FI875455A - Renin-inhibitorer iii. - Google Patents

Renin-inhibitorer iii. Download PDF

Info

Publication number
FI875455A
FI875455A FI875455A FI875455A FI875455A FI 875455 A FI875455 A FI 875455A FI 875455 A FI875455 A FI 875455A FI 875455 A FI875455 A FI 875455A FI 875455 A FI875455 A FI 875455A
Authority
FI
Finland
Prior art keywords
renin inhibitor
inhibitor iii
iii
renin
inhibitor
Prior art date
Application number
FI875455A
Other languages
English (en)
Finnish (fi)
Other versions
FI875455A0 (fi
Inventor
James Perry Hudspeth
James Stanley Kaltenbronn
Joseph Thomas Repine
William Howard Roark
Michael Andrew Stier
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/941,966 external-priority patent/US4735933A/en
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of FI875455A0 publication Critical patent/FI875455A0/fi
Publication of FI875455A publication Critical patent/FI875455A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/14Angiotensins: Related peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/56Amides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/86Renin inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FI875455A 1986-12-15 1987-12-11 Renin-inhibitorer iii. FI875455A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/941,966 US4735933A (en) 1986-12-15 1986-12-15 Renin inhibitors III
US07/113,277 US4895834A (en) 1986-12-15 1987-11-02 Renin inhibitors III

Publications (2)

Publication Number Publication Date
FI875455A0 FI875455A0 (fi) 1987-12-11
FI875455A true FI875455A (fi) 1988-06-16

Family

ID=26810874

Family Applications (1)

Application Number Title Priority Date Filing Date
FI875455A FI875455A (fi) 1986-12-15 1987-12-11 Renin-inhibitorer iii.

Country Status (10)

Country Link
US (1) US4895834A (de)
EP (1) EP0271862A3 (de)
KR (1) KR880007562A (de)
AU (1) AU605212B2 (de)
DK (1) DK651087A (de)
FI (1) FI875455A (de)
NO (1) NO875199L (de)
NZ (1) NZ222754A (de)
PH (2) PH23734A (de)
PT (1) PT86374B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4921855A (en) * 1987-06-22 1990-05-01 Fujisawa Pharmaceutical Co., Ltd. New Histidyl amino acid derivatives, and pharmaceutical composition comprising the same
ATE107658T1 (de) * 1988-01-26 1994-07-15 Sankyo Co Renin inhibierende polypeptide, ihre herstellung und anwendung.
DE3915755A1 (de) * 1989-05-13 1990-11-29 Bayer Ag Fungizide mittel sowie substituierte aminosaeureamid-derivate und deren herstellung
ES2097208T3 (es) 1990-05-11 1997-04-01 Pfizer Composiciones y procedimientos terapeuticos y sinergicos.
US5821232A (en) * 1990-05-11 1998-10-13 Pfizer Inc. Synergistic therapeutic compositions and methods
US5244910A (en) * 1990-08-15 1993-09-14 Abbott Laboratories Renin inhibitors
US5258362A (en) * 1991-06-11 1993-11-02 Abbott Laboratories Renin inhibiting compounds
US5212185A (en) * 1992-08-14 1993-05-18 G. D. Searle & Co. Piperidinyl-terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension
US5780494A (en) * 1994-11-14 1998-07-14 G. D. Searle & Co. Piperidinyl-terminated alkylamino ethynl alanine amino diol compounds for treatment of hypertension
EP1723962A1 (de) * 2005-05-19 2006-11-22 IMBA-Institut für Molekulare Biotechnologie GmbH Gebrauch der Hemmnisse des Renin-angiotensinsystems für die Behandlung der Lungenverletzungen

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0114993B1 (de) * 1982-12-27 1990-05-16 Merck & Co. Inc. Reninhemmende Tripeptide
EP0173481A3 (de) * 1984-08-06 1988-12-21 The Upjohn Company Peptide
SU1676454A3 (ru) * 1984-11-30 1991-09-07 Санкио Компани Лимитед (Фирма) Способ получени пептидов или их фармацевтически приемлемых солей
KR870005013A (ko) * 1985-11-29 1987-06-04 가와무라 요시부미 레닌-억제 올리고펩티드, 그의 제조방법 및 용도
US4735933A (en) * 1986-12-15 1988-04-05 Warner-Lambert Company Renin inhibitors III
NZ222755A (en) * 1986-12-23 1989-11-28 Warner Lambert Co Renin inhibiting acyl peptide derivatives containing two to four amino acid residues, and pharmaceutical compositions
FI89058C (fi) * 1987-02-27 1993-08-10 Yamanouchi Pharma Co Ltd Foerfarande foer framstaellning av som remin-inhibitorer anvaenda 2-(l-alanyl-l-histidylamino)-butanol-derivat
DK523288A (da) * 1987-10-06 1989-04-07 Hoffmann La Roche Aminosyrederivater

Also Published As

Publication number Publication date
NO875199L (no) 1988-06-16
EP0271862A2 (de) 1988-06-22
PH24655A (en) 1990-09-07
AU8207287A (en) 1988-06-30
PH23734A (en) 1989-11-03
PT86374B (pt) 1990-11-20
NZ222754A (en) 1989-12-21
EP0271862A3 (de) 1990-11-14
US4895834A (en) 1990-01-23
AU605212B2 (en) 1991-01-10
KR880007562A (ko) 1988-08-27
FI875455A0 (fi) 1987-12-11
NO875199D0 (no) 1987-12-14
DK651087D0 (da) 1987-12-11
DK651087A (da) 1988-06-16
PT86374A (en) 1988-01-01

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: WARNER-LAMBERT COMPANY