FI882688A7 - Foerfarande foer framstaellning av antiinflammatoriska furanonfoereningar. - Google Patents
Foerfarande foer framstaellning av antiinflammatoriska furanonfoereningar. Download PDFInfo
- Publication number
- FI882688A7 FI882688A7 FI882688A FI882688A FI882688A7 FI 882688 A7 FI882688 A7 FI 882688A7 FI 882688 A FI882688 A FI 882688A FI 882688 A FI882688 A FI 882688A FI 882688 A7 FI882688 A7 FI 882688A7
- Authority
- FI
- Finland
- Prior art keywords
- furanonfoereningar
- antiinflammatoriska
- foerfarande foer
- foer framstaellning
- framstaellning
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/60—Two oxygen atoms, e.g. succinic anhydride
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
- C07F7/0814—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring said ring is substituted at a C ring atom by Si
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Furan Compounds (AREA)
- Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
- Measurement Of Velocity Or Position Using Acoustic Or Ultrasonic Waves (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5928287A | 1987-06-08 | 1987-06-08 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI882688A0 FI882688A0 (fi) | 1988-06-07 |
| FI882688A7 true FI882688A7 (fi) | 1988-12-09 |
Family
ID=22021988
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI882688A FI882688A7 (fi) | 1987-06-08 | 1988-06-07 | Foerfarande foer framstaellning av antiinflammatoriska furanonfoereningar. |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0295056B1 (enExample) |
| JP (1) | JPS6413078A (enExample) |
| KR (1) | KR890000454A (enExample) |
| CN (1) | CN1031839A (enExample) |
| AT (1) | ATE79115T1 (enExample) |
| AU (1) | AU609139B2 (enExample) |
| CA (1) | CA1329390C (enExample) |
| DE (1) | DE3873428T2 (enExample) |
| DK (1) | DK311288A (enExample) |
| EG (1) | EG18472A (enExample) |
| ES (1) | ES2042742T3 (enExample) |
| FI (1) | FI882688A7 (enExample) |
| GR (1) | GR3005957T3 (enExample) |
| HU (1) | HU204519B (enExample) |
| IL (1) | IL86633A (enExample) |
| MY (1) | MY103301A (enExample) |
| NO (1) | NO173012C (enExample) |
| NZ (1) | NZ224708A (enExample) |
| PT (1) | PT87683B (enExample) |
| ZA (1) | ZA883758B (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5043457A (en) * | 1990-04-17 | 1991-08-27 | Allergan, Inc. | 2(5H)-furanones substituted in the 3 position, as Ca2+ channel antagonists and anti-inflammatory agents |
| US5134128A (en) * | 1987-06-08 | 1992-07-28 | Allergan, Inc. | Anti-inflammatory furanones |
| US5037811A (en) * | 1990-04-17 | 1991-08-06 | Allergan, Inc. | 4-(oxygen, sulfur or nitrogen substituted)-methyl 5-hydroxy-2(5H)-furanones as anti-inflammatory agents |
| US5059611A (en) * | 1988-11-18 | 1991-10-22 | Allergan, Inc. | Anti-inflammatory 5-hydroxy-2-furanones |
| US5171863A (en) * | 1987-06-08 | 1992-12-15 | Allergan, Inc. | Intermediates for preparing 4-substituted 2-5(H)-furanones as anti-inflammatory agents |
| US5089485A (en) * | 1988-11-18 | 1992-02-18 | Allergan, Inc. | Anti-inflammatory furanones |
| US5081147A (en) * | 1990-03-15 | 1992-01-14 | Allergan, Inc. | 4-(1-hydroxy-2-substituted amino)ethyl-5-hydroxy-2(5H)-furanones as anti-inflammatory agents |
| EP0323727B1 (en) * | 1988-01-06 | 1993-09-01 | UNIROYAL CHEMICAL COMPANY, Inc. | Heterocyclic-alkylene quinoxalinyloxyphenoxy propanoate herbicides |
| US4935530A (en) * | 1988-10-18 | 1990-06-19 | Allergan, Inc. | Process for preparing 5-substituted-3-furaldehydes |
| US5045564A (en) * | 1988-12-07 | 1991-09-03 | Allergan, Inc. | Anti-inflammatory 2-furanones |
| US5112853A (en) * | 1989-11-20 | 1992-05-12 | Allergan, Inc. | Anti-inflammatory furanone compounds |
| US5258400A (en) * | 1989-11-20 | 1993-11-02 | Allergan, Inc. | Anti-inflammatory furanone compounds |
| US5081261A (en) * | 1990-03-23 | 1992-01-14 | Allergan, Inc. | 4-(1-hydroxy-2-N-substituted sulfonamido) ethyl-5-hydroxy-2(5H)-furanones and 4-(N-substituted sulfonamido)-2-ethenyl-5-hydroxy-2(5H)-furanones as anti-inflammatory agents |
| US5013850A (en) * | 1990-03-30 | 1991-05-07 | Allergan, Inc. | 4-ethyl and 4-ethenyl-5-hydroxy-2(5H)-furanones substituted on alpha carbon of the ethyl or ethenyl side chain with a long chain alkyl group and on the beta carbon with a polar group, as anti-inflammatory agents |
| US5183906A (en) * | 1991-04-30 | 1993-02-02 | Allergan, Inc. | 2- and 5-alkyl and phenyl substituted 4-(1-hydroxy, 1-acyloxy or 1-carbamoyloxy)-5-hydroxy-2 (5h)-furanones as anti-inflammatory agents |
| US5225571A (en) * | 1991-04-30 | 1993-07-06 | Allergan, Inc. | Substituted dihydroxy-bis-[5-hydroxy-2(5H)-furanone-4-yl]-alkanes as anti-inflammatory agents |
| US5171864A (en) * | 1991-08-30 | 1992-12-15 | Allergan, Inc. | Di-(5-hydroxy-2(5H)-2-oxo-4-furyl)methyl-alpha,omega alkane-dioates and N,N-bis-(5-hydroxy-2(5H)-2-oxo-4-furyl)methyl-alpha,omega-dialkanoic acid amides as anti-inflammatory agents |
| US5169963A (en) * | 1991-08-30 | 1992-12-08 | Allergan, Inc. | Di-(5-hydroxy-2(5H)2-oxo-4-furyl)alkylmethyl-alpha,omega alkanedioates and N,N-bis-(5-hydroxy-2(5H)2-oxo-4-furyl)alkylmethyl-alpha,omega-dialkanoic acid amides as anti-inflammatory agents |
| US5268387A (en) * | 1992-04-24 | 1993-12-07 | Allergan, Inc. | Pharmaceutical compositions and method for administering 3 and 4-substituted 2(5H)-furanones to a mammal for inhibiting bone loss |
| US5451686A (en) * | 1994-04-15 | 1995-09-19 | Allergan, Inc. | 3 and 5 alkyl and phenyl 4-(hydroxy or acyloxy)-alkyl substituted 2(5H)-furanones as anti-inflammatory agents |
| US5508302A (en) * | 1994-09-28 | 1996-04-16 | American Home Products Corporation | Phospholipase A2 inhibitors |
| KR102038971B1 (ko) * | 2018-03-12 | 2019-11-26 | 주식회사 엔지켐생명과학 | 디아실글리세롤락톤 화합물, 그 제조방법 및 이를 유효성분으로 함유하는 면역증진제 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3472958D1 (en) * | 1983-08-03 | 1988-09-01 | Univ California | Synthetic analgesic and/or anti-inflammatory derivatives of manoalide |
| US4789749A (en) * | 1984-06-18 | 1988-12-06 | The Regents Of The University Of California | Manoalide analogs |
| ZA864674B (en) * | 1985-07-01 | 1988-02-24 | Lilly Co Eli | Furanone derivatives |
-
1988
- 1988-05-18 CA CA000567083A patent/CA1329390C/en not_active Expired - Fee Related
- 1988-05-19 NZ NZ224708A patent/NZ224708A/xx unknown
- 1988-05-26 ZA ZA883758A patent/ZA883758B/xx unknown
- 1988-06-03 AU AU17365/88A patent/AU609139B2/en not_active Ceased
- 1988-06-06 IL IL86633A patent/IL86633A/xx unknown
- 1988-06-07 MY MYPI88000619A patent/MY103301A/en unknown
- 1988-06-07 DE DE8888305189T patent/DE3873428T2/de not_active Expired - Fee Related
- 1988-06-07 NO NO882501A patent/NO173012C/no unknown
- 1988-06-07 AT AT88305189T patent/ATE79115T1/de not_active IP Right Cessation
- 1988-06-07 EP EP88305189A patent/EP0295056B1/en not_active Expired - Lifetime
- 1988-06-07 FI FI882688A patent/FI882688A7/fi not_active IP Right Cessation
- 1988-06-07 ES ES88305189T patent/ES2042742T3/es not_active Expired - Lifetime
- 1988-06-07 HU HU882941A patent/HU204519B/hu not_active IP Right Cessation
- 1988-06-08 KR KR1019880006815A patent/KR890000454A/ko not_active Ceased
- 1988-06-08 CN CN88103421A patent/CN1031839A/zh active Pending
- 1988-06-08 DK DK311288A patent/DK311288A/da not_active Application Discontinuation
- 1988-06-08 PT PT87683A patent/PT87683B/pt not_active IP Right Cessation
- 1988-06-08 JP JP63141457A patent/JPS6413078A/ja active Pending
- 1988-06-08 EG EG317/88A patent/EG18472A/xx active
-
1992
- 1992-10-12 GR GR920402280T patent/GR3005957T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE79115T1 (de) | 1992-08-15 |
| ES2042742T3 (es) | 1993-12-16 |
| CA1329390C (en) | 1994-05-10 |
| ZA883758B (en) | 1989-07-26 |
| DE3873428D1 (de) | 1992-09-10 |
| IL86633A (en) | 1992-12-01 |
| NO882501D0 (no) | 1988-06-07 |
| FI882688A0 (fi) | 1988-06-07 |
| DE3873428T2 (de) | 1993-03-11 |
| EP0295056A1 (en) | 1988-12-14 |
| NZ224708A (en) | 1990-08-28 |
| PT87683B (pt) | 1992-10-30 |
| EP0295056B1 (en) | 1992-08-05 |
| NO173012B (no) | 1993-07-05 |
| CN1031839A (zh) | 1989-03-22 |
| EG18472A (en) | 1993-04-30 |
| AU1736588A (en) | 1988-12-08 |
| GR3005957T3 (enExample) | 1993-06-07 |
| HUT50148A (en) | 1989-12-28 |
| NO882501L (no) | 1988-12-09 |
| NO173012C (no) | 1993-10-13 |
| JPS6413078A (en) | 1989-01-17 |
| HU204519B (en) | 1992-01-28 |
| KR890000454A (ko) | 1989-03-14 |
| DK311288A (da) | 1988-12-09 |
| IL86633A0 (en) | 1988-11-30 |
| DK311288D0 (da) | 1988-06-08 |
| MY103301A (en) | 1993-05-29 |
| PT87683A (pt) | 1988-07-01 |
| AU609139B2 (en) | 1991-04-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application lapsed | ||
| MM | Patent lapsed |
Owner name: ALLERGAN INC. |