FI68850B - Polykarbonatpolyetersampolymermembran foerfarande foer dess frmstaellning samt anvaendning av denna vid hemodialys - Google Patents
Polykarbonatpolyetersampolymermembran foerfarande foer dess frmstaellning samt anvaendning av denna vid hemodialys Download PDFInfo
- Publication number
- FI68850B FI68850B FI802519A FI802519A FI68850B FI 68850 B FI68850 B FI 68850B FI 802519 A FI802519 A FI 802519A FI 802519 A FI802519 A FI 802519A FI 68850 B FI68850 B FI 68850B
- Authority
- FI
- Finland
- Prior art keywords
- membrane
- film
- polycarbonate
- solvent
- weight
- Prior art date
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- 101100148710 Clarkia breweri SAMT gene Proteins 0.000 title 1
- 239000012528 membrane Substances 0.000 claims abstract description 89
- 238000000034 method Methods 0.000 claims abstract description 25
- 239000002904 solvent Substances 0.000 claims abstract description 21
- 238000000108 ultra-filtration Methods 0.000 claims abstract description 19
- 229920000642 polymer Polymers 0.000 claims abstract description 11
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims abstract description 10
- 229920001400 block copolymer Polymers 0.000 claims abstract description 9
- 230000008569 process Effects 0.000 claims abstract description 9
- IISBACLAFKSPIT-UHFFFAOYSA-N bisphenol A Chemical compound C=1C=C(O)C=CC=1C(C)(C)C1=CC=C(O)C=C1 IISBACLAFKSPIT-UHFFFAOYSA-N 0.000 claims abstract description 7
- 229920001577 copolymer Polymers 0.000 claims abstract description 7
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims abstract description 6
- 238000000502 dialysis Methods 0.000 claims description 17
- 230000035699 permeability Effects 0.000 claims description 17
- 239000004721 Polyphenylene oxide Substances 0.000 claims description 14
- 229920000570 polyether Polymers 0.000 claims description 14
- 238000004090 dissolution Methods 0.000 claims description 11
- 238000004519 manufacturing process Methods 0.000 claims description 10
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 9
- 239000000203 mixture Substances 0.000 claims description 8
- 238000001914 filtration Methods 0.000 claims description 7
- 229930003451 Vitamin B1 Natural products 0.000 claims description 5
- -1 polyethylene terephthalate Polymers 0.000 claims description 5
- 229960003495 thiamine Drugs 0.000 claims description 5
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 claims description 5
- 235000010374 vitamin B1 Nutrition 0.000 claims description 5
- 239000011691 vitamin B1 Substances 0.000 claims description 5
- 238000001631 haemodialysis Methods 0.000 claims description 4
- 230000000322 hemodialysis Effects 0.000 claims description 4
- 239000008280 blood Substances 0.000 claims description 3
- 210000004369 blood Anatomy 0.000 claims description 3
- 229920000139 polyethylene terephthalate Polymers 0.000 claims description 3
- 239000005020 polyethylene terephthalate Substances 0.000 claims description 3
- 239000000126 substance Substances 0.000 claims description 3
- 239000000654 additive Substances 0.000 claims description 2
- GSCLMSFRWBPUSK-UHFFFAOYSA-N beta-Butyrolactone Chemical compound CC1CC(=O)O1 GSCLMSFRWBPUSK-UHFFFAOYSA-N 0.000 claims description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 2
- 239000008240 homogeneous mixture Substances 0.000 claims description 2
- FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 claims 1
- 230000001419 dependent effect Effects 0.000 claims 1
- 229930185605 Bisphenol Natural products 0.000 abstract 1
- 230000001376 precipitating effect Effects 0.000 abstract 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 21
- 239000000243 solution Substances 0.000 description 20
- 238000001035 drying Methods 0.000 description 19
- 229930003779 Vitamin B12 Natural products 0.000 description 6
- AGVAZMGAQJOSFJ-WZHZPDAFSA-M cobalt(2+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+2].N#[C-].[N-]([C@@H]1[C@H](CC(N)=O)[C@@]2(C)CCC(=O)NC[C@@H](C)OP(O)(=O)O[C@H]3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)\C2=C(C)/C([C@H](C\2(C)C)CCC(N)=O)=N/C/2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O AGVAZMGAQJOSFJ-WZHZPDAFSA-M 0.000 description 6
- 239000007788 liquid Substances 0.000 description 6
- 238000005259 measurement Methods 0.000 description 6
- 235000019163 vitamin B12 Nutrition 0.000 description 6
- 239000011715 vitamin B12 Substances 0.000 description 6
- 235000019441 ethanol Nutrition 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 238000002360 preparation method Methods 0.000 description 5
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 4
- 238000005406 washing Methods 0.000 description 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- CQGRLHBOVUGVEA-UHFFFAOYSA-N OOOOOOOOOOOOOOO Chemical compound OOOOOOOOOOOOOOO CQGRLHBOVUGVEA-UHFFFAOYSA-N 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 238000001704 evaporation Methods 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- YEJRWHAVMIAJKC-UHFFFAOYSA-N 4-Butyrolactone Chemical compound O=C1CCCO1 YEJRWHAVMIAJKC-UHFFFAOYSA-N 0.000 description 2
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 2
- 239000004698 Polyethylene Substances 0.000 description 2
- 239000013256 coordination polymer Substances 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 230000008020 evaporation Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 229920000573 polyethylene Polymers 0.000 description 2
- 238000001556 precipitation Methods 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- QMMJWQMCMRUYTG-UHFFFAOYSA-N 1,2,4,5-tetrachloro-3-(trifluoromethyl)benzene Chemical compound FC(F)(F)C1=C(Cl)C(Cl)=CC(Cl)=C1Cl QMMJWQMCMRUYTG-UHFFFAOYSA-N 0.000 description 1
- MBIQENSCDNJOIY-UHFFFAOYSA-N 2-hydroxy-2-methylbutyric acid Chemical compound CCC(C)(O)C(O)=O MBIQENSCDNJOIY-UHFFFAOYSA-N 0.000 description 1
- 102000018832 Cytochromes Human genes 0.000 description 1
- 108010052832 Cytochromes Proteins 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 229920001202 Inulin Polymers 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000001476 alcoholic effect Effects 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 125000005587 carbonate group Chemical group 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000000593 degrading effect Effects 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000008098 formaldehyde solution Substances 0.000 description 1
- 239000011796 hollow space material Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- JYJIGFIDKWBXDU-MNNPPOADSA-N inulin Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)OC[C@]1(OC[C@]2(OC[C@]3(OC[C@]4(OC[C@]5(OC[C@]6(OC[C@]7(OC[C@]8(OC[C@]9(OC[C@]%10(OC[C@]%11(OC[C@]%12(OC[C@]%13(OC[C@]%14(OC[C@]%15(OC[C@]%16(OC[C@]%17(OC[C@]%18(OC[C@]%19(OC[C@]%20(OC[C@]%21(OC[C@]%22(OC[C@]%23(OC[C@]%24(OC[C@]%25(OC[C@]%26(OC[C@]%27(OC[C@]%28(OC[C@]%29(OC[C@]%30(OC[C@]%31(OC[C@]%32(OC[C@]%33(OC[C@]%34(OC[C@]%35(OC[C@]%36(O[C@@H]%37[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O%37)O)[C@H]([C@H](O)[C@@H](CO)O%36)O)[C@H]([C@H](O)[C@@H](CO)O%35)O)[C@H]([C@H](O)[C@@H](CO)O%34)O)[C@H]([C@H](O)[C@@H](CO)O%33)O)[C@H]([C@H](O)[C@@H](CO)O%32)O)[C@H]([C@H](O)[C@@H](CO)O%31)O)[C@H]([C@H](O)[C@@H](CO)O%30)O)[C@H]([C@H](O)[C@@H](CO)O%29)O)[C@H]([C@H](O)[C@@H](CO)O%28)O)[C@H]([C@H](O)[C@@H](CO)O%27)O)[C@H]([C@H](O)[C@@H](CO)O%26)O)[C@H]([C@H](O)[C@@H](CO)O%25)O)[C@H]([C@H](O)[C@@H](CO)O%24)O)[C@H]([C@H](O)[C@@H](CO)O%23)O)[C@H]([C@H](O)[C@@H](CO)O%22)O)[C@H]([C@H](O)[C@@H](CO)O%21)O)[C@H]([C@H](O)[C@@H](CO)O%20)O)[C@H]([C@H](O)[C@@H](CO)O%19)O)[C@H]([C@H](O)[C@@H](CO)O%18)O)[C@H]([C@H](O)[C@@H](CO)O%17)O)[C@H]([C@H](O)[C@@H](CO)O%16)O)[C@H]([C@H](O)[C@@H](CO)O%15)O)[C@H]([C@H](O)[C@@H](CO)O%14)O)[C@H]([C@H](O)[C@@H](CO)O%13)O)[C@H]([C@H](O)[C@@H](CO)O%12)O)[C@H]([C@H](O)[C@@H](CO)O%11)O)[C@H]([C@H](O)[C@@H](CO)O%10)O)[C@H]([C@H](O)[C@@H](CO)O9)O)[C@H]([C@H](O)[C@@H](CO)O8)O)[C@H]([C@H](O)[C@@H](CO)O7)O)[C@H]([C@H](O)[C@@H](CO)O6)O)[C@H]([C@H](O)[C@@H](CO)O5)O)[C@H]([C@H](O)[C@@H](CO)O4)O)[C@H]([C@H](O)[C@@H](CO)O3)O)[C@H]([C@H](O)[C@@H](CO)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 JYJIGFIDKWBXDU-MNNPPOADSA-N 0.000 description 1
- 229940029339 inulin Drugs 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 239000010410 layer Substances 0.000 description 1
- 239000005022 packaging material Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 229960004583 pranlukast Drugs 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 239000002344 surface layer Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000004627 transmission electron microscopy Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
- B01D71/06—Organic material
- B01D71/76—Macromolecular material not specifically provided for in a single one of groups B01D71/08 - B01D71/74
- B01D71/80—Block polymers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/02—Hollow fibre modules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
- B01D69/02—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
- B01D71/06—Organic material
- B01D71/52—Polyethers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G64/00—Macromolecular compounds obtained by reactions forming a carbonic ester link in the main chain of the macromolecule
- C08G64/18—Block or graft polymers
- C08G64/183—Block or graft polymers containing polyether sequences
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
- B01D71/06—Organic material
- B01D71/50—Polycarbonates
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2913—Rod, strand, filament or fiber
- Y10T428/2973—Particular cross section
- Y10T428/2975—Tubular or cellular
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Polyesters Or Polycarbonates (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
- Manufacture Of Macromolecular Shaped Articles (AREA)
- External Artificial Organs (AREA)
- Preparing Plates And Mask In Photomechanical Process (AREA)
- Carbon And Carbon Compounds (AREA)
- Manufacturing Of Electric Cables (AREA)
- Materials For Medical Uses (AREA)
- Shaping Of Tube Ends By Bending Or Straightening (AREA)
- Closing And Opening Devices For Wings, And Checks For Wings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Treatment Of Water By Ion Exchange (AREA)
Claims (18)
1. Membran i form av en plahhinna, slanghinna eller ihälig ti ad av en polykarbonatpolyeterblocksamapolymer, som innehäller 5-35 vikt-% upprepade alkyleneterkarbonatenheter i polyetenoxid-block, vilkas medelmolekylvikt är over 1000, och 95-65 vikt-% upprepade bisfenol-A-karbonatenheter, och vilken membran framställts medelst strängpressning av polykarbonatpolyeterblocksampolymerens V'-butyrolaktonlösning till ett icke lösande medel, kanne- t e c k n a d därav, att polyetylenoxidblockens medelmolekylvikt är 1 000 - 20 000, membranen är till sin struktur isotropisk och saknar ytmembran, sampolymerens gränsviskositet är 180-300 ml/g, uppmätt i kloroform vid 25°C, och ultrafiltreringshastigheten är är 4-200 ml/h.m^.mm Hg.
2. Membran enligt patentkravet 1, kännetecknad därav, att den dialytiska permeabiliteten för vitamin B12, uppmätt vid 20°C, är till sitt talvärde beroende av ultrafiltreringsför-magan pä följande sätt: DL01 „ = (2,5 — 0,25)VUFL.
3. Membran enligt patentkravet 1, kännetecknad därav, att polykarbonatpolyetersampolymeren innehäller 7-13 vikt-% upprepade polyetylenoxidenheter och 93-87 vikt-% upprepade bis- fenol-A-karbonatenheter, och att polyetylenoxidblockens medelmolekylvikt är 6 000 - 10 000.
4. Membran enligt patentkravet 3, kännetecknad därav, att den innehäller mindre än 0,5 vikt-% hjälp- och främmande ämnen.
5. Membran enligt patentkravet 4, kännetecknad därav, att den dialytiska permeabiliteten för vitamin B12, uppmätt vid 20°C, beror av ultrafiltreringsförmägan pä följande sätt: DLB12 = (1'3 ~ 0#2)\/ljFL.
6. Förfarande för framställning av en membran enligt pa-tentkraven 1-5, kännetecknat därav, att i ett första lösningsskede blandas polykarbonatpolyeterblocksampolymer och Y -butyrolakton vid 80-120°C tili en homogen blandning, i ett andra lösningsskede upphettas blandningen vid 140-180°C mindre än 10 minuter, varvid en äkta lösning bildas, som efter filtrering
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2932761 | 1979-08-13 | ||
| DE19792932761 DE2932761A1 (de) | 1979-08-13 | 1979-08-13 | Polycarbonat-polyaether-copolymermembran |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI802519A FI802519A (fi) | 1981-02-14 |
| FI68850B true FI68850B (fi) | 1985-07-31 |
| FI68850C FI68850C (fi) | 1985-11-11 |
Family
ID=6078355
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI802519A FI68850C (fi) | 1979-08-13 | 1980-08-11 | Polykarbonatpolyetersampolymermembran foerfarande foer dess frmstaellning samt anvaendning av denna vid hemodialys |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4686044A (sv) |
| EP (1) | EP0024600B1 (sv) |
| JP (1) | JPS5927604B2 (sv) |
| AT (1) | ATE5147T1 (sv) |
| AU (1) | AU532357B2 (sv) |
| CA (1) | CA1173211A (sv) |
| DE (2) | DE2932761A1 (sv) |
| DK (1) | DK154775C (sv) |
| ES (2) | ES494186A0 (sv) |
| FI (1) | FI68850C (sv) |
| IE (1) | IE50102B1 (sv) |
| NO (1) | NO155349C (sv) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE423106B (sv) * | 1980-07-25 | 1982-04-13 | Gambro Dialysatoren | Plasmaferesmembran samt sett att tillverka detta |
| EP0046817B1 (en) * | 1980-09-01 | 1984-11-28 | Gambro, Inc. | Dry polycarbonate membrane and process of manufacture |
| EP0046816A1 (en) * | 1980-09-01 | 1982-03-10 | Gambro, Inc. | Polycarbonate hemofiltration membrane and method of hemofiltering using such a membrane |
| JPS5759548A (en) * | 1980-09-22 | 1982-04-09 | Ganburo Inc | Substantially dry sag and wrinkle free stabilized translucent polyether polycarbonate block copolymer membrane and preparation thereof |
| SE446505B (sv) * | 1982-11-16 | 1986-09-22 | Gambro Dialysatoren | Membran samt sett att framstella detta |
| EP0135760A1 (de) * | 1983-08-19 | 1985-04-03 | Bayer Ag | Polyether-Polycarbonate für Dialysemembranen |
| US5658995A (en) * | 1995-11-27 | 1997-08-19 | Rutgers, The State University | Copolymers of tyrosine-based polycarbonate and poly(alkylene oxide) |
| US6048521A (en) * | 1997-11-07 | 2000-04-11 | Rutgers, The State University | Copolymers of tyrosine-based polyarlates and poly(alkylene oxides) |
| US8527026B2 (en) | 1997-03-04 | 2013-09-03 | Dexcom, Inc. | Device and method for determining analyte levels |
| US6001067A (en) | 1997-03-04 | 1999-12-14 | Shults; Mark C. | Device and method for determining analyte levels |
| US7192450B2 (en) | 2003-05-21 | 2007-03-20 | Dexcom, Inc. | Porous membranes for use with implantable devices |
| US6741877B1 (en) * | 1997-03-04 | 2004-05-25 | Dexcom, Inc. | Device and method for determining analyte levels |
| US6862465B2 (en) | 1997-03-04 | 2005-03-01 | Dexcom, Inc. | Device and method for determining analyte levels |
| US6558321B1 (en) | 1997-03-04 | 2003-05-06 | Dexcom, Inc. | Systems and methods for remote monitoring and modulation of medical devices |
| US20050033132A1 (en) | 1997-03-04 | 2005-02-10 | Shults Mark C. | Analyte measuring device |
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Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE593044A (sv) * | 1959-07-17 | |||
| US3448185A (en) * | 1967-03-28 | 1969-06-03 | Monsanto Co | Melt-spinning of filaments |
| GB1500937A (en) * | 1974-03-26 | 1978-02-15 | Us Health | Process for producing a polycarbonate hemodialysis membrane |
| US4160791A (en) * | 1974-03-26 | 1979-07-10 | The United States Of America As Represented By The Secretary Of The Department Of Health, Education And Welfare | Polycarbonate membranes and production thereof |
| GB1507921A (en) * | 1974-04-01 | 1978-04-19 | Gen Electric | Membranes |
| DE2705735C3 (de) * | 1977-02-11 | 1982-05-19 | Akzo Gmbh, 5600 Wuppertal | Dialysemembran für die Hämodialyse |
-
1979
- 1979-08-13 DE DE19792932761 patent/DE2932761A1/de active Granted
-
1980
- 1980-07-18 NO NO802169A patent/NO155349C/no unknown
- 1980-08-08 DE DE8080104678T patent/DE3065418D1/de not_active Expired
- 1980-08-08 EP EP80104678A patent/EP0024600B1/de not_active Expired
- 1980-08-08 AT AT80104678T patent/ATE5147T1/de not_active IP Right Cessation
- 1980-08-11 CA CA000357942A patent/CA1173211A/en not_active Expired
- 1980-08-11 FI FI802519A patent/FI68850C/fi not_active IP Right Cessation
- 1980-08-12 DK DK347480A patent/DK154775C/da active
- 1980-08-12 ES ES494186A patent/ES494186A0/es active Granted
- 1980-08-12 JP JP55109906A patent/JPS5927604B2/ja not_active Expired
- 1980-08-12 IE IE1692/80A patent/IE50102B1/en not_active IP Right Cessation
- 1980-08-13 AU AU61405/80A patent/AU532357B2/en not_active Ceased
- 1980-10-07 ES ES495688A patent/ES8106412A1/es not_active Expired
-
1985
- 1985-12-09 US US06/807,766 patent/US4686044A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DK347480A (da) | 1981-02-14 |
| ES8103656A1 (es) | 1981-03-16 |
| NO155349B (no) | 1986-12-08 |
| DE3065418D1 (en) | 1983-12-01 |
| FI68850C (fi) | 1985-11-11 |
| CA1173211A (en) | 1984-08-28 |
| DE2932761A1 (de) | 1981-02-26 |
| FI802519A (fi) | 1981-02-14 |
| ES495688A0 (es) | 1981-07-01 |
| IE801692L (en) | 1981-02-13 |
| NO155349C (no) | 1987-03-18 |
| DK154775C (da) | 1989-05-01 |
| US4686044A (en) | 1987-08-11 |
| AU6140580A (en) | 1981-08-27 |
| IE50102B1 (en) | 1986-02-19 |
| ES8106412A1 (es) | 1981-07-01 |
| DE2932761C2 (sv) | 1987-11-19 |
| AU532357B2 (en) | 1983-09-29 |
| ATE5147T1 (de) | 1983-11-15 |
| EP0024600A1 (de) | 1981-03-11 |
| JPS5927604B2 (ja) | 1984-07-06 |
| EP0024600B1 (de) | 1983-10-26 |
| DK154775B (da) | 1988-12-19 |
| JPS5636964A (en) | 1981-04-10 |
| NO802169L (no) | 1981-02-16 |
| ES494186A0 (es) | 1981-03-16 |
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| MM | Patent lapsed | ||
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Owner name: AKZO N.V. |