FI864423A0 - N-substituerade-n-/3-(1,2,4-triazolo /4,3-b-/pyridazin-6-yl)fenyl/alkanamider, karbamater och urreas. - Google Patents

N-substituerade-n-/3-(1,2,4-triazolo /4,3-b-/pyridazin-6-yl)fenyl/alkanamider, karbamater och urreas.

Info

Publication number
FI864423A0
FI864423A0 FI864423A FI864423A FI864423A0 FI 864423 A0 FI864423 A0 FI 864423A0 FI 864423 A FI864423 A FI 864423A FI 864423 A FI864423 A FI 864423A FI 864423 A0 FI864423 A0 FI 864423A0
Authority
FI
Finland
Prior art keywords
urreas
alkanamider
substituerade
pyridazin
triazolo
Prior art date
Application number
FI864423A
Other languages
English (en)
Other versions
FI864423A (fi
Inventor
Jay Donald Albright
Dannis William Powell
John Paul Dusza
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of FI864423A0 publication Critical patent/FI864423A0/fi
Publication of FI864423A publication Critical patent/FI864423A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI864423A 1985-10-31 1986-10-30 N-substituerade-n-/3-(1,2,4-triazolo /4,3-b-/pyridazin-6-yl)fenyl/alkanamider, karbamater och urreas FI864423A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/793,437 US4654343A (en) 1985-10-31 1985-10-31 N-substituted-N[3-(1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl]alkanamides, carbamates and ureas

Publications (2)

Publication Number Publication Date
FI864423A0 true FI864423A0 (fi) 1986-10-30
FI864423A FI864423A (fi) 1987-05-01

Family

ID=25159919

Family Applications (1)

Application Number Title Priority Date Filing Date
FI864423A FI864423A (fi) 1985-10-31 1986-10-30 N-substituerade-n-/3-(1,2,4-triazolo /4,3-b-/pyridazin-6-yl)fenyl/alkanamider, karbamater och urreas

Country Status (12)

Country Link
US (1) US4654343A (fi)
EP (1) EP0223974A1 (fi)
JP (1) JPS62108882A (fi)
KR (1) KR900004833B1 (fi)
AU (1) AU591940B2 (fi)
DK (1) DK519486A (fi)
ES (1) ES2002430A6 (fi)
FI (1) FI864423A (fi)
HU (1) HU196209B (fi)
NO (1) NO165194C (fi)
NZ (1) NZ218063A (fi)
ZA (1) ZA868280B (fi)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4892873A (en) * 1985-10-31 1990-01-09 American Cyanamid Company N-substituted -N-(3-(1,2,4-triazolo-(4,3-b)pyridazin-6-yl)phenyl)alkanamides, carbamates and ureas
GB9507348D0 (en) * 1995-04-08 1995-05-31 Knoll Ag Therapeutic agents
US20100210590A1 (en) * 1995-09-27 2010-08-19 Northwestern University Compositions and treatments for seizure-related disorders
GB9718254D0 (en) * 1997-08-28 1997-11-05 Merck Sharp & Dohme Therapeutic agents
US6297235B1 (en) * 1997-08-28 2001-10-02 Merck Sharp & Dohme Ltd. Triazolopyridazine derivatives for treating anxiety and enhancing cognition
GB9726701D0 (en) * 1997-12-18 1998-02-18 Merck Sharp & Dohme Therapeutic use
GB9726699D0 (en) * 1997-12-18 1998-02-18 Merck Sharp & Dohme Therapeutic use
GB9723999D0 (en) 1997-11-13 1998-01-14 Merck Sharp & Dohme Therapeutic use
GB9726702D0 (en) * 1997-12-18 1998-02-18 Merck Sharp & Dohme Therapeutic use
US6110915A (en) * 1997-12-18 2000-08-29 Merck & Co., Inc. Antiemetic use of triazolo-pyridazine derivatives
EP1047697A1 (en) 1998-01-14 2000-11-02 MERCK SHARP & DOHME LTD. Triazolo-pyridazine derivatives as ligands for gaba receptors
GB9801208D0 (en) 1998-01-21 1998-03-18 Merck Sharp & Dohme Therapeutic agents
GB9801210D0 (en) 1998-01-21 1998-03-18 Merck Sharp & Dohme Therapeutic agents
SK10922000A3 (sk) * 1998-01-21 2001-03-12 Merck Sharp & Dohme Limited Triazolopyridazínové deriváty, spôsob ich výroby, farmaceutický prostriedok s ich obsahom a ich použitie
GB9801202D0 (en) 1998-01-21 1998-03-18 Merck Sharp & Dohme Therapeutic agents
GB9801234D0 (en) 1998-01-21 1998-03-18 Merck Sharp & Dohme Therapeutic agents
GB9801397D0 (en) 1998-01-22 1998-03-18 Merck Sharp & Dohme Therapeutic agents
GB9801538D0 (en) * 1998-01-23 1998-03-25 Merck Sharp & Dohme Pharmaceutical product
TWI334868B (en) * 2003-06-03 2010-12-21 Nippon Kayaku Kk [1,2,4] triazoro [1,5-a] pyrimidine-2-ylurea derivative and use thereof
KR100658771B1 (ko) * 2004-05-31 2006-12-15 고려대학교 산학협력단 고추 유래의 ＣａＯＤＣ1 유전자 도입 재조합 벡터 및이를 이용하여 형질전환된 식물병 저항성 향상 담배 변종식물체
EP1812007B1 (en) * 2004-11-02 2011-09-07 Northwestern University Pyridazine compounds and methods
ES2543813T3 (es) 2004-11-02 2015-08-24 Northwestern University Compuestos de piridazina para el tratamiento de enfermedades inflamatorias
TW200719895A (en) * 2005-05-26 2007-06-01 Wyeth Corp Method for the treatment of noise phobia in companion animals
US8158627B2 (en) * 2006-04-28 2012-04-17 Northwestern University Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
CA2650625A1 (en) 2006-04-28 2007-11-08 Northwestern University Formulations containing pyridazine compounds for treating neuroinflammatory diseases
EP2015751A2 (en) * 2006-04-28 2009-01-21 Northwestern University Salts of pyridazine compounds
JP2010520223A (ja) * 2007-03-02 2010-06-10 ノースウェスタン ユニバーシティ 発作関連障害のための組成物および方法
EP2170337A4 (en) * 2007-06-28 2013-12-18 Abbvie Inc NEW TRIAZOLOPYRIDAZINE
CA2774715C (en) * 2009-07-27 2018-04-03 Gilead Sciences, Inc. Fused heterocyclic compounds as ion channel modulators
NZ604478A (en) 2010-07-02 2014-12-24 Gilead Sciences Inc Fused heterocyclic compounds as ion channel modulators
EA028156B9 (ru) 2011-05-10 2018-01-31 Джилид Сайэнс, Инк. Конденсированные гетероциклические соединения в качестве модуляторов ионных каналов
TWI478908B (zh) 2011-07-01 2015-04-01 Gilead Sciences Inc 作為離子通道調節劑之稠合雜環化合物
NO3175985T3 (fi) 2011-07-01 2018-04-28
CN112225741B (zh) * 2020-12-09 2021-03-30 中山大学 1,2,4三唑并4,3-b哒嗪衍生物在制备抗炎症因子风暴药物中的应用
WO2024074483A1 (en) * 2022-10-04 2024-04-11 Eth Zurich Compounds for the treatment of myotonic dystrophy

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1080712A (en) * 1976-09-22 1980-07-01 Jay D. Albright Hypotensive agents
US4230705A (en) * 1976-09-22 1980-10-28 American Cyanamid Company 6-Phenyl-1,2,4-triazolo[4,3-b]pyridazines and their uses in treating anxiety
US4112095A (en) * 1976-10-07 1978-09-05 American Cyanamid Company 6-Phenyl-1,2,4-triazolo[4,3-b]pyridazine hypotensive agents
PH12424A (en) * 1976-10-26 1979-02-15 American Cyanamid Co Method of treating anxiety in mammals
US4260755A (en) * 1979-10-31 1981-04-07 American Cyanamid Company Novel 6-phenyl and substituted 6-phenyl-1,2,4-triazolo[4,3-b]pyridazines
DE3217325A1 (de) * 1982-05-08 1983-11-10 Hoechst Ag, 6230 Frankfurt 3-amino-6-aryl-1,2,4-triazolo(4,3-b)-pyridazine, ihre herstellung und ihre verwendung
DE3311753A1 (de) * 1983-03-31 1984-10-04 Hoechst Ag, 6230 Frankfurt Substituierte 6-aryl-1,2,4-triazolo(4,3-b)pyridazine - ihre herstellung und verwendung -

Also Published As

Publication number Publication date
KR900004833B1 (ko) 1990-07-07
DK519486A (da) 1987-05-01
ES2002430A6 (es) 1988-08-01
US4654343A (en) 1987-03-31
DK519486D0 (da) 1986-10-30
NO165194C (no) 1991-01-09
NZ218063A (en) 1990-03-27
AU591940B2 (en) 1989-12-21
NO165194B (no) 1990-10-01
EP0223974A1 (en) 1987-06-03
JPS62108882A (ja) 1987-05-20
KR870004034A (ko) 1987-05-07
AU6454986A (en) 1987-05-07
NO864336L (no) 1987-05-04
NO864336D0 (no) 1986-10-30
FI864423A (fi) 1987-05-01
HU196209B (en) 1988-10-28
ZA868280B (en) 1987-06-24
HUT43609A (en) 1987-11-30

Similar Documents

Publication Publication Date Title
FI864423A0 (fi) N-substituerade-n-/3-(1,2,4-triazolo /4,3-b-/pyridazin-6-yl)fenyl/alkanamider, karbamater och urreas.
FI882742A0 (fi) Vaordande medel och dessa innehaollande kompositioner.
FI870012A0 (fi) Medelst kopplingsreaktion erhaollna fosforhaltiga amider, deras prekursorer och dessa innehaollande smoerjmedelkompositioner.
FI862029A (fi) Askorbinsyraderivat, deras framstaellning och anvaendning.
FI883168A (fi) 6,7-dihydro-pyrazol /1,5-a/ /1,3,5/ triazin-2-sulfonsyraamider, foerfaranden foer deras framstaellning samt deras anvaendning som medel med herbicid och vaexternas tillvaextreglerande effekt.
FI870734A0 (fi) Magnetiskt oevervakningssystem foer foeremaol, foerfarande och kodad markoer.
FI871123A (fi) Pyrazolo/3,4-d/pyrimidinderivat, deras framstaellning och anvaendning.
FI874547A0 (fi) 4,5-dihydro och 4,5,6,7 -tetrahydropyrazolo (1,5-a) pyrimidiner.
FI862691A0 (fi) 2-oxy-4h-3,1-benzoxazin-4-on-derivat och deras foereningar.
FI860556A0 (fi) Nya 1,8-naftyridinderivat och foerfarande foer deras framstaellning.
FI872243A (fi) El- och tryckluftskoppling foer fordon, saosom mellan lastbil och slaepvagn.
FI862642A0 (fi) 3-(substituerade) propenylaminotiazol-yl-kefalosporansyror och deras estrar.
FI860870A0 (fi) Antibakteriska foereningar, deras framstaellning och anvaendning.
FI853787A0 (fi) Elektronisk fjaerrstyrnings- och fjaerrmaetningssystem, speciellt foer foerutsaegning och styrning av foeroreningsaemnen.
FI883315A (fi) 1h-pyrazol-1-alkanamider anvaendbara som antiarrytmiska medel och deras framstaellning.
FI885828A0 (fi) Trometaminsalt av 1-metyl-b-oxo-a -(fenylkarbamoyl)-2-pyrrolpropionitril.
FI860127A (fi) Nya 12-amino-pyridazino/4',5':3,4/ pyrrolo/2,1-a/isokinoliner, foerfarande foer deras framstaellning och anvaendning.
FI862851A (fi) Morfoliniokarboxylsyraester- och morfolinioalkylfenyletersalter, deras framstaellningsfoerfarande och deras anvaendning saosom fungicider.
FI864566A0 (fi) Nitroantracykliner, foerfarande foer deras framstaellning och deras anvaendning.
FI863108A (fi) 3,7-disubstituerade 3-kefemfoereningar och foerfarande foer deras framstaellning.
FI885336A0 (fi) 5,6,7,8-tetrahydro-4h-isoxazolo/4,5/ azepinderivat, deras isomerer och syra-additionssalter.
FI861194A (fi) Substituerade 1,8-naftyridinoner, foerfarande foer deras framstaellning och farmaceutiska blandningar innehaollande dessa.
FI861115A (fi) Imidazo-isokinoliner och imidazo-tienopyridinfoereningar, laekemedel innehaollande dessa foereningar och foerfarande foer deras framstaellning.
FI863794A0 (fi) Alkenylazoler, foerfaranden foer deras framstaellning och deras anvaendning.
FI861884A0 (fi) Foerfaringssaett foer framstaellning av en gjutmassa, innehaollande vattenglas och eventuellt kvarts.

Legal Events

Date Code Title Description
FD Application lapsed

Owner name: AMERICAN CYANAMID COMPANY