FI853174A0 - Bicykliska foereningar. - Google Patents

Bicykliska foereningar.

Info

Publication number
FI853174A0
FI853174A0 FI853174A FI853174A FI853174A0 FI 853174 A0 FI853174 A0 FI 853174A0 FI 853174 A FI853174 A FI 853174A FI 853174 A FI853174 A FI 853174A FI 853174 A0 FI853174 A0 FI 853174A0
Authority
FI
Finland
Prior art keywords
foereningar
bicycle
bicycle foereningar
Prior art date
Application number
FI853174A
Other languages
English (en)
Other versions
FI853174L (fi
Inventor
Cedric Herbert Hassall
Geoffrey Lawton
Sally Redshaw
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848421493A external-priority patent/GB8421493D0/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI853174A0 publication Critical patent/FI853174A0/fi
Publication of FI853174L publication Critical patent/FI853174L/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
FI853174A 1984-08-24 1985-08-19 Bicykliska foereningar. FI853174L (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848421493A GB8421493D0 (en) 1984-08-24 1984-08-24 Bicyclic compounds
GB858513541A GB8513541D0 (en) 1984-08-24 1985-05-29 Bicyclic compounds

Publications (2)

Publication Number Publication Date
FI853174A0 true FI853174A0 (fi) 1985-08-19
FI853174L FI853174L (fi) 1986-02-25

Family

ID=26288155

Family Applications (1)

Application Number Title Priority Date Filing Date
FI853174A FI853174L (fi) 1984-08-24 1985-08-19 Bicykliska foereningar.

Country Status (14)

Country Link
US (4) US4692438A (fi)
EP (1) EP0172552A3 (fi)
AU (1) AU583843B2 (fi)
CS (1) CS255893B2 (fi)
DK (1) DK384385A (fi)
ES (3) ES8700258A1 (fi)
FI (1) FI853174L (fi)
HU (1) HU193446B (fi)
IL (1) IL76133A (fi)
MC (1) MC1694A1 (fi)
NO (1) NO161914C (fi)
NZ (1) NZ213130A (fi)
PH (1) PH21749A (fi)
PT (1) PT81015B (fi)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4692438A (en) * 1984-08-24 1987-09-08 Hoffmann-La Roche Inc. Pyridazo-diazepines, diazocines, and -triazepines having anti-hypertensive activity
ZW11586A1 (en) * 1985-07-01 1987-12-30 Hoffmann La Roche Bicyclic compounds
GB8629875D0 (en) * 1986-12-15 1987-01-28 Hoffmann La Roche Pyridazodiazepine derivatives
US5430145A (en) * 1990-10-18 1995-07-04 Merrell Dow Pharmaceuticals Inc. Mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace
US5308841A (en) * 1990-12-21 1994-05-03 Merrell Dow Pharmaceuticals Inc. Amino and nitro containing tricyclic compounds useful as inhibitors of ACE
US5457196A (en) * 1991-09-27 1995-10-10 Merrell Dow Pharmaceuticals Inc. 2-substituted indane-2-carboxyalkyl derivatives useful as inhibitors of enkephalinase and ACE
US5455242A (en) * 1991-09-27 1995-10-03 Merrell Dow Pharmaceuticals Inc. Carboxyalkyl tricyclic derivatives useful as inhibitors of enkephalinase and ace
DE69220744T2 (de) * 1991-09-27 1997-11-13 Merrell Pharma Inc 2-Substituierte Indan-2-Mercaptoacetylamid-Verbindungen mit Enkephalinase und ACE-Hemmwirkung
EP0625987B1 (en) * 1992-02-14 1998-04-01 Merrell Pharmaceuticals Inc. Aminoacetylmercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace
KR100281450B1 (ko) * 1992-05-15 2001-02-01 슈테펜 엘. 네스비트 엔케팔리나제 및 안지오텐신 전환 효소의 억제제로서 유용한 신규 메르캅토아세틸아미도 피리다조[1,2]피리다진, 피라졸로[1,2]피리다진, 피리다조[1,2-a][1,2]디아제핀 및 피라졸로[1,2-a][1,2]디아제핀 유도체
US5420271A (en) * 1992-08-24 1995-05-30 Merrell Dow Pharmaceuticals, Inc. 2-substituted indane-2-mercaptoacetylamide tricyclic derivatives useful as inhibitors of enkephalinase
DK0669936T3 (da) * 1992-10-30 2001-02-05 Merrell Pharma Inc Mercaptoacetylamidsubstitueret bicyklisk lactam til anvendelse som enkephalinase- og ACE-inhibitorer
WO1994022440A1 (en) * 1993-03-29 1994-10-13 Smithkline Beecham Corporation Bicyclic compounds which inhibit platelet aggregation
US5530013A (en) * 1994-02-14 1996-06-25 American Home Products Corporation Venlafaxine in the inducement of cognition enhancement
HUT74385A (en) * 1994-02-14 1996-12-30 Merrell Pharma Inc Novel mercaptoacetylamido 1,3,4,5-tetrahydro-benzo[c]azepin-3-one disulfide derivatives useful as inhibitors of enkephalinase and ace
DE69524064T2 (de) * 1994-02-14 2002-07-11 Merrell Pharma Inc Indan-2-mercaptoacetylamid disulfidderivate als enkephalinase inhibitoren
WO1995021839A1 (en) * 1994-02-14 1995-08-17 Merrell Pharmaceuticals Inc. Novel mercaptoacetylamide disulfide derivatives useful as inhibitors of enkephalinase and ace
JP3561753B2 (ja) * 1994-02-14 2004-09-02 メレル ファーマスーティカルズ インコーポレーテッド エンケファリナーゼ及びａｃｅの阻害剤として有用な、新規な２−置換インダン−２−メルカプトアセチルアミドジスルフィド誘導体類
US5484783A (en) * 1994-03-24 1996-01-16 Merrell Dow Pharmaceuticals Inc. Hypocholesterolemic, antiatherosclerotic and hypotriglyceridemic mercaptoacetylamide and benzazapine derivatives
NZ282565A (en) * 1994-03-24 1999-11-29 Merrell Pharma Inc Condensed mercaptoacetylamidedisulphidebenzazepines used in treating elevated cholesterol levels, atherosclerosis, and hypotriglyceridemia
DK0751783T3 (da) * 1994-03-24 2000-06-26 Merrell Pharma Inc Hypokolesterolæmisk, antiatherosklerotisk og hypotriglyceridæmisk anvendelse af aminoacetylmercaptoderivater
US6703500B2 (en) 1998-08-19 2004-03-09 Vertex Pharmaceuticals, Incorporated Method of preparing bicyclic intermediates from piperazic acid or an ester thereof useful in the manufacture of caspase inhibitors
US6559304B1 (en) * 1998-08-19 2003-05-06 Vertex Pharmaceuticals Incorporated Method for synthesizing caspase inhibitors
US6177565B1 (en) * 1998-08-19 2001-01-23 Vertex Pharmaceuticals Inc. Process for synthesizing piperazic acid
WO2001083458A2 (en) * 2000-05-04 2001-11-08 Vertex Pharmaceuticals Incorporated Asymmetric synthesis of piperazic acid and derivatives thereof
GB0119305D0 (en) 2001-04-12 2001-10-03 Aventis Pharma Gmbh Mercaptoacetylamide derivatives,a process for their preparation and their use
WO2010010427A1 (en) * 2008-07-25 2010-01-28 Chuluun Enkhbold A method of solid fuel beneficiation and transportation to thermoelectric power stations
CN102686594A (zh) 2009-12-16 2012-09-19 熙德隆研究基金会 地瑞那韦的多晶型物
EP2571355B1 (en) 2010-05-20 2016-09-07 Hetero Research Foundation Crystalline hydrochloride salt of darunavir

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4308094A (en) * 1977-02-02 1981-12-29 Sanyo Electric Co., Ltd. Diaphragm for speaker and method of producing same
IL60617A0 (en) * 1979-07-23 1980-09-16 Sparamedica Ag Triazolopyridazine derivative,their preparation and pharmaceutical compositions containing them
EP0025941B1 (de) * 1979-09-19 1983-05-04 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Pyridazopyridazinderivate, Verfahren zu deren Herstellung und Arzneimittel enthaltend solche Pyridazopyridazinderivate
EP0042100A1 (de) * 1980-06-13 1981-12-23 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Pyrazolopyridazin-Derivate, Zwischenprodukte und Verfahren zu deren Herstellung, sowie diese enthaltende Arzneimittel
GB2128984B (en) * 1982-05-12 1985-05-22 Hoffmann La Roche Diaza-bicyclic compounds
US4692438A (en) * 1984-08-24 1987-09-08 Hoffmann-La Roche Inc. Pyridazo-diazepines, diazocines, and -triazepines having anti-hypertensive activity

Also Published As

Publication number Publication date
DK384385D0 (da) 1985-08-23
US4692438A (en) 1987-09-08
ES552398A0 (es) 1987-05-01
PT81015B (en) 1987-08-24
HU193446B (en) 1987-10-28
US4785093A (en) 1988-11-15
ES8705444A1 (es) 1987-05-01
CS592885A2 (en) 1987-07-16
ES8700258A1 (es) 1986-10-01
US4826980A (en) 1989-05-02
ES8705443A1 (es) 1987-05-01
HUT38644A (en) 1986-06-30
EP0172552A3 (de) 1989-01-11
FI853174L (fi) 1986-02-25
PT81015A (en) 1985-09-01
NO853336L (no) 1986-02-25
AU4641585A (en) 1986-02-27
DK384385A (da) 1986-02-25
MC1694A1 (fr) 1986-07-18
AU583843B2 (en) 1989-05-11
EP0172552A2 (de) 1986-02-26
IL76133A0 (en) 1985-12-31
US4762924A (en) 1988-08-09
ES546360A0 (es) 1986-10-01
NO161914C (no) 1989-10-11
PH21749A (en) 1988-02-18
IL76133A (en) 1989-12-15
CS255893B2 (en) 1988-03-15
ES552397A0 (es) 1987-05-01
NZ213130A (en) 1988-05-30
NO161914B (no) 1989-07-03

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: F. HOFFMANN-LA ROCHE AG