- FI893248A0 FI893248A0 FI893248A FI893248A FI893248A0 FI 893248 A0 FI893248 A0 FI 893248A0 FI 893248 A FI893248 A FI 893248A FI 893248 A FI893248 A FI 893248A FI 893248 A0 FI893248 A0 FI 893248A0
- Authority
- FI
- Finland
- Prior art keywords
- bronkodilatorisk
- aktivitet
- foereningar
- framstaellning
- med
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/58—Radicals substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
- C07C259/16—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP88306121 | 1988-07-05 |
Publications (2)
Publication Number | Publication Date |
---|---|
FI893248A0 true FI893248A0 (fi) | 1989-07-04 |
FI893248A FI893248A (fi) | 1990-01-06 |
Family
ID=8200128
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI893248A FI893248A (fi) | 1988-07-05 | 1989-07-04 | Framstaellning av foereningar med bronkodilatorisk aktivitet. |
Country Status (14)
Country | Link |
---|---|
US (1) | US5026724A (fi) |
EP (1) | EP0352832B1 (fi) |
JP (1) | JPH0285241A (fi) |
KR (1) | KR900001675A (fi) |
AU (1) | AU619567B2 (fi) |
DE (1) | DE68901424D1 (fi) |
DK (1) | DK332489A (fi) |
ES (1) | ES2051986T3 (fi) |
FI (1) | FI893248A (fi) |
GR (1) | GR3005347T3 (fi) |
IE (1) | IE60969B1 (fi) |
NZ (1) | NZ229773A (fi) |
PT (1) | PT91057B (fi) |
ZA (1) | ZA894880B (fi) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5276052A (en) * | 1990-10-26 | 1994-01-04 | Akzo N.V. | Use of a benzo[b]thiopene-2-carboximidamide derivative |
IE913683A1 (en) * | 1990-10-26 | 1992-05-22 | Akzo Nv | USE OF A BENZO[b]THIOPHENE-2-CARBOXIMIDAMIDE DERIVATIVE |
US5340833A (en) * | 1992-05-01 | 1994-08-23 | Eisai Co., Ltd. | Urokinase inhibitors |
DE4321444A1 (de) * | 1993-06-28 | 1995-01-05 | Bernd Prof Dr Clement | Pharmazeutische Zubereitung |
US5955495A (en) * | 1996-05-03 | 1999-09-21 | Hoffmann-La Roche Inc. | Method of treating diseases of the CNS |
US6291514B1 (en) | 1998-02-09 | 2001-09-18 | 3-Dimensional Pharmaceuticals, Inc. | Heteroaryl amidines, methylamidines and guanidines, preparation thereof, and use thereof as protease inhibitors |
KR101562549B1 (ko) | 2005-05-10 | 2015-10-23 | 인사이트 홀딩스 코포레이션 | 인돌아민 2,3-디옥시게나제의 조절제 및 이의 사용방법 |
TWI382974B (zh) | 2005-12-20 | 2013-01-21 | Incyte Corp | 作為吲哚胺2,3-二氧化酶調節劑之n-羥基甲脒基雜環化物 |
US20080125470A1 (en) | 2006-09-19 | 2008-05-29 | Incyte Corporation | N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase |
CL2007002650A1 (es) | 2006-09-19 | 2008-02-08 | Incyte Corp | Compuestos derivados de heterociclo n-hidroxiamino; composicion farmaceutica, util para tratar cancer, infecciones virales y desordenes neurodegenerativos entre otras. |
PE20110308A1 (es) | 2008-07-08 | 2011-06-10 | Incyte Corp | 1,2,5-oxadiazoles como inhibidores de indolamina 2,3-dioxigenasa |
EP3066085B1 (en) | 2013-11-08 | 2020-05-13 | Incyte Holdings Corporation | Process for the synthesis of an indoleamine 2,3-dioxygenase inhibitor |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1229580A (fi) * | 1967-12-15 | 1971-04-28 | ||
US3910955A (en) * | 1970-12-21 | 1975-10-07 | Aspro Nicholas Ltd | Benzothiophene-ethylamines |
US4158015A (en) * | 1978-08-16 | 1979-06-12 | Mobil Oil Corporation | Process for the stereoselective synthesis of the E isomer of aryl alkyl oximes |
US4737519A (en) * | 1983-12-14 | 1988-04-12 | The Upjohn Company | Substituted naphthalenes, indoles, benzofurans, and benzothiophenes as lipoxygenase inhibitors |
GB8406906D0 (en) * | 1984-03-16 | 1984-04-18 | Akzo Nv | Benzo-thiazole and benzothiophene derivatives |
GB8508588D0 (en) * | 1985-04-02 | 1985-05-09 | Akzo Nv | Indene & napthalene derivatives |
-
1989
- 1989-06-21 ES ES89201621T patent/ES2051986T3/es not_active Expired - Lifetime
- 1989-06-21 DE DE8989201621T patent/DE68901424D1/de not_active Expired - Fee Related
- 1989-06-21 EP EP89201621A patent/EP0352832B1/en not_active Expired - Lifetime
- 1989-06-22 IE IE203889A patent/IE60969B1/en not_active IP Right Cessation
- 1989-06-27 ZA ZA894880A patent/ZA894880B/xx unknown
- 1989-06-29 NZ NZ229773A patent/NZ229773A/en unknown
- 1989-07-04 DK DK332489A patent/DK332489A/da not_active Application Discontinuation
- 1989-07-04 AU AU37837/89A patent/AU619567B2/en not_active Ceased
- 1989-07-04 KR KR1019890009472A patent/KR900001675A/ko not_active Application Discontinuation
- 1989-07-04 FI FI893248A patent/FI893248A/fi not_active Application Discontinuation
- 1989-07-04 PT PT91057A patent/PT91057B/pt active IP Right Grant
- 1989-07-05 JP JP1173892A patent/JPH0285241A/ja active Pending
- 1989-07-05 US US07/375,654 patent/US5026724A/en not_active Expired - Fee Related
-
1992
- 1992-08-05 GR GR920401685T patent/GR3005347T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0352832A1 (en) | 1990-01-31 |
GR3005347T3 (fi) | 1993-05-24 |
DK332489D0 (da) | 1989-07-04 |
US5026724A (en) | 1991-06-25 |
JPH0285241A (ja) | 1990-03-26 |
IE60969B1 (en) | 1994-09-07 |
EP0352832B1 (en) | 1992-05-06 |
IE892038L (en) | 1990-01-05 |
DK332489A (da) | 1990-01-06 |
NZ229773A (en) | 1991-12-23 |
ZA894880B (en) | 1990-03-28 |
KR900001675A (ko) | 1990-02-27 |
DE68901424D1 (de) | 1992-06-11 |
PT91057B (pt) | 1994-12-30 |
PT91057A (pt) | 1990-02-08 |
AU619567B2 (en) | 1992-01-30 |
FI893248A (fi) | 1990-01-06 |
AU3783789A (en) | 1990-01-11 |
ES2051986T3 (es) | 1994-07-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application lapsed | ||
FD | Application lapsed |
Owner name: AKZO N.V. |