FI864423A - N-substituerade-n-/3-(1,2,4-triazolo /4,3-b-/pyridazin-6-yl)fenyl/alkanamider, karbamater och urreas - Google Patents

N-substituerade-n-/3-(1,2,4-triazolo /4,3-b-/pyridazin-6-yl)fenyl/alkanamider, karbamater och urreas Download PDF

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Publication number
FI864423A
FI864423A FI864423A FI864423A FI864423A FI 864423 A FI864423 A FI 864423A FI 864423 A FI864423 A FI 864423A FI 864423 A FI864423 A FI 864423A FI 864423 A FI864423 A FI 864423A
Authority
FI
Finland
Prior art keywords
urreas
substituerade
alkanamide
pyridazin
triazolo
Prior art date
Application number
FI864423A
Other languages
English (en)
Other versions
FI864423A0 (fi
Inventor
Jay Donald Albright
Dannis William Powell
John Paul Dusza
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of FI864423A0 publication Critical patent/FI864423A0/fi
Publication of FI864423A publication Critical patent/FI864423A/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI864423A 1985-10-31 1986-10-30 N-substituerade-n-/3-(1,2,4-triazolo /4,3-b-/pyridazin-6-yl)fenyl/alkanamider, karbamater och urreas FI864423A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/793,437 US4654343A (en) 1985-10-31 1985-10-31 N-substituted-N[3-(1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl]alkanamides, carbamates and ureas

Publications (2)

Publication Number Publication Date
FI864423A0 FI864423A0 (fi) 1986-10-30
FI864423A true FI864423A (fi) 1987-05-01

Family

ID=25159919

Family Applications (1)

Application Number Title Priority Date Filing Date
FI864423A FI864423A (fi) 1985-10-31 1986-10-30 N-substituerade-n-/3-(1,2,4-triazolo /4,3-b-/pyridazin-6-yl)fenyl/alkanamider, karbamater och urreas

Country Status (12)

Country Link
US (1) US4654343A (fi)
EP (1) EP0223974A1 (fi)
JP (1) JPS62108882A (fi)
KR (1) KR900004833B1 (fi)
AU (1) AU591940B2 (fi)
DK (1) DK519486A (fi)
ES (1) ES2002430A6 (fi)
FI (1) FI864423A (fi)
HU (1) HU196209B (fi)
NO (1) NO165194C (fi)
NZ (1) NZ218063A (fi)
ZA (1) ZA868280B (fi)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4892873A (en) * 1985-10-31 1990-01-09 American Cyanamid Company N-substituted -N-(3-(1,2,4-triazolo-(4,3-b)pyridazin-6-yl)phenyl)alkanamides, carbamates and ureas
GB9507348D0 (en) * 1995-04-08 1995-05-31 Knoll Ag Therapeutic agents
US20100210590A1 (en) * 1995-09-27 2010-08-19 Northwestern University Compositions and treatments for seizure-related disorders
GB9718254D0 (en) * 1997-08-28 1997-11-05 Merck Sharp & Dohme Therapeutic agents
US6297235B1 (en) * 1997-08-28 2001-10-02 Merck Sharp & Dohme Ltd. Triazolopyridazine derivatives for treating anxiety and enhancing cognition
GB9726702D0 (en) * 1997-12-18 1998-02-18 Merck Sharp & Dohme Therapeutic use
GB9723999D0 (en) 1997-11-13 1998-01-14 Merck Sharp & Dohme Therapeutic use
GB9726701D0 (en) * 1997-12-18 1998-02-18 Merck Sharp & Dohme Therapeutic use
GB9726699D0 (en) * 1997-12-18 1998-02-18 Merck Sharp & Dohme Therapeutic use
US6110915A (en) * 1997-12-18 2000-08-29 Merck & Co., Inc. Antiemetic use of triazolo-pyridazine derivatives
WO1999036423A1 (en) * 1998-01-14 1999-07-22 Merck Sharp & Dohme Limited Triazolo-pyridazine derivatives as ligands for gaba receptors
GB9801234D0 (en) 1998-01-21 1998-03-18 Merck Sharp & Dohme Therapeutic agents
US6579875B1 (en) * 1998-01-21 2003-06-17 Merck Sharp & Dohme Limited Triazolo-pyridazine derivatives as ligands for GABA receptors
GB9801210D0 (en) 1998-01-21 1998-03-18 Merck Sharp & Dohme Therapeutic agents
GB9801202D0 (en) 1998-01-21 1998-03-18 Merck Sharp & Dohme Therapeutic agents
GB9801208D0 (en) 1998-01-21 1998-03-18 Merck Sharp & Dohme Therapeutic agents
GB9801397D0 (en) 1998-01-22 1998-03-18 Merck Sharp & Dohme Therapeutic agents
GB9801538D0 (en) 1998-01-23 1998-03-25 Merck Sharp & Dohme Pharmaceutical product
TWI334868B (en) * 2003-06-03 2010-12-21 Nippon Kayaku Kk [1,2,4] triazoro [1,5-a] pyrimidine-2-ylurea derivative and use thereof
KR100658771B1 (ko) * 2004-05-31 2006-12-15 고려대학교 산학협력단 고추 유래의 ＣａＯＤＣ1 유전자 도입 재조합 벡터 및이를 이용하여 형질전환된 식물병 저항성 향상 담배 변종식물체
WO2006050359A2 (en) * 2004-11-02 2006-05-11 Northwestern University Pyridazine compounds and methods
ES2543813T3 (es) 2004-11-02 2015-08-24 Northwestern University Compuestos de piridazina para el tratamiento de enfermedades inflamatorias
TW200719895A (en) * 2005-05-26 2007-06-01 Wyeth Corp Method for the treatment of noise phobia in companion animals
WO2007127375A2 (en) 2006-04-28 2007-11-08 Northwestern University Formulations containing pyridazine compounds for treating neuroinflammatory diseases
CA2650711A1 (en) * 2006-04-28 2007-11-08 Northwestern University Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
EP2015751A2 (en) * 2006-04-28 2009-01-21 Northwestern University Salts of pyridazine compounds
JP2010520223A (ja) * 2007-03-02 2010-06-10 ノースウェスタン ユニバーシティ 発作関連障害のための組成物および方法
US8188083B2 (en) * 2007-06-28 2012-05-29 Abbott Laboratories Triazolopyridazines
PT2464645T (pt) * 2009-07-27 2017-10-11 Gilead Sciences Inc Compostos heterocíclicos fusionados como moduladores do canal de iões
BR112012033402A2 (pt) 2010-07-02 2017-01-24 Gilead Sciences Inc moduladores de canais de íons conforme os compostos heterocíclicos fundidos
BR112013028886A2 (pt) 2011-05-10 2016-08-09 Gilead Sciences Inc compostos heterocíclicos fundidos como moduladores dde canal de sódio
NO3175985T3 (fi) 2011-07-01 2018-04-28
UY34171A (es) 2011-07-01 2013-01-31 Gilead Sciences Inc Compuestos heterocíclicos fusionados como moduladores del canal iónico
CN112225741B (zh) * 2020-12-09 2021-03-30 中山大学 1,2,4三唑并4,3-b哒嗪衍生物在制备抗炎症因子风暴药物中的应用
WO2024074483A1 (en) * 2022-10-04 2024-04-11 Eth Zurich Compounds for the treatment of myotonic dystrophy

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1080712A (en) * 1976-09-22 1980-07-01 Jay D. Albright Hypotensive agents
US4230705A (en) * 1976-09-22 1980-10-28 American Cyanamid Company 6-Phenyl-1,2,4-triazolo[4,3-b]pyridazines and their uses in treating anxiety
US4112095A (en) * 1976-10-07 1978-09-05 American Cyanamid Company 6-Phenyl-1,2,4-triazolo[4,3-b]pyridazine hypotensive agents
PH12424A (en) * 1976-10-26 1979-02-15 American Cyanamid Co Method of treating anxiety in mammals
US4260755A (en) * 1979-10-31 1981-04-07 American Cyanamid Company Novel 6-phenyl and substituted 6-phenyl-1,2,4-triazolo[4,3-b]pyridazines
DE3217325A1 (de) * 1982-05-08 1983-11-10 Hoechst Ag, 6230 Frankfurt 3-amino-6-aryl-1,2,4-triazolo(4,3-b)-pyridazine, ihre herstellung und ihre verwendung
DE3311753A1 (de) * 1983-03-31 1984-10-04 Hoechst Ag, 6230 Frankfurt Substituierte 6-aryl-1,2,4-triazolo(4,3-b)pyridazine - ihre herstellung und verwendung -

Also Published As

Publication number Publication date
AU6454986A (en) 1987-05-07
ES2002430A6 (es) 1988-08-01
US4654343A (en) 1987-03-31
ZA868280B (en) 1987-06-24
HU196209B (en) 1988-10-28
NO864336D0 (no) 1986-10-30
JPS62108882A (ja) 1987-05-20
NO864336L (no) 1987-05-04
HUT43609A (en) 1987-11-30
EP0223974A1 (en) 1987-06-03
DK519486A (da) 1987-05-01
NO165194C (no) 1991-01-09
AU591940B2 (en) 1989-12-21
KR900004833B1 (ko) 1990-07-07
DK519486D0 (da) 1986-10-30
NO165194B (no) 1990-10-01
KR870004034A (ko) 1987-05-07
FI864423A0 (fi) 1986-10-30
NZ218063A (en) 1990-03-27

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FD Application lapsed

Owner name: AMERICAN CYANAMID COMPANY