FI891840A - Foerfarande foer framstaellning av 5-/2-/n- (2-amino-2-oxoetyl) metyl-amino/etyl/-3-hydroxi-2- (4-metoxifenyl) -2,3-dihydro-5h-1,5-bensodiazepin-4-onderivat. - Google Patents

Foerfarande foer framstaellning av 5-/2-/n- (2-amino-2-oxoetyl) metyl-amino/etyl/-3-hydroxi-2- (4-metoxifenyl) -2,3-dihydro-5h-1,5-bensodiazepin-4-onderivat. Download PDF

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Publication number
FI891840A
FI891840A FI891840A FI891840A FI891840A FI 891840 A FI891840 A FI 891840A FI 891840 A FI891840 A FI 891840A FI 891840 A FI891840 A FI 891840A FI 891840 A FI891840 A FI 891840A
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FI
Finland
Prior art keywords
amino
onderivat
bensodiazepin
methoxifenyl
eecl
Prior art date
Application number
FI891840A
Other languages
English (en)
Finnish (fi)
Other versions
FI891840A0 (fi
Inventor
Alistair Lochead
Jean-Claude Muller
Colombe Denys
Andre Dumas
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of FI891840A0 publication Critical patent/FI891840A0/fi
Publication of FI891840A publication Critical patent/FI891840A/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI891840A 1988-04-19 1989-04-18 Foerfarande foer framstaellning av 5-/2-/n- (2-amino-2-oxoetyl) metyl-amino/etyl/-3-hydroxi-2- (4-metoxifenyl) -2,3-dihydro-5h-1,5-bensodiazepin-4-onderivat. FI891840A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8805131A FR2630109B1 (fr) 1988-04-19 1988-04-19 Derives de ((n-(amino-2 oxo-2 ethyl)methylamino)-2 ethyl)-5 hydroxy-3 (methoxy-4 phenyl)-2 dihydro-2,3 5h-benzothiazepine-1,5 one-4, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
FI891840A0 FI891840A0 (fi) 1989-04-18
FI891840A true FI891840A (fi) 1989-10-20

Family

ID=9365423

Family Applications (1)

Application Number Title Priority Date Filing Date
FI891840A FI891840A (fi) 1988-04-19 1989-04-18 Foerfarande foer framstaellning av 5-/2-/n- (2-amino-2-oxoetyl) metyl-amino/etyl/-3-hydroxi-2- (4-metoxifenyl) -2,3-dihydro-5h-1,5-bensodiazepin-4-onderivat.

Country Status (14)

Country Link
US (1) US4914092A (no)
EP (1) EP0338892A1 (no)
JP (1) JPH01311073A (no)
KR (1) KR890016028A (no)
AU (1) AU616003B2 (no)
DK (1) DK185589A (no)
FI (1) FI891840A (no)
FR (1) FR2630109B1 (no)
HU (1) HU201320B (no)
IL (1) IL90000A0 (no)
NO (1) NO891574L (no)
NZ (1) NZ228789A (no)
PT (1) PT90300A (no)
ZA (1) ZA892841B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2624117B1 (fr) * 1987-12-08 1991-02-22 Synthelabo Derives de hydroxy-3 (methoxy-4 phenyl)-2 (methylamino-2 ethyl)-5 dihydro-2,3 5h-benzothiazepine-1,5 one-4, leur preparation et leur application en therapeutique
FR2653122B1 (fr) * 1989-10-17 1994-04-15 Synthelabo Derives de 5-[2-[[2-amino-2-oxoethyl]methylamino]ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5(5h)-benzothiazepine-4-one, leur preparation et leur application en therapeutique.
FR2670785B1 (fr) * 1990-12-20 1993-07-09 Synthelabo Derives de (methoxy-4 phenyl)-2 (methylamino-2 ethyl)-5 dihydro-2,3 5h-benzothiazepine-1,5 one-4, leur preparation et leur application en therapeutique.
EP0702009B1 (en) * 1994-09-16 1998-07-01 Orion Corporation Fermion Method for the preparation of pharmaceutically active benzothiazepine derivatives
EP1175209A2 (en) * 1999-04-30 2002-01-30 Merab Lomia Use of antiepileptics for treating respiratory disorders, in particular asthmatic disorders
EP1196386A2 (en) 1999-07-06 2002-04-17 Vertex Pharmaceuticals Incorporated N-substituted glycine derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH538492A (de) * 1970-10-07 1973-06-30 Hoffmann La Roche Verfahren zur Herstellung von Benzodiazepin-Derivaten
FR2597097B1 (fr) * 1986-04-15 1988-12-02 Synthelabo Derives de benzothiazepine-1, 5, leur preparation et leur application en therapeutique
DE3771143D1 (de) * 1986-08-20 1991-08-08 Mcneilab Inc Benzothiazepin-vasodilatoren mit aralkylsubstitution.
US4729994A (en) * 1986-08-20 1988-03-08 Mcneilab, Inc. Benzothiazepine vasodilators having aralkyl substitution
FR2624117B1 (fr) * 1987-12-08 1991-02-22 Synthelabo Derives de hydroxy-3 (methoxy-4 phenyl)-2 (methylamino-2 ethyl)-5 dihydro-2,3 5h-benzothiazepine-1,5 one-4, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
HU201320B (en) 1990-10-28
NZ228789A (en) 1990-07-26
US4914092A (en) 1990-04-03
NO891574D0 (no) 1989-04-18
AU616003B2 (en) 1991-10-17
PT90300A (pt) 1989-11-10
JPH01311073A (ja) 1989-12-15
AU3315289A (en) 1989-10-26
FI891840A0 (fi) 1989-04-18
FR2630109A1 (fr) 1989-10-20
KR890016028A (ko) 1989-11-28
EP0338892A1 (fr) 1989-10-25
NO891574L (no) 1989-10-20
IL90000A0 (en) 1989-12-15
FR2630109B1 (fr) 1991-11-29
ZA892841B (en) 1989-12-27
DK185589D0 (da) 1989-04-18
HUT51608A (en) 1990-05-28
DK185589A (da) 1989-10-20

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