FI854528A - Foerfarande och mellanprodukter foer framstaellning av trans-4-substituerade-s-proliner. - Google Patents

Foerfarande och mellanprodukter foer framstaellning av trans-4-substituerade-s-proliner. Download PDF

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Publication number
FI854528A
FI854528A FI854528A FI854528A FI854528A FI 854528 A FI854528 A FI 854528A FI 854528 A FI854528 A FI 854528A FI 854528 A FI854528 A FI 854528A FI 854528 A FI854528 A FI 854528A
Authority
FI
Finland
Prior art keywords
compound
sub
proliner
substituerade
trans
Prior art date
Application number
FI854528A
Other languages
English (en)
Other versions
FI82034C (fi
FI854528A0 (fi
FI82034B (fi
Inventor
John K Thottathil
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of FI854528A0 publication Critical patent/FI854528A0/fi
Publication of FI854528A publication Critical patent/FI854528A/fi
Application granted granted Critical
Publication of FI82034B publication Critical patent/FI82034B/fi
Publication of FI82034C publication Critical patent/FI82034C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI854528A 1984-11-19 1985-11-18 Foerfarande och mellanprodukter foer framstaellning av trans-4-substituerade-s-prolinderivat. FI82034C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67298984 1984-11-19
US06/672,989 US4588819A (en) 1984-11-19 1984-11-19 Process and intermediates for preparing trans-4-substituted-s-prolines

Publications (4)

Publication Number Publication Date
FI854528A0 FI854528A0 (fi) 1985-11-18
FI854528A true FI854528A (fi) 1986-05-20
FI82034B FI82034B (fi) 1990-09-28
FI82034C FI82034C (fi) 1991-01-10

Family

ID=24700865

Family Applications (1)

Application Number Title Priority Date Filing Date
FI854528A FI82034C (fi) 1984-11-19 1985-11-18 Foerfarande och mellanprodukter foer framstaellning av trans-4-substituerade-s-prolinderivat.

Country Status (9)

Country Link
US (1) US4588819A (fi)
EP (1) EP0183390B1 (fi)
JP (3) JPH0637461B2 (fi)
AT (1) ATE49751T1 (fi)
CA (3) CA1265525C (fi)
DE (1) DE3575555D1 (fi)
FI (1) FI82034C (fi)
HU (1) HU196056B (fi)
IE (1) IE58763B1 (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4734508A (en) * 1987-05-01 1988-03-29 E. R. Squibb & Sons, Inc. Process and intermediates for preparing 4-substituted proline derivatives
US4851514A (en) * 1987-05-01 1989-07-25 E. R. Squibb & Sons, Inc. Process for preparing a compound useful in preparing ace inhibitors and intermediate produced thereby
CA1333807C (en) * 1987-06-15 1995-01-03 David R. Kronenthal Process for preparing (trans)-4-phenyl-l-proline derivatives
US4912231A (en) * 1987-06-15 1990-03-27 E. R. Squibb & Sons, Inc. Process for preparing (trans)-4-phenyl-L-proline derivatives
US4937355A (en) * 1989-01-17 1990-06-26 E. R. Squibb & Sons, Inc. Process for preparing (trans)-4-substituted-dl-proline derivatives
CN101462996B (zh) * 2007-12-21 2011-04-20 上海医药工业研究院 4-环己基脯氨酸衍生物的制备方法
CN101445475B (zh) * 2008-12-30 2010-12-22 浙江工业大学 一种(反)-4-环己基-l-脯氨酸的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1199273B (de) * 1959-06-22 1965-08-26 Mead Johnson & Co Verfahren zur Herstellung von 3-Oxymethyl-pyrrolidinen
CH435287A (de) * 1964-02-11 1967-05-15 Geigy Ag J R Verfahren zur Herstellung von neuen, kondensierten heterocyclischen Verbindungen
US3544590A (en) * 1967-04-28 1970-12-01 Exxon Research Engineering Co Cyclic amines and the process for their formation
US3636043A (en) * 1969-02-04 1972-01-18 Upjohn Co Method for the preparation of 4-alkylprolines and compounds produced thereby
JPS5821622B2 (ja) * 1973-02-28 1983-05-02 ウェルファイド株式会社 ピロリジンメタノ−ル ノ セイゾウホウ
US4105776A (en) * 1976-06-21 1978-08-08 E. R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4168267A (en) * 1978-10-23 1979-09-18 E. R. Squibb & Sons, Inc. Phosphinylalkanoyl prolines
US4337201A (en) * 1980-12-04 1982-06-29 E. R. Squibb & Sons, Inc. Phosphinylalkanoyl substituted prolines
FR2520360A1 (fr) * 1982-01-26 1983-07-29 Nicoud Jean Nouveaux derives de la paranitroaniline utilisables en optique non lineaire et en electro-optique et leur procede de preparation
DE3306199A1 (de) * 1983-02-23 1984-08-23 Bayer Ag, 5090 Leverkusen 7-oxo-3-oxa-1-azabicyclo(3.2.0)heptan-2-carbonsaeuren und deren derivate

Also Published As

Publication number Publication date
IE58763B1 (en) 1993-11-03
JPH0637461B2 (ja) 1994-05-18
CA1278298C (en) 1990-12-27
EP0183390B1 (en) 1990-01-24
FI82034C (fi) 1991-01-10
JPH0747591B2 (ja) 1995-05-24
HUT40408A (en) 1986-12-28
CA1265525A (en) 1990-02-06
JPH0723357B2 (ja) 1995-03-15
ATE49751T1 (de) 1990-02-15
DE3575555D1 (de) 1990-03-01
JPH06293731A (ja) 1994-10-21
FI854528A0 (fi) 1985-11-18
CA1265525C (en) 1990-02-06
HU196056B (en) 1988-09-28
JPH06293773A (ja) 1994-10-21
CA1278296C (en) 1990-12-27
IE852729L (en) 1986-05-19
US4588819A (en) 1986-05-13
EP0183390A1 (en) 1986-06-04
JPS61122264A (ja) 1986-06-10
FI82034B (fi) 1990-09-28

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Legal Events

Date Code Title Description
FG Patent granted

Owner name: E.R. SQUIBB & SONS, INC.

MA Patent expired