ES367906A1 - Procedure for the obtaining of polyhydroxypenyl-stabilizing creams of the cellular structure and the cytometabolism (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the obtaining of polyhydroxypenyl-stabilizing creams of the cellular structure and the cytometabolism (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES367906A1
ES367906A1 ES367906A ES367906A ES367906A1 ES 367906 A1 ES367906 A1 ES 367906A1 ES 367906 A ES367906 A ES 367906A ES 367906 A ES367906 A ES 367906A ES 367906 A1 ES367906 A1 ES 367906A1
Authority
ES
Spain
Prior art keywords
solvent system
cytometabolism
stabilizing
translation
residue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES367906A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Madaus Holding GmbH
Original Assignee
Dr Madaus GmbH and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Madaus GmbH and Co filed Critical Dr Madaus GmbH and Co
Publication of ES367906A1 publication Critical patent/ES367906A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/40—Separation, e.g. from natural material; Purification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

Process for obtaining polyhydroxyphenylchromones stabilizing the cell structure and cytometabolism, characterized by tearing, in the cellular complex, by means of great mechanical pressure, preferably in a helical press, dried fruits of silybum marianum gaertn., to exonerate them from the main quantity of the oil fatty; extracting thoroughly with ethyl acetate the press residue still having a residual oil content of 5 to 10%; evaporate the ethyl acetate; dissolve in 2% by weight, in the lower phase of a solvent system suitable for the separation of the undesired concomitant substances, for example the solvent system constituted essentially by methanol and petroleum ether, the dry, oily-crass residue and partially lumpy, containing about 20 to 30% active matter; centrifuge to clarify and remove the flocculent particles of solid matter; the residue in said solvent system is subjected to the multiplicative, preferably uniform, countercurrent distribution; a brownish powder containing 70 to 80% polyhydroxyphenylchromones is separated from the lower leaving phase by concentration in vacuo; and optionally, the silymarin i, which during the concentration is segregated in the form of a white to ocher crystallized, is already directly separated from the lower phase. (Machine-translation by Google Translate, not legally binding)
ES367906A 1969-05-06 1969-05-31 Procedure for the obtaining of polyhydroxypenyl-stabilizing creams of the cellular structure and the cytometabolism (Machine-translation by Google Translate, not legally binding) Expired ES367906A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1923082A DE1923082C3 (en) 1969-05-06 1969-05-06 Process for the production of polyhydroxyphenylchromanones (Silymarin I-IV) and medicaments containing the polyhydroxyphenylchromanone (Silymarin I-IV = Silymarin I-IV group) mixture

Publications (1)

Publication Number Publication Date
ES367906A1 true ES367906A1 (en) 1971-04-16

Family

ID=5733385

Family Applications (1)

Application Number Title Priority Date Filing Date
ES367906A Expired ES367906A1 (en) 1969-05-06 1969-05-31 Procedure for the obtaining of polyhydroxypenyl-stabilizing creams of the cellular structure and the cytometabolism (Machine-translation by Google Translate, not legally binding)

Country Status (11)

Country Link
AT (1) AT290723B (en)
CH (1) CH541554A (en)
CS (1) CS162722B2 (en)
DE (1) DE1923082C3 (en)
ES (1) ES367906A1 (en)
FI (1) FI50932C (en)
IE (1) IE34110B1 (en)
IL (1) IL34381A (en)
NO (1) NO130345B (en)
PL (1) PL80560B1 (en)
YU (1) YU37065B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2428680C2 (en) * 1974-06-14 1983-02-17 Dr. Madaus & Co, 5000 Köln 1- (2 ', 4', 6'-trihydroxyphenyl) propanedione (1,2) compounds, processes for their preparation and pharmaceuticals containing these compounds
DE3537656A1 (en) * 1984-11-22 1986-05-22 Dr. Madaus GmbH & Co, 5000 Köln METHOD FOR PRODUCING ISOSILYBIN-FREE SILIBININE AND MEDICINAL PRODUCTS CONTAINING SILIBININE
FR2594691B1 (en) * 1986-02-24 1990-08-03 Bonne Claude NEW COSMETIC PREPARATIONS CONTAINING EXTRACT OF SILYBUM MARIANUM FRUITS
DE4401902C2 (en) * 1994-01-24 2000-02-03 Madaus Ag Use of flavolignans as an adjuvant in tumor therapy
EP2959910A1 (en) 2014-06-26 2015-12-30 Bionorica Se Milk thistle extract of fruit shells of Silybum marianum, process of manufacture and use

Also Published As

Publication number Publication date
AT290723B (en) 1971-06-11
NO130345B (en) 1974-08-19
CS162722B2 (en) 1975-07-15
FI50932B (en) 1976-05-31
YU112970A (en) 1983-04-27
DE1923082A1 (en) 1970-11-19
DE1923082B2 (en) 1974-09-19
IL34381A0 (en) 1970-06-17
CH541554A (en) 1973-09-15
IE34110L (en) 1970-11-06
FI50932C (en) 1976-09-10
IE34110B1 (en) 1975-02-05
DE1923082C3 (en) 1985-08-22
YU37065B (en) 1984-08-31
PL80560B1 (en) 1975-08-30
IL34381A (en) 1973-06-29

Similar Documents

Publication Publication Date Title
ES410224A1 (en) Encapsulating substantially soluble portion of core material in substantially soluble shell material of different solubility
ZA743429B (en) Process for desolventizing solvent extracted from oleaginous seed material
ES367906A1 (en) Procedure for the obtaining of polyhydroxypenyl-stabilizing creams of the cellular structure and the cytometabolism (Machine-translation by Google Translate, not legally binding)
GB1023570A (en) Improvements in or relating to a nitrocellulose product and process of manufacture
GB1355272A (en) Method for the recovery of desmosterol -c27h44o- and derivatives thereof from vegetable products
JPS5686103A (en) Base for mosquito-repellent incense
ES326303A1 (en) A procedure to separate grease of biological substances. (Machine-translation by Google Translate, not legally binding)
US3288148A (en) Method of producing tobacco foils
ES410435A1 (en) Immunostimulant agent compositions thereof and methods for their preparation
US2522560A (en) Method for the stabilization of soft roes of fish and product obtained thereby
GB1257956A (en)
ES405736A1 (en) Treatment of sewage
SE8205282D0 (en) SIMILAR EXTRACTIONS OF LIPIDS AND POLYPHENOLS FROM FLING-SOLAR SOFTWARE
GB1420771A (en) Solid-liquid packed bed extraction
US2042938A (en) Refining vegetable material
ES253285A1 (en) Process for the production of protein enriched material from protein-containing materials having a relatively high water content
US765943A (en) Process of making a substitute for cod-liver oil.
ES392489A1 (en) Separation of fat from meat or fish
ES392681A1 (en) Process for leaching strontium sulfide black ash
KR910017967A (en) Manufacturing method of food material containing large amount of plant fiber from degreasing rice bran
US2324063A (en) Process of producing fat-soluble vitamin concentrates
ES268540A1 (en) Procedure for the continuous manufacture of an extract of vegetable products in the form of dust (Machine-translation by Google Translate, not legally binding)
FR2253466A1 (en) Deodorisation of fish foodstuffs - by removal of water by evaporation, partic. for "nuoc mam"
TH440EX (en) Extraction of oil from plant material
KR870002849A (en) Separation of asiaticoside, asiatic acid and madeic acid from centella