FI803849L - Nya acylpeptider farmaceutiska preparat daerav foerfarande foer deras framstaellning och deras anvaendning - Google Patents

Nya acylpeptider farmaceutiska preparat daerav foerfarande foer deras framstaellning och deras anvaendning

Info

Publication number
FI803849L
FI803849L FI803849A FI803849A FI803849L FI 803849 L FI803849 L FI 803849L FI 803849 A FI803849 A FI 803849A FI 803849 A FI803849 A FI 803849A FI 803849 L FI803849 L FI 803849L
Authority
FI
Finland
Prior art keywords
acylpeptider
daerav
nya
foerfarande
amino acids
Prior art date
Application number
FI803849A
Other languages
English (en)
Finnish (fi)
Inventor
Hans Rink
Peter Sieber
Bruno Kamber
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI803849L publication Critical patent/FI803849L/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/655Somatostatins
    • C07K14/6555Somatostatins at least 1 amino acid in D-form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/16Somatostatin; related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI803849A 1979-12-14 1980-12-10 Nya acylpeptider farmaceutiska preparat daerav foerfarande foer deras framstaellning och deras anvaendning FI803849L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1109679 1979-12-14

Publications (1)

Publication Number Publication Date
FI803849L true FI803849L (fi) 1981-06-15

Family

ID=4370005

Family Applications (1)

Application Number Title Priority Date Filing Date
FI803849A FI803849L (fi) 1979-12-14 1980-12-10 Nya acylpeptider farmaceutiska preparat daerav foerfarande foer deras framstaellning och deras anvaendning

Country Status (18)

Country Link
US (1) US4369179A (ja)
EP (1) EP0030920B1 (ja)
JP (1) JPS5692850A (ja)
KR (2) KR850000415B1 (ja)
AT (1) ATE6251T1 (ja)
AU (1) AU544256B2 (ja)
CA (1) CA1161033A (ja)
DD (1) DD154098A5 (ja)
DE (1) DE3066654D1 (ja)
DK (1) DK532180A (ja)
ES (1) ES497696A0 (ja)
FI (1) FI803849L (ja)
GR (1) GR73621B (ja)
IL (1) IL61696A0 (ja)
NO (1) NO803757L (ja)
NZ (1) NZ195817A (ja)
PT (1) PT72191B (ja)
ZA (1) ZA807796B (ja)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0083305B1 (de) * 1981-12-24 1985-07-10 Ciba-Geigy Ag Cyclische Octapeptide und pharmazeutische Präparate davon, sowie Verfahren zur Herstellung derselben und ihre Anwendung
FR2522655B1 (fr) * 1982-03-05 1987-03-06 Sanofi Sa Analogues de la somatostatine possedant une liaison du type hydrazide et medicaments en contenant
EP0113029B1 (en) * 1982-12-06 1989-04-19 Merck & Co. Inc. Dicyclic hexapeptides, processes for their preparation and pharmaceutical compositions containing them
US4485101A (en) * 1983-10-11 1984-11-27 Administrators Of The Tulane Educational Fund Peptides
US4612302A (en) * 1983-11-14 1986-09-16 Brigham And Women's Hospital Clinical use of somatostatin analogues
US4650787A (en) * 1985-04-25 1987-03-17 Schally Andrew Victor Biologically active octapeptides
CA2053250A1 (en) * 1989-04-26 1990-10-27 David H. Coy Linear somatostatin analogs
US5633263A (en) * 1989-04-26 1997-05-27 The Administrators Of The Tulane Educational Fund Linear somatostatin analogs
US5504069A (en) * 1993-02-11 1996-04-02 Biomeasure, Inc. Inhibition of trauma-induced tumor growth
US5597894A (en) * 1995-06-05 1997-01-28 The Louisiana State University Medical Center Foundation Multi-tyrosinated somatostatin analogs
US5905140A (en) * 1996-07-11 1999-05-18 Novo Nordisk A/S, Novo Alle Selective acylation method
US6355613B1 (en) * 1996-07-31 2002-03-12 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
US6004928A (en) * 1997-05-13 1999-12-21 Biomeasure, Incorporated Method of treating hyperlipidemia
ATE262921T1 (de) * 1997-05-13 2004-04-15 Sod Conseils Rech Applic Somatostatin und somatostatin agoniste zur behandlung der insulinsunempfindlichkeit und syndrome x
ES2202864T3 (es) * 1997-05-13 2004-04-01 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Agonistas de la somatostatina para disminuir el peso corporal.
WO1998051330A1 (en) * 1997-05-13 1998-11-19 Societe De Conseils De Recherches Et D'applications Scientifiques S.A. (S.C.R.A.S.) Method and compositions for treating hyperlipidemia and other conditions
US5968903A (en) * 1998-05-07 1999-10-19 Biomeasure, Incorporated Inhibition of H. pylori proliferation
EP1305338A2 (en) * 2000-08-02 2003-05-02 Theratechnologies Inc. Modified peptides with increased potency
WO2002100888A1 (en) 2001-06-08 2002-12-19 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Somatostatin-dopamine chimeric analogs
EP1624884A4 (en) 2003-04-22 2009-08-05 Ipsen Pharma SOMATOSTATIN VECTORS
EP3473643A1 (en) 2008-06-12 2019-04-24 Ipsen Bioinnovation Limited Fusion proteins for use in the treatemnt of cancer
JP5728380B2 (ja) 2008-06-12 2015-06-03 シンタクシン リミテッドSyntaxin Limited 神経内分泌疾患の抑制
GB0820970D0 (en) 2008-11-17 2008-12-24 Syntaxin Ltd Suppression of cancer
JP6869720B2 (ja) 2013-06-13 2021-05-12 アンチセンス セラピューティクス リミテッド 併用療法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3944590A (en) * 1967-01-25 1976-03-16 Ciba-Geigy Corporation Process for the temporary protection of amino groups in peptide syntheses
US3875207A (en) * 1967-01-25 1975-04-01 Ciba Geigy Corp Process for the temporary protection of amino groups in peptide syntheses
US3725380A (en) * 1969-04-05 1973-04-03 Hoechst Ag Method of synthesizing peptides in the presence of a carbodiimide and a 1-hydroxy-benzotriazole
CH517705A (de) * 1969-12-16 1972-01-15 Ciba Geigy Ag Verfahren zur Herstellung von Cystin-haltigen Peptiden
DE2202613C3 (de) * 1972-01-20 1974-06-20 Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt Verfahren zur Herstellung von Peptiden
CH577464A5 (ja) * 1972-09-22 1976-07-15 Ciba Geigy Ag
US3882098A (en) * 1974-01-03 1975-05-06 American Home Prod Synthesis of des-Ala{hu 1{b , Gly{hu 2{b , Asn{hu 5{b -SRIF and intermediates
US4113714A (en) * 1975-01-03 1978-09-12 American Home Products Corporation [Des-Ala1, Gly2 -desamino-Cys3 ]somatostatin
US4130554A (en) * 1975-04-08 1978-12-19 Merck & Co., Inc. Process for preparing somatostatin analog
US4000259A (en) * 1975-06-16 1976-12-28 American Home Products Corporation Cyclic dodecapeptide analogs of somatostatin and intermediates
US3988304A (en) * 1975-08-25 1976-10-26 American Home Products Corporation Cyclic dodecapeptide derivatives of somatostatin and intermediates thereof
CA1083143A (en) * 1976-01-02 1980-08-05 Nedumparambil A. Abraham Carba derivatives of somatostatin and process therefor
US4062816A (en) * 1976-03-11 1977-12-13 Eli Lilly And Company D-Ala5 -somatostatin and intermediates thereto
US4098782A (en) * 1977-03-14 1978-07-04 American Home Products Corporation (His5)-somatostatin and analogues thereof
US4118380A (en) * 1977-07-25 1978-10-03 Ayerst, Mckenna & Harrison Limited Decapeptide analogs of somatostatin
US4115554A (en) * 1977-08-29 1978-09-19 Merck & Co., Inc. Somatostatin analogs
LU78191A1 (de) * 1977-09-28 1979-05-25 Ciba Geigy Ag Verfahren zur herstellung von neuen cyclopeptiden
US4140767A (en) * 1977-12-01 1979-02-20 Merck & Co., Inc. Somatostatin analogs
US4202802A (en) * 1978-10-02 1980-05-13 Eli Lilly And Company Peptides related to somatostatin
US4191754A (en) * 1979-02-28 1980-03-04 Merck & Co., Inc. Bicyclic somatostatin analogs
US4235886A (en) * 1979-10-31 1980-11-25 Merck & Co., Inc. Cyclic hexapeptide somatostatin analogs

Also Published As

Publication number Publication date
DK532180A (da) 1981-06-15
DD154098A5 (de) 1982-02-24
ATE6251T1 (de) 1984-03-15
DE3066654D1 (en) 1984-03-22
NO803757L (no) 1981-06-15
EP0030920A3 (en) 1981-11-04
EP0030920A2 (de) 1981-06-24
NZ195817A (en) 1984-07-06
GR73621B (ja) 1984-03-26
KR830004216A (ko) 1983-07-06
AU6534580A (en) 1981-06-18
ES8200861A1 (es) 1981-11-16
EP0030920B1 (de) 1984-02-15
JPS5692850A (en) 1981-07-27
US4369179A (en) 1983-01-18
ZA807796B (en) 1982-01-27
IL61696A0 (en) 1981-01-30
PT72191B (de) 1982-01-13
CA1161033A (en) 1984-01-24
ES497696A0 (es) 1981-11-16
KR850000414B1 (ko) 1985-03-26
AU544256B2 (en) 1985-05-23
PT72191A (de) 1981-01-01
KR850000415B1 (ko) 1985-03-26

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Owner name: CIBA-GEIGY AG