FI61866C - Foerfarande foer framstaellning av diuretisk eller saluretisk (1-oxo-2-fenyl- eller -tienyl-2-substituerad-5-indanyloxi)aettiksyra eller dess derivat - Google Patents

Foerfarande foer framstaellning av diuretisk eller saluretisk (1-oxo-2-fenyl- eller -tienyl-2-substituerad-5-indanyloxi)aettiksyra eller dess derivat Download PDF

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Publication number
FI61866C
FI61866C FI2789/74A FI278974A FI61866C FI 61866 C FI61866 C FI 61866C FI 2789/74 A FI2789/74 A FI 2789/74A FI 278974 A FI278974 A FI 278974A FI 61866 C FI61866 C FI 61866C
Authority
FI
Finland
Prior art keywords
formula
phenyl
dichloro
methyl
compound
Prior art date
Application number
FI2789/74A
Other languages
English (en)
Finnish (fi)
Other versions
FI278974A (sv
FI61866B (fi
Inventor
Jr Edward Jethro Cragoe
Jr Otto William Woltersdorf
Jr Warren Kenneth Russ
George Gustave Hazen
Earl Martin Chamberlin
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/492,652 external-priority patent/US3981888A/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of FI278974A publication Critical patent/FI278974A/fi
Priority to FI800415A priority Critical patent/FI60388C/fi
Application granted granted Critical
Publication of FI61866B publication Critical patent/FI61866B/fi
Publication of FI61866C publication Critical patent/FI61866C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/88—Unsaturated compounds containing keto groups containing halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/86—Unsaturated compounds containing keto groups containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI2789/74A 1973-10-11 1974-09-25 Foerfarande foer framstaellning av diuretisk eller saluretisk (1-oxo-2-fenyl- eller -tienyl-2-substituerad-5-indanyloxi)aettiksyra eller dess derivat FI61866C (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI800415A FI60388C (fi) 1973-10-11 1980-02-11 Foerfarande foer framstaellning av (1-oxo-2-(4-hydroxifenyl)-2-metyl-6,7-diklor-5-indanyloxi)aettiksyra med diuretisk och saluretisk verkan

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US40573673A 1973-10-11 1973-10-11
US40573673 1973-10-11
US49265374A 1974-07-30 1974-07-30
US49265174A 1974-07-30 1974-07-30
US49265374 1974-07-30
US05/492,652 US3981888A (en) 1974-07-30 1974-07-30 Process for preparing (1-oxo-2-phenyl, halophenyl or thienyl-2-methyl-6,7-dichloro-5-indanyloxy)acetic acid
US49265274 1974-07-30
US49265174 1974-07-30

Publications (3)

Publication Number Publication Date
FI278974A FI278974A (sv) 1975-04-12
FI61866B FI61866B (fi) 1982-06-30
FI61866C true FI61866C (fi) 1982-10-11

Family

ID=27503519

Family Applications (1)

Application Number Title Priority Date Filing Date
FI2789/74A FI61866C (fi) 1973-10-11 1974-09-25 Foerfarande foer framstaellning av diuretisk eller saluretisk (1-oxo-2-fenyl- eller -tienyl-2-substituerad-5-indanyloxi)aettiksyra eller dess derivat

Country Status (4)

Country Link
DK (1) DK143553C (sv)
FI (1) FI61866C (sv)
NO (1) NO147747C (sv)
SE (1) SE423990B (sv)

Also Published As

Publication number Publication date
NO743495L (sv) 1975-05-05
DK143553C (da) 1982-02-15
FI278974A (sv) 1975-04-12
SE423990B (sv) 1982-06-21
SE7412046L (sv) 1975-04-14
FI61866B (fi) 1982-06-30
DK506674A (sv) 1975-06-09
DK143553B (da) 1981-09-07
NO147747B (no) 1983-02-28
NO147747C (no) 1983-06-08

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