FI883285A7 - 2-amino-5 -hydroxi-4-pyrimidoner. - Google Patents

2-amino-5 -hydroxi-4-pyrimidoner. Download PDF

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Publication number
FI883285A7
FI883285A7 FI883285A FI883285A FI883285A7 FI 883285 A7 FI883285 A7 FI 883285A7 FI 883285 A FI883285 A FI 883285A FI 883285 A FI883285 A FI 883285A FI 883285 A7 FI883285 A7 FI 883285A7
Authority
FI
Finland
Prior art keywords
hydroxi
pyrimidone
amino
Prior art date
Application number
FI883285A
Other languages
English (en)
Finnish (fi)
Other versions
FI883285A0 (fi
Inventor
Frederick Judson Walker
John Lawrence Lamattina
Brian Thomas O'neill
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI883285A0 publication Critical patent/FI883285A0/fi
Publication of FI883285A7 publication Critical patent/FI883285A7/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Hydrogenated Pyridines (AREA)
FI883285A 1987-07-09 1988-07-08 2-amino-5 -hydroxi-4-pyrimidoner. FI883285A7 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1987/001608 WO1989000423A1 (en) 1987-07-09 1987-07-09 2-amino-5-hydroxy-4-pyrimidones

Publications (2)

Publication Number Publication Date
FI883285A0 FI883285A0 (fi) 1988-07-08
FI883285A7 true FI883285A7 (fi) 1989-01-10

Family

ID=22202454

Family Applications (1)

Application Number Title Priority Date Filing Date
FI883285A FI883285A7 (fi) 1987-07-09 1988-07-08 2-amino-5 -hydroxi-4-pyrimidoner.

Country Status (12)

Country Link
EP (1) EP0303348B1 (Direct)
JP (1) JPH0629264B2 (Direct)
AT (1) ATE71370T1 (Direct)
CA (1) CA1310642C (Direct)
DE (1) DE3867563D1 (Direct)
DK (1) DK381188A (Direct)
ES (1) ES2037833T3 (Direct)
FI (1) FI883285A7 (Direct)
GR (1) GR3003908T3 (Direct)
IE (1) IE60210B1 (Direct)
PT (1) PT87944B (Direct)
WO (1) WO1989000423A1 (Direct)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201111705D0 (en) * 2011-07-07 2011-08-24 Takeda Pharmaceutical Compounds and their use
JO3115B1 (ar) 2011-08-22 2017-09-20 Takeda Pharmaceuticals Co مركبات بيريدازينون واستخدامها كمثبطات daao
US9221809B2 (en) 2011-10-31 2015-12-29 Merck Sharp & Dohme Corp. Aminopyrimidinones as interleukin receptor-associated kinase inhibitors
AP2014007637A0 (en) 2011-11-15 2014-05-31 Takeda Pharmaceutical Dihydroxy aromatic heterocyclic compound
GB201222711D0 (en) 2012-12-17 2013-01-30 Takeda Pharmaceutical Novel compounds
WO2020163689A1 (en) 2019-02-08 2020-08-13 University Of Pittsburgh - Of The Commonwealth System Of Higher Education 20-hete formation inhibitors

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB756189A (en) 1954-02-01 1956-08-29 Ici Ltd New pyrimidine derivatives
US4153793A (en) * 1973-05-03 1979-05-08 Smith Kline & French Laboratories Limited Imidazo alkylamino pyrimidones
IN153791B (Direct) * 1979-03-10 1984-08-18 Soc D Etudes Prod Chimique
FR2503162A1 (fr) 1981-04-07 1982-10-08 Pharmindustrie Nouveaux derives de piperazino-2 pyrimidine, procedes pour leur preparation et leur utilisation comme medicaments ou comme intermediaires pour la fabrication de medicaments
US4554276A (en) * 1983-10-03 1985-11-19 Pfizer Inc. 2-Amino-5-hydroxy-4-methylpyrimidine derivatives
GB8421427D0 (en) 1984-08-23 1984-09-26 Smith Kline French Lab Chemical compounds
DE3436380A1 (de) * 1984-10-04 1986-04-10 Bayer Ag, 5090 Leverkusen Selektiv-fungizide mittel auf pyrimidin-derivat-basis
JPS61205260A (ja) * 1985-03-08 1986-09-11 Zeria Shinyaku Kogyo Kk 新規な２−置換アミノ−６−（２−メトキシフエニ−ル）−４（３ｈ）−ピリミドン誘導体及びその製造法

Also Published As

Publication number Publication date
PT87944B (pt) 1995-03-01
CA1310642C (en) 1992-11-24
JPH0629264B2 (ja) 1994-04-20
IE60210B1 (en) 1994-06-15
GR3003908T3 (Direct) 1993-03-16
ATE71370T1 (de) 1992-01-15
EP0303348B1 (en) 1992-01-08
JPS6429367A (en) 1989-01-31
DK381188D0 (da) 1988-07-08
DK381188A (da) 1989-02-21
IE882107L (en) 1989-01-09
DE3867563D1 (en) 1992-02-20
WO1989000423A1 (en) 1989-01-26
ES2037833T3 (es) 1993-07-01
FI883285A0 (fi) 1988-07-08
EP0303348A1 (en) 1989-02-15
PT87944A (pt) 1989-06-30

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Legal Events

Date Code Title Description
FD Application lapsed
MM Patent lapsed

Owner name: PFIZER INC.