FI845116A0 - 4h-3,1-benzoxazin-4-oner och motsvarande foereningar. - Google Patents
4h-3,1-benzoxazin-4-oner och motsvarande foereningar.Info
- Publication number
- FI845116A0 FI845116A0 FI845116A FI845116A FI845116A0 FI 845116 A0 FI845116 A0 FI 845116A0 FI 845116 A FI845116 A FI 845116A FI 845116 A FI845116 A FI 845116A FI 845116 A0 FI845116 A0 FI 845116A0
- Authority
- FI
- Finland
- Prior art keywords
- foereningar
- oner
- benzoxazin
- och
- motor variable
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/18—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C265/00—Derivatives of isocyanic acid
- C07C265/16—Derivatives of isocyanic acid having isocyanate groups acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
- C07C273/1809—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety
- C07C273/1818—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety from -N=C=O and XNR'R"
- C07C273/1827—X being H
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C07K5/06043—Leu-amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
- C07K5/0823—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Pro-amino acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56612983A | 1983-12-27 | 1983-12-27 | |
| US56612983 | 1983-12-27 | ||
| US60860984A | 1984-05-09 | 1984-05-09 | |
| US60860984 | 1984-05-09 | ||
| US06/673,996 US4657893A (en) | 1984-05-09 | 1984-11-26 | 4H-3,1-benzoxazin-4-ones and related compounds and use as enzyme inhibitors |
| US67399684 | 1984-11-26 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI845116A0 true FI845116A0 (fi) | 1984-12-27 |
| FI845116L FI845116L (fi) | 1985-06-28 |
| FI79842B FI79842B (fi) | 1989-11-30 |
| FI79842C FI79842C (fi) | 1990-03-12 |
Family
ID=27415984
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI845116A FI79842C (fi) | 1983-12-27 | 1984-12-27 | Foerfarande foer framstaellning av terapeutiskt verksamma 4h-3,1-bensoxazin-4-onderivat. |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0147211B1 (fi) |
| KR (1) | KR890000992B1 (fi) |
| CA (1) | CA1269800A (fi) |
| DE (1) | DE3483204D1 (fi) |
| DK (1) | DK625184A (fi) |
| ES (2) | ES8607260A1 (fi) |
| FI (1) | FI79842C (fi) |
| HU (1) | HU195648B (fi) |
| IL (1) | IL73943A (fi) |
| NO (1) | NO163184C (fi) |
| NZ (1) | NZ210669A (fi) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1309556C (en) * | 1987-06-09 | 1992-10-27 | Masayuki Kokubo | 4h-3,1-benzoxazin-4-one compounds and pharmaceutical composition thereoffor the inhibition of serine proteases |
| EP0475531B1 (en) * | 1990-09-10 | 1995-01-18 | Asahi Kasei Kogyo Kabushiki Kaisha | Benzoic acid phenylester compounds and elastase inhibiting compositions containing the same |
| US5652237A (en) * | 1994-09-09 | 1997-07-29 | Warner-Lambert Company | 2-substituted-4H-3, 1-benzoxazin-4-ones and benzthiazin-4-ones as inhibitors of complement C1r protease for the treatment of inflammatory processes |
| US5985872A (en) * | 1995-05-24 | 1999-11-16 | G.D. Searle & Co. | 2-amino-benzoxazinones for the treatment of viral infections |
| GB9700597D0 (en) * | 1997-01-14 | 1997-03-05 | Sandoz Pharma Uk | Organic compounds |
| US6180625B1 (en) | 1998-03-24 | 2001-01-30 | Novo Nordisk A/S | Heterocyclic compounds regulating clotting |
| WO1999048878A1 (en) * | 1998-03-24 | 1999-09-30 | Novo Nordisk A/S | Heterocyclic compounds regulating clotting |
| AU1375000A (en) * | 1998-11-26 | 2000-06-13 | Novo Nordisk A/S | Heterocyclic compounds regulating clotting |
| GB9900416D0 (en) * | 1999-01-08 | 1999-02-24 | Alizyme Therapeutics Ltd | Inhibitors |
| CA2359112A1 (en) | 1999-01-22 | 2000-07-27 | Elan Pharmaceuticals, Inc. | Fused ring heteroaryl and heterocyclic compounds which inhibit leukocyte adhesion mediated by vla-4 |
| JP2002535314A (ja) | 1999-01-22 | 2002-10-22 | エラン ファーマシューティカルズ，インコーポレイテッド | Ｖｌａ−４により媒介される白血球接着を阻害する化合物 |
| US6436904B1 (en) | 1999-01-25 | 2002-08-20 | Elan Pharmaceuticals, Inc. | Compounds which inhibit leukocyte adhesion mediated by VLA-4 |
| TWI281470B (en) | 2002-05-24 | 2007-05-21 | Elan Pharm Inc | Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha4 integrins |
| TW200307671A (en) | 2002-05-24 | 2003-12-16 | Elan Pharm Inc | Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins |
| NZ567270A (en) | 2005-09-29 | 2011-06-30 | Elan Pharm Inc | Pyrimidinyl amide compounds which inhibit leukocyte adhesion mediated by VLA-4 |
| CN101273035A (zh) | 2005-09-29 | 2008-09-24 | 伊兰制药公司 | 抑制由vla-4介导的白细胞粘附的氨基甲酸酯化合物 |
| EA017110B1 (ru) | 2006-02-27 | 2012-09-28 | Элан Фамэсьютикэлс, Инк. | ПИРИМИДИНИЛСУЛЬФОНАМИДНЫЕ СОЕДИНЕНИЯ (ВАРИАНТЫ), СПОСОБ ПОЛУЧЕНИЯ ПИРИМИДИНИЛСУЛЬФОНАМИДНЫХ СОЕДИНЕНИЙ (ВАРИАНТЫ), ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, СПОСОБ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЯ, ОПОСРЕДОВАННОГО ИНТЕГРИНОМ α4, СПОСОБ СНИЖЕНИЯ И/ИЛИ ПРЕДУПРЕЖДЕНИЯ ВОСПАЛИТЕЛЬНОГО КОМПОНЕНТА ЗАБОЛЕВАНИЯ ИЛИ АУТОИММУННОГО ОТВЕТА |
| MX2011011326A (es) | 2009-04-27 | 2012-02-13 | Elan Pharm Inc | Antagonistas de piridinona de las integrinas alfa-4. |
| EP3565543A4 (en) * | 2017-01-06 | 2020-10-14 | The Regents of The University of California | MU TYPE OPIOID RECEIVER MODULATORS |
| AU2019247842B2 (en) | 2018-04-04 | 2023-08-31 | Epiodyne, Inc. | Opioid receptor modulators and products and methods related thereto |
| TW202304869A (zh) | 2021-04-05 | 2023-02-01 | 美商艾碧奧戴股份有限公司 | 類鴉片受體調節劑 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3450700A (en) * | 1966-12-20 | 1969-06-17 | Upjohn Co | 2-tertiary amino-4h-3,1-benzoxazin-4-ones |
| DE2315303A1 (de) * | 1973-03-27 | 1974-10-17 | Bayer Ag | Verfahren zur herstellung von n-substituierten 2-amino-3,1-benzoxazin-4-onen |
-
1984
- 1984-12-20 NZ NZ210669A patent/NZ210669A/en unknown
- 1984-12-21 DE DE8484309013T patent/DE3483204D1/de not_active Expired - Fee Related
- 1984-12-21 EP EP84309013A patent/EP0147211B1/en not_active Expired - Lifetime
- 1984-12-21 CA CA000470962A patent/CA1269800A/en not_active Expired - Fee Related
- 1984-12-21 NO NO845176A patent/NO163184C/no unknown
- 1984-12-21 DK DK625184A patent/DK625184A/da not_active Application Discontinuation
- 1984-12-26 KR KR1019840008352A patent/KR890000992B1/ko not_active IP Right Cessation
- 1984-12-26 IL IL73943A patent/IL73943A/xx unknown
- 1984-12-26 ES ES539038A patent/ES8607260A1/es not_active Expired
- 1984-12-27 FI FI845116A patent/FI79842C/fi not_active IP Right Cessation
- 1984-12-27 HU HU844839A patent/HU195648B/hu not_active IP Right Cessation
-
1986
- 1986-01-14 ES ES550879A patent/ES8703437A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NO845176L (no) | 1985-06-28 |
| ES550879A0 (es) | 1987-03-01 |
| HU195648B (en) | 1988-06-28 |
| IL73943A0 (en) | 1985-03-31 |
| DK625184A (da) | 1985-06-28 |
| ES8703437A1 (es) | 1987-03-01 |
| DE3483204D1 (de) | 1990-10-18 |
| DK625184D0 (da) | 1984-12-21 |
| ES8607260A1 (es) | 1986-06-01 |
| EP0147211B1 (en) | 1990-09-12 |
| FI845116L (fi) | 1985-06-28 |
| CA1269800A (en) | 1990-05-29 |
| FI79842C (fi) | 1990-03-12 |
| EP0147211A2 (en) | 1985-07-03 |
| IL73943A (en) | 1989-01-31 |
| KR850004472A (ko) | 1985-07-15 |
| EP0147211A3 (en) | 1985-08-14 |
| NO163184C (no) | 1990-04-18 |
| HUT36808A (en) | 1985-10-28 |
| NZ210669A (en) | 1988-05-30 |
| ES539038A0 (es) | 1986-06-01 |
| FI79842B (fi) | 1989-11-30 |
| KR890000992B1 (ko) | 1989-04-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI843594L (fi) | Trihalogenmetylgrupper innehaollande karbonylmetylenheterocykler, foerfarande foer deras framstaellning och ljuskaenslig blandning vilken innehaoller dessa foereningar. | |
| FI77939B (fi) | Askorbatstoerningsfri komposition, anordning och foerfarande foer bestaemning av peroxidativt aktiva substanser. | |
| FI843403A (fi) | Blandarmatur foer blandning av tvao vaetskor, saerskilt kallt och varmt vatten. | |
| FI845038L (fi) | Vattenloeslig, aminerad -1,3-bunden d-glukan och komposition innehaollande densamma. | |
| FI845116L (fi) | 4h-3,1-benzoxazin-4-oner och motsvarande foereningar. | |
| FI843856A0 (fi) | 1-benzyl-aminoalkyl-pyrrolidinoner och deras syraadditionssalter, foerfarande foer deras framstaellning och laekemedel. | |
| FI841128A0 (fi) | Pyrimidinderivat, deras framstaellning och deras anvaendning. | |
| FI842459A (fi) | Tetrahydropyridazinonderivat, foerfaranden foer deras framstaellning och deras anvaendning. | |
| FI843342A0 (fi) | Anordning foer traening av benmuskulatur, cirkulation och armmuskulatur. | |
| FI841841A0 (fi) | 1-pyrimidinyloxi-3-hetarylalkylamino-2- propanoler, deras framstaellning och anvaendning. | |
| FI844889A0 (fi) | Foernaetade polymerater, foerfarande foer deras framstaellning och deras anvaendning. | |
| FI840206A (fi) | Aminosyraderivat, foerfarande foer deras framstaellning och anvaendning. | |
| FI830032L (fi) | Foerfarande och anordning foer bestaemmande av en oenskad centrallinje foer cylinderlika kroppar, saosom traestockar. | |
| FI840428A (fi) | Biologiskt aktivt ketonderivat, framstaellning och anvaendning. | |
| FI842210A (fi) | Kefalosporinester-derivat, deras framstaellning och anvaendning. | |
| FI841479A (fi) | Fenylalaninhydroxilas- cdna- kloner, foerfarande foer framstaellning av dessa och anvaendning av dessa foer diagnostisering av fenylketonuri. | |
| FI841615A0 (fi) | 4-fenyl-tetrahydro-furano-pyridiner, foerfarande foer deras framstaellning och farmaceutiska blandningar. | |
| FI843825L (fi) | Faergkatodstraolroer, komponent och framstaellningsmetod. | |
| FI844002L (fi) | Stabiliserade, inerta organiska vaetskor innehaollande natriumditionitprodukter och deras anvaendning. | |
| FI840843A (fi) | Plasmider, foerfarande foer framstaellning av dessa, mikroorganismer innehaollande dessa och foerfaranden foer odling av mikroorganismerna. | |
| FI843824L (fi) | Faergkatodstraolroer, komponent och framstaellningsmetod. | |
| FI842300A0 (fi) | Mono- och ditioestrar, deras framstaellning och anvaendning. | |
| FI843973A0 (fi) | Foerfarande foer oeverfoering, saerskilt foer registrering och aotergivning av faergtelevisionssignaler. | |
| FI844884L (fi) | Akryltelomerer innehaollande medelst ljus tvaerbindande sidokedjor, syntes daerav och anvaendning av dessa foer belaeggning av metaller. | |
| FI840587A (fi) | Mjoeldryga-alkaloider, deras framstaellning och anvaendning. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed |
Owner name: SYNTEX (U.S.A.) INC. |