FI50932C - A process for the preparation of polyhydroxyphenylchromes belonging to the silymarin group having a cell structure and cell metabolism stabilizing effect and possibly for the separation of silymarin I. - Google Patents

A process for the preparation of polyhydroxyphenylchromes belonging to the silymarin group having a cell structure and cell metabolism stabilizing effect and possibly for the separation of silymarin I.

Info

Publication number
FI50932C
FI50932C FI701253A FI125370A FI50932C FI 50932 C FI50932 C FI 50932C FI 701253 A FI701253 A FI 701253A FI 125370 A FI125370 A FI 125370A FI 50932 C FI50932 C FI 50932C
Authority
FI
Finland
Prior art keywords
silymarin
polyhydroxyphenylchromes
belonging
possibly
separation
Prior art date
Application number
FI701253A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI50932B (en
Inventor
Rolf Hermann Heinrich Madaus
Original Assignee
Madaus & Co Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Madaus & Co Dr filed Critical Madaus & Co Dr
Application granted granted Critical
Publication of FI50932B publication Critical patent/FI50932B/fi
Publication of FI50932C publication Critical patent/FI50932C/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/40Separation, e.g. from natural material; Purification
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI701253A 1969-05-06 1970-05-05 A process for the preparation of polyhydroxyphenylchromes belonging to the silymarin group having a cell structure and cell metabolism stabilizing effect and possibly for the separation of silymarin I. FI50932C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1923082A DE1923082C3 (en) 1969-05-06 1969-05-06 Process for the production of polyhydroxyphenylchromanones (Silymarin I-IV) and medicaments containing the polyhydroxyphenylchromanone (Silymarin I-IV = Silymarin I-IV group) mixture

Publications (2)

Publication Number Publication Date
FI50932B FI50932B (en) 1976-05-31
FI50932C true FI50932C (en) 1976-09-10

Family

ID=5733385

Family Applications (1)

Application Number Title Priority Date Filing Date
FI701253A FI50932C (en) 1969-05-06 1970-05-05 A process for the preparation of polyhydroxyphenylchromes belonging to the silymarin group having a cell structure and cell metabolism stabilizing effect and possibly for the separation of silymarin I.

Country Status (11)

Country Link
AT (1) AT290723B (en)
CH (1) CH541554A (en)
CS (1) CS162722B2 (en)
DE (1) DE1923082C3 (en)
ES (1) ES367906A1 (en)
FI (1) FI50932C (en)
IE (1) IE34110B1 (en)
IL (1) IL34381A (en)
NO (1) NO130345B (en)
PL (1) PL80560B1 (en)
YU (1) YU37065B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2428680C2 (en) * 1974-06-14 1983-02-17 Dr. Madaus & Co, 5000 Köln 1- (2 ', 4', 6'-trihydroxyphenyl) propanedione (1,2) compounds, processes for their preparation and pharmaceuticals containing these compounds
DE3537656A1 (en) * 1984-11-22 1986-05-22 Dr. Madaus GmbH & Co, 5000 Köln METHOD FOR PRODUCING ISOSILYBIN-FREE SILIBININE AND MEDICINAL PRODUCTS CONTAINING SILIBININE
FR2594691B1 (en) * 1986-02-24 1990-08-03 Bonne Claude NEW COSMETIC PREPARATIONS CONTAINING EXTRACT OF SILYBUM MARIANUM FRUITS
DE4401902C2 (en) * 1994-01-24 2000-02-03 Madaus Ag Use of flavolignans as an adjuvant in tumor therapy
EP2959910A1 (en) 2014-06-26 2015-12-30 Bionorica Se Milk thistle extract of fruit shells of Silybum marianum, process of manufacture and use

Also Published As

Publication number Publication date
IL34381A0 (en) 1970-06-17
DE1923082C3 (en) 1985-08-22
ES367906A1 (en) 1971-04-16
DE1923082B2 (en) 1974-09-19
CS162722B2 (en) 1975-07-15
YU37065B (en) 1984-08-31
IE34110B1 (en) 1975-02-05
YU112970A (en) 1983-04-27
PL80560B1 (en) 1975-08-30
IE34110L (en) 1970-11-06
DE1923082A1 (en) 1970-11-19
CH541554A (en) 1973-09-15
IL34381A (en) 1973-06-29
AT290723B (en) 1971-06-11
FI50932B (en) 1976-05-31
NO130345B (en) 1974-08-19

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