FI64371C - Foerfarande foer framstaellning av kardiovaskulaera 5h,7h-imidazo(4,5-h)-isokinolin-4,6-dioner - Google Patents

Foerfarande foer framstaellning av kardiovaskulaera 5h,7h-imidazo(4,5-h)-isokinolin-4,6-dioner Download PDF

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Publication number
FI64371C
FI64371C FI782011A FI782011A FI64371C FI 64371 C FI64371 C FI 64371C FI 782011 A FI782011 A FI 782011A FI 782011 A FI782011 A FI 782011A FI 64371 C FI64371 C FI 64371C
Authority
FI
Finland
Prior art keywords
group
general formula
phenyl
isoquinoline
imidazo
Prior art date
Application number
FI782011A
Other languages
English (en)
Finnish (fi)
Other versions
FI782011A (fi
FI64371B (fi
Inventor
Volkhard Austel
Eberhard Kutter
Joachim Heider
Wolfgang Eberlein
Willi Diederen
Walter Haarmann
Walter Kobinger
Christian Lillie
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE2732906A priority Critical patent/DE2732906C2/de
Priority claimed from DE2732906A external-priority patent/DE2732906C2/de
Priority claimed from DE19772732951 external-priority patent/DE2732951A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of FI782011A publication Critical patent/FI782011A/fi
Priority to DE19792921912 priority patent/DE2921912A1/de
Application granted granted Critical
Publication of FI64371B publication Critical patent/FI64371B/fi
Publication of FI64371C publication Critical patent/FI64371C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI782011A 1977-07-21 1978-06-22 Foerfarande foer framstaellning av kardiovaskulaera 5h,7h-imidazo(4,5-h)-isokinolin-4,6-dioner FI64371C (fi)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DE2732906A DE2732906C2 (de) 1977-07-21 1977-07-21 In 5-Stellung durch einen Aminoalkylrest substituierte Imidazo-isochinolin-dione, Verfahren zu ihrer Herstellung und Arzneimittel
DE19792921912 DE2921912A1 (de) 1977-07-21 1979-05-30 2-phenyl-5-(3-aethylaminopropyl)- 7,7-dimethyl-5h,7h-imidazo eckige klammer auf 4,5-h eckige klammer zu isochinolin-4,6-dion und dessen verwendung als arzneimittel

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE2732906A DE2732906C2 (de) 1977-07-21 1977-07-21 In 5-Stellung durch einen Aminoalkylrest substituierte Imidazo-isochinolin-dione, Verfahren zu ihrer Herstellung und Arzneimittel
DE2732906 1977-07-21
DE19772732951 DE2732951A1 (de) 1977-07-21 1977-07-21 Neue imidazo-isochinolin-dione
DE2732951 1977-07-21

Publications (3)

Publication Number Publication Date
FI782011A FI782011A (fi) 1979-01-22
FI64371B FI64371B (fi) 1983-07-29
FI64371C true FI64371C (fi) 1983-11-10

Family

ID=25772367

Family Applications (1)

Application Number Title Priority Date Filing Date
FI782011A FI64371C (fi) 1977-07-21 1978-06-22 Foerfarande foer framstaellning av kardiovaskulaera 5h,7h-imidazo(4,5-h)-isokinolin-4,6-dioner

Country Status (29)

Country Link
US (1) US4176184A (xx)
JP (1) JPS5422400A (xx)
AT (1) AT366383B (xx)
AU (1) AU519769B2 (xx)
BG (1) BG30021A3 (xx)
CA (1) CA1091232A (xx)
CH (1) CH642367A5 (xx)
CS (1) CS204032B2 (xx)
DD (1) DD137933A5 (xx)
DK (1) DK323378A (xx)
ES (4) ES471254A1 (xx)
FI (1) FI64371C (xx)
FR (1) FR2398069A1 (xx)
GB (1) GB2002751B (xx)
GR (1) GR65025B (xx)
HK (1) HK20685A (xx)
HU (1) HU181000B (xx)
IL (1) IL55168A (xx)
IT (1) IT1107653B (xx)
LU (1) LU80001A1 (xx)
NL (1) NL7807760A (xx)
NO (1) NO149314C (xx)
NZ (1) NZ187916A (xx)
PL (1) PL110398B1 (xx)
PT (1) PT68329A (xx)
SE (1) SE441746B (xx)
SG (1) SG185G (xx)
SU (1) SU688129A3 (xx)
YU (1) YU40340B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3531678A1 (de) * 1985-09-05 1987-03-12 Boehringer Mannheim Gmbh Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
JP2558707Y2 (ja) * 1986-06-25 1998-01-14 松下電工 株式会社 蓄積式防排煙受信機
DE4027592A1 (de) * 1990-08-31 1992-03-05 Beiersdorf Ag Neue pyrrolobenzimidazole, imidazobenzoxazinone und imidazochinolone, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
DE19918211A1 (de) 1999-04-22 2000-10-26 Basf Ag Cycloalkylsubstituierte Benzimidazole, deren Herstellung und Anwendung
ATE277044T1 (de) * 1999-10-06 2004-10-15 Boehringer Ingelheim Pharma Heterocyclische verbindungen verwendbar als tyrosinkinase inhibitoren
US6506769B2 (en) * 1999-10-06 2003-01-14 Boehringer Ingelheim Pharmaceuticals, Inc. Heterocyclic compounds useful as inhibitors of tyrosine kinases
WO2002014319A2 (en) * 2000-08-11 2002-02-21 Boehringer Ingelheim Pharmaceuticals, Inc. Heterocyclic compounds useful as inhibitors of tyrosine kinases
CA2541618C (en) * 2003-10-30 2011-12-13 Boehringer Ingelheim (Canada) Ltd. Rsv polymerase inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE368009B (xx) * 1971-09-16 1974-06-17 Kabi Ab
US3878206A (en) * 1973-06-06 1975-04-15 Morton Norwich Products Inc 9-(Substituted amino)imidazo{8 4,5-f{9 quinolines
US3919238A (en) * 1973-06-06 1975-11-11 Morton Norwich Products Inc 9-(Substituted amino)imidazo(4,5-f) quinolines

Also Published As

Publication number Publication date
SE7808018L (sv) 1979-01-22
HK20685A (en) 1985-03-29
HU181000B (en) 1983-05-30
FR2398069A1 (fr) 1979-02-16
AU3821078A (en) 1980-01-24
IL55168A (en) 1981-09-13
FI782011A (fi) 1979-01-22
NO782498L (no) 1979-01-23
IL55168A0 (en) 1978-09-29
ES471254A1 (es) 1979-10-01
SU688129A3 (ru) 1979-09-25
AT366383B (de) 1982-04-13
LU80001A1 (de) 1979-09-06
BG30021A3 (en) 1981-03-16
SG185G (en) 1985-06-14
ES476168A1 (es) 1979-05-16
PT68329A (de) 1978-08-01
NL7807760A (nl) 1979-01-23
GB2002751A (en) 1979-02-28
NO149314B (no) 1983-12-19
JPS5422400A (en) 1979-02-20
YU40340B (en) 1985-12-31
IT7850337A0 (it) 1978-07-17
CS204032B2 (en) 1981-03-31
JPS6112912B2 (xx) 1986-04-10
GB2002751B (en) 1982-02-10
NO149314C (no) 1984-03-28
DD137933A5 (de) 1979-10-03
ES476167A1 (es) 1979-04-16
FR2398069B1 (xx) 1981-05-22
AU519769B2 (en) 1981-12-24
GR65025B (en) 1980-06-16
SE441746B (sv) 1985-11-04
PL208543A1 (pl) 1979-05-21
FI64371B (fi) 1983-07-29
DK323378A (da) 1979-01-22
IT1107653B (it) 1985-11-25
US4176184A (en) 1979-11-27
CA1091232A (en) 1980-12-09
PL110398B1 (en) 1980-07-31
ATA498878A (de) 1981-08-15
CH642367A5 (de) 1984-04-13
NZ187916A (en) 1981-05-01
ES476166A1 (es) 1979-06-01
YU174778A (en) 1983-02-28

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Owner name: DR. KARL THOMAE GMBH