FI48093C - Analogimenetelmä valmistaa 1,3,4,5-tetrahydro-5-(2-(3-pyridyyli)-etyyl i)-2H-pyrido(4,3-b)indoleja, joilla on antihistamiininen, antiallergin en ja anafylaktista shokkia estävä vaikutus - Google Patents

Analogimenetelmä valmistaa 1,3,4,5-tetrahydro-5-(2-(3-pyridyyli)-etyyl i)-2H-pyrido(4,3-b)indoleja, joilla on antihistamiininen, antiallergin en ja anafylaktista shokkia estävä vaikutus

Info

Publication number
FI48093C
FI48093C FI671366A FI136667A FI48093C FI 48093 C FI48093 C FI 48093C FI 671366 A FI671366 A FI 671366A FI 136667 A FI136667 A FI 136667A FI 48093 C FI48093 C FI 48093C
Authority
FI
Finland
Prior art keywords
antihistamine
antiallergic
indoles
pyrido
tetrahydro
Prior art date
Application number
FI671366A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI48093B (en:Method
Inventor
Berger
Corraz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI48093B publication Critical patent/FI48093B/fi
Application granted granted Critical
Publication of FI48093C publication Critical patent/FI48093C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/42—Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
FI671366A 1966-05-12 1967-05-12 Analogimenetelmä valmistaa 1,3,4,5-tetrahydro-5-(2-(3-pyridyyli)-etyyl i)-2H-pyrido(4,3-b)indoleja, joilla on antihistamiininen, antiallergin en ja anafylaktista shokkia estävä vaikutus FI48093C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54945566A 1966-05-12 1966-05-12
US628530A US3409628A (en) 1966-05-12 1967-04-05 5-(3-pyridylethyl)pyridoindole derivatives

Publications (2)

Publication Number Publication Date
FI48093B FI48093B (en:Method) 1974-02-28
FI48093C true FI48093C (fi) 1974-06-10

Family

ID=27069138

Family Applications (1)

Application Number Title Priority Date Filing Date
FI671366A FI48093C (fi) 1966-05-12 1967-05-12 Analogimenetelmä valmistaa 1,3,4,5-tetrahydro-5-(2-(3-pyridyyli)-etyyl i)-2H-pyrido(4,3-b)indoleja, joilla on antihistamiininen, antiallergin en ja anafylaktista shokkia estävä vaikutus

Country Status (14)

Country Link
US (1) US3409628A (en:Method)
BE (1) BE698183A (en:Method)
CH (1) CH494234A (en:Method)
DE (1) DE1695187A1 (en:Method)
DK (1) DK123655B (en:Method)
ES (1) ES340412A1 (en:Method)
FI (1) FI48093C (en:Method)
FR (2) FR7024M (en:Method)
GB (3) GB1173997A (en:Method)
IL (1) IL27956A (en:Method)
NL (1) NL6706671A (en:Method)
NO (1) NO123950B (en:Method)
SE (1) SE342231B (en:Method)
YU (1) YU94367A (en:Method)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4696930A (en) * 1985-04-12 1987-09-29 Hoffmann-La Roche Inc. N-(heteroarylalkyl)acylanilide derivatives as antiarrhythmic agents
RU2339637C1 (ru) * 2007-04-05 2008-11-27 Андрей Александрович Иващенко Блокаторы гистаминного рецептора для фармацевтических композиций, обладающих противоаллергическим и аутоиммунным действием
CA2700160A1 (en) * 2007-09-20 2009-03-26 D2E, Llc Fluoro-containing derivatives of hydrogenated pyrido[4,3-b]indoles with neuroprotective and cognition enhancing properties, process for preparing, and use
RU2007139634A (ru) 2007-10-25 2009-04-27 Сергей Олегович Бачурин (RU) Новые тиазол-, триазол- или оксадиазол-содержащие тетрациклические соединения
WO2009082268A2 (ru) * 2007-12-21 2009-07-02 Alla Chem, Llc ЛИГАНДЫ α-АДРЕНОЦЕПТОРОВ, ДОПАМИНОВЫХ, ГИСТАМИНОВЫХ, ИМИДАЗОЛИНОВЫХ И СЕРОТОНИНОВЫХ РЕЦЕПТОРОВ И ИХ ПРИМЕНЕНИЕ
US9063126B2 (en) * 2008-09-29 2015-06-23 Abbvie Inc. Indole and indoline derivatives and methods of use thereof
US9625475B2 (en) * 2008-09-29 2017-04-18 Abbvie Inc. Indole and indoline derivatives and methods of use thereof
WO2010067085A2 (en) 2008-12-12 2010-06-17 Wista Laboratories Ltd. Synthesis of 9-(arylalkyl)-1,2,3,4-tetrahydro-υ-carboline and analogues and intermediates
US9162980B2 (en) 2009-01-09 2015-10-20 Board Of Regents Of The University Of Texas System Anti-depression compounds
US8362277B2 (en) 2009-01-09 2013-01-29 Board Of Regents Of The University Of Texas System Pro-neurogenic compounds
US9962368B2 (en) 2009-01-09 2018-05-08 Board Of Regents Of The University Of Texas System Pro-neurogenic compounds
CN107595841A (zh) * 2009-01-09 2018-01-19 得克萨斯州大学系统董事会 前神经原性化合物
BRPI1006602A2 (pt) 2009-04-29 2019-01-15 Medivation Technologies Inc composto, método para modular um receptor de histamina em um indivíduo, composição farmacêutica, kit e método para tratar um distúrbio cognitivo ou um distúrbio induzido por pelo menos um sintoma associado com a alteração da cognição
AU2010282990B2 (en) 2009-04-29 2015-11-05 Medivation Technologies, Inc. Pyrido [4, 3-b] indoles and methods of use
WO2011008312A2 (en) 2009-07-14 2011-01-20 Abbott Laboratories Indole and indoline derivatives and methods of use thereof
EP2590647B1 (en) 2010-07-07 2017-11-08 Board of Regents of the University of Texas System Pro-neurogenic compounds
US8791132B2 (en) 2011-02-18 2014-07-29 Medivation Technologies, Inc. Compounds and methods for treatment of hypertension
CA2882826A1 (en) 2012-08-24 2014-02-27 Board Of Regents Of The University Of Texas System Pro-neurogenic compounds
WO2015070237A1 (en) 2013-11-11 2015-05-14 Board Of Regents Of The University Of Texas System Neuroprotective chemicals and methods for identifying and using same
WO2015070234A2 (en) 2013-11-11 2015-05-14 Board Of Regents Of The University Of Texas System Neuroprotective compounds and use thereof
US12084440B2 (en) * 2021-02-01 2024-09-10 Bigespas Ltd. Polymorph of latrepirdine dihydrochloride

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2786059A (en) * 1951-04-30 1957-03-19 Schenley Ind Inc Derivatives of 2-nu-methyl-1, 2, 3, 4-tetrahydro-gamma-carbolines

Also Published As

Publication number Publication date
YU94367A (en) 1974-08-31
GB1173997A (en) 1969-12-10
SE342231B (en:Method) 1972-01-31
BE698183A (en:Method) 1967-11-09
FR1522686A (fr) 1968-04-26
CH494234A (de) 1970-07-31
FR7024M (en:Method) 1969-06-09
FI48093B (en:Method) 1974-02-28
NO123950B (en:Method) 1972-02-07
ES340412A1 (es) 1968-06-01
GB1173999A (en) 1969-12-10
GB1173998A (en) 1969-12-10
NL6706671A (en:Method) 1967-11-13
DK123655B (da) 1972-07-17
US3409628A (en) 1968-11-05
IL27956A (en) 1972-06-28
DE1695187A1 (de) 1971-04-08

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