ES8707946A1 - Un procedimiento para la preparacion de derivados de furanona. - Google Patents
Un procedimiento para la preparacion de derivados de furanona.Info
- Publication number
- ES8707946A1 ES8707946A1 ES556467A ES556467A ES8707946A1 ES 8707946 A1 ES8707946 A1 ES 8707946A1 ES 556467 A ES556467 A ES 556467A ES 556467 A ES556467 A ES 556467A ES 8707946 A1 ES8707946 A1 ES 8707946A1
- Authority
- ES
- Spain
- Prior art keywords
- furanone derivatives
- alk
- chem
- straight
- double
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/60—Two oxygen atoms, e.g. succinic anhydride
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE FURANONA, DE FORMULA GENERAL (I). CONSISTE EN HACER REACCIONAR UN ALDEHIDO DE FORMULA GENERAL (II), CON ACIDO GLICOXILICO E HIDROCLORURO DE MORFOLINA, EN LAS QUE R1 ES UN RADICAL HIDROCARBONA MONOVALENTE C8-24, DE CADENA LINEAL O RAMIFICADA, QUE CONTIENE ENLACES DOBLES O TRIPLES. DE APLICACION EN EL TRATAMIENTO DE LA INFLAMACION, ASMA, ALERGIAS Y CUALQUIER OTRA ENFERMEDAD RELACIONADA O CAUSADA POR UN EXCESO DE PROSTAGLANDINAS, TROMBOXANOS O LEUCOTRIENOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US75080185A | 1985-07-01 | 1985-07-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES556467A0 ES556467A0 (es) | 1987-09-01 |
ES8707946A1 true ES8707946A1 (es) | 1987-09-01 |
Family
ID=25019225
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES556467A Expired ES8707946A1 (es) | 1985-07-01 | 1986-06-23 | Un procedimiento para la preparacion de derivados de furanona. |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0209274A3 (es) |
JP (1) | JPS625976A (es) |
KR (1) | KR870000908B1 (es) |
CN (1) | CN86104450A (es) |
AU (1) | AU583930B2 (es) |
DK (1) | DK301886A (es) |
ES (1) | ES8707946A1 (es) |
HU (1) | HUT44530A (es) |
IL (1) | IL79212A0 (es) |
NZ (1) | NZ216647A (es) |
PH (1) | PH22938A (es) |
PT (1) | PT82850B (es) |
ZA (1) | ZA864674B (es) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4952605A (en) * | 1983-08-03 | 1990-08-28 | The Regents Of The University Of California | Manoalide analogs |
US4789749A (en) * | 1984-06-18 | 1988-12-06 | The Regents Of The University Of California | Manoalide analogs |
US5171863A (en) * | 1987-06-08 | 1992-12-15 | Allergan, Inc. | Intermediates for preparing 4-substituted 2-5(H)-furanones as anti-inflammatory agents |
US5089485A (en) * | 1988-11-18 | 1992-02-18 | Allergan, Inc. | Anti-inflammatory furanones |
CA1329390C (en) * | 1987-06-08 | 1994-05-10 | John N. Bonfiglio | Anti-inflammatory furanones |
US5037811A (en) * | 1990-04-17 | 1991-08-06 | Allergan, Inc. | 4-(oxygen, sulfur or nitrogen substituted)-methyl 5-hydroxy-2(5H)-furanones as anti-inflammatory agents |
US5081147A (en) * | 1990-03-15 | 1992-01-14 | Allergan, Inc. | 4-(1-hydroxy-2-substituted amino)ethyl-5-hydroxy-2(5H)-furanones as anti-inflammatory agents |
US5059611A (en) * | 1988-11-18 | 1991-10-22 | Allergan, Inc. | Anti-inflammatory 5-hydroxy-2-furanones |
US5134128A (en) * | 1987-06-08 | 1992-07-28 | Allergan, Inc. | Anti-inflammatory furanones |
US5043457A (en) * | 1990-04-17 | 1991-08-27 | Allergan, Inc. | 2(5H)-furanones substituted in the 3 position, as Ca2+ channel antagonists and anti-inflammatory agents |
US5026725A (en) * | 1988-06-06 | 1991-06-25 | American Home Products Corporation | Inhibition of bone loss by 4-substituted-5-hydroxy-2(5H)-furanones |
US4916241A (en) * | 1988-06-06 | 1990-04-10 | American Home Products Corporation | Inhibition of bone loss by 4-substituted-5-hydroxy-2(5H)-furanones |
US4957917A (en) * | 1989-10-25 | 1990-09-18 | Allergan, Inc. | Anti-inflammatory furanones |
US5045564A (en) * | 1988-12-07 | 1991-09-03 | Allergan, Inc. | Anti-inflammatory 2-furanones |
DE3906214A1 (de) * | 1989-02-28 | 1990-08-30 | Boehringer Mannheim Gmbh | Verwendung von macrolactone als antiallergica |
JP2790335B2 (ja) * | 1989-09-20 | 1998-08-27 | 株式会社クラレ | 共役γ―オキシブテノライド化合物およびこれを有効成分とする抗潰瘍剤 |
US5112853A (en) * | 1989-11-20 | 1992-05-12 | Allergan, Inc. | Anti-inflammatory furanone compounds |
US5258400A (en) * | 1989-11-20 | 1993-11-02 | Allergan, Inc. | Anti-inflammatory furanone compounds |
US5081261A (en) * | 1990-03-23 | 1992-01-14 | Allergan, Inc. | 4-(1-hydroxy-2-N-substituted sulfonamido) ethyl-5-hydroxy-2(5H)-furanones and 4-(N-substituted sulfonamido)-2-ethenyl-5-hydroxy-2(5H)-furanones as anti-inflammatory agents |
US5013850A (en) * | 1990-03-30 | 1991-05-07 | Allergan, Inc. | 4-ethyl and 4-ethenyl-5-hydroxy-2(5H)-furanones substituted on alpha carbon of the ethyl or ethenyl side chain with a long chain alkyl group and on the beta carbon with a polar group, as anti-inflammatory agents |
US5183906A (en) * | 1991-04-30 | 1993-02-02 | Allergan, Inc. | 2- and 5-alkyl and phenyl substituted 4-(1-hydroxy, 1-acyloxy or 1-carbamoyloxy)-5-hydroxy-2 (5h)-furanones as anti-inflammatory agents |
US5225571A (en) * | 1991-04-30 | 1993-07-06 | Allergan, Inc. | Substituted dihydroxy-bis-[5-hydroxy-2(5H)-furanone-4-yl]-alkanes as anti-inflammatory agents |
US5171864A (en) * | 1991-08-30 | 1992-12-15 | Allergan, Inc. | Di-(5-hydroxy-2(5H)-2-oxo-4-furyl)methyl-alpha,omega alkane-dioates and N,N-bis-(5-hydroxy-2(5H)-2-oxo-4-furyl)methyl-alpha,omega-dialkanoic acid amides as anti-inflammatory agents |
US5169963A (en) * | 1991-08-30 | 1992-12-08 | Allergan, Inc. | Di-(5-hydroxy-2(5H)2-oxo-4-furyl)alkylmethyl-alpha,omega alkanedioates and N,N-bis-(5-hydroxy-2(5H)2-oxo-4-furyl)alkylmethyl-alpha,omega-dialkanoic acid amides as anti-inflammatory agents |
US5268387A (en) * | 1992-04-24 | 1993-12-07 | Allergan, Inc. | Pharmaceutical compositions and method for administering 3 and 4-substituted 2(5H)-furanones to a mammal for inhibiting bone loss |
US5451686A (en) * | 1994-04-15 | 1995-09-19 | Allergan, Inc. | 3 and 5 alkyl and phenyl 4-(hydroxy or acyloxy)-alkyl substituted 2(5H)-furanones as anti-inflammatory agents |
JP5381942B2 (ja) | 2010-09-17 | 2014-01-08 | オムロンヘルスケア株式会社 | 電子体温計およびその製造方法 |
SG11202102873WA (en) | 2018-09-25 | 2021-04-29 | Schlumberger Technology Bv | Piston load ring seal configurations |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57149283A (en) * | 1981-03-09 | 1982-09-14 | Fujisawa Pharmaceut Co Ltd | Long-chain fatty acid lactol |
DE3472958D1 (en) * | 1983-08-03 | 1988-09-01 | Univ California | Synthetic analgesic and/or anti-inflammatory derivatives of manoalide |
US4447445A (en) * | 1983-08-03 | 1984-05-08 | The Regents Of The University Of Calif. | Manoalide, an anti-inflammatory analgesic marine natural product |
US4616089A (en) * | 1983-08-03 | 1986-10-07 | University Of California | Synthetic anti-inflammatory derivatives of manoalide |
US4789749A (en) * | 1984-06-18 | 1988-12-06 | The Regents Of The University Of California | Manoalide analogs |
-
1986
- 1986-06-23 ZA ZA864674A patent/ZA864674B/xx unknown
- 1986-06-23 ES ES556467A patent/ES8707946A1/es not_active Expired
- 1986-06-24 IL IL79212A patent/IL79212A0/xx unknown
- 1986-06-24 NZ NZ216647A patent/NZ216647A/xx unknown
- 1986-06-24 PH PH33941A patent/PH22938A/en unknown
- 1986-06-25 EP EP86304907A patent/EP0209274A3/en not_active Ceased
- 1986-06-26 DK DK301886A patent/DK301886A/da not_active Application Discontinuation
- 1986-06-26 PT PT82850A patent/PT82850B/pt unknown
- 1986-06-27 AU AU59343/86A patent/AU583930B2/en not_active Expired - Fee Related
- 1986-06-30 CN CN198686104450A patent/CN86104450A/zh active Pending
- 1986-06-30 JP JP61154966A patent/JPS625976A/ja active Pending
- 1986-06-30 KR KR1019860005263A patent/KR870000908B1/ko not_active IP Right Cessation
- 1986-06-30 HU HU862729A patent/HUT44530A/hu unknown
Also Published As
Publication number | Publication date |
---|---|
IL79212A0 (en) | 1986-09-30 |
CN86104450A (zh) | 1986-12-31 |
PT82850B (en) | 1988-05-06 |
HUT44530A (en) | 1988-03-28 |
NZ216647A (en) | 1989-04-26 |
JPS625976A (ja) | 1987-01-12 |
KR870000908B1 (ko) | 1987-05-06 |
KR870001187A (ko) | 1987-03-12 |
AU583930B2 (en) | 1989-05-11 |
ES556467A0 (es) | 1987-09-01 |
EP0209274A3 (en) | 1987-07-22 |
AU5934386A (en) | 1987-01-08 |
DK301886A (da) | 1987-01-02 |
PH22938A (en) | 1989-02-03 |
ZA864674B (en) | 1988-02-24 |
EP0209274A2 (en) | 1987-01-21 |
PT82850A (en) | 1986-07-01 |
DK301886D0 (da) | 1986-06-26 |
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