IL90000A0 - Benzothiazepin-4-one derivatives,their preparation and their application in therapy - Google Patents

Benzothiazepin-4-one derivatives,their preparation and their application in therapy

Info

Publication number
IL90000A0
IL90000A0 IL90000A IL9000089A IL90000A0 IL 90000 A0 IL90000 A0 IL 90000A0 IL 90000 A IL90000 A IL 90000A IL 9000089 A IL9000089 A IL 9000089A IL 90000 A0 IL90000 A0 IL 90000A0
Authority
IL
Israel
Prior art keywords
benzothiazepin
therapy
derivatives
preparation
application
Prior art date
Application number
IL90000A
Other languages
English (en)
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of IL90000A0 publication Critical patent/IL90000A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D281/00Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02Seven-membered rings
    • C07D281/04Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
IL90000A 1988-04-19 1989-04-18 Benzothiazepin-4-one derivatives,their preparation and their application in therapy IL90000A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8805131A FR2630109B1 (fr) 1988-04-19 1988-04-19 Derives de ((n-(amino-2 oxo-2 ethyl)methylamino)-2 ethyl)-5 hydroxy-3 (methoxy-4 phenyl)-2 dihydro-2,3 5h-benzothiazepine-1,5 one-4, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
IL90000A0 true IL90000A0 (en) 1989-12-15

Family

ID=9365423

Family Applications (1)

Application Number Title Priority Date Filing Date
IL90000A IL90000A0 (en) 1988-04-19 1989-04-18 Benzothiazepin-4-one derivatives,their preparation and their application in therapy

Country Status (14)

Country Link
US (1) US4914092A (xx)
EP (1) EP0338892A1 (xx)
JP (1) JPH01311073A (xx)
KR (1) KR890016028A (xx)
AU (1) AU616003B2 (xx)
DK (1) DK185589A (xx)
FI (1) FI891840A (xx)
FR (1) FR2630109B1 (xx)
HU (1) HU201320B (xx)
IL (1) IL90000A0 (xx)
NO (1) NO891574L (xx)
NZ (1) NZ228789A (xx)
PT (1) PT90300A (xx)
ZA (1) ZA892841B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2624117B1 (fr) * 1987-12-08 1991-02-22 Synthelabo Derives de hydroxy-3 (methoxy-4 phenyl)-2 (methylamino-2 ethyl)-5 dihydro-2,3 5h-benzothiazepine-1,5 one-4, leur preparation et leur application en therapeutique
FR2653122B1 (fr) * 1989-10-17 1994-04-15 Synthelabo Derives de 5-[2-[[2-amino-2-oxoethyl]methylamino]ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5(5h)-benzothiazepine-4-one, leur preparation et leur application en therapeutique.
FR2670785B1 (fr) * 1990-12-20 1993-07-09 Synthelabo Derives de (methoxy-4 phenyl)-2 (methylamino-2 ethyl)-5 dihydro-2,3 5h-benzothiazepine-1,5 one-4, leur preparation et leur application en therapeutique.
ES2118292T3 (es) * 1994-09-16 1998-09-16 Orion Corp Fermion Metodo para la preparacion de 3-hidroxi-5-(2-dimetilamino)-etil)-2,3-dihidro-4-(metoxifenil)-1,5-benzotiazepin-4(5h)-ona y uso del producto para elaborar compuestos farmaceuticamente activos.
WO2000066096A2 (en) * 1999-04-30 2000-11-09 Merab Lomia Use of antiepileptics for treating respiratory disorders, in particular asthmatic disorders
JP2003503479A (ja) 1999-07-06 2003-01-28 バーテックス ファーマシューティカルズ インコーポレイテッド N置換化グリシン誘導体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH538492A (de) * 1970-10-07 1973-06-30 Hoffmann La Roche Verfahren zur Herstellung von Benzodiazepin-Derivaten
FR2597097B1 (fr) * 1986-04-15 1988-12-02 Synthelabo Derives de benzothiazepine-1, 5, leur preparation et leur application en therapeutique
US4729994A (en) * 1986-08-20 1988-03-08 Mcneilab, Inc. Benzothiazepine vasodilators having aralkyl substitution
ATE64925T1 (de) * 1986-08-20 1991-07-15 Mcneilab Inc Benzothiazepin-vasodilatoren mit aralkylsubstitution.
FR2624117B1 (fr) * 1987-12-08 1991-02-22 Synthelabo Derives de hydroxy-3 (methoxy-4 phenyl)-2 (methylamino-2 ethyl)-5 dihydro-2,3 5h-benzothiazepine-1,5 one-4, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
NZ228789A (en) 1990-07-26
EP0338892A1 (fr) 1989-10-25
DK185589A (da) 1989-10-20
HU201320B (en) 1990-10-28
FI891840A (fi) 1989-10-20
PT90300A (pt) 1989-11-10
HUT51608A (en) 1990-05-28
AU616003B2 (en) 1991-10-17
FI891840A0 (fi) 1989-04-18
FR2630109A1 (fr) 1989-10-20
FR2630109B1 (fr) 1991-11-29
AU3315289A (en) 1989-10-26
KR890016028A (ko) 1989-11-28
US4914092A (en) 1990-04-03
ZA892841B (en) 1989-12-27
NO891574D0 (no) 1989-04-18
NO891574L (no) 1989-10-20
JPH01311073A (ja) 1989-12-15
DK185589D0 (da) 1989-04-18

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