FI892016A - Förfarande för framställning av nya, terapeutiskt användbara, eventuellt -substituerade 4-(kinolin-2-ylmetoxi)-fenylättiksyror och -estrar - Google Patents
Förfarande för framställning av nya, terapeutiskt användbara, eventuellt -substituerade 4-(kinolin-2-ylmetoxi)-fenylättiksyror och -estrar Download PDFInfo
- Publication number
- FI892016A FI892016A FI892016A FI892016A FI892016A FI 892016 A FI892016 A FI 892016A FI 892016 A FI892016 A FI 892016A FI 892016 A FI892016 A FI 892016A FI 892016 A FI892016 A FI 892016A
- Authority
- FI
- Finland
- Prior art keywords
- ylmethoxy
- quinolin
- substituted
- esters
- novel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Quinoline Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3814504A DE3814504A1 (de) | 1988-04-29 | 1988-04-29 | (alpha)-substituierte 4-(chinolin-2-yl-methoxy)phenylessigsaeuren und -ester, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
DE3814504 | 1988-04-29 |
Publications (4)
Publication Number | Publication Date |
---|---|
FI892016A0 FI892016A0 (sv) | 1989-04-27 |
FI892016A true FI892016A (sv) | 1989-10-30 |
FI91855B FI91855B (sv) | 1994-05-13 |
FI91855C FI91855C (sv) | 1994-08-25 |
Family
ID=6353182
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI892016A FI91855C (sv) | 1988-04-29 | 1989-04-27 | Förfarande för framställning av nya, terapeutiskt användbara, eventuellt -substituerade 4-(kinolin-2-ylmetoxi)-fenylättiksyror och -estrar |
Country Status (20)
Country | Link |
---|---|
US (1) | US4929626A (sv) |
EP (1) | EP0339416B1 (sv) |
JP (1) | JPH01313466A (sv) |
KR (1) | KR900016136A (sv) |
CN (1) | CN1027068C (sv) |
AT (1) | ATE89819T1 (sv) |
AU (1) | AU614358B2 (sv) |
CA (1) | CA1333803C (sv) |
DD (1) | DD283811A5 (sv) |
DE (2) | DE3814504A1 (sv) |
DK (1) | DK168009B1 (sv) |
ES (1) | ES2054919T3 (sv) |
FI (1) | FI91855C (sv) |
HU (1) | HU205079B (sv) |
IE (1) | IE62888B1 (sv) |
IL (1) | IL90052A (sv) |
NO (1) | NO175149C (sv) |
NZ (1) | NZ228899A (sv) |
PT (1) | PT90382B (sv) |
ZA (1) | ZA893171B (sv) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3632329A1 (de) * | 1986-09-24 | 1988-03-31 | Bayer Ag | Substituierte phenylsulfonamide |
GB8728051D0 (en) * | 1987-12-01 | 1988-01-06 | Leo Pharm Prod Ltd | Chemical compounds |
DE3900261A1 (de) * | 1988-05-31 | 1989-12-07 | Bayer Ag | Substituierte 4-(chinolin-2-yl-methoxy) phenyl-essigsaeure-derivate |
US5232916A (en) * | 1988-06-27 | 1993-08-03 | Merck Frosst Canada, Inc. | Quinoline ether alkanoic acids |
US5102881A (en) * | 1988-06-27 | 1992-04-07 | Merck Frosst Canada, Inc. | Quinoline ether alkanoic acids |
US5194438A (en) * | 1988-07-15 | 1993-03-16 | Basf Aktiengesellschaft | α-arylacrylates substituted by a trifluoromethylpyrimidinyloxy radical, fungicidal compositions and methods |
DE3927931A1 (de) * | 1989-08-24 | 1991-02-28 | Bayer Ag | Disubstituierte (chinolin-2-yl-methoxy)phenylessigsaeure-derivate |
DE3927930A1 (de) * | 1989-08-24 | 1991-02-28 | Bayer Ag | Cyclisch substituierte (chinolin-2-yl-methoxy)phenyl-essig-saeure-derivate |
US5071988A (en) * | 1989-10-27 | 1991-12-10 | American Home Products Corporation | Substituted benzoylbenzene-, biphenyl- and 2-oxazole-alkanoic acid derivatives |
US5021576A (en) * | 1989-10-27 | 1991-06-04 | American Home Products Corporation | 2-Anilino phenylacetic acid derivatives |
US5006547A (en) * | 1990-03-19 | 1991-04-09 | Pfizer Inc. | Tenidap as an inhibitor of the release of elastase by neutrophils |
US5008283A (en) * | 1990-03-19 | 1991-04-16 | Pfizer Inc. | Use of tenidap to inhibit activation of collagenase and to inhibit the activity of myeloperoxidase |
US5204329A (en) * | 1990-06-11 | 1993-04-20 | Du Pont Merck Pharmaceutical Company | Treatment of organ transplantation rejection |
US5254581A (en) * | 1990-06-21 | 1993-10-19 | Imperial Chemical Industries Plc | Pyran derivatives and their use as inhibitors of 5-lipoxygenase |
US4996214A (en) * | 1990-06-28 | 1991-02-26 | Smithkline Beecham Corporation | Quinolinyl substituted phenyl/thioalkanoic acid substituted propionic acids and leucotriene antagonist use thereof |
US5187180A (en) * | 1990-07-26 | 1993-02-16 | Merck Frosst Canada, Inc. | (quinolin-2-ylmethoxy)heterotetrahydrocarbazoles as inhibitors of the biosynthesis of leukotrienes |
US5221678A (en) * | 1990-07-26 | 1993-06-22 | Merck Frosst Canada, Inc. | (quinolin-2-ylmethoxy)tetrahydrocarbazoles as inhibitors of the biosynthesis of leukotrienes |
US5266568A (en) * | 1990-10-12 | 1993-11-30 | Merck Frosst Canada, Inc. | Hydroxyalkylquinoline ether acids as leukotriene antagonists |
US5856322A (en) * | 1990-10-12 | 1999-01-05 | Merck Frosst Canada, Inc. | Unsaturated hydroxyalkylquinoline acids as leukotriene antagonists |
DE4226649A1 (de) * | 1992-08-12 | 1994-02-17 | Bayer Ag | Neue isobutylsubstituierte Methansulfonyl-chinolylmethoxyphenyl-cycloalkylessigsäureaminole |
DE4105551A1 (de) * | 1991-02-22 | 1992-08-27 | Bayer Ag | 2-substituierte chinoline, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln |
DE4139751A1 (de) * | 1991-12-03 | 1993-06-09 | Bayer Ag, 5090 Leverkusen, De | Thiazolyl substituierte chinolylmethoxyphenylessigsaeurederivate |
US5304563A (en) * | 1991-02-22 | 1994-04-19 | Bayer Aktiengesellschaft | 2-substituted quinolines, and their use in medicaments |
DE4112533A1 (de) * | 1991-04-17 | 1992-10-22 | Bayer Ag | Verfahren zur herstellung von enantiomerenreinen substituierten (chinolin-2-yl-methoxy)phenyl-essigsaeuren |
EP0540165A1 (en) * | 1991-10-03 | 1993-05-05 | Zeneca Limited | Alkanoic acid derivatives |
DE4139750A1 (de) * | 1991-12-03 | 1993-06-09 | Bayer Ag, 5090 Leverkusen, De | Chinolylmethoxyphenylessigsaeure-acylamide und -harnstoffe |
US5270324A (en) * | 1992-04-10 | 1993-12-14 | Merck Frosst Canada, Inc. | Fluorinated hydroxyalkylquinoline acids as leukotriene antagonists |
DE4219765A1 (de) * | 1992-06-17 | 1993-12-23 | Bayer Ag | Substituierte (Benzothiazolyl- und Chinoxalyl-methoxy)phenylessigsäurederivate |
DE4226519A1 (de) * | 1992-08-11 | 1994-02-17 | Bayer Ag | 3-Substituierte Chinolylmethoxy-phenylessigsäurederivate |
ES2061406B1 (es) * | 1993-05-07 | 1995-06-01 | Uriach & Cia Sa J | Nuevos derivados de la 2-(quinolina) con actividad farmacologica. |
DE4443891A1 (de) * | 1994-12-09 | 1996-06-13 | Bayer Ag | Heterocyclisch substituierte Oxy-phenyl-(phenyl)glycinolamide |
DE4443892A1 (de) * | 1994-12-09 | 1996-06-13 | Bayer Ag | 4-(Chinolin-2-yl-methoxy)-phenyl-essigsäurederivate |
WO2008067566A1 (en) | 2006-11-30 | 2008-06-05 | Amira Pharmaceuticals, Inc. | Compositions and treatments comprising 5-lipoxygenase-activating protein inhibitors and nitric oxide modulators |
US10080748B2 (en) | 2014-02-04 | 2018-09-25 | Bioscience Pharma Partners, Llc | Use of flap inhibitors to reduce neuroinflammation mediated injury in the central nervous system |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE56702B1 (en) * | 1982-12-01 | 1991-11-06 | Usv Pharma Corp | Antiinflammatory antiallergic compounds |
ZA858347B (en) * | 1984-10-30 | 1986-09-24 | Usv Pharma Corp | Anti-inflammatory/anti-allergic compounds |
NO174506B (no) * | 1984-10-30 | 1994-02-07 | Usv Pharma Corp | Analogifremgangsmaate ved fremstilling av terapeutisk aktive forbindelser |
US4642347A (en) * | 1985-05-21 | 1987-02-10 | American Home Products Corporation | 3(2-quinolinylalkoxy)phenols |
US4661499A (en) * | 1985-06-18 | 1987-04-28 | Merck Frosst Canada, Inc. | 2-[(substituted)-phenoxymethyl]quinolines |
-
1988
- 1988-04-29 DE DE3814504A patent/DE3814504A1/de not_active Withdrawn
-
1989
- 1989-04-12 US US07/336,974 patent/US4929626A/en not_active Expired - Fee Related
- 1989-04-13 NO NO891523A patent/NO175149C/no unknown
- 1989-04-17 ES ES89106816T patent/ES2054919T3/es not_active Expired - Lifetime
- 1989-04-17 AT AT89106816T patent/ATE89819T1/de not_active IP Right Cessation
- 1989-04-17 DE DE8989106816T patent/DE58904459D1/de not_active Expired - Fee Related
- 1989-04-17 EP EP89106816A patent/EP0339416B1/de not_active Expired - Lifetime
- 1989-04-24 IL IL90052A patent/IL90052A/xx not_active IP Right Cessation
- 1989-04-25 JP JP1103592A patent/JPH01313466A/ja active Pending
- 1989-04-26 NZ NZ228899A patent/NZ228899A/en unknown
- 1989-04-27 FI FI892016A patent/FI91855C/sv not_active IP Right Cessation
- 1989-04-27 DD DD89328033A patent/DD283811A5/de not_active IP Right Cessation
- 1989-04-27 CA CA000597990A patent/CA1333803C/en not_active Expired - Fee Related
- 1989-04-27 PT PT90382A patent/PT90382B/pt not_active IP Right Cessation
- 1989-04-28 AU AU33852/89A patent/AU614358B2/en not_active Ceased
- 1989-04-28 KR KR1019890005637A patent/KR900016136A/ko not_active Application Discontinuation
- 1989-04-28 HU HU892044A patent/HU205079B/hu not_active IP Right Cessation
- 1989-04-28 DK DK208789A patent/DK168009B1/da not_active IP Right Cessation
- 1989-04-28 ZA ZA893171A patent/ZA893171B/xx unknown
- 1989-04-28 IE IE140289A patent/IE62888B1/en not_active IP Right Cessation
- 1989-04-29 CN CN89102886A patent/CN1027068C/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN1045777A (zh) | 1990-10-03 |
JPH01313466A (ja) | 1989-12-18 |
ES2054919T3 (es) | 1994-08-16 |
DK168009B1 (da) | 1994-01-17 |
DK208789D0 (da) | 1989-04-28 |
CN1027068C (zh) | 1994-12-21 |
IE62888B1 (en) | 1995-03-08 |
NZ228899A (en) | 1991-06-25 |
KR900016136A (ko) | 1990-11-12 |
CA1333803C (en) | 1995-01-03 |
HU205079B (en) | 1992-03-30 |
AU614358B2 (en) | 1991-08-29 |
HUT50779A (en) | 1990-03-28 |
EP0339416A1 (de) | 1989-11-02 |
IL90052A (en) | 1993-07-08 |
ATE89819T1 (de) | 1993-06-15 |
AU3385289A (en) | 1989-11-02 |
PT90382B (pt) | 1994-09-30 |
DK208789A (da) | 1989-10-30 |
IL90052A0 (en) | 1989-12-15 |
FI892016A0 (sv) | 1989-04-27 |
PT90382A (pt) | 1989-11-10 |
DE3814504A1 (de) | 1989-11-09 |
NO175149B (no) | 1994-05-30 |
IE891402L (en) | 1989-10-29 |
NO891523D0 (no) | 1989-04-13 |
DD283811A5 (de) | 1990-10-24 |
FI91855B (sv) | 1994-05-13 |
ZA893171B (en) | 1989-12-27 |
NO891523L (no) | 1989-10-30 |
DE58904459D1 (de) | 1993-07-01 |
EP0339416B1 (de) | 1993-05-26 |
FI91855C (sv) | 1994-08-25 |
NO175149C (no) | 1994-09-07 |
US4929626A (en) | 1990-05-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FI892016A (sv) | Förfarande för framställning av nya, terapeutiskt användbara, eventuellt -substituerade 4-(kinolin-2-ylmetoxi)-fenylättiksyror och -estrar | |
FI892603A0 (sv) | Förfarande för framställning av nya, terapeutiskt användbara 4-(kinolin-2-ylmetoxi)fenylättiksyraderivat | |
SE8101064L (sv) | Topiska farmaceutiska preparat innehallande salter av alkankarbonsyror samt nya karbonsyrasalter och forfarande for framstellning derav | |
DE3888642D1 (de) | Rollflasche zur Züchtung von Zellengewebekulturen. | |
NO862734D0 (no) | Fremgangsmaate for fremstilling av hyaluronsyreestere. | |
AU6805781A (en) | Oral absorption of polar bioactive agents | |
NO864425D0 (no) | Fremgangsmaate for fremstilling av terapeutisk aktive heterocyklyloksoftalazinyl-eddiksyre-derivater. | |
AU5586790A (en) | Substituted (quinolin-2-yl-methoxy)phenyl-acyl-sulphonamides and-cyanamides, processes for their preparation and their use in medicaments | |
ES2054177T3 (es) | Derivados disubstituidos del acido (quinolin-2-il-metoxi)fenilacetico. | |
DE59007437D1 (de) | Cyclisch substituierte (Chinolin-2-yl-methoxy)phenyl-essigsäure-Derivate. | |
DE68901105D1 (de) | Alkensaeurederivate. | |
FI860816A0 (sv) | Förfarande för framställning av terapeutiskt användbara polyprenylföreningar | |
NO159767C (no) | Anvendelse av et hjelpestoff som tilsetning til beta-laktamantibiotikum for aa oeke absorpsjonsgraden av antibiotikumet i blodet ved oral administrering. | |
AU5643686A (en) | Novel carboxylic acid esters, methods for production thereof and insecticides containing them as the active ingredient | |
ATA188385A (de) | Verwendung von peroxydiphosphaten zur herstellung von pharmazeutischen tabletten bzw. pharmazeutischen waesserigen loesungen | |
DE3877747D1 (de) | Glasartige matrize zur verabreichung von heilmitteln. | |
NO863005D0 (no) | Fremgangsmaate for fremstilling av terapeutisk aktive 1,4,5,6,7,8-heksahydro-2-alkyl-4-aryl-5-okso-1,7-naftyridin-3-karboksylsyreesterderivater. | |
ES528023A0 (es) | Procedimiento de preparacion de nuevos esteres del acido vinilciclopropancarboxilico en su forma racemica u opticamente activa, con actividad pesticida. | |
ATE53384T1 (de) | 3-mercapto-2-oxo-1-pyrrolidinessigsaeurederivate verfahren zur herstellung und pharmazeutische zusammensetzungen die sie enthalten. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB | Publication of examined application | ||
MM | Patent lapsed | ||
MM | Patent lapsed |
Owner name: BAYER AKTIENGESELLSCHAFT |