FI851120L - Cyklosporin, dess framstaellning och anvaendning. - Google Patents

Cyklosporin, dess framstaellning och anvaendning.

Info

Publication number
FI851120L
FI851120L FI851120A FI851120A FI851120L FI 851120 L FI851120 L FI 851120L FI 851120 A FI851120 A FI 851120A FI 851120 A FI851120 A FI 851120A FI 851120 L FI851120 L FI 851120L
Authority
FI
Finland
Prior art keywords
cyclosporin
framstaellning och
dess framstaellning
och anvaendning
anvaendning
Prior art date
Application number
FI851120A
Other languages
English (en)
Finnish (fi)
Other versions
FI851120A7 (fi
FI851120A0 (fi
Inventor
Roland Wenger
Rene P Traber
Hans Kobel
Hans Hofmann
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848407618A external-priority patent/GB8407618D0/en
Priority claimed from GB848411922A external-priority patent/GB8411922D0/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of FI851120A0 publication Critical patent/FI851120A0/fi
Publication of FI851120A7 publication Critical patent/FI851120A7/fi
Publication of FI851120L publication Critical patent/FI851120L/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/19—Antibiotic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Transplantation (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI851120A 1984-03-23 1985-03-20 Cyklosporin, dess framstaellning och anvaendning. FI851120L (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848407618A GB8407618D0 (en) 1984-03-23 1984-03-23 Organic compounds
GB848411922A GB8411922D0 (en) 1984-05-10 1984-05-10 Organic compounds

Publications (3)

Publication Number Publication Date
FI851120A0 FI851120A0 (fi) 1985-03-20
FI851120A7 FI851120A7 (fi) 1985-09-24
FI851120L true FI851120L (fi) 1985-09-24

Family

ID=26287502

Family Applications (1)

Application Number Title Priority Date Filing Date
FI851120A FI851120L (fi) 1984-03-23 1985-03-20 Cyklosporin, dess framstaellning och anvaendning.

Country Status (24)

Country Link
US (1) US4639434A (enFirst)
JP (1) JPH08838B2 (enFirst)
AT (1) AT388737B (enFirst)
BE (1) BE901980A (enFirst)
CA (1) CA1247546A (enFirst)
CH (1) CH667274A5 (enFirst)
CS (1) CS249542B2 (enFirst)
DE (1) DE3509809A1 (enFirst)
DK (1) DK128285A (enFirst)
ES (1) ES8702926A1 (enFirst)
FI (1) FI851120L (enFirst)
FR (1) FR2561651B1 (enFirst)
GB (1) GB2155936B (enFirst)
GR (1) GR850716B (enFirst)
HU (1) HU200786B (enFirst)
IL (1) IL74681A (enFirst)
IT (1) IT1199962B (enFirst)
LU (1) LU85819A1 (enFirst)
NL (1) NL8500828A (enFirst)
NO (1) NO851160L (enFirst)
NZ (1) NZ211526A (enFirst)
PH (2) PH21868A (enFirst)
PT (1) PT80149B (enFirst)
SE (1) SE461334B (enFirst)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE92501T1 (de) 1984-10-04 1993-08-15 Sandoz Ag Monoklonale antikoerper gegen zyklosporine.
US4798823A (en) * 1987-06-03 1989-01-17 Merck & Co., Inc. New cyclosporin analogs with modified "C-9 amino acids"
ATE95193T1 (de) * 1987-06-17 1993-10-15 Sandoz Ag Cyclosporine und deren benutzung als arzneimittel.
DE3888357T2 (de) * 1987-06-22 1994-09-15 Merck & Co Inc Cyclosporin-Derivate, die eine modifizierte Aminosäure auf Stellung 8 tragen.
US5227467A (en) * 1987-08-03 1993-07-13 Merck & Co., Inc. Immunosuppressive fluorinated cyclosporin analogs
WO1989001772A1 (en) * 1987-09-03 1989-03-09 University Of Georgia Research Foundation, Inc. Ocular cyclosporin composition
US4839342A (en) * 1987-09-03 1989-06-13 University Of Georgia Research Foundation, Inc. Method of increasing tear production by topical administration of cyclosporin
US5089390A (en) * 1987-09-04 1992-02-18 Syntex (U.S.A.) Inc. 2-methyl-4-hexene- and 2-methyl-4-heptene-1,2-diol derivatives
US5236899A (en) * 1987-11-16 1993-08-17 Merck & Co., Inc. 6-position cyclosporin a analogs as modifiers of cytotoxic drug resistance
US4914188A (en) * 1987-11-16 1990-04-03 Merck & Co., Inc. Novel 6-position cyclosporin analogs as non-immunosuppressive antagonists of cyclosporin binding to cyclophilin
CH679119A5 (enFirst) * 1988-05-13 1991-12-31 Sandoz Ag
US5540931A (en) * 1989-03-03 1996-07-30 Charles W. Hewitt Methods for inducing site-specific immunosuppression and compositions of site specific immunosuppressants
US4996193A (en) * 1989-03-03 1991-02-26 The Regents Of The University Of California Combined topical and systemic method of administration of cyclosporine
GB8916901D0 (en) 1989-07-24 1989-09-06 Sandoz Ltd Improvements in or relating to organic compounds
US5122511A (en) * 1990-02-27 1992-06-16 Merck & Co., Inc. Immunosuppressive cyclosporin analogs with modified amino acids at position-8
US5202310A (en) * 1990-06-06 1993-04-13 Levy Gary A Cyclosporine metabolites
FI111730B (fi) 1990-11-02 2003-09-15 Novartis Ag Menetelmä ei-immunosuppressiivisen syklosporiinin valmistamiseksi
CA2055813A1 (en) * 1990-11-20 1992-05-21 Dariush Davalian Cyclosporin immunoassay
US5747330A (en) * 1996-06-05 1998-05-05 Poli Industria Chimica Antibiotic producing microbe
RU2170741C2 (ru) * 1996-08-16 2001-07-20 Новартис Аг Способ получения циклоспорина
US20030220234A1 (en) * 1998-11-02 2003-11-27 Selvaraj Naicker Deuterated cyclosporine analogs and their use as immunodulating agents
DE69832984T2 (de) 1997-10-08 2006-09-21 Isotechnika, Inc., Edmonton DEUTERIERtE und undeuterierte CYCLOSPORIN-ANALOGA UND IHRE VERWENDUNG ALS IMMUNMODULIERENDE AGENtIEN
US5990274A (en) 1997-11-25 1999-11-23 Dade Behring Inc. Cyclosporine derivatives and uses thereof
US7449544B2 (en) * 1999-11-30 2008-11-11 Cyclacel Limited p21 peptides
HRP20070058B1 (hr) 2001-10-19 2014-05-23 Isotechnika Inc. Sinteza ciklosporinskih analoga
EP1435910B9 (en) * 2001-10-19 2010-02-03 Isotechnika Inc. Novel cyclosporin analog microemulsion preconcentrates
CA2518265A1 (en) * 2003-03-17 2004-09-30 Albany Molecular Research, Inc. Novel cyclosporins
JP2008514702A (ja) * 2004-09-29 2008-05-08 エーエムアール テクノロジー インコーポレイテッド 新規シクロスポリン類似体およびそれらの薬学的使用
US7378391B2 (en) * 2004-09-29 2008-05-27 Amr Technology, Inc. Cyclosporin alkyne analogues and their pharmaceutical uses
WO2006041631A2 (en) * 2004-10-06 2006-04-20 Amr Technology, Inc. Novel cyclosporin alkynes and their utility as pharmaceutical agents
US7696165B2 (en) * 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
US7696166B2 (en) * 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders
WO2008069917A2 (en) 2006-11-20 2008-06-12 Scynexis, Inc. Novel cyclic peptides
AU2011342284C1 (en) 2010-12-15 2017-07-13 Contravir Pharmaceuticals, Inc. Cyclosporine analogue molecules modified at amino acid 1 and 3
HUE065915T2 (hu) 2011-03-11 2024-06-28 Beth Israel Deaconess Medical Ct Inc Anti-CD40 antitestek és alkalmazásaik
CN104877013B (zh) * 2015-06-03 2018-04-20 兰州大学 环孢菌素t及其制备方法和应用
WO2017040932A1 (en) 2015-09-04 2017-03-09 Primatope Therapeutics Inc. Humanized anti-cd40 antibodies and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57140753A (en) * 1981-01-09 1982-08-31 Sandoz Ag Novel cyclosporine
DE3260468D1 (en) * 1981-01-09 1984-09-06 Sandoz Ag Novel cyclosporins

Also Published As

Publication number Publication date
ATA86385A (de) 1989-01-15
CA1247546A (en) 1988-12-28
GB8507270D0 (en) 1985-04-24
GB2155936A (en) 1985-10-02
DK128285D0 (da) 1985-03-21
PH21868A (en) 1988-03-25
IT8547852A0 (it) 1985-03-22
IL74681A0 (en) 1985-06-30
GR850716B (enFirst) 1985-07-19
PT80149B (en) 1987-03-23
CS249542B2 (en) 1987-03-12
FR2561651A1 (fr) 1985-09-27
SE461334B (sv) 1990-02-05
HU200786B (en) 1990-08-28
CH667274A5 (de) 1988-09-30
ES541465A0 (es) 1987-01-16
BE901980A (fr) 1985-09-23
NZ211526A (en) 1988-08-30
PH23357A (en) 1989-07-14
DK128285A (da) 1985-09-24
HUT38370A (en) 1986-05-28
NO851160L (no) 1985-09-24
FI851120A7 (fi) 1985-09-24
IT1199962B (it) 1989-01-05
ES8702926A1 (es) 1987-01-16
US4639434A (en) 1987-01-27
SE8501392L (sv) 1985-09-24
PT80149A (en) 1985-04-01
NL8500828A (nl) 1985-10-16
JPH08838B2 (ja) 1996-01-10
FR2561651B1 (fr) 1990-03-09
DE3509809A1 (de) 1986-01-09
GB2155936B (en) 1987-09-16
LU85819A1 (fr) 1985-12-12
JPS60215700A (ja) 1985-10-29
SE8501392D0 (sv) 1985-03-21
FI851120A0 (fi) 1985-03-20
IT8547852A1 (it) 1986-09-22
IL74681A (en) 1989-09-10
AT388737B (de) 1989-08-25

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: SANDOZ AG