FI57260C - Foerfarande foer framstaellning av terapeutiskt verksamma 2-amino-3,4-dihydro-5-metyl-imidazo-/5,1-f/-as-triaziner - Google Patents
Foerfarande foer framstaellning av terapeutiskt verksamma 2-amino-3,4-dihydro-5-metyl-imidazo-/5,1-f/-as-triaziner Download PDFInfo
- Publication number
- FI57260C FI57260C FI3900/73A FI390073A FI57260C FI 57260 C FI57260 C FI 57260C FI 3900/73 A FI3900/73 A FI 3900/73A FI 390073 A FI390073 A FI 390073A FI 57260 C FI57260 C FI 57260C
- Authority
- FI
- Finland
- Prior art keywords
- group
- carbon atoms
- dihydro
- amino
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI793137A FI793137A (fi) | 1973-01-04 | 1979-10-10 | Foerfarande foer framstaellning av terapeutiskt verksamma 2-amino-3-hydro-imidazotriaziner |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB55373*[A GB1457873A (en) | 1973-01-04 | 1973-01-04 | Imidazotriazines |
GB55373 | 1973-01-04 |
Publications (2)
Publication Number | Publication Date |
---|---|
FI57260B FI57260B (fi) | 1980-03-31 |
FI57260C true FI57260C (fi) | 1980-07-10 |
Family
ID=9706420
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI3900/73A FI57260C (fi) | 1973-01-04 | 1973-12-18 | Foerfarande foer framstaellning av terapeutiskt verksamma 2-amino-3,4-dihydro-5-metyl-imidazo-/5,1-f/-as-triaziner |
Country Status (19)
Country | Link |
---|---|
US (1) | US3941785A (ja) |
JP (1) | JPS4995994A (ja) |
AT (1) | AT336029B (ja) |
AU (1) | AU474078B2 (ja) |
BE (1) | BE809369A (ja) |
CA (1) | CA1005057A (ja) |
CH (1) | CH618170A5 (ja) |
DE (1) | DE2364076A1 (ja) |
ES (1) | ES422001A1 (ja) |
FI (1) | FI57260C (ja) |
FR (1) | FR2213058B1 (ja) |
GB (1) | GB1457873A (ja) |
IE (1) | IE38681B1 (ja) |
IL (1) | IL43872A (ja) |
LU (1) | LU69099A1 (ja) |
NL (1) | NL7400095A (ja) |
NO (1) | NO140301C (ja) |
SE (1) | SE408179B (ja) |
ZA (1) | ZA739534B (ja) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK109578A (da) * | 1977-03-25 | 1978-09-26 | Allen & Hanburys Ltd | Fremgangsmaade til fremstilling af heterocycliske forbindelser |
US4096257A (en) * | 1977-05-23 | 1978-06-20 | American Cyanamid Company | Substituted imidazo [1,2-d]-as-triazines |
US4107309A (en) * | 1977-05-23 | 1978-08-15 | American Cyanamid Company | Substituted imidazo[1,2-d]-as-triazines |
US4126444A (en) * | 1977-11-22 | 1978-11-21 | American Cynamid Company | Substituted imidazo (1,5-D)-as-triazin-4-ols, and herbicidal use thereof |
US4308384A (en) * | 1978-09-18 | 1981-12-29 | Glaxo Group Limited | Production of triazinones |
DD244681A3 (de) * | 1985-12-02 | 1987-04-15 | Zeiss Jena Veb Carl | Vorrichtung zur positionierung von enden flexibler lichtleitelemente |
US6624181B1 (en) * | 1997-02-28 | 2003-09-23 | Altana Pharma Ag | Synergistic combination |
GB2346877B (en) | 1997-11-12 | 2001-12-05 | Bayer Ag | 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors |
DE19827640A1 (de) * | 1998-06-20 | 1999-12-23 | Bayer Ag | 7-Alkyl- und Cycloalkyl-substituierte Imidazotriazinone |
CA2341488A1 (en) | 1998-08-26 | 2000-03-09 | Smithkline Beecham Corporation | Therapies for treating pulmonary diseases |
AU777012B2 (en) * | 1999-08-21 | 2004-09-30 | Takeda Gmbh | Synergistic combination of PDE inhibitors and beta 2 adrenoceptor agonist |
ATE348618T1 (de) * | 2001-05-09 | 2007-01-15 | Bayer Healthcare Ag | Neue verwendung von 2-(2-ethoxy-5-(4-methyl- piperazin-1-sulfonyl)-phenyl)-5-methyl-7-propyl 3h-imidazo(5,1-f)(1,2,4)triazin-4-on |
GB0113344D0 (en) * | 2001-06-01 | 2001-07-25 | Bayer Ag | Novel heterocycles 3 |
GB0113343D0 (en) * | 2001-06-01 | 2001-07-25 | Bayer Ag | Novel Heterocycles 2 |
DE10130167A1 (de) * | 2001-06-22 | 2003-01-02 | Bayer Ag | Imidazotriazine |
DE10135815A1 (de) | 2001-07-23 | 2003-02-06 | Bayer Ag | Verwendung von 2-Alkoxyphenyl-substituierten Imidazotriazinonen |
DE10230604A1 (de) * | 2002-07-08 | 2004-01-29 | Bayer Ag | Heterocyclisch substituierte Imidazotriazine |
DE10230605A1 (de) * | 2002-07-08 | 2004-01-29 | Bayer Ag | Substituierte Imidazotriazine |
DE10232113A1 (de) | 2002-07-16 | 2004-01-29 | Bayer Ag | Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel |
EP1608656B1 (en) * | 2003-04-01 | 2009-06-03 | SmithKline Beecham Corporation | Imidazotriazine compounds for the treatment of cancer diseases |
DE102005001989A1 (de) * | 2005-01-15 | 2006-07-20 | Bayer Healthcare Ag | Intravenöse Formulierungen von PDE-Inhibitoren |
DE102005009240A1 (de) * | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften |
DE102005009241A1 (de) * | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Arzneiformen mit kontrollierter Bioverfügbarkeit |
EP2258358A3 (en) | 2005-08-26 | 2011-09-07 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
AU2006282896A1 (en) | 2005-08-26 | 2007-03-01 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
KR20080056250A (ko) * | 2005-09-29 | 2008-06-20 | 바이엘 헬스케어 아게 | 비뇨기 장애의 치료를 위한 pde 억제제 및 이들의 조합 |
EP1940389A2 (en) | 2005-10-21 | 2008-07-09 | Braincells, Inc. | Modulation of neurogenesis by pde inhibition |
CA2625210A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
CA2643199A1 (en) * | 2006-03-08 | 2007-09-13 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
US7678808B2 (en) | 2006-05-09 | 2010-03-16 | Braincells, Inc. | 5 HT receptor mediated neurogenesis |
EP2382975A3 (en) | 2006-05-09 | 2012-02-29 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
US20100009983A1 (en) * | 2006-05-09 | 2010-01-14 | Braincells, Inc. | 5 ht receptor mediated neurogenesis |
JP2010502722A (ja) * | 2006-09-08 | 2010-01-28 | ブレインセルス,インコーポレイティド | 4−アシルアミノピリジン誘導体を含む組み合わせ |
WO2008036678A2 (en) * | 2006-09-19 | 2008-03-27 | Braincells, Inc. | Combination comprising a peroxisome proliferator activated receptor agent and a second neurogenic agent for treating a nervous system disorder, increasing neurodifferentiation and increasing neurogenesis |
US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
EP2167057A1 (en) * | 2007-06-13 | 2010-03-31 | Bayer HealthCare AG | Pde inhibitors for the treatment of hearing impairment |
WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
WO2013106547A1 (en) | 2012-01-10 | 2013-07-18 | President And Fellows Of Harvard College | Beta-cell replication promoting compounds and methods of their use |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE791025A (fr) * | 1971-11-19 | 1973-05-07 | Allen & Hanburys Ltd | Composes heterocycliques |
-
1973
- 1973-01-04 GB GB55373*[A patent/GB1457873A/en not_active Expired
- 1973-12-18 NO NO4843/73A patent/NO140301C/no unknown
- 1973-12-18 FI FI3900/73A patent/FI57260C/fi active
- 1973-12-18 ZA ZA739534A patent/ZA739534B/xx unknown
- 1973-12-19 AU AU63774/73A patent/AU474078B2/en not_active Expired
- 1973-12-20 IL IL43872A patent/IL43872A/xx unknown
- 1973-12-21 DE DE2364076A patent/DE2364076A1/de not_active Withdrawn
- 1973-12-26 US US05/427,558 patent/US3941785A/en not_active Expired - Lifetime
- 1973-12-28 FR FR7346979A patent/FR2213058B1/fr not_active Expired
- 1973-12-28 CA CA189,199A patent/CA1005057A/en not_active Expired
- 1973-12-31 JP JP49004782A patent/JPS4995994A/ja active Pending
- 1973-12-31 IE IE2345/73A patent/IE38681B1/xx unknown
-
1974
- 1974-01-02 LU LU69099A patent/LU69099A1/xx unknown
- 1974-01-02 AT AT2374A patent/AT336029B/de not_active IP Right Cessation
- 1974-01-02 CH CH9274A patent/CH618170A5/de not_active IP Right Cessation
- 1974-01-03 SE SE7400062A patent/SE408179B/xx unknown
- 1974-01-03 BE BE139496A patent/BE809369A/xx unknown
- 1974-01-03 ES ES422001A patent/ES422001A1/es not_active Expired
- 1974-01-04 NL NL7400095A patent/NL7400095A/xx not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
FR2213058A1 (ja) | 1974-08-02 |
BE809369A (fr) | 1974-07-03 |
ES422001A1 (es) | 1976-08-01 |
DE2364076A1 (de) | 1974-07-18 |
ATA2374A (de) | 1976-08-15 |
IL43872A0 (en) | 1974-03-14 |
NO140301B (no) | 1979-04-30 |
CA1005057A (en) | 1977-02-08 |
FR2213058B1 (ja) | 1977-07-01 |
SE408179B (sv) | 1979-05-21 |
GB1457873A (en) | 1976-12-08 |
CH618170A5 (ja) | 1980-07-15 |
NL7400095A (ja) | 1974-07-08 |
LU69099A1 (ja) | 1974-04-02 |
JPS4995994A (ja) | 1974-09-11 |
IL43872A (en) | 1979-01-31 |
NO140301C (no) | 1979-08-08 |
IE38681L (en) | 1974-07-04 |
AU474078B2 (en) | 1976-07-15 |
AT336029B (de) | 1977-04-12 |
FI57260B (fi) | 1980-03-31 |
ZA739534B (en) | 1974-11-27 |
AU6377473A (en) | 1975-06-19 |
IE38681B1 (en) | 1978-05-10 |
US3941785A (en) | 1976-03-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FI57260C (fi) | Foerfarande foer framstaellning av terapeutiskt verksamma 2-amino-3,4-dihydro-5-metyl-imidazo-/5,1-f/-as-triaziner | |
US3812127A (en) | 4-(quinolin-4-yl)piperazine-1-carboxylic acid esters | |
FI78097B (fi) | Foerfarande foer framstaellning av terapeutiskt anvaendbara (2-oxo-1,2,3,5-tatrahydroimidazo/2,1-b/ kinazolinyl)oxialkylamider. | |
Daly et al. | Analogs of caffeine and theophylline: Effect of structural alterations on affinity at adenosine receptors | |
US3702849A (en) | 4-(isoquinolin-1-yl) piperazine-1-carboxylic acid esters | |
EP0591528B1 (en) | PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVE AND ANTI-INFLAMMATORY CONTAINING THE SAME | |
US4289776A (en) | Xanthine derivatives | |
US5866580A (en) | Quinazoline derivatives and methods of using the same | |
CZ342595A3 (en) | Purine derivatives, process of their preparation and pharmaceutical compositions containing thereof | |
PL212407B1 (pl) | Zwiazek pochodny 8-chinolinoksantyny i 8-izochinolinoksantyny, jego zastosowanie, kompozycja farmaceutyczna zawierajaca zwiazek oraz sposób wytwarzania zwiazku | |
US4783530A (en) | 8-arylxanthines | |
NO134212B (ja) | ||
US4276295A (en) | 3-Aromatic moiety substituted-4(3H)-quinazolinones, process for production thereof, and use thereof | |
Sakai et al. | Effects of alkyl substitutions of xanthine skeleton on bronchodilation | |
Novinson et al. | Adenosine cyclic 3', 5'-monophosphate phosphodiesterase inhibitors. 2. 3-Substituted 5, 7-dialkylpyrazolo [1, 5-a] pyrimidines | |
US4822800A (en) | Isoquinolinol compounds having cardiotonic and phosphodiesterase fraction III inhibiting properties and/or renal vasodilating properties | |
US5314890A (en) | 1-7 disubstituted xanthine derivatives having antiasthmatic activity, their physiologically acceptable salts, pharmaceutical compositions containing them and process for their preparation | |
US5342841A (en) | Xanthine derivatives | |
US4801590A (en) | Pyrido(1,8)naphthyridinones, and their use as pharmaceuticals | |
Sinha et al. | Synthesis and antitumor properties of bis (quinaldine) derivatives | |
US5278186A (en) | Chromene derivatives, their production and use | |
US5378844A (en) | 8-(1-aminocycloalkyl)-1,3-dialkylxanthine derivatives, preparation process and antidepressant, nootropic and psychostimulant composition thereoff | |
US4176183A (en) | Novel naphthyridines | |
US6114339A (en) | Derivatives of pyrido [2,3-D] and [3,2-D] pyrimidine method of using these derivatives | |
DD236523A5 (de) | Verfahren zur herstellung von chinolon- und naphtyridoncarbonsaeuren |