FI881020A - Foerfarande foer framstaellning av till sina egenskaper foerbaettrad ifosfamid. - Google Patents
Foerfarande foer framstaellning av till sina egenskaper foerbaettrad ifosfamid. Download PDFInfo
- Publication number
- FI881020A FI881020A FI881020A FI881020A FI881020A FI 881020 A FI881020 A FI 881020A FI 881020 A FI881020 A FI 881020A FI 881020 A FI881020 A FI 881020A FI 881020 A FI881020 A FI 881020A
- Authority
- FI
- Finland
- Prior art keywords
- egenskaper
- foerbaettrad
- ifosfamid
- sina
- till
- Prior art date
Links
- HOMGKSMUEGBAAB-UHFFFAOYSA-N ifosfamide Chemical compound ClCCNP1(=O)OCCCN1CCCl HOMGKSMUEGBAAB-UHFFFAOYSA-N 0.000 title abstract 2
- 229960001101 ifosfamide Drugs 0.000 title abstract 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- ZAFNJMIOTHYJRJ-UHFFFAOYSA-N Diisopropyl ether Chemical compound CC(C)OC(C)C ZAFNJMIOTHYJRJ-UHFFFAOYSA-N 0.000 abstract 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- 239000011877 solvent mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
- C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
- C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
- C07F9/65846—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring the phosphorus atom being part of a six-membered ring which may be condensed with another ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Cephalosporin Compounds (AREA)
- Materials For Medical Uses (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Detergent Compositions (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3707154 | 1987-03-06 | ||
| DE3707154 | 1987-03-06 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI881020A0 FI881020A0 (fi) | 1988-03-04 |
| FI881020A true FI881020A (fi) | 1988-09-07 |
| FI86187B FI86187B (fi) | 1992-04-15 |
| FI86187C FI86187C (fi) | 1992-07-27 |
Family
ID=6322382
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI881020A FI86187C (fi) | 1987-03-06 | 1988-03-04 | Foerfarande foer framstaellning av ifosfamid med foerbaettrade egenskaper. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4882452A (fi) |
| EP (1) | EP0281832B1 (fi) |
| JP (1) | JPS63230697A (fi) |
| AT (1) | ATE63121T1 (fi) |
| CA (1) | CA1305970C (fi) |
| DE (1) | DE3862595D1 (fi) |
| DK (1) | DK168822B1 (fi) |
| ES (1) | ES2021771B3 (fi) |
| FI (1) | FI86187C (fi) |
| GR (1) | GR3001898T3 (fi) |
| IE (1) | IE60474B1 (fi) |
| PT (1) | PT86892B (fi) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5227373A (en) * | 1991-10-23 | 1993-07-13 | Bristol-Myers Squibb Co. | Lyophilized ifosfamide compositions |
| US5958462A (en) * | 1997-05-23 | 1999-09-28 | Mclean; Linsey | Therapeutic bath salts and method of use |
| US5972912A (en) * | 1998-12-17 | 1999-10-26 | S.P. Pharmaceuticals | Method for lyophilizing ifosfamide |
| US6613927B1 (en) | 2002-02-08 | 2003-09-02 | American Pharmaceutical Partners, Inc. | Sterile lyophilized ifosfamide and associated methods |
| DK1667655T3 (da) * | 2003-10-01 | 2011-10-24 | Baxter Int | Ny anvendelse, farmaceutiske præparater og en fremgangsmåde til deres fremstilling |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3732340A (en) * | 1966-07-11 | 1973-05-08 | Asta Werke Ag Chem Fab | N',o-propylene phosphoric acid ester diamides |
| DE1645921C3 (de) * | 1966-07-11 | 1978-10-12 | Asta-Werke Ag Chemische Fabrik, 4800 Bielefeld | 2-Oxo-13,2-osazaphosphorinane, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate |
-
1988
- 1988-02-23 DE DE8888102612T patent/DE3862595D1/de not_active Expired - Lifetime
- 1988-02-23 AT AT88102612T patent/ATE63121T1/de not_active IP Right Cessation
- 1988-02-23 ES ES88102612T patent/ES2021771B3/es not_active Expired - Lifetime
- 1988-02-23 EP EP88102612A patent/EP0281832B1/de not_active Expired - Lifetime
- 1988-03-03 PT PT86892A patent/PT86892B/pt active IP Right Revival
- 1988-03-03 US US07/163,586 patent/US4882452A/en not_active Expired - Lifetime
- 1988-03-04 FI FI881020A patent/FI86187C/fi not_active IP Right Cessation
- 1988-03-04 JP JP63049949A patent/JPS63230697A/ja active Granted
- 1988-03-04 IE IE63588A patent/IE60474B1/en not_active IP Right Cessation
- 1988-03-04 DK DK116988A patent/DK168822B1/da not_active IP Right Cessation
- 1988-03-04 CA CA000560639A patent/CA1305970C/en not_active Expired - Lifetime
-
1991
- 1991-05-03 GR GR91400540T patent/GR3001898T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK116988D0 (da) | 1988-03-04 |
| DE3862595D1 (de) | 1991-06-06 |
| DK116988A (da) | 1988-09-07 |
| DK168822B1 (da) | 1994-06-20 |
| ATE63121T1 (de) | 1991-05-15 |
| FI881020A0 (fi) | 1988-03-04 |
| EP0281832B1 (de) | 1991-05-02 |
| FI86187C (fi) | 1992-07-27 |
| FI86187B (fi) | 1992-04-15 |
| PT86892B (pt) | 1992-05-29 |
| JPH0563479B2 (fi) | 1993-09-10 |
| PT86892A (pt) | 1988-04-01 |
| ES2021771B3 (es) | 1991-11-16 |
| JPS63230697A (ja) | 1988-09-27 |
| IE880635L (en) | 1988-09-06 |
| GR3001898T3 (en) | 1992-11-23 |
| IE60474B1 (en) | 1994-07-13 |
| EP0281832A1 (de) | 1988-09-14 |
| US4882452A (en) | 1989-11-21 |
| CA1305970C (en) | 1992-08-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Patent granted |
Owner name: ASTA MEDICA AKTIENGESELLSCHAFT |
|
| MA | Patent expired |