FI874459A0 - Förfarande för framställning av terapeutiskt användbara piperidinderivat - Google Patents

Förfarande för framställning av terapeutiskt användbara piperidinderivat

Info

Publication number
FI874459A0
FI874459A0 FI874459A FI874459A FI874459A0 FI 874459 A0 FI874459 A0 FI 874459A0 FI 874459 A FI874459 A FI 874459A FI 874459 A FI874459 A FI 874459A FI 874459 A0 FI874459 A0 FI 874459A0
Authority
FI
Finland
Prior art keywords
preparation
therapeutically useful
piperidine derivatives
useful piperidine
derivatives
Prior art date
Application number
FI874459A
Other languages
English (en)
Finnish (fi)
Other versions
FI874459A (sv
FI92821C (sv
FI92821B (sv
Inventor
Jorgen Drejer
Palle Jakobsen
Original Assignee
Ferrosan As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK523286A external-priority patent/DK523286D0/da
Priority claimed from DK323487A external-priority patent/DK323487D0/da
Application filed by Ferrosan As filed Critical Ferrosan As
Publication of FI874459A0 publication Critical patent/FI874459A0/sv
Publication of FI874459A publication Critical patent/FI874459A/sv
Application granted granted Critical
Publication of FI92821B publication Critical patent/FI92821B/sv
Publication of FI92821C publication Critical patent/FI92821C/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI874459A 1986-11-03 1987-10-09 Förfarande för framställning av terapeutiskt användbara piperidinderivat FI92821C (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DK523286A DK523286D0 (da) 1986-11-03 1986-11-03 Piperidine forbindelser, deres fremstilling og anvendelse
DK523286 1986-11-03
DK323487 1987-06-25
DK323487A DK323487D0 (da) 1987-06-25 1987-06-25 Piperidin forbindelser, deres fremstilling og anvendelse

Publications (4)

Publication Number Publication Date
FI874459A0 true FI874459A0 (sv) 1987-10-09
FI874459A FI874459A (sv) 1988-05-04
FI92821B FI92821B (sv) 1994-09-30
FI92821C FI92821C (sv) 1995-01-10

Family

ID=26066954

Family Applications (1)

Application Number Title Priority Date Filing Date
FI874459A FI92821C (sv) 1986-11-03 1987-10-09 Förfarande för framställning av terapeutiskt användbara piperidinderivat

Country Status (14)

Country Link
US (3) US4877799A (sv)
EP (1) EP0266574B1 (sv)
JP (1) JP2633872B2 (sv)
KR (1) KR880006193A (sv)
AU (1) AU602735B2 (sv)
CA (1) CA1323367C (sv)
DE (1) DE3788709T2 (sv)
ES (1) ES2061463T3 (sv)
FI (1) FI92821C (sv)
IE (1) IE66332B1 (sv)
IL (1) IL84021A (sv)
NZ (1) NZ222155A (sv)
PH (1) PH24749A (sv)
PT (1) PT86066B (sv)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5017585A (en) * 1986-11-03 1991-05-21 Novo Nordisk A/S Method of treating calcium overload
IE66332B1 (en) * 1986-11-03 1995-12-27 Novo Nordisk As Piperidine compounds and their preparation and use
DK231088D0 (da) * 1988-04-28 1988-04-28 Ferrosan As Piperidinforbindelser, deres fremstilling og anvendelse
AT391269B (de) * 1988-12-30 1990-09-10 Burghart Kurt Pharmazeutische zubereitung
DK640289D0 (da) * 1989-12-18 1989-12-18 Ferrosan As Ny heterocyklisk kemi
IL98757A (en) * 1990-07-18 1997-01-10 Novo Nordisk As Piperidine derivatives their preparation and pharmaceutical compositions containing them
GB9226111D0 (en) * 1992-12-15 1993-02-10 Smithkline Beecham Plc Madicaments
ES2102295B1 (es) * 1994-03-18 1998-04-01 Ferrer Int Nuevos compuestos derivados de la n-benzoilmetil-piperidina.
HUP9602977A3 (en) * 1995-02-28 1998-01-28 Daiichi Asubio Pharma Co Ltd Arylpiperidine and arylpiperazine derivatives and drugs containing the same
JPH11505229A (ja) * 1995-05-17 1999-05-18 ノボ ノルディスク アクティーゼルスカブ ４−アリール−ピペリジン誘導体を製造する方法
US6025355A (en) 1997-05-19 2000-02-15 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
JP3446468B2 (ja) 1996-04-15 2003-09-16 旭硝子株式会社 ピペリジンカルビノール類の製造方法
JP3882224B2 (ja) 1996-05-31 2007-02-14 旭硝子株式会社 パロキセチンの製造方法
DE69739561D1 (de) 1996-06-13 2009-10-15 Sumitomo Chemical Co Piperidin Derivative als Zwischenprodukte zur Herstellung von Paroxetine und Verfahren zu ihrer Herstellung
WO1998003172A1 (fr) * 1996-07-22 1998-01-29 Suntory Limited Derives arylpiperidinol et arylpiperidine et medicaments les contenant
CA2231879C (en) * 1996-07-22 2007-01-23 Suntory Limited Arylpiperidinol and arylpiperidine derivatives and pharmaceuticals containing the same
US6242198B1 (en) 1996-07-25 2001-06-05 Cambridge Neuroscience, Inc. Methods of treatment of eye trauma and disorders
US6756389B2 (en) 1996-08-09 2004-06-29 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
US6110937A (en) * 1997-04-03 2000-08-29 Syntex Usa, Inc. Phenoxymethyl piperidine derivatives for the treatment of neuropathic pain
WO1998045263A1 (en) * 1997-04-07 1998-10-15 Georgetown University Analogs of cocaine
AU3108097A (en) * 1997-06-10 1998-12-30 Synthon B.V. 4-phenylpiperidine compounds
CH689805A8 (fr) * 1998-07-02 2000-02-29 Smithkline Beecham Plc Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant.
AU9087301A (en) 2000-09-11 2002-03-26 Sepracor Inc Ligands for monoamine receptors and transporters, and methods of use thereof
US7294637B2 (en) 2000-09-11 2007-11-13 Sepracor, Inc. Method of treating addiction or dependence using a ligand for a monamine receptor or transporter
US6777554B2 (en) 2001-02-05 2004-08-17 Teva Pharmaceutical Industries Ltd. Preparation of N-methylparoxetine and related intermediate compounds
AU2004285497B2 (en) * 2003-10-22 2009-10-22 Georgetown University Dopamine-, norepinephrine- and serotonin- transporter- selective heterocyclic compounds and their therapeutic applications
US20070142389A1 (en) * 2005-12-20 2007-06-21 Pfizer Inc. Piperidine derivatives

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1203149A (en) * 1968-06-10 1970-08-26 Ici Ltd Piperidine derivatives
GB1422263A (en) * 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
DE2549999A1 (de) * 1975-11-07 1977-05-12 Boehringer Mannheim Gmbh Piperidin-derivate und verfahren zu ihrer herstellung
DK149624C (da) * 1983-03-07 1987-02-02 Ferrosan As Fremgangsmaade til fremstilling af (+)-trans-3-((4-methoxyphenoxy)-methyl)-1-methyl-4-phenylpiperidin eller et farmaceutisk acceptabelt salt heraf ud fra en blanding af enantiomererne
US4593036A (en) * 1984-02-07 1986-06-03 A/S Ferrosan (-)-Trans-4-(4-fluorophenyl)-3-[(4-methoxyphenoxy)methyl]-1-methylpiperidine useful as 5-HT potentiator
US4585777A (en) * 1984-02-07 1986-04-29 A/S Ferrosan (-)-Trans-4-(4-fluorophenyl)-3-(4-methoxyphenoxy)methylpiperidine for potentiating 5-HT
GB8431478D0 (en) * 1984-12-13 1985-01-23 Beecham Group Plc Compounds
ES2058061T3 (es) * 1985-10-25 1994-11-01 Beecham Group Plc Derivado de piperidina, su preparacion y su uso como medicamento.
IE66332B1 (en) * 1986-11-03 1995-12-27 Novo Nordisk As Piperidine compounds and their preparation and use

Also Published As

Publication number Publication date
NZ222155A (en) 1990-08-28
IE872561L (en) 1988-05-03
JP2633872B2 (ja) 1997-07-23
US5019582A (en) 1991-05-28
IL84021A0 (en) 1988-02-29
EP0266574B1 (en) 1994-01-05
IL84021A (en) 1993-02-21
US4877799A (en) 1989-10-31
CA1323367C (en) 1993-10-19
PT86066B (pt) 1990-11-07
AU8048287A (en) 1988-05-05
IE66332B1 (en) 1995-12-27
AU602735B2 (en) 1990-10-25
JPS63126866A (ja) 1988-05-30
PT86066A (en) 1987-12-01
FI874459A (sv) 1988-05-04
PH24749A (en) 1990-10-01
EP0266574A3 (en) 1988-07-20
DE3788709T2 (de) 1994-04-28
DE3788709D1 (de) 1994-02-17
KR880006193A (ko) 1988-07-22
EP0266574A2 (en) 1988-05-11
ES2061463T3 (es) 1994-12-16
FI92821C (sv) 1995-01-10
US4985446A (en) 1991-01-15
FI92821B (sv) 1994-09-30

Similar Documents

Publication Publication Date Title
FI874459A0 (sv) Förfarande för framställning av terapeutiskt användbara piperidinderivat
FI92934B (sv) Analogiförfarande för framställning av terapeutiskt användbara 1-deoxinojirimycinderivat
FI90346C (sv) Förfarande för framställning av terapeutiskt användbara nor-statin- och nor-cyklostatin derivat
FI883064A0 (sv) Förfarande för framställning av terapeutiskt användbara heterocykliska föreningar
FI890282A (sv) Förfarande för framställning av terapeutiskt användbara 23,24-didehydro-25-hydroxikalciferolderivat
FI95704B (sv) Förfarande för framställning av nya terapeutiskt användbara pyridinderivat
FI90769C (sv) Förfarande för framställning av terapeutiskt användbara triazolföreningar
FI892182A0 (sv) Förfarande för framställning av terapeutiskt användbara kromanderivat
FI850654A0 (sv) Förfarande för framställning av terapeutiskt användbara pleuromutilinderivator
FI94752C (sv) Förfarande för framställning av terapeutiskt användbara propenonoximetrar
FI93215C (sv) Förfarande för framställning av terapeutiskt användbara aminoalkoxifenylderivat
FI873350A (sv) Förfarande för framställning av terapeutiskt användbara 1,4-dihydropyridinderivat
FI884910A (sv) Förfarande för framställning av terapeutiskt användbart bensopyranderivat
FI884471A0 (sv) Förfarande för framställning av terapeutiskt aktiva dihydropyridinföreningar
FI880467A (sv) Förfarande för framställning av terapeutiskt användbara substituerade 3,4-dihydro-2H-benzopyraner
FI892948A (sv) Förfarande för framställning av terapeutiskt användbara kromanderivat
FI92065C (sv) Förfarande för framställning av farmaceutiska piperidinderivat
FI893003A0 (sv) Förfarande för framställning av terapeutiskt användbara neplanocinderivat
FI903077A0 (sv) Förfarande för framställning av terapeutiskt aktiva R(-)-3-kinuklidinolderivat
FI92188C (sv) Förfarande för framställning av terapeutiskt användbara fenoxialkylpyrokatekolderivat
FI94351B (sv) Förfarande för framställning av terapeutiskt användbara peptidderivater
FI886066A (sv) Förfarande för framställning av nya terapeutiskt användbara substituerade styrenderivat
PT88158A (pt) Process for the preparation of a novel diosmin derivative
FI893434A0 (sv) Förfarande för framställning av nya terapeutiskt användbara cykloalkyltiazolderivat
FI892144A0 (sv) Förfarande för framställning av 5-C-hydroximetylaldohexosbaserade föreningar

Legal Events

Date Code Title Description
BB Publication of examined application
MM Patent lapsed
MM Patent lapsed

Owner name: NOVO NORDISK A/S