FI823165A0 - -laktamas inhibiterande 2- -substituerade-2- metyl(5r) penam-3- -karboxylsyra-1,1-dioxider och deras mellanprodukter - Google Patents

-laktamas inhibiterande 2- -substituerade-2- metyl(5r) penam-3- -karboxylsyra-1,1-dioxider och deras mellanprodukter

Info

Publication number
FI823165A0
FI823165A0 FI823165A FI823165A FI823165A0 FI 823165 A0 FI823165 A0 FI 823165A0 FI 823165 A FI823165 A FI 823165A FI 823165 A FI823165 A FI 823165A FI 823165 A0 FI823165 A0 FI 823165A0
Authority
FI
Finland
Prior art keywords
penam
methyl
beta
inhibiterande
dioxider
Prior art date
Application number
FI823165A
Other languages
English (en)
Other versions
FI823165L (fi
Inventor
Wayne Monticello Barth
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI823165A0 publication Critical patent/FI823165A0/fi
Publication of FI823165L publication Critical patent/FI823165L/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/28—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with modified 2-carboxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrrole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FI823165A 1981-09-14 1982-09-13 -laktamas inhibiterande 2- -substituerade-2- metyl(5r) penam-3- -karboxylsyra-1,1-dioxider och deras mellanprodukter FI823165L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/301,995 US4356174A (en) 1981-09-14 1981-09-14 Beta-lactamase inhibiting 2-beta-substituted-2-alpha-methyl-(5R)penam-3-alpha-carboxylic acid 1,1-dioxides and intermediates therefor

Publications (2)

Publication Number Publication Date
FI823165A0 true FI823165A0 (fi) 1982-09-13
FI823165L FI823165L (fi) 1983-03-15

Family

ID=23165806

Family Applications (1)

Application Number Title Priority Date Filing Date
FI823165A FI823165L (fi) 1981-09-14 1982-09-13 -laktamas inhibiterande 2- -substituerade-2- metyl(5r) penam-3- -karboxylsyra-1,1-dioxider och deras mellanprodukter

Country Status (25)

Country Link
US (1) US4356174A (fi)
EP (1) EP0074783B1 (fi)
JP (1) JPS5859990A (fi)
KR (1) KR860001361B1 (fi)
AT (1) ATE14585T1 (fi)
AU (1) AU532401B2 (fi)
CA (1) CA1212378A (fi)
CS (1) CS236681B2 (fi)
DE (1) DE3265082D1 (fi)
DK (1) DK407882A (fi)
ES (1) ES8308566A1 (fi)
FI (1) FI823165L (fi)
GR (1) GR76726B (fi)
HU (1) HU186575B (fi)
IE (1) IE53819B1 (fi)
IL (1) IL66776A (fi)
IN (1) IN159366B (fi)
NO (1) NO823093L (fi)
NZ (1) NZ201895A (fi)
PH (1) PH19442A (fi)
PL (1) PL139272B1 (fi)
PT (1) PT75548B (fi)
SU (1) SU1272995A3 (fi)
YU (1) YU205182A (fi)
ZA (1) ZA826687B (fi)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4760058A (en) * 1984-08-29 1988-07-26 Farmitalia Carlo Erba S.P.A. Penam derivatives
US4861768A (en) * 1986-02-27 1989-08-29 Taiho Pharmaceutical Company, Limited 2 β-substituted thiomethylpenicillin derivatives and their preparation and use
TW383308B (en) * 1993-08-24 2000-03-01 Hoffmann La Roche 2-beta-alkenyl penam sulfones as beta-lactamase inhibitors
ES2178301T3 (es) * 1997-12-29 2002-12-16 Res Corp Technologies Inc Derivados del acido penicilanico 2-beta-sustituido-6-alquilideno como inhibidores de la beta-lactama.
US6407091B1 (en) * 1999-04-15 2002-06-18 Research Corporation Technologies, Inc. β-lactamase inhibiting compounds
WO2003020732A2 (en) * 2001-07-24 2003-03-13 Alamx, L.L.C. 7-alkylidene-3-substituted-3-cephem-4-carboxylates as beta-lactamase inhibitors.
JP2005525399A (ja) * 2002-04-04 2005-08-25 アラムクス エルエルシー セリンおよびメタロ−β−ラクタマーゼの阻害剤
KR100796131B1 (ko) * 2005-04-06 2008-01-21 후지쯔 가부시끼가이샤 휴대형 전자 기기
CN104650119B (zh) * 2015-02-10 2017-04-05 中国科学院长春应用化学研究所 一种β‑内酰胺化合物的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1541832A (en) * 1976-02-11 1979-03-07 Beecham Group Ltd 2-substituted penam derivatives methods for their preparation and compisitions containing them
US4234579A (en) * 1977-06-07 1980-11-18 Pfizer Inc. Penicillanic acid 1,1-dioxides as β-lactamase inhibitors
US4241050A (en) * 1978-09-01 1980-12-23 Pfizer Inc. Penam 1,1-dioxides as beta-lactamase inhibitors
US4244951A (en) * 1979-05-16 1981-01-13 Pfizer Inc. Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide
US4256733A (en) * 1979-09-26 1981-03-17 Pfizer Inc. Acetoxymethyl penam compounds as β-lactamase inhibitors
US4287181A (en) * 1979-10-22 1981-09-01 Pfizer Inc. Derivatives of 6β-hydroxyalkylpenicillanic acids as β-lactamase inhibitors
IL61880A (en) * 1980-01-21 1984-11-30 Bristol Myers Co 2beta-chloromethyl-2alpha-methylpenam-3alpha-carboxylic acid sulfone derivatives,their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
PT75548A (en) 1982-10-01
KR860001361B1 (ko) 1986-09-16
HU186575B (en) 1985-08-28
ES515649A0 (es) 1983-09-16
EP0074783B1 (en) 1985-07-31
CA1212378A (en) 1986-10-07
KR840001581A (ko) 1984-05-07
PL139272B1 (en) 1987-01-31
US4356174A (en) 1982-10-26
IE53819B1 (en) 1989-03-01
SU1272995A3 (ru) 1986-11-23
EP0074783A1 (en) 1983-03-23
JPS6153354B2 (fi) 1986-11-17
ES8308566A1 (es) 1983-09-16
DE3265082D1 (en) 1985-09-05
NO823093L (no) 1983-03-15
FI823165L (fi) 1983-03-15
PH19442A (en) 1986-04-18
GR76726B (fi) 1984-08-30
ZA826687B (en) 1983-07-27
PT75548B (en) 1985-12-09
IN159366B (fi) 1987-05-09
IE822232L (en) 1983-03-14
CS236681B2 (en) 1985-05-15
DK407882A (da) 1983-03-15
YU205182A (en) 1985-03-20
AU8833982A (en) 1983-03-24
PL238200A1 (en) 1985-02-13
AU532401B2 (en) 1983-09-29
JPS5859990A (ja) 1983-04-09
ATE14585T1 (de) 1985-08-15
IL66776A (en) 1985-07-31
NZ201895A (en) 1985-03-20

Similar Documents

Publication Publication Date Title
NO860371L (no) Fremgangsmaate ved fremstilling av peptidaseinhibitorer.
IT1150035B (it) Sistema perfezionato per l'esecuzione di funzioni logiche
IT8021794A0 (it) Pinza per l'applicazione di graffe all'ovidotto.
NO880162L (no) Fremgangsmaate ved fremstilling av nye peptidaseinhibitorer
DK389480A (da) Derivater af 6beta-hydroxyalkyl-penicillansyrer til anvendelse som beta-lactamse-inhibitorer
FI862020A (fi) Komposition och anvaendning av denna foer lakning av metaller fraon vattenloesningar.
IT8004812A0 (it) Procedimento per la riduzione di emissione di nox.
FI823165L (fi) -laktamas inhibiterande 2- -substituerade-2- metyl(5r) penam-3- -karboxylsyra-1,1-dioxider och deras mellanprodukter
PT87642A (pt) Process for the preparation of dopamine-beta-hydroxylase inhibitors
SE8005714L (sv) Acetoximetyl-penamforeningar anvendbara som beta-laktamasinnibitorer
NO880851D0 (no) Fremgangsmaate for fremstilling av nye renin-inhibitorer.
IT8023229A0 (it) Procedimento di seperazione o di purificazione di miscele conl'ausilio di un solido assorbente.
DK160816C (da) Benzoyl-urinstof-derivater, fremgangsmaade til fremstilling af disse, fremgangsmaade til bekaempelse af insektangreb samt insekticidt middel indeholdende disse
IE820342L (en) Penicillins
IT8048641A0 (it) Procedimento di depurazione dell'antibiotico spectinomicina
DK275784A (da) 6-(aminomethyl)penicillansyre-1,1-dioxid-estere, som er hydrolyserbare under fysiologiske betingelser, og aminobeskyttede 6-(aminomethyl)penicillansyre-forbindelser til anvendelse som mellemprodukter herfor
ES513956A0 (es) "procedimiento para la carbonilacion de olefinas y esteres organicos".
IT8148624A0 (it) Procedimento per la purificazione di 2-mercaptobenzotiazolo
FI884827A0 (fi) Anordning foer anslutning av hjaelpinskjutningsenheter till inskjutningsenheter.
FI852537A0 (fi) Foerfaranden och medel vid biologisk behandling.
DK157542C (da) Fremgangsmaade til fremstilling af m-hydroxyphenyl-substituerede forbindelser samt 2-halogen-3-oxo-cyclohex-1-enylforbindelser til brug som udgangsmaterialer herved.
NL7800395A (nl) Nieuwe amino-spiro (oxa(of thia)cycloalkaan- penam)-carbonzuurderivaten en werkwijze voor de bereiding daarvan.
NO158915C (no) Fremgangsmaate for konservering av fiskeraastoff.
RO77509A2 (ro) Procedeu pentru purificarea 1-naftolului
FI873835A0 (fi) Anordning foer beskaerning av smaoskog.

Legal Events

Date Code Title Description
FD Application lapsed

Owner name: PFIZER INC.